Alcohol consumption and augmentation index in healthy young men: The ARYA study

M.J.C.A. Trijp, J.W.J. Beulens, W.J.W. Bos, C.S.P.M. Uiterwaal, D.E. Grobbee, H.F.J. Hendriks, M.L. Bots

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28 Citations (Scopus)


Light-to-moderate alcohol consumption is associated with a decreased risk of ischemic cardiovascular disease, whereas increased alcohol intake is related to hypertension and intracerebral hemorrhage. We studied the effect of alcohol consumption on the augmentation index (AIx), a measure of arterial wave reflection in a population of healthy young men. Methods: Three hundred twenty-nine men (mean age 28 years) from the Atherosclerosis Risk in Young Adults study (ARYA-study) were studied. The level of alcohol consumption and risk factors for cardiovascular disease were determined. The AIx was estimated by radial applanation tonometry using a Sphygmocor device. The relation between alcohol intake level and AIx was determined using linear regression models. Results: There was a positive graded relation between alcohol intake and AIx. Subjects who did not drink, who drank 1 to 2 glasses/d, or who drank ¿3 glasses of alcohol/d had, respectively, a -0.6% (95% confidence interval [CI] -4.2, 3.0), 0.2% (95% CI -2.6, 2.9), and 3.4% (95% CI 0.2, 6.7) difference in AIx compared with very light drinkers (3 glasses/d had a 3.29% (95% confidence interval CI 0.01, 6.7) higher AIx compared with those consuming
Original languageEnglish
Pages (from-to)792-796
JournalAmerican Journal of Hypertension
Issue number6
Publication statusPublished - 2005


  • arterial transfer-functions
  • wave-form characteristics
  • coronary-heart-disease
  • pulse pressure
  • aortic stiffness
  • risk
  • women
  • adults
  • atherosclerosis
  • hypertension


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