A metabolic profile is associated with the risk of incident coronary heart disease

A. Vaarhorst, A. Verhoeven, C.M. Weller, S. Bohringer, P.A. van den Brandt, M.M. Greevenbroek, A.H. Merry, W.M.M. Verschuren, J.M.A. Boer, E.J.M. Feskens, B.T. Heijmans, P.E. Slagboom

Research output: Contribution to journalArticleAcademicpeer-review

36 Citations (Scopus)

Abstract

Background Metabolomics, defined as the comprehensive identification and quantification of low-molecular-weight metabolites to be found in a biological sample, has been put forward as a potential tool for classifying individuals according to their risk of coronary heart disease (CHD). Here, we investigated whether a single-point blood measurement of the metabolome is associated with and predictive for the risk of CHD.
Original languageEnglish
Pages (from-to)45-52.e7
JournalAmerican Heart Journal
Volume168
Issue number1
DOIs
Publication statusPublished - 2014

Keywords

  • artery-disease
  • cardiovascular events
  • population
  • prediction
  • plasma
  • phosphatidylcholine
  • metabonomics
  • netherlands
  • mortality
  • cohort

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