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Research Output 1989 2019

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Review article
2019
3 Citations (Scopus)

Biotechnology of health-promoting bacteria

Douillard, F. P. & de Vos, W. M., 12 Mar 2019, In : Biotechnology Advances. 37, 6, 107369.

Research output: Contribution to journalReview articleAcademicpeer-review

Biotechnology
Bacteria
Health
Probiotics
Functional Food

Reconstructing functional networks in the human intestinal tract using synthetic microbiomes

Shetty, S. A., Smidt, H. & de Vos, W. M., 1 Aug 2019, In : Current Opinion in Biotechnology. 58, p. 146-154

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Microbiota
Ecosystems
Ecosystem
Insurance Benefits
Ports and harbors
3 Citations (Scopus)

The Use of Defined Microbial Communities To Model Host-Microbe Interactions in the Human Gut

Elzinga, J., van der Oost, J., de Vos, W. M. & Smidt, H., 13 Mar 2019, In : Microbiology and Molecular Biology Reviews. 83, 2, p. 1-40

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Synbiotics
Organoids
Germ-Free Life
Microbiota
Probiotics
2018
6 Citations (Scopus)

Early life colonization of the human gut: microbes matter everywhere

Korpela, K. & de Vos, W. M., 1 Aug 2018, In : Current Opinion in Microbiology. 44, p. 70-78

Research output: Contribution to journalReview articleAcademicpeer-review

Microbiota
Mothers
Parturition
Bacteria
Child Development
3 Citations (Scopus)

Flux, impact, and fate of halogenated xenobiotic compounds in the gut

Atashgahi, S., Shetty, S. A., Smidt, H. & de Vos, W. M., 10 Jul 2018, In : Frontiers in Physiology. 9, JUL, 888.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Xenobiotics
Microbiota
Metagenomics
Pharmaceutical Preparations
Genes
2017
17 Citations (Scopus)

More than just a gut feeling: constraint-based genome-scale metabolic models for predicting functions of human intestinal microbes

van der Ark, K. C. H., van Heck, R. G. A., Martins Dos Santos, V. A. P., Belzer, C. & de Vos, W. M., 14 Jul 2017, In : Microbiome. 5, 1, p. 78

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Ecosystem
Emotions
Genome
Phenotype
Homeostasis
24 Citations (Scopus)

Safety of novel microbes for human consumption: Practical examples of assessment in the European Union

Brodmann, T., Endo, A., Gueimonde, M., Vinderola, G., Kneifel, W., de Vos, W. M., Salminen, S. & Gómez-Gallego, C., 2017, In : Frontiers in Microbiology. 8, 15 p., 1725.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
European Union
Safety
Food
Bacteria
Lactic Acid
73 Citations (Scopus)

The first microbial colonizers of the human gut: Composition, activities, and health implications of the infant gut microbiota

Milani, C., Duranti, S., Bottacini, F., Casey, E., Turroni, F., Mahony, J., Belzer, C., Palacio, S. D., Montes, S. A., Mancabelli, L., Lugli, G. A., Rodriguez, J. M., Bode, L., De Vos, W., Gueimonde, M., Margolles, A., Van Sinderen, D. & Ventura, M., 1 Dec 2017, In : Microbiology and Molecular Biology Reviews. 81, 4, e00036.

Research output: Contribution to journalReview articleAcademicpeer-review

Microbiota
Microbial Consortia
Health
Metagenomics
Functional Food
2016
50 Citations (Scopus)

Next Generation Prokaryotic Engineering: The CRISPR-Cas Toolkit

Mougiakos, I., Bosma, E. F., de Vos, W. M., van Kranenburg, R. & van der Oost, J., 2016, In : Trends in Biotechnology. 34, 7, p. 575-587

Research output: Contribution to journalReview articleAcademicpeer-review

Clustered Regularly Interspaced Short Palindromic Repeats
CRISPR-Cas Systems
Genes
Bacteria
Chemical Phenomena
2014
38 Citations (Scopus)

Effect of diet on the intestinal microbiota and its activity

Zoetendal, E. G. & de Vos, W. M., 2014, In : Current Opinion in Gastroenterology. 30, 2, p. 189-195

