Methanol metabolism of sulfate reducing bacteria

Project: PhD

Project Details


Methanol is an excellent substrate for microbial growth in many different environments. Anaerobic methanol degradation is well studied in methanogens and acetogens. However, methanol is not a known common substrate for sulfate-reducing bacteria. Only a few sulfate reducers are described to be able to utilize methanol, which include some Gram-negative (Desulfovibrio) and Gram-positive (Desulfotomaculum) bacteria. Recently, we performed a proteomics study, which revealed that Desulfotomaculum kuznetsovii possesses two methanol-degrading pathways: involving a methyltransferase system and a methanol dehydrogenase. We aim to further describe these pathways and to study the methanol metabolism of other methanol-utilizing sulfate-reducing bacteria, including the isolation of novel anaerobes from different environments (including extreme environments). This research is also of practical importance as sulfate-reducing bacteria can be exploited in sulfur biotechnology to remove sulfur and metals from waste streams.
Effective start/end date1/05/19 → …


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