Neuromuscular electrical stimulation (NMES) and protein intake in the intensive care unit (ICU): combining muscle contractions and nutrition to prevent muscle wasting in ICU patients.

Critically ill ICU patients often experience significant muscle wasting, which increases the risk of death and lengthens the time it takes to rehabilitate. Physical inactivity, caused by mechanical ventilation and sedation, is believed to be an important contributor to muscle loss. Mimicking physical activity through electrical stimulation of the whole body, simultaneously with the intake of protein-rich food, may support the maintenance of muscle mass. In this project, I will combine studies in ventilated ICU patients and healthy volunteers, with the aim of preserving muscle mass and improving clinical outcomes for critically ill patients.