Broad-spectrum resistance in potato to the potato cyst nematode (PCN) species Globodera rostochiensis and G. pallida is commonly regarded as a polygenically inherited trait. Yet, by use of QTL analysis and a selected set of PCN populations, resistance to both PCN species could be ascribed to the action of locus Grp1. Grp1 confers major resistance to G. rostochiensis line Ro5-22 and G. pallida population Pa2-D383 and partial resistance to G. pallida population Pa3-Rookmaker. Grp1 was mapped on chromosome 5 using previously characterized AFLP markers. Cleaved amplified polymorphic sequence (CAPS) markers available for RFLP loci GP21 and GP179 revealed that Grp1 maps on a genomic region harboring other resistance factors to viral, fungal and nematodal pathogens. The present data indicate that Grp1 is a compound locus which contains multiple genes involved in PCN resistance.
Rouppe van der Voort, J. N. A. M., Lindeman, W., Folkertsma, R., Hutten, R. C. B., Overmars, H., van der Vossen, E., Jacobsen, E., & Bakker, J. (1998). A QTL for broad spectrum resistance to cyst nematode species (Globodera spp.) maps to a resistance gene cluster in potato. Theoretical and Applied Genetics, 96, 654-661. https://doi.org/10.1007/s001220050785