To manage Red Poultry Mite (RPM) in laying hen farms, a large project has bene carried out. With 20 commercial test farms the total concept IPM (Integrated Pest Management) has been tested and optimized. The RPM populations on these farms as well as on 10 control farms have been monitored. Monitoring has been optimized and an advice has been formed how this can best be done. The economic consequences of RPM are listed. For the use of chemicals against PRM an overview has been made of the allowed chemicals and under what legislation they are allowed. Also for new chemicals the possibilities are given for registration or obtaining allowance to use.