If you made any changes in Pure these will be visible here soon.

Research Output 1989 2019

2019
3 Citations (Scopus)

A Bifidobacterial pilus-associated protein promotes colonic epithelial proliferation

O'Connell Motherway, M., Houston, A., O'Callaghan, G., Reunanen, J., O'Brien, F., O'Driscoll, T., Casey, P. G., de Vos, W. M., van Sinderen, D. & Shanahan, F., Jan 2019, In : Molecular Microbiology. 111, 1, p. 287-301

Research output: Contribution to journalArticleAcademicpeer-review

Cell Proliferation
Fimbriae Proteins
Aptitude
Bifidobacterium
Human Development
2 Citations (Scopus)

Akkermansia muciniphila ameliorates the age-related decline in colonic mucus thickness and attenuates immune activation in accelerated aging Ercc1 -/Δ7 mice

van der Lugt, B., van Beek, A. A., Aalvink, S., Meijer, B., Sovran, B., Vermeij, W. P., Brandt, R. M. C., de Vos, W. M., Savelkoul, H. F. J., Steegenga, W. T. & Belzer, C., 8 Mar 2019, In : Immunity and Ageing. 16, 1, 6.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Mucus
B-Lymphocytes
B-Lymphoid Precursor Cells
Transcriptome
Anti-Inflammatory Agents

Akkermansia muciniphila Exerts Lipid-Lowering and Immunomodulatory Effects without Affecting Neointima Formation in Hyperlipidemic APOE*3-Leiden.CETP Mice

Katiraei, S., de Vries, M. R., Costain, A. H., Thiem, K., Hoving, L. R., van Diepen, J. A., Smits, H. H., Bouter, K. E., Rensen, P. C. N., Quax, P. H. A., Nieuwdorp, M., Netea, M. G., de Vos, W. M., Cani, P. D., Belzer, C., van Dijk, K. W., Berbée, J. F. P. & van Harmelen, V., 6 Aug 2019, In : Molecular Nutrition and Food Research. 1900732.

Research output: Contribution to journalArticleAcademicpeer-review

Neointima
Lipids
lipid metabolism
B-lymphocytes
mice

Allogenic Faecal Microbiota Transfer Induces Immune-Related Gene Sets in the Colon Mucosa of Patients with Irritable Bowel Syndrome

Holster, S., Hooiveld, G. J., Repsilber, D., de Vos, W. M., Brummer, R. J. & König, J., 8 Oct 2019, In : Biomolecules. 9, 10, 586.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Irritable Bowel Syndrome
Microbiota
Colon
Mucous Membrane
Genes
1 Citation (Scopus)

Anaerobic Degradation of N-ϵ-Carboxymethyllysine, a Major Glycation End-Product, by Human Intestinal Bacteria

Bui, T. P. N., Troise, A. D., Fogliano, V. & De Vos, W. M., 12 Jun 2019, In : Journal of Agricultural and Food Chemistry. 67, 23, p. 6594-6602 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
glycation
intestinal microorganisms
anaerobic conditions
Bacteria
Degradation

Bicistronic Design-Based Continuous and High-Level Membrane Protein Production in Escherichia coli

Claassens, N. J., Finger-Bou, M., Scholten, B., Muis, F., De Groot, J. J., De Gier, J. W., De Vos, W. M. & Van Der Oost, J., 17 Jun 2019, In : ACS synthetic biology. 8, 7, p. 1685-1690 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Escherichia coli
Membrane Proteins
Proteins
Membranes
Cell Engineering
3 Citations (Scopus)

Biotechnology of health-promoting bacteria

Douillard, F. P. & de Vos, W. M., 1 Nov 2019, In : Biotechnology Advances. 37, 6, 107369.

Research output: Contribution to journalReview articleAcademicpeer-review

Biotechnology
Bacteria
Health
Probiotics
Functional Food
6 Citations (Scopus)

Bowel Biofilms: Tipping Points between a Healthy and Compromised Gut?

Tytgat, H. L. P., Nobrega, F. L., van der Oost, J. & de Vos, W. M., Jan 2019, In : Trends in Microbiology. 27, 1, p. 17-25

Research output: Contribution to journalArticleAcademicpeer-review

Biofilms
Mucous Membrane
Intestinal Diseases
Health
Colonic Neoplasms

Cohort profile: Finnish Health and Early Life Microbiota (HELMi) longitudinal birth cohort

Korpela, K., Dikareva, E., Hanski, E., Kolho, K. L., De Vos, W. M. & Salonen, A., 1 Jun 2019, In : BMJ Open. 9, 6, e028500.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Microbiota
Parturition
Health
Life Style
Parents

Development of omics-based protocols for the microbiological characterization of multi-strain formulations marketed as probiotics: the case of VSL#3

Mora, D., Filardi, R., Arioli, S., Boeren, S., Aalvink, S. & de Vos, W. M., Nov 2019, In : Microbial Biotechnology. 12, 6, p. 1371-1386

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Probiotics
Galactosidases
Single-Cell Analysis
High-Throughput Nucleotide Sequencing
Metagenomics

Double kill : the DNase and RNase activity of CRISPR-Cas type III systems

Zhu, Y., 2019, Wageningen: Wageningen University. 184 p.

