A new flexible synthesis of (D-homo) sterioids

F.C.E. Sarabèr; Æ. de Groot

doi:10.1016/j.tetlet.2004.10.102

A new flexible synthesis of (D-homo) sterioids

F.C.E. Sarabèr, Æ. de Groot

Organic Chemistry

Research output: Contribution to journal › Article › Academic › peer-review

9 Citations (Scopus)

Abstract

A short, flexible and efficient procedure has been developed for the synthesis of C17 substituted steroid skeletons and Dhomo steroid skeletons using a ZnBr2 catalysed coupling of a silyl enol ether containing ring D precursor with a Torgov type reagent, followed by acid catalysed cyclisation of the adducts to (D-homo) steroid skeletons. (C) 2004 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	9431-9433
Journal	Tetrahedron Letters
Volume	45
Issue number	51
DOIs	https://doi.org/10.1016/j.tetlet.2004.10.102
Publication status	Published - 2004

Keywords

optically-active steroids
derivatives
carbopalladation
skeletons
estrogens
estrone

Access to Document

10.1016/j.tetlet.2004.10.102

Cite this

@article{bbdaa03e2efb48a9971f09277d85ad3d,

title = "A new flexible synthesis of (D-homo) sterioids",

abstract = "A short, flexible and efficient procedure has been developed for the synthesis of C17 substituted steroid skeletons and Dhomo steroid skeletons using a ZnBr2 catalysed coupling of a silyl enol ether containing ring D precursor with a Torgov type reagent, followed by acid catalysed cyclisation of the adducts to (D-homo) steroid skeletons. (C) 2004 Elsevier Ltd. All rights reserved.",

keywords = "optically-active steroids, derivatives, carbopalladation, skeletons, estrogens, estrone",

author = "F.C.E. Sarab{\`e}r and {de Groot}, {\AE}.",

year = "2004",

doi = "10.1016/j.tetlet.2004.10.102",

language = "English",

volume = "45",

pages = "9431--9433",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier",

number = "51",

}

TY - JOUR

T1 - A new flexible synthesis of (D-homo) sterioids

AU - Sarabèr, F.C.E.

AU - de Groot, Æ.

PY - 2004

Y1 - 2004

N2 - A short, flexible and efficient procedure has been developed for the synthesis of C17 substituted steroid skeletons and Dhomo steroid skeletons using a ZnBr2 catalysed coupling of a silyl enol ether containing ring D precursor with a Torgov type reagent, followed by acid catalysed cyclisation of the adducts to (D-homo) steroid skeletons. (C) 2004 Elsevier Ltd. All rights reserved.

AB - A short, flexible and efficient procedure has been developed for the synthesis of C17 substituted steroid skeletons and Dhomo steroid skeletons using a ZnBr2 catalysed coupling of a silyl enol ether containing ring D precursor with a Torgov type reagent, followed by acid catalysed cyclisation of the adducts to (D-homo) steroid skeletons. (C) 2004 Elsevier Ltd. All rights reserved.

KW - optically-active steroids

KW - derivatives

KW - carbopalladation

KW - skeletons

KW - estrogens

KW - estrone

U2 - 10.1016/j.tetlet.2004.10.102

DO - 10.1016/j.tetlet.2004.10.102

M3 - Article

SN - 0040-4039

VL - 45

SP - 9431

EP - 9433

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 51

ER -

A new flexible synthesis of (D-homo) sterioids

Abstract

Keywords

Access to Document

Fingerprint

Cite this