Alcohol acetyl transferases for ethyl acetate production

Aleksander J. Kruis; M. Levisson; A.E. Mars; S.W.M. Kengen; J. van der Oost; J.P.M. Sanders; R.A. Weusthuis

Alcohol acetyl transferases for ethyl acetate production

Aleksander J. Kruis (Inventor), M. Levisson (Inventor), A.E. Mars (Inventor), S.W.M. Kengen (Inventor), J. van der Oost (Inventor), J.P.M. Sanders (Inventor), R.A. Weusthuis (Inventor)

Research output: Patent

Abstract

The present invention relates to a process for the production of ethyl acetate wherein a polypeptide having alcohol acetyl transferase activity converts ethanol and acetyl coenzyme A into ethyl acetate. The polypeptide has an alpha-beta hydrolase fold and an active site comprising a serine, histidine, and optionally aspartic acid in its three-dimensional structure. The polypeptides according to the invention are genes isolated from Kluyveromyces marxianus, Kluyveromyces lactis, Wickerhamomyces ciferrii, Cyberlindnera jadinii, Hanseniaspora uvarum, Eremothecium cymbalarie and Saccharomyces cerevisiae.

Original language	English
Patent number	WO2018100097
Priority date	1/12/16
Publication status	Published - 7 Jun 2018

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title = "Alcohol acetyl transferases for ethyl acetate production",

abstract = "The present invention relates to a process for the production of ethyl acetate wherein a polypeptide having alcohol acetyl transferase activity converts ethanol and acetyl coenzyme A into ethyl acetate. The polypeptide has an alpha-beta hydrolase fold and an active site comprising a serine, histidine, and optionally aspartic acid in its three-dimensional structure. The polypeptides according to the invention are genes isolated from Kluyveromyces marxianus, Kluyveromyces lactis, Wickerhamomyces ciferrii, Cyberlindnera jadinii, Hanseniaspora uvarum, Eremothecium cymbalarie and Saccharomyces cerevisiae.",

author = "Kruis, {Aleksander J.} and M. Levisson and A.E. Mars and S.W.M. Kengen and {van der Oost}, J. and J.P.M. Sanders and R.A. Weusthuis",

year = "2018",

month = jun,

day = "7",

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type = "Patent",

note = "WO2018100097",

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TY - PAT

T1 - Alcohol acetyl transferases for ethyl acetate production

AU - Kruis, Aleksander J.

AU - Levisson, M.

AU - Mars, A.E.

AU - Kengen, S.W.M.

AU - van der Oost, J.

AU - Sanders, J.P.M.

AU - Weusthuis, R.A.

PY - 2018/6/7

Y1 - 2018/6/7

N2 - The present invention relates to a process for the production of ethyl acetate wherein a polypeptide having alcohol acetyl transferase activity converts ethanol and acetyl coenzyme A into ethyl acetate. The polypeptide has an alpha-beta hydrolase fold and an active site comprising a serine, histidine, and optionally aspartic acid in its three-dimensional structure. The polypeptides according to the invention are genes isolated from Kluyveromyces marxianus, Kluyveromyces lactis, Wickerhamomyces ciferrii, Cyberlindnera jadinii, Hanseniaspora uvarum, Eremothecium cymbalarie and Saccharomyces cerevisiae.

AB - The present invention relates to a process for the production of ethyl acetate wherein a polypeptide having alcohol acetyl transferase activity converts ethanol and acetyl coenzyme A into ethyl acetate. The polypeptide has an alpha-beta hydrolase fold and an active site comprising a serine, histidine, and optionally aspartic acid in its three-dimensional structure. The polypeptides according to the invention are genes isolated from Kluyveromyces marxianus, Kluyveromyces lactis, Wickerhamomyces ciferrii, Cyberlindnera jadinii, Hanseniaspora uvarum, Eremothecium cymbalarie and Saccharomyces cerevisiae.

M3 - Patent

M1 - WO2018100097

ER -

Alcohol acetyl transferases for ethyl acetate production

Abstract

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