Abstract
Cell suspension cultures of Linum album were established, which were able to synthesize and accumulate lignans. Podophyllotoxin and 5-methoxypodophyllotoxin were the main products and were present as glycosides, together with small amounts of deoxypodophyllotoxin, 5′-demethoxy-5-methoxypodophyllotoxin, lariciresinol, pinoresinol, matairesinol, α- and β-peltatin, as well as the monolignol glucoside, coniferin. In dark and light grown cultures, maximal product yields of lignans of up to 0.2% and 0.5% of the dry weight, respectively, were achieved, mainly consisting of podophyllotoxin.
Original language | English |
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Pages (from-to) | 975-979 |
Journal | Phytochemistry |
Volume | 48 |
Issue number | 6 |
DOIs | |
Publication status | Published - 1998 |
Keywords
- 5- Methoxypodophyllotoxin
- Biosynthesis
- Coniferin
- Lignans
- Linaceae
- Linum album
- Plant cell cultures
- Podophyllotoxin
- White flax