Research output: Thesisinternal PhD, WUAcademic

Open Access

Dynamics of the Gut Microbiota in Children Receiving Selective or Total Gut Decontamination Treatment during Hematopoietic Stem Cell Transplantation

Bekker, V., Zwittink, R. D., Knetsch, C. W., Sanders, I. M. J. G., Berghuis, D., Heidt, P. J., Vossen, J. M. J. J., de Vos, W. M., Belzer, C., Bredius, R. G. M., van‘t Hof, P. J., Lankester, A. C. & Kuijper, E. J., Jun 2019, In : Biology of Blood and Marrow Transplantation. 25, 6, p. 1164-1171

Research output: Contribution to journalArticleAcademicpeer-review

Decontamination
Hematopoietic Stem Cell Transplantation
Microbiota
Therapeutics
Bacteroides
1 Citation (Scopus)

Enhanced nutrient supply and intestinal microbiota development in very low birth weight infants

Blakstad, E. W., Korpela, K., Lee, S., Nakstad, B., Moltu, S. J., Strømmen, K., Rønnestad, A. E., Brække, K., Iversen, P. O., de Vos, W. M. & Drevon, C. A., 14 May 2019, In : Pediatric Research. 86, p. 323-332

Research output: Contribution to journalArticleAcademicpeer-review

Very Low Birth Weight Infant
Food
Microbiota
Bifidobacterium
Gestational Age

Fecal matter for prevention or treatment of autoimmune diseases

Nieuwdorp, M. & de Vos, W. M., 6 Sep 2019, Patent No. WO2019168401, Priority date 20 Jul 2018

Research output: PatentOther research output

Open Access
MicroRNAs
Duodenum
Feces
Bacteriophages
Autoimmune Diseases
3 Citations (Scopus)

Gender-specific associations between saliva microbiota and body size

Raju, S. C., Lagström, S., Ellonen, P., De Vos, W. M., Eriksson, J. G., Weiderpass, E. & Rounge, T. B., 10 Apr 2019, In : Frontiers in Microbiology. 10, APR, 00767.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Microbiota
Body Size
Saliva
Weights and Measures
Selenomonas
10 Citations (Scopus)

Intestinal epithelial N-acylphosphatidylethanolamine phospholipase D links dietary fat to metabolic adaptations in obesity and steatosis

Everard, A., Plovier, H., Rastelli, M., Van Hul, M., de Wouters d’Oplinter, A., Geurts, L., Druart, C., Robine, S., Delzenne, N. M., Muccioli, G. G., de Vos, W. M., Luquet, S., Flamand, N., Di Marzo, V. & Cani, P. D., 1 Dec 2019, In : Nature Communications. 10, 1, 457.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
obesity
Phospholipase D
Dietary Fats
fats
mice
5 Citations (Scopus)

Long-term impact of oral vancomycin, ciprofloxacin and metronidazole on the gut microbiota in healthy humans

Haak, B. W., Lankelma, J. M., Hugenholtz, F., Belzer, C., de Vos, W. M. & Wiersinga, W. J., 1 Mar 2019, In : The Journal of antimicrobial chemotherapy. 74, 3, p. 782-786 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Metronidazole
Vancomycin
Ciprofloxacin
Anti-Bacterial Agents
Microbiota

Metabolic improvement in obese patients after duodenal–jejunal exclusion is associated with intestinal microbiota composition changes

de Jonge, C., Fuentes, S., Zoetendal, E. G., Bouvy, N. D., Nelissen, R., Buurman, W. A., Greve, J. W., de Vos, W. M. & Rensen, S. S., 14 Feb 2019, In : International Journal of Obesity.

Research output: Contribution to journalArticleAcademicpeer-review

Type 2 Diabetes Mellitus
Obesity
Microbiota
Small Intestine
Veillonella

Molecular ecology of the yet uncultured bacterial Ct85-cluster in the mammalian gut

Hynönen, U., Zoetendal, E. G., Virtala, A. M. K., Shetty, S., Hasan, S., Jakava-Viljanen, M., de Vos, W. M. & Palva, A., 25 Sep 2019, In : Anaerobe. 102104.

Research output: Contribution to journalArticleAcademicpeer-review

Irritable Bowel Syndrome
Ecology
rRNA Genes
Feces
Cohort Studies

Reconstructing functional networks in the human intestinal tract using synthetic microbiomes

Shetty, S. A., Smidt, H. & de Vos, W. M., 1 Aug 2019, In : Current Opinion in Biotechnology. 58, p. 146-154

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Microbiota
Ecosystems
Ecosystem
Insurance Benefits
Ports and harbors
17 Citations (Scopus)

Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study

Depommier, C., Everard, A., Druart, C., Plovier, H., Van Hul, M., Vieira-Silva, S., Falony, G., Raes, J., Maiter, D., Delzenne, N. M., de Barsy, M., Loumaye, A., Hermans, M. P., Thissen, J. P., de Vos, W. M. & Cani, P. D., 1 Jul 2019, In : Nature Medicine. 25, 7, p. 1096-1103 8 p.

Research output: Contribution to journalLetterAcademicpeer-review

Volunteers
Placebos
Insulin
Medical problems
Type 2 Diabetes Mellitus

The development of early life gut microbiota in health and allergic disease

Wopereis, H., 2019, Wageningen: Wageningen University. 184 p.

Research output: Thesisinternal PhD, WUAcademic

5 Citations (Scopus)

The Effect of Allogenic Versus Autologous Fecal Microbiota Transfer on Symptoms, Visceral Perception and Fecal and Mucosal Microbiota in Irritable Bowel Syndrome: A Randomized Controlled Study

Holster, S., Lindqvist, C. M., Repsilber, D., Salonen, A., de Vos, W. M., König, J. & Brummer, R. J., 15 Apr 2019, In : Clinical and Translational Gastroenterology. 10, 4, p. e00034

Research output: Contribution to journalArticleAcademicpeer-review

Irritable Bowel Syndrome
Microbiota
Colonoscopy
Mucous Membrane
Tissue Donors
2 Citations (Scopus)

The Effect of Psyllium Husk on Intestinal Microbiota in Constipated Patients and Healthy Controls

Jalanka, J., Major, G., Murray, K., Singