Advances in Micro-Ultrahigh-Preformance Liquid Chromatography-Mass Spectrometry in Residue and Contaminant Analysis

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Abstract

Advances in nano-ultrahigh-performance liquid chromatography (nUHPLC) and "plug-and-play" micro-UHPLC (µUHPLC) for the detection of veterinary drugs and steroids in porcine meat and urine respectively are described. Recent developments in "plug-and-play" µUHPLC devices offer several advantages compared to earlier micro-LC systems. As well as the ease of use, solvent consumption can be reduced by more than 95% and the amount of sample required can be reduced 10-fold. In addition, the performance and the robustness of the µUHPLC sytem described is comparable to conventional UHPLC, and can be successfuly applied for the routine analysis of residues and contaminants in food.
Original languageEnglish
Pages (from-to)18-23
JournalLc Gc Europe
Volume32
Issue number5
Publication statusPublished - 2014

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