A large proportion of esophageal cancer cases and the incidence difference between regions are attributable to lifestyle risk factors in China

M. Wu; P. van 't Veer; Z.F. Zhang; X.S. Wang; X.P. Gu; R.Q. Han; J. Yang; X.F. Zhang; A.M. Liu; F.J. Kok; E. Kampman; J.K. Zhao

doi:10.1016/j.canlet.2011.05.003

A large proportion of esophageal cancer cases and the incidence difference between regions are attributable to lifestyle risk factors in China

M. Wu, P. van 't Veer, Z.F. Zhang, X.S. Wang, X.P. Gu, R.Q. Han, J. Yang, X.F. Zhang, A.M. Liu, F.J. Kok, E. Kampman, J.K. Zhao

Research output: Contribution to journal › Article › Academic › peer-review

26 Citations (Scopus)

Abstract

A population-based case-control study was conducted in a high-risk area (Dafeng) and a low-risk area (Ganyu) of Jiangsu province, China. In this analysis, the population attributable fraction (PAF) was calculated to quantify the etiology of risk factors; the relative attributable risk (RAR) was applied to explore how much of the incidence difference could be explained by variations in the distribution of risk factors. Results showed that unhealthy lifestyles accounted for a high fraction of esophageal cancer in China. Dissimilar distribution of several lifestyle factors, together with hereditary variations may be largely responsible for the incidence difference between areas.

Original language	English
Pages (from-to)	189-196
Journal	Cancer Letters
Volume	308
Issue number	2
DOIs	https://doi.org/10.1016/j.canlet.2011.05.003
Publication status	Published - 2011

Keywords

squamous-cell carcinoma
high-epidemic area
jiangsu province
confidence-intervals
alcohol-drinking
stomach-cancer
smoking
fractions
definition
tobacco

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.canlet.2011.05.003

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Wu, M., van 't Veer, P., Zhang, Z. F., Wang, X. S., Gu, X. P., Han, R. Q., Yang, J., Zhang, X. F., Liu, A. M., Kok, F. J., Kampman, E., & Zhao, J. K. (2011). A large proportion of esophageal cancer cases and the incidence difference between regions are attributable to lifestyle risk factors in China. Cancer Letters, 308(2), 189-196. https://doi.org/10.1016/j.canlet.2011.05.003

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title = "A large proportion of esophageal cancer cases and the incidence difference between regions are attributable to lifestyle risk factors in China",

abstract = "A population-based case-control study was conducted in a high-risk area (Dafeng) and a low-risk area (Ganyu) of Jiangsu province, China. In this analysis, the population attributable fraction (PAF) was calculated to quantify the etiology of risk factors; the relative attributable risk (RAR) was applied to explore how much of the incidence difference could be explained by variations in the distribution of risk factors. Results showed that unhealthy lifestyles accounted for a high fraction of esophageal cancer in China. Dissimilar distribution of several lifestyle factors, together with hereditary variations may be largely responsible for the incidence difference between areas.",

keywords = "squamous-cell carcinoma, high-epidemic area, jiangsu province, confidence-intervals, alcohol-drinking, stomach-cancer, smoking, fractions, definition, tobacco",

author = "M. Wu and {van 't Veer}, P. and Z.F. Zhang and X.S. Wang and X.P. Gu and R.Q. Han and J. Yang and X.F. Zhang and A.M. Liu and F.J. Kok and E. Kampman and J.K. Zhao",

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doi = "10.1016/j.canlet.2011.05.003",

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volume = "308",

pages = "189--196",

journal = "Cancer Letters",

issn = "0304-3835",

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TY - JOUR

T1 - A large proportion of esophageal cancer cases and the incidence difference between regions are attributable to lifestyle risk factors in China

AU - Wu, M.

AU - van 't Veer, P.

AU - Zhang, Z.F.

AU - Wang, X.S.

AU - Gu, X.P.

AU - Han, R.Q.

AU - Yang, J.

AU - Zhang, X.F.

AU - Liu, A.M.

AU - Kok, F.J.

AU - Kampman, E.

AU - Zhao, J.K.

PY - 2011

Y1 - 2011

N2 - A population-based case-control study was conducted in a high-risk area (Dafeng) and a low-risk area (Ganyu) of Jiangsu province, China. In this analysis, the population attributable fraction (PAF) was calculated to quantify the etiology of risk factors; the relative attributable risk (RAR) was applied to explore how much of the incidence difference could be explained by variations in the distribution of risk factors. Results showed that unhealthy lifestyles accounted for a high fraction of esophageal cancer in China. Dissimilar distribution of several lifestyle factors, together with hereditary variations may be largely responsible for the incidence difference between areas.

AB - A population-based case-control study was conducted in a high-risk area (Dafeng) and a low-risk area (Ganyu) of Jiangsu province, China. In this analysis, the population attributable fraction (PAF) was calculated to quantify the etiology of risk factors; the relative attributable risk (RAR) was applied to explore how much of the incidence difference could be explained by variations in the distribution of risk factors. Results showed that unhealthy lifestyles accounted for a high fraction of esophageal cancer in China. Dissimilar distribution of several lifestyle factors, together with hereditary variations may be largely responsible for the incidence difference between areas.

KW - squamous-cell carcinoma

KW - high-epidemic area

KW - jiangsu province

KW - confidence-intervals

KW - alcohol-drinking

KW - stomach-cancer

KW - smoking

KW - fractions

KW - definition

KW - tobacco

U2 - 10.1016/j.canlet.2011.05.003

DO - 10.1016/j.canlet.2011.05.003

M3 - Article

SN - 0304-3835

VL - 308

SP - 189

EP - 196

JO - Cancer Letters

JF - Cancer Letters

IS - 2

ER -

A large proportion of esophageal cancer cases and the incidence difference between regions are attributable to lifestyle risk factors in China

Abstract

Keywords

UN SDGs

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