Mechanisms of toxicity of neonicotinoid insecticides towards aquatic arthropod species

The present work is carried out to extend our knowledge about the interspecies and intraspecies sensitivity differences for two insecticides, imidacloprid and flupyradifurone. By using the toxicokinetic-toxicodynamic models (TK-TD), the important role of biotransformation, the kinetic differences of chemicals and the intrinsic sensitivity differences of tested organisms will be determined.