Alg3 Mutant

H.J. Bosch (Inventor), S. van der Krol (Inventor), M.G.L. Henquet (Inventor), D.E.A. Florack (Inventor)

Research output: Patent


The present invention relates to a method to produce proteins reduced in high mannose type glycans in a plant or plant cell by partially inhibiting the expression of the Alg3 gene in said plant or plant cell. Said partial inhibition can be provided for by inserting the Alg3 mutant gene from Arabidopsis as derived from the plant line Salk_040296c or by partially inhibiting the endogenous Alg3 gene by providing the plant or plant cell either with an antisense expression, a sense co-suppressing or with an RNA inhibition genetic construct. Optionally also tissue-specific expression of said inhibiting constructs can yield partial inhibition in a plant.
Original languageEnglish
Patent numberWO2008143513
Priority date23/05/07
Publication statusPublished - 27 Nov 2008


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