A 67-Year-Old Male Patient With COVID-19 With Worsening Respiratory Function and Acute Kidney Failure

Max Melchers, Barbara Festen, Bianca M. den Dekker, Eline R.M. Mooren, Annelien L. van Binsbergen, Sjoerd H.W. van Bree, Moniek Heusinkveld, Roel Schellaars, Jochem B. Buil, Paul E. Verweij, Arthur R.H. van Zanten*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Abstract

Case Presentation: A 67-year-old obese man (BMI 38.0) with type 2 diabetes mellitus (DM), chronic atrial fibrillation, and chronic lymphocytic leukemia stage II, stable for 8 years after chemotherapy, and a history of smoking presented to the ED with progressive dyspnea and fever due to SARS-CoV-2 infection. He was admitted to a general ward and treated with dexamethasone (6 mg IV once daily) and oxygen. On day 3 of hospital admission, he became progressively hypoxemic and was admitted to the ICU for invasive mechanical ventilation. Dexamethasone treatment was continued, and a single dose of tocilizumab (800 mg) was administered. On day 9 of ICU admission, voriconazole treatment was initiated after tracheal white plaques at bronchoscopy, suggestive of invasive Aspergillus tracheobronchitis, were noticed. However, his medical situation dramatically deteriorated.

Original languageEnglish
Pages (from-to)e5-e11
JournalChest
Volume161
Issue number1
DOIs
Publication statusPublished - Jan 2022

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