COMREC is built on the hypothesis that the control of meiotic crossover (CO) frequency and distribution is dependent on the interplay between the biochemical processes of the recombination machinery, the programmed reorganisation of the chromosomes during meiotic progression and the organisation of the chromatin “landscape”. The PhD project “Bioinformatic analyses of meiotic recombination in tomato hybrids and related species” specifically focuses on a multidisciplinary approach to analyze (i) the genetic variation in recombination, (ii) CO sequence features and types, (iii) the frequency of recombination, and (iv) the synteny and structural homology involved in recombination cold and hot spots. The various types of sequence- and genome-topology data will be integrated to predict recombination “cold spots” and “hot spots”.
|Effective start/end date
|1/01/14 → 1/10/18