ACE: accurate correction of errors using K-mer tries

S. Sheikhizadeh Anari, D. de Ridder

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Abstract

The quality of high-throughput next-generation sequencing data significantly influences the performance and memory consumption of assembly and mapping algorithms. The most ubiquitous platform, Illumina, mainly suffers from substitution errors. We have developed a tool, ACE, based on K-mer tries to correct such errors. On real MiSeq and HiSeq Illumina archives, ACE yields higher gains in terms of coverage depth, outperforming state-of-the-art competitors in the majority of cases.
Original languageEnglish
Pages (from-to)3216-3218
JournalBioinformatics
Volume31
Issue number19
DOIs
Publication statusPublished - 2015

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