Research output: Contribution to journalReview articleAcademicpeer-review

Microbiota
Diet
Health
Gastrointestinal Microbiome
Feeding Behavior
93 Citations (Scopus)

Impact of Diet on Human Intestinal Microbiota and Health

Salonen, A. & de Vos, W. M., 2014, In : Annual Review of Food Science and Technology. 5, p. 239-262

Research output: Contribution to journalReview articleAcademicpeer-review

Microbiota
intestinal microorganisms
Diet
Health
diet
69 Citations (Scopus)

Metaproteomics of our microbiome - Developing insight in function and activity in man and model systems

Kolmeder, C. & de Vos, W. M., 2014, In : Journal of Proteomics. 97, p. 3-16

Research output: Contribution to journalReview articleAcademicpeer-review

Microbiota
Proteomics
Genes
Bacterial Genes
Body fluids
284 Citations (Scopus)

The first 1000 cultured species of the human gastrointestinal microbiota

Rajilic-Stojanovic, M. & de Vos, W. M., 2014, In : FEMS Microbiology Reviews. 38, 5, p. 996-1047

Research output: Contribution to journalReview articleAcademicpeer-review

Gastrointestinal Tract
Metagenomics
Archaea
Health
Eukaryota
2013
33 Citations (Scopus)

Contribution of the Intestinal Microbiota to Human Health: From Birth to 100 Years of Age

Cheng, J., Palva, A. M., de Vos, W. M. & Satokari, R., 2013, In : Current Topics in Microbiology and Immunology. 358, p. 323-346

Research output: Contribution to journalReview articleAcademicpeer-review

Microbiota
Parturition
Health
Multiple Birth Offspring
Symbiosis
41 Citations (Scopus)

Fame and future of faecal transplantations - developing next-generation therapies with synthetic microbiomes

de Vos, W. M., 2013, In : Microbial Biotechnology. 6, 4, p. 316-325

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Microbiota
Tissue Donors
Therapeutics
Fecal Microbiota Transplantation
Gastrointestinal Microbiome
41 Citations (Scopus)

Human intestinal metagenomics: state of the art and future

Blottière, H. M., de Vos, W. M., Ehrlich, S. D. & Doré, J., 2013, In : Current Opinion in Microbiology. 16, 3, p. 232-239

Research output: Contribution to journalReview articleAcademicpeer-review

Metagenomics
Health
Gastrointestinal Microbiome
12 Citations (Scopus)

Obesity, non-alcoholic fatty liver disease, and atherothrombosis: a role for the intestinal microbiota?

Knaapen, M., Kootte, R. S., Zoetendal, E. G., de Vos, W. M., Dallinga-Thie, G. M., Levi, M., Stroes, E. S. & Nieuwdorp, M., 2013, In : Clinical Microbiology and Infection. 19, 4, p. 331-337

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Obesity
Hemostatics
Routine Diagnostic Tests
Causality
Communicable Diseases
16 Citations (Scopus)

Potential of proton-pumping rhodopsins: engineering photosystems into microorganisms

Claassens, N. J. H. P., Volpers, M., Martins Dos Santos, V. A. P., van der Oost, J. & de Vos, W. M., 2013, In : Trends in Biotechnology. 31, 11, p. 633-642

Research output: Contribution to journalReview articleAcademicpeer-review

Rhodopsin
Microorganisms
Protons
Light
Microbial Rhodopsins
51 Citations (Scopus)

The intestinal microbiota and host immune interactions in the critically ill

Schuijt, T. J., van der Poll, T., de Vos, W. M. & Wiersinga, W. J., 2013, In : Trends in Microbiology. 21, 5, p. 221-229

Research output: Contribution to journalReview articleAcademicpeer-review

Critical Illness
Health
Critical Care
Gastrointestinal Tract
Immune System
251 Citations (Scopus)

Therapeutic potential of fecal microbiota transplantation

Smits, L. P., Bouter, K. E. C., de Vos, W. M., Borody, T. J. & Nieuwdorp, M., 2013, In : Gastroenterology. 145, 5, p. 946-953

