A SOSEKI-based coordinate system interprets global polarity cues in Arabidopsis

Saiko Yoshida*, Alja van der Schuren, Maritza van Dop, Luc van Galen, Shunsuke Saiga, Milad Adibi, Barbara Möller, Colette A. ten Hove, Peter Marhavy, Richard Smith, Jiri Friml, Dolf Weijers

*Corresponding author for this work

Research output: Contribution to journalLetterAcademicpeer-review

6 Citations (Scopus)

Abstract

Multicellular development requires coordinated cell polarization relative to body axes, and translation to oriented cell division 1–3 . In plants, it is unknown how cell polarities are connected to organismal axes and translated to division. Here, we identify Arabidopsis SOSEKI proteins that integrate apical–basal and radial organismal axes to localize to polar cell edges. Localization does not depend on tissue context, requires cell wall integrity and is defined by a transferrable, protein-specific motif. A Domain of Unknown Function in SOSEKI proteins resembles the DIX oligomerization domain in the animal Dishevelled polarity regulator. The DIX-like domain self-interacts and is required for edge localization and for influencing division orientation, together with a second domain that defines the polar membrane domain. Our work shows that SOSEKI proteins locally interpret global polarity cues and can influence cell division orientation. Furthermore, this work reveals that, despite fundamental differences, cell polarity mechanisms in plants and animals converge on a similar protein domain.

Original languageEnglish
Pages (from-to)160-166
Number of pages7
JournalNature Plants
Volume5
Issue number2
DOIs
Publication statusPublished - 1 Feb 2019

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Arabidopsis
proteins
cell division
translation (genetics)
animals
cell walls
cells
cell polarity

Cite this

Yoshida, S., van der Schuren, A., van Dop, M., van Galen, L., Saiga, S., Adibi, M., ... Weijers, D. (2019). A SOSEKI-based coordinate system interprets global polarity cues in Arabidopsis. Nature Plants, 5(2), 160-166. https://doi.org/10.1038/s41477-019-0363-6
Yoshida, Saiko ; van der Schuren, Alja ; van Dop, Maritza ; van Galen, Luc ; Saiga, Shunsuke ; Adibi, Milad ; Möller, Barbara ; ten Hove, Colette A. ; Marhavy, Peter ; Smith, Richard ; Friml, Jiri ; Weijers, Dolf. / A SOSEKI-based coordinate system interprets global polarity cues in Arabidopsis. In: Nature Plants. 2019 ; Vol. 5, No. 2. pp. 160-166.
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abstract = "Multicellular development requires coordinated cell polarization relative to body axes, and translation to oriented cell division 1–3 . In plants, it is unknown how cell polarities are connected to organismal axes and translated to division. Here, we identify Arabidopsis SOSEKI proteins that integrate apical–basal and radial organismal axes to localize to polar cell edges. Localization does not depend on tissue context, requires cell wall integrity and is defined by a transferrable, protein-specific motif. A Domain of Unknown Function in SOSEKI proteins resembles the DIX oligomerization domain in the animal Dishevelled polarity regulator. The DIX-like domain self-interacts and is required for edge localization and for influencing division orientation, together with a second domain that defines the polar membrane domain. Our work shows that SOSEKI proteins locally interpret global polarity cues and can influence cell division orientation. Furthermore, this work reveals that, despite fundamental differences, cell polarity mechanisms in plants and animals converge on a similar protein domain.",
author = "Saiko Yoshida and {van der Schuren}, Alja and {van Dop}, Maritza and {van Galen}, Luc and Shunsuke Saiga and Milad Adibi and Barbara M{\"o}ller and {ten Hove}, {Colette A.} and Peter Marhavy and Richard Smith and Jiri Friml and Dolf Weijers",
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Yoshida, S, van der Schuren, A, van Dop, M, van Galen, L, Saiga, S, Adibi, M, Möller, B, ten Hove, CA, Marhavy, P, Smith, R, Friml, J & Weijers, D 2019, 'A SOSEKI-based coordinate system interprets global polarity cues in Arabidopsis', Nature Plants, vol. 5, no. 2, pp. 160-166. https://doi.org/10.1038/s41477-019-0363-6

A SOSEKI-based coordinate system interprets global polarity cues in Arabidopsis. / Yoshida, Saiko; van der Schuren, Alja; van Dop, Maritza; van Galen, Luc; Saiga, Shunsuke; Adibi, Milad; Möller, Barbara; ten Hove, Colette A.; Marhavy, Peter; Smith, Richard; Friml, Jiri; Weijers, Dolf.

In: Nature Plants, Vol. 5, No. 2, 01.02.2019, p. 160-166.

Research output: Contribution to journalLetterAcademicpeer-review

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AU - Yoshida, Saiko

AU - van der Schuren, Alja

AU - van Dop, Maritza

AU - van Galen, Luc

AU - Saiga, Shunsuke

AU - Adibi, Milad

AU - Möller, Barbara

AU - ten Hove, Colette A.

AU - Marhavy, Peter

AU - Smith, Richard

AU - Friml, Jiri

AU - Weijers, Dolf

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AB - Multicellular development requires coordinated cell polarization relative to body axes, and translation to oriented cell division 1–3 . In plants, it is unknown how cell polarities are connected to organismal axes and translated to division. Here, we identify Arabidopsis SOSEKI proteins that integrate apical–basal and radial organismal axes to localize to polar cell edges. Localization does not depend on tissue context, requires cell wall integrity and is defined by a transferrable, protein-specific motif. A Domain of Unknown Function in SOSEKI proteins resembles the DIX oligomerization domain in the animal Dishevelled polarity regulator. The DIX-like domain self-interacts and is required for edge localization and for influencing division orientation, together with a second domain that defines the polar membrane domain. Our work shows that SOSEKI proteins locally interpret global polarity cues and can influence cell division orientation. Furthermore, this work reveals that, despite fundamental differences, cell polarity mechanisms in plants and animals converge on a similar protein domain.

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Yoshida S, van der Schuren A, van Dop M, van Galen L, Saiga S, Adibi M et al. A SOSEKI-based coordinate system interprets global polarity cues in Arabidopsis. Nature Plants. 2019 Feb 1;5(2):160-166. https://doi.org/10.1038/s41477-019-0363-6