TY - JOUR
T1 - A 67-Year-Old Male Patient With COVID-19 With Worsening Respiratory Function and Acute Kidney Failure
AU - Melchers, Max
AU - Festen, Barbara
AU - den Dekker, Bianca M.
AU - Mooren, Eline R.M.
AU - van Binsbergen, Annelien L.
AU - van Bree, Sjoerd H.W.
AU - Heusinkveld, Moniek
AU - Schellaars, Roel
AU - Buil, Jochem B.
AU - Verweij, Paul E.
AU - van Zanten, Arthur R.H.
PY - 2022/1
Y1 - 2022/1
N2 - Case Presentation: A 67-year-old obese man (BMI 38.0) with type 2 diabetes mellitus (DM), chronic atrial fibrillation, and chronic lymphocytic leukemia stage II, stable for 8 years after chemotherapy, and a history of smoking presented to the ED with progressive dyspnea and fever due to SARS-CoV-2 infection. He was admitted to a general ward and treated with dexamethasone (6 mg IV once daily) and oxygen. On day 3 of hospital admission, he became progressively hypoxemic and was admitted to the ICU for invasive mechanical ventilation. Dexamethasone treatment was continued, and a single dose of tocilizumab (800 mg) was administered. On day 9 of ICU admission, voriconazole treatment was initiated after tracheal white plaques at bronchoscopy, suggestive of invasive Aspergillus tracheobronchitis, were noticed. However, his medical situation dramatically deteriorated.
AB - Case Presentation: A 67-year-old obese man (BMI 38.0) with type 2 diabetes mellitus (DM), chronic atrial fibrillation, and chronic lymphocytic leukemia stage II, stable for 8 years after chemotherapy, and a history of smoking presented to the ED with progressive dyspnea and fever due to SARS-CoV-2 infection. He was admitted to a general ward and treated with dexamethasone (6 mg IV once daily) and oxygen. On day 3 of hospital admission, he became progressively hypoxemic and was admitted to the ICU for invasive mechanical ventilation. Dexamethasone treatment was continued, and a single dose of tocilizumab (800 mg) was administered. On day 9 of ICU admission, voriconazole treatment was initiated after tracheal white plaques at bronchoscopy, suggestive of invasive Aspergillus tracheobronchitis, were noticed. However, his medical situation dramatically deteriorated.
U2 - 10.1016/j.chest.2021.08.045
DO - 10.1016/j.chest.2021.08.045
M3 - Article
AN - SCOPUS:85122431256
SN - 0012-3692
VL - 161
SP - e5-e11
JO - Chest
JF - Chest
IS - 1
ER -