Research output: Contribution to journalReview articleAcademicpeer-review

Microbiota
Inflammatory Bowel Diseases
Clostridium Infections
Disease Resistance
Idiopathic Thrombocytopenic Purpura
25 Citations (Scopus)

Towards metagenome-scale models for industrial applications-the case of Lactic Acid Bacteria

Branco Dos Santos, F., de Vos, W. M. & Teusink, B., 2013, In : Current Opinion in Biotechnology. 24, 2, p. 200-206

Research output: Contribution to journalReview articleAcademicpeer-review

Metagenome
Lactic acid
Industrial applications
Lactic Acid
Bacteria
2012
35 Citations (Scopus)

Early-life gut microbiota under physiological and pathological conditions : the central role of combined meta-omics-based approaches

Del Chierico, F., Vernocchi, P., Bonizzi, L. & de Vos, W. M., 2012, In : Journal of Proteomics. 75, 15, p. 4580-4587

Research output: Contribution to journalReview articleAcademicpeer-review

Microbiology
Pediatrics
Pathogens
Ecosystems
Aging of materials
213 Citations (Scopus)

Microbes inside—from diversity to function: the case of Akkermansia

Belzer, C. & de Vos, W. M., 2012, In : ISME Journal. 6, 8, p. 1449-1458

Research output: Contribution to journalReview articleAcademicpeer-review

intestinal microorganisms
microorganisms
Ecosystem
Germ-Free Life
health and disease
190 Citations (Scopus)

Role of the intestinal microbiome in health and disease: from correlation to causation

de Vos, W. M. & Vos, E. A., 2012, In : Nutrition Reviews. 70, suppl. 1, p. S45-S56

Research output: Contribution to journalReview articleAcademicpeer-review

Causality
Microbiota
Health
Technology
Gastrointestinal Microbiome
142 Citations (Scopus)

The function of our microbiota: who is out there and what do they do?

Ottman, N. A., Smidt, H., de Vos, W. M. & Belzer, C., 2012, In : Frontiers in Cellular and Infection Microbiology. 2, 11 p., 104.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Microbiota
Metagenome
Metagenomics
Microbial Genes
Infant Formula
167 Citations (Scopus)

The therapeutic potential of manipulating gut microbiota in obesity and type 2 diabetes mellitus

Kootte, R. S., Vrieze, A., Holleman, F., Zoetendal, E. G., de Vos, W. M., Groen, A. K., Hoekstra, J. B. & Nieuwdorp, M., 2012, In : Diabetes, Obesity & Metabolism. 14, 2, p. 112-120

Research output: Contribution to journalReview articleAcademicpeer-review

Type 2 Diabetes Mellitus
Obesity
Prebiotics
Volatile Fatty Acids
Microbiota
73 Citations (Scopus)

Where bio meets nano: The many uses for nanoporous aluminium oxide in biotechnology

Ingham, C. J., ter Maat, J. & de Vos, W. M., 2012, In : Biotechnology Advances. 30, 5, p. 1089-1099

Research output: Contribution to journalReview articleAcademicpeer-review

Aluminum Oxide
Biotechnology
Nanopores
Aluminum
Oxides
2011
289 Citations (Scopus)

Intestinal microbiota in human health and disease: the impact of probiotics

Gerritsen, J., Smidt, H., Rijkers, G. T. & de Vos, W. M., 2011, In : Genes & Nutrition. 6, 3, p. 209-240

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Probiotics
Health
Dysbiosis
Intestinal Diseases
Gastrointestinal Tract
2010
87 Citations (Scopus)

Exploiting the ecogenomics toolbox for environmental diagnostics of organohalide-respiring bacteria

Maphosa, F., de Vos, W. M. & Smidt, H., 2010, In : Trends in Biotechnology. 28, 6, p. 308-316

Research output: Contribution to journalReview articleAcademicpeer-review

Environmental Biodegradation
Bioremediation
Bacteria
Organic pollutants
Biodiversity
150 Citations (Scopus)

Gastrointestinal microbiota in irritable bowel syndrome: present state and perspectives

Salonen, A., de Vos, W. M. & Palva, A., 2010, In : Microbiology. 156, p. 3205-3215

