A miniaturized optoelectronic system for rapid quantitative label-free detection of harmful species in food

Ioannis Raptis, Konstantinos Misiakos, Eleni Makarona, Alexandros Salapatas, Panagiota Petrou, Sotirios Kakabakos, Athanasios Botsialas, Gerhard Jobst, Willem Haasnoot, Amadeo Fernandez-Alba, Michelle Lees, Evangelos Valamontes

Research output: Chapter in Book/Report/Conference proceedingConference paperAcademicpeer-review

Abstract

Optical biosensors have emerged in the past decade as the most promising candidates for portable, highly-sensitive bioanalytical systems that can be employed for in-situ measurements. In this work, a miniaturized optoelectronic system for rapid, quantitative, label-free detection of harmful species in food is presented. The proposed system has four distinctive features that can render to a powerful tool for the next generation of Point-of-Need applications, namely it accommodates the light sources and ten interferometric biosensors on a single silicon chip of a less-than-40mm2 footprint, each sensor can be individually functionalized for a specific target analyte, the encapsulation can be performed at the wafer-scale, and finally it exploits a new operation principle, Broad-band Mach-Zehnder Interferometry to ameliorate its analytical capabilities. Multi-analyte evaluation schemes for the simultaneous detection of harmful contaminants, such as mycotoxins, allergens and pesticides, proved that the proposed system is capable of detecting within short time these substances at concentrations below the limits imposed by regulatory authorities, rendering it to a novel tool for the near-future food safety applications.

Original languageEnglish
Title of host publicationFrontiers in Biological Detection: From Nanosensors to Systems VIII
EditorsBenjamin L. Miller, Brian T. Cunningham, Amos Danielli, G. Logan Liu, Sharon M. Weiss
PublisherSPIE
ISBN (Print)9781628419597
DOIs
Publication statusPublished - 2016
EventFrontiers in Biological Detection: From Nanosensors to Systems VIII - San Francisco, United States
Duration: 14 Feb 201615 Feb 2016

Publication series

NameProgress in Biomedical Optics and Imaging
PublisherSPIE
Number37
Volume17

Conference

ConferenceFrontiers in Biological Detection: From Nanosensors to Systems VIII
CountryUnited States
CitySan Francisco
Period14/02/1615/02/16

Keywords

  • food safety
  • lab-on-a-chip
  • Mach-Zehnder interferometry
  • optoelectronic chip

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