A 67-Year-Old Male Patient With COVID-19 With Worsening Respiratory Function and Acute Kidney Failure

Max Melchers; Barbara Festen; Bianca M. den Dekker; Eline R.M. Mooren; Annelien L. van Binsbergen; Sjoerd H.W. van Bree; Moniek Heusinkveld; Roel Schellaars; Jochem B. Buil; Paul E. Verweij; Arthur R.H. van Zanten

doi:10.1016/j.chest.2021.08.045

A 67-Year-Old Male Patient With COVID-19 With Worsening Respiratory Function and Acute Kidney Failure

Max Melchers, Barbara Festen, Bianca M. den Dekker, Eline R.M. Mooren, Annelien L. van Binsbergen, Sjoerd H.W. van Bree, Moniek Heusinkveld, Roel Schellaars, Jochem B. Buil, Paul E. Verweij, Arthur R.H. van Zanten^*

^*Corresponding author for this work

Nutritional Biology

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Case Presentation: A 67-year-old obese man (BMI 38.0) with type 2 diabetes mellitus (DM), chronic atrial fibrillation, and chronic lymphocytic leukemia stage II, stable for 8 years after chemotherapy, and a history of smoking presented to the ED with progressive dyspnea and fever due to SARS-CoV-2 infection. He was admitted to a general ward and treated with dexamethasone (6 mg IV once daily) and oxygen. On day 3 of hospital admission, he became progressively hypoxemic and was admitted to the ICU for invasive mechanical ventilation. Dexamethasone treatment was continued, and a single dose of tocilizumab (800 mg) was administered. On day 9 of ICU admission, voriconazole treatment was initiated after tracheal white plaques at bronchoscopy, suggestive of invasive Aspergillus tracheobronchitis, were noticed. However, his medical situation dramatically deteriorated.

Original language	English
Pages (from-to)	e5-e11
Journal	Chest
Volume	161
Issue number	1
DOIs	https://doi.org/10.1016/j.chest.2021.08.045
Publication status	Published - Jan 2022

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title = "A 67-Year-Old Male Patient With COVID-19 With Worsening Respiratory Function and Acute Kidney Failure",

abstract = "Case Presentation: A 67-year-old obese man (BMI 38.0) with type 2 diabetes mellitus (DM), chronic atrial fibrillation, and chronic lymphocytic leukemia stage II, stable for 8 years after chemotherapy, and a history of smoking presented to the ED with progressive dyspnea and fever due to SARS-CoV-2 infection. He was admitted to a general ward and treated with dexamethasone (6 mg IV once daily) and oxygen. On day 3 of hospital admission, he became progressively hypoxemic and was admitted to the ICU for invasive mechanical ventilation. Dexamethasone treatment was continued, and a single dose of tocilizumab (800 mg) was administered. On day 9 of ICU admission, voriconazole treatment was initiated after tracheal white plaques at bronchoscopy, suggestive of invasive Aspergillus tracheobronchitis, were noticed. However, his medical situation dramatically deteriorated.",

author = "Max Melchers and Barbara Festen and {den Dekker}, {Bianca M.} and Mooren, {Eline R.M.} and {van Binsbergen}, {Annelien L.} and {van Bree}, {Sjoerd H.W.} and Moniek Heusinkveld and Roel Schellaars and Buil, {Jochem B.} and Verweij, {Paul E.} and {van Zanten}, {Arthur R.H.}",

year = "2022",

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doi = "10.1016/j.chest.2021.08.045",

language = "English",

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T1 - A 67-Year-Old Male Patient With COVID-19 With Worsening Respiratory Function and Acute Kidney Failure

AU - Melchers, Max

AU - Festen, Barbara

AU - den Dekker, Bianca M.

AU - Mooren, Eline R.M.

AU - van Binsbergen, Annelien L.

AU - van Bree, Sjoerd H.W.

AU - Heusinkveld, Moniek

AU - Schellaars, Roel

AU - Buil, Jochem B.

AU - Verweij, Paul E.

AU - van Zanten, Arthur R.H.

PY - 2022/1

Y1 - 2022/1

N2 - Case Presentation: A 67-year-old obese man (BMI 38.0) with type 2 diabetes mellitus (DM), chronic atrial fibrillation, and chronic lymphocytic leukemia stage II, stable for 8 years after chemotherapy, and a history of smoking presented to the ED with progressive dyspnea and fever due to SARS-CoV-2 infection. He was admitted to a general ward and treated with dexamethasone (6 mg IV once daily) and oxygen. On day 3 of hospital admission, he became progressively hypoxemic and was admitted to the ICU for invasive mechanical ventilation. Dexamethasone treatment was continued, and a single dose of tocilizumab (800 mg) was administered. On day 9 of ICU admission, voriconazole treatment was initiated after tracheal white plaques at bronchoscopy, suggestive of invasive Aspergillus tracheobronchitis, were noticed. However, his medical situation dramatically deteriorated.

AB - Case Presentation: A 67-year-old obese man (BMI 38.0) with type 2 diabetes mellitus (DM), chronic atrial fibrillation, and chronic lymphocytic leukemia stage II, stable for 8 years after chemotherapy, and a history of smoking presented to the ED with progressive dyspnea and fever due to SARS-CoV-2 infection. He was admitted to a general ward and treated with dexamethasone (6 mg IV once daily) and oxygen. On day 3 of hospital admission, he became progressively hypoxemic and was admitted to the ICU for invasive mechanical ventilation. Dexamethasone treatment was continued, and a single dose of tocilizumab (800 mg) was administered. On day 9 of ICU admission, voriconazole treatment was initiated after tracheal white plaques at bronchoscopy, suggestive of invasive Aspergillus tracheobronchitis, were noticed. However, his medical situation dramatically deteriorated.

U2 - 10.1016/j.chest.2021.08.045

DO - 10.1016/j.chest.2021.08.045

M3 - Article

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VL - 161

SP - e5-e11

JO - Chest

JF - Chest

IS - 1

ER -

A 67-Year-Old Male Patient With COVID-19 With Worsening Respiratory Function and Acute Kidney Failure

Abstract

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