Adhesion of biocompatible and biodegradable micropatterned surfaces

J.S. Kaiser; M.M.G. Kamperman; E.J. Souza; B. Schick; E. Arzt

doi:10.5301/IJAO.2011.6393

Adhesion of biocompatible and biodegradable micropatterned surfaces

J.S. Kaiser, M.M.G. Kamperman, E.J. Souza, B. Schick, E. Arzt

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Research output: Contribution to journal › Article › Academic › peer-review

16 Citations (Scopus)

Abstract

We studied the effects of pillar dimensions and stiffness of biocompatible and biodegradable micropatterned surfaces on adhesion on different compliant substrates. The micropatterned adhesives were based on biocompatible polydimethylsiloxane (PDMS) and biodegradable poly(lactic-co-glycolic) acid (PLGA) polymer systems. Micropatterned and non-patterned compliant PDMS did not show significant differences in adhesion on compliant mice ear skin or on gelatin-glycerin model substrates. However, adhesion measurements for micropatterned stiff PLGA on compliant gelatin-glycerin model substrates showed significant enhancement in pull-off strengths compared to non-patterned controls.

Original language	English
Pages (from-to)	180-184
Journal	International Journal of Artificial Organs
Volume	34
Issue number	2
DOIs	https://doi.org/10.5301/IJAO.2011.6393
Publication status	Published - 2011

Keywords

gecko
force

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AU - Arzt, E.

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Adhesion of biocompatible and biodegradable micropatterned surfaces

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