A comparison of high‑throughput plasma NMR protocols for comparative untargeted metabolomics (Metabolomics

Nikolaos G. Bliziotis*, Udo F.H. Engelke, Ruud L.E.G. Aspers, Jasper Engel, Jaap Deinum, Henri J.L.M. Timmers, Ron A. Wevers, Leo A.J. Kluijtmans

*Corresponding author for this work

Research output: Contribution to journalComment/Letter to the editorAcademic

Abstract

Following publication of the original article, the authors would like to correct a sentence in the paragraph “1H-NMR spectra were recorded at 298 K…” under the heading “NMR experiments”. The sentence currently reads: “The LED pulse sequence had the form -RD-901-G1- 1801-G1-901-G2-T-901-G1-1801-G1-901-G2-t-901-acquire FID, where RD is a relaxation delay, 901 is a 901 RF pulse, G1 is the pulsed-field gradient that is applied to allow editing, 1801 is a 1801 RF pulse, G2 is a spoil gradient applied to remove unwanted magnetization components. The diffusion delay Δ is the time during which the molecules are allowed to diffuse—this is the period (901-G1-1801-G1- 901-G2-T-); and t is a delay to allow the longitudinal eddy currents caused within the sample to decay (Beckonert et al. 2007).” The sentence should read: “The LED pulse sequence had the form -RD-90°-G1- 180°-G1-90°-G2-T-90°-G1-180°-G1-90°-G2-t-90°-acquire FID, where RD is a relaxation delay, 90° is a 90° RF pulse, G1 is the pulsed-field gradient that is applied to allow editing, 180° is a 180° RF pulse, G2 is a spoil gradient applied to remove unwanted magnetization components. The diffusion delay ? is the time during which the molecules are allowed to diffuse—this is the period (90°-G1-180°-G1-90°-G2 T-); and t is a delay to allow the longitudinal eddy currents caused within the sample to decay (Beckonert et al. 2007).” This has been corrected with this erratum.

Original languageEnglish
Article number67
JournalMetabolomics
Volume16
Issue number6
DOIs
Publication statusPublished - Jun 2020

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    Bliziotis, N. G., Engelke, U. F. H., Aspers, R. L. E. G., Engel, J., Deinum, J., Timmers, H. J. L. M., ... Kluijtmans, L. A. J. (2020). A comparison of high‑throughput plasma NMR protocols for comparative untargeted metabolomics (Metabolomics. Metabolomics, 16(6), [67]. https://doi.org/10.1007/s11306-020-01688-w