Research output per year
Research output per year
- 13 results
Search results
-
2020
Direct Visualization of Native CRISPR Target Search in Live Bacteria Reveals Cascade DNA Surveillance Mechanism
Vink, J. N. A., Martens, K. J. A., Vlot, M., McKenzie, R. E., Almendros, C., Estrada Bonilla, B., Brocken, D. J. W., Hohlbein, J. & Brouns, S. J. J., 2 Jan 2020, In: Molecular Cell. 77, 1, p. 39-50.e10Research output: Contribution to journal › Article › Academic › peer-review
Open Access36 Link opens in a new tab Citations (Scopus) -
Extracting Transition Rates in Particle Tracking Using Analytical Diffusion Distribution Analysis
Vink, J. N. A., Brouns, S. J. J. & Hohlbein, J., Nov 2020, In: Biophysical Journal. 119, 10, p. 1970-1983Research output: Contribution to journal › Article › Academic › peer-review
Open Access22 Link opens in a new tab Citations (Scopus) -
2019
Cas4-Cas1 fusions drive efficient PAM selection and control CRISPR adaptation
Almendros, C., Nobrega, F. L., McKenzie, R. E. & Brouns, S. J. J., 4 Jun 2019, In: Nucleic acids research. 47, 10, p. 5223-5230 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access38 Link opens in a new tab Citations (Scopus) -
Conserved motifs in the CRISPR leader sequence control spacer acquisition levels in Type I-D CRISPR-Cas systems
Kieper, S. N., Almendros, C. & Brouns, S. J. J., 1 Jun 2019, In: FEMS Microbiology Letters. 366, 11, fnz129.Research output: Contribution to journal › Article › Academic › peer-review
Open Access17 Link opens in a new tab Citations (Scopus) -
Harnessing type I CRISPR–Cas systems for genome engineering in human cells
Cameron, P., Coons, M. M., Klompe, S. E., Lied, A. M., Smith, S. C., Vidal, B., Donohoue, P. D., Rotstein, T., Kohrs, B. W., Nyer, D. B., Kennedy, R., Banh, L. M., Williams, C., Toh, M. S., Irby, M. J., Edwards, L. S., Lin, C. H., Owen, A. L. G., Künne, T. & van der Oost, J. & 7 others, , 18 Dec 2019, In: Nature Biotechnology. 37, p. 1471-1477Research output: Contribution to journal › Letter › Academic › peer-review
104 Link opens in a new tab Citations (Scopus) -
Molecular and Evolutionary Determinants of Bacteriophage Host Range
de Jonge, P. A., Nobrega, F. L., Brouns, S. J. J. & Dutilh, B. E., 2019, In: Trends in Microbiology. 27, 1, p. 51-63Research output: Contribution to journal › Article › Academic › peer-review
386 Link opens in a new tab Citations (Scopus) -
Using CAPTURE to detect spacer acquisition in native CRISPR arrays
McKenzie, R. E., Almendros, C., Vink, J. N. A. & Brouns, S. J. J., Mar 2019, In: Nature protocols. 14, 3, p. 976-990Research output: Contribution to journal › Article › Academic › peer-review
12 Link opens in a new tab Citations (Scopus) -
2018
Repetitive DNA Reeling by the Cascade-Cas3 Complex in Nucleotide Unwinding Steps
Loeff, L., Brouns, S. J. J. & Joo, C., 3 May 2018, In: Molecular Cell. 70, 3, p. 385-394Research output: Contribution to journal › Article › Academic › peer-review
Open Access52 Link opens in a new tab Citations (Scopus) -
Role of nucleotide identity in effective CRISPR target escape mutations
Künne, T., Zhu, Y., da Silva, F., Konstantinides, N., McKenzie, R. E., Jackson, R. N. & Brouns, S. J. J., 2 Nov 2018, In: Nucleic acids research. 46, 19, p. 10395-10404Research output: Contribution to journal › Article › Academic › peer-review
Open Access12 Link opens in a new tab Citations (Scopus) -
Targeting mechanisms of tailed bacteriophages
Nobrega, F. L., Vlot, M., de Jonge, P. A., Dreesens, L. L., Beaumont, H. J. E., Lavigne, R., Dutilh, B. E. & Brouns, S. J. J., 13 Aug 2018, In: Nature Reviews Microbiology. 16, p. 760–773Research output: Contribution to journal › Article › Academic › peer-review
529 Link opens in a new tab Citations (Scopus) -
2017
CRISPR-Cas: Adapting to change
Jackson, S. A., McKenzie, R. E., Fagerlund, R. D., Kieper, S. N., Fineran, P. C. & Brouns, S. J. J., 2017, In: Science. 356, 6333, eaal5056.Research output: Contribution to journal › Article › Academic › peer-review
361 Link opens in a new tab Citations (Scopus) -
2016
Cas3-Derived Target DNA Degradation Fragments Fuel Primed CRISPR Adaptation
Künne, T., Kieper, S. N., Bannenberg, J. W., Vogel, A., Miellet, W. R., Klein, M., Depken, M., Suarez-Diez, M. & Brouns, S. J. J., 2016, In: Molecular Cell. 63, 5, p. 852-864Research output: Contribution to journal › Article › Academic › peer-review
Open Access103 Link opens in a new tab Citations (Scopus) -
2015
CRISPR interference and priming varies with individual spacer sequences
Xue, C., Seetharam, A. S., Musharova, O., Severinov, K., Brouns, S. J. J., Severin, A. J. & Sashital, D. G., 2015, In: Nucleic acids research. 43, 22, p. 10831-10847Research output: Contribution to journal › Article › Academic › peer-review
Open Access83 Link opens in a new tab Citations (Scopus)