Antibioticum tolerantie als mogelijke indicator voor therapie falen (KB-37-003-067)

Project: LNV project

Project Details


Treating infections with antibiotics is not always effective. This means that during
treatment not all bacteria are killed by the antibiotic. This allows bacteria
grow again after a course of treatment is repeated and again for complaints and contagiousness
to assure. This also includes the notifiable infectious diseases, Brucella canis in dogs, Chlamydia
psittaci in birds and Mycobacterium bovis in cats. A possible explanation for this is tolerance:
During antibiotic pressure, some bacteria stop growing but remain alive. This
bacteria are also called tolerant bacteria. The presence of tolerance is also
associated with the development of antibiotic resistance. That is why we want to do this in this project
Brucella researchers can accept this under antibiotic pressure and whether this makes a contribution
contributes to resistance development. We also want to investigate which genes are responsible
are for adjustment to a tolerant state. This knowledge is necessary for correct and effective use
antibiotics in both humans and animals.
Effective start/end date1/01/2431/12/24


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