Alcohol acetyl transferases for ethyl acetate production

Aleksander J. Kruis (Inventor), M. Levisson (Inventor), A.E. Mars (Inventor), S.W.M. Kengen (Inventor), J. van der Oost (Inventor), J.P.M. Sanders (Inventor), R.A. Weusthuis (Inventor)

Research output: Patent


The present invention relates to a process for the production of ethyl acetate wherein a polypeptide having alcohol acetyl transferase activity converts ethanol and acetyl coenzyme A into ethyl acetate. The polypeptide has an alpha-beta hydrolase fold and an active site comprising a serine, histidine, and optionally aspartic acid in its three-dimensional structure. The polypeptides according to the invention are genes isolated from Kluyveromyces marxianus, Kluyveromyces lactis, Wickerhamomyces ciferrii, Cyberlindnera jadinii, Hanseniaspora uvarum, Eremothecium cymbalarie and Saccharomyces cerevisiae.
Original languageEnglish
Patent numberWO2018100097
Priority date1/12/16
Publication statusPublished - 7 Jun 2018


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