Abstract
Encapsulation and controlled release of bioactive compounds is now an established protocol to enhance the bioavailability and long-lasting efficacy of therapeutic and disease-preventive agents while minimizing or eliminating side effects. Currently, there are a number of products approved by the regulatory authorities for Human or animal use, which contain encapsulated drugs, nutraceuticals, diagnostic agents, cosmetics, or even vaccines. Manufacturing the encapsulation/carrier systems requires special considerations with respect to scalability, environmental issues, and cost-effectiveness. Among the many available procedures for large-scale preparation of micro-and nanocarriers, the "Mozafari method" has proven to be simple to implement and reproducible technique that does not require sophisticated equipment or use of potentially toxic solvents. The mentioned proprietary method and patents in which this method is utilized or incorporated is the focus of the present review article.
| Original language | English |
|---|---|
| Article number | 34 |
| Journal | Biointerface Research in Applied Chemistry |
| Volume | 13 |
| Issue number | 1 |
| Early online date | 23 Jan 2022 |
| DOIs | |
| Publication status | Published - 15 Feb 2023 |
Keywords
- bioactive agents
- carrier vehicle
- drug delivery
- liposome
- nanoliposome
- solid lipid nanoparticle
- tocosome