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Irritable Bowel Syndrome
Microbiota
Gastrointestinal Microbiome
Dysbiosis
Gastrointestinal Diseases
43 Citations (Scopus)

Systems biology of the gut: the interplay of food, microbiota and host at the mucosal interface

Martins Dos Santos, V. A. P., Müller, M. R. & de Vos, W. M., 2010, In : Current Opinion in Biotechnology. 21, 4, p. 539-550

Research output: Contribution to journalReview articleAcademicpeer-review

Systems Biology
Microbiota
Animals
Genes
Food
177 Citations (Scopus)

The environment within: how gut microbiota may influence metabolism and body composition

Vrieze, A., Holleman, F., Zoetendal, E. G., de Vos, W. M., Hoekstra, J. B. & Nieuwdorp, M., 2010, In : Diabetologia. 53, 4, p. 606-613

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Body Composition
Obesity
Diet
Butyrates
Vascular Diseases
69 Citations (Scopus)

The little bacteria that can: diversity, genomics and ecophysiology of 'Dehalococcoides' spp. in contaminated environments

Tas, N., van Eekert, M. H. A., de Vos, W. M. & Smidt, H., 2010, In : Microbial Biotechnology. 3, 4, p. 389-402

Research output: Contribution to journalReview articleAcademicpeer-review

Dechlorination
Genomics
Bacteria
Genes
Microbiology
2008
407 Citations (Scopus)

High-throughput diversity and functionality analysis of the gastrointestinal tract microbiota

Zoetendal, E. G., Rajilic-Stojanovic, M. & de Vos, W. M., 2008, In : Gut. 57, p. 1605-1615

Research output: Contribution to journalReview articleAcademicpeer-review

Gastrointestinal Tract
Technology
Small Ribosome Subunits
Metagenomics
Ribosomal RNA
2007
324 Citations (Scopus)

Diversity of the human gastrointestinal tract microbiota revisited

Rajilic-Stojanovic, M., Smidt, H. & de Vos, W. M., 2007, In : Environmental Microbiology. 9, 9, p. 2125-2136

Research output: Contribution to journalReview articleAcademicpeer-review

gastrointestinal system
Gastrointestinal Tract
RNA
Ribosomal RNA
phylogenetics
57 Citations (Scopus)

Making sense of quorum sensing in lactobacilli: a special focus on Lactobacillus plantarum WCFS1

Sturme, M. H. J., Francke, C., Siezen, R., de Vos, W. M. & Kleerebezem, M., 2007, In : Microbiology. 153, p. 3939-3947

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Lactobacillus plantarum
Quorum Sensing
Lactobacillus
Peptides
Genes
80 Citations (Scopus)

Microbial communities in the human small intestine - coupling diversity to metagenomics

Booijink, C. C. G. M., Zoetendal, E. G., Kleerebezem, M. & de Vos, W. M., 2007, In : Future Microbiology. 2, p. 285-295

Research output: Contribution to journalReview articleAcademicpeer-review

Metagenomics
Small Intestine
Gastrointestinal Tract
Physiological Phenomena
Food
2006
265 Citations (Scopus)

A microbial world within us

Zoetendal, E. G., Vaughan, E. E. & de Vos, W. M., 2006, In : Molecular Microbiology. 59, 6, p. 1639-1650

Research output: Contribution to journalReview articleAcademicpeer-review

Gastrointestinal Tract
Health
Genotype
129 Citations (Scopus)

Beyond diversity: functional microbiomics of the human colon

Egert, M. G. G., de Graaf, A., Smidt, H., de Vos, W. M. & Venema, K., 2006, In : Trends in Microbiology. 14, 2, p. 86-91

Research output: Contribution to journalReview articleAcademicpeer-review

Colon
Intestinal Diseases
Health Promotion
Fermentation
Health
23 Citations (Scopus)

Nutridynamics--studying the dynamics of food components in products and in the consumer

de Vos, W. M., Castenmiller, J. J. M., Hamer, R. J. & Brummer, R. J., 2006, In : Current Opinion in Biotechnology. 17, 2, p. 217-225

Research output: Contribution to journalReview articleAcademicpeer-review

Food
Food technology
Nutrigenomics
Food Handling
Food Technology
2005
17 Citations (Scopus)

