Ecology from Farm to Fork Of microbial drug Resistance and Transmission

    Project: EU research project

    Project Details

    Description

    EFFORT studies the complex epidemiology and ecology of antimicrobial resistance and the interactions between bacterial communities, commensals and pathogens in animals, the food chain and the environment.This will be conducted by a combination of epidemiological and ecological studies using newly developed molecular and bio-informatics technologies. EFFORT will include an exposure assessment of humans from animal/environmental sources. The ecological studies on isolates will be verified by in vitro and in vivo studies. Moreover, real-life intervention studies will be conducted aiming at reducing the use of antimicrobials in veterinary practice. Focus will be on understanding the eco-epidemiology of antimicrobial resistance from animal origin and based on this, predicting and limiting the future evolution and exposure to humans of the most clinically important resistance by synthesising different sources of information in our prediction models. Through its results, the EFFORT research will provide scientific evidence and high quality data that will inform decision makers, the scientific community and other stakeholders about the consequences of AMR in the food chain, in relation to animal health and welfare, food safety and economic aspects. These results can be used to support political decisions and to prioritize risk management options along the food chain. The EFFORT consortium is made up of 20 partners from 10 European countries: Belgium, Bulgaria, Denmark, France, Germany, Italy, the Netherlands, Poland, Spain and Switzerland.
    The senior investigators leading this proposal bring together complementary strengths antimicrobial resistance, food safety, epidemiology of food borne pathogens and risk modelling, environmental epidemiology and microbial ecology, exposure assessment, veterinary microbiology, preventive molecular characterization of AMR, genetics and biology of DNA transfer mechanisms, whole genome sequencing for bacteria and economics of animal diseases
    AcronymEFFORT
    StatusFinished
    Effective start/end date1/12/1330/11/18

    Research Output

    Antimicrobial usage and resistance in companion animals: A cross-sectional study in three european countries

    Joosten, P., Ceccarelli, D., Odent, E., Sarrazin, S., Graveland, H., Van Gompel, L., Battisti, A., Caprioli, A., Franco, A., Wagenaar, J. A., Mevius, D. & Dewulf, J., 1 Feb 2020, In : Antibiotics. 9, 2, 87.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
  • Incompatibility and phylogenetic relationship of I-complex plasmids

    Rozwandowicz, M., Hordijk, J., Bossers, A., Zomer, A. L., Wagenaar, J. A., Mevius, D. J. & Brouwer, M. S. M., May 2020, In : Plasmid. 109, 102502.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
  • The relation between technical farm performance and antimicrobial use of broiler farms

    Roskam, J. L., Oude Lansink, A. G. J. M. & Saatkamp, H. W., Mar 2020, In : Poultry Science. 99, 3, p. 1349-1356 8 p.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access