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A computer-aided platform to design and exploit non-ribosomal peptide synthetases for drug discovery

    Project: NWO project

    Project Details

    Description

    A computer-aided drug discovery platform to design and explore modular peptide synthetases

    Re-engineering known natural compounds has been a challenging but worthwhile goal, with applications in medicine, agriculture, and bio-sustainability. This research aims to develop new computational methods to enable re-design of microbial compounds by exploiting recent structural insights into protein function and leveraging vast genomic databases in an automated workflow.
    StatusFinished
    Effective start/end date1/02/2130/04/24

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