Discovering novel biology by in silico archaeology

Ettema, T. J. G., de Vos, W. M. & van der Oost, J., 2005, In : Nature Reviews Microbiology. 3, 11, p. 859-869

Research output: Contribution to journalReview articleAcademicpeer-review

Archaeology
Archaea
Computer Simulation
Archaeal Genome
Genomics
110 Citations (Scopus)

Diversity, vitality and activities of intestinal lactic acid bacteria and bifidobacteria assessed by molecular approaches

Vaughan, E. E., Heilig, G. H. J., Ben-Amor, K. & de Vos, W. M., 2005, In : FEMS Microbiology Reviews. 29, 3, p. 477-490

Research output: Contribution to journalReview articleAcademicpeer-review

Bifidobacterium
Lactic Acid
Bacteria
Functional Food
Probiotics
29 Citations (Scopus)

Functional ingredient production: application of global metabolic models

Smid, E. J., Molenaar, D., Hugenholtz, J., de Vos, W. M. & Teusink, B., 2005, In : Current Opinion in Biotechnology. 16, 2, p. 190-197

Research output: Contribution to journalReview articleAcademicpeer-review

Genome
Metabolic Engineering
Intuition
Genetic Models
Biotechnology
100 Citations (Scopus)

Prebiotics and other microbial substrates for gut functionality

Ouwehand, A. C., Derrien, M. M. N., de Vos, W. M., Tiihonen, K. & Rautonen, N., 2005, In : Current Opinion in Biotechnology. 16, 2, p. 212-217

Research output: Contribution to journalReview articleAcademicpeer-review

Prebiotics
Intestines
Substrates
Nutrients
Modulation
252 Citations (Scopus)

Probiotic and other functional microbes: from markets to mechanisms

Saxelin, M., Tynkkynen, S., Matilla-Sandholm, T. & de Vos, W. M., 2005, In : Current Opinion in Biotechnology. 16, 2, p. 204-211

Research output: Contribution to journalReview articleAcademicpeer-review

Probiotics
Bacteria
Bifidobacterium
Immune system
Lactobacillus
2004
352 Citations (Scopus)

Anaerobic microbial dehalogenation

Smidt, H. & de Vos, W. M., 2004, In : Annual Review of Microbiology. 58, p. 43-73

Research output: Contribution to journalReview articleAcademicpeer-review

Halogenated Hydrocarbons
Biological Phenomena
Xenobiotics
Enzymes
Electron Transport
106 Citations (Scopus)

Engineering metabolic highways in Lactococci and other lactic acid bacteria

de Vos, W. M. & Hugenholtz, J., 2004, In : Trends in Biotechnology. 22, 2, p. 72-79

Research output: Contribution to journalReview articleAcademicpeer-review

Lactococcus
Metabolic engineering
Metabolic Engineering
Lactic acid
Lactic Acid
47 Citations (Scopus)

Post-genomics of lactic acid bacteria and other food-grade bacteria to discover gut functionality

de Vos, W. M., Bron, P. A. & Kleerebezem, M., 2004, In : Current Opinion in Biotechnology. 15, 2, p. 86-93

Research output: Contribution to journalReview articleAcademicpeer-review

Functional Food
Lactic acid
Genomics
Lactic Acid
Bacteria
2003
185 Citations (Scopus)

The Lrp family of transcriptional regulators

Brinkman, A. B., Ettema, T. J. G., de Vos, W. M. & van der Oost, J., 2003, In : Molecular Microbiology. 48, 2, p. 287-294

Research output: Contribution to journalReview articleAcademicpeer-review

Binding Sites
Leucine-Responsive Regulatory Protein
DNA
Pyrococcus furiosus
Genome
166 Citations (Scopus)

Unique features of glycolysis in Archaea

Verhees, C. H., Kengen, S. W. M., Tuininga, J. E., Schut, G. J., Adams, M. W. W., de Vos, W. M. & van der Oost, J., 2003, In : Biochemical Journal. 375, p. 231-246

Research output: Contribution to journalReview articleAcademicpeer-review

Archaea
Glycolysis
Enzymes
Bacteria
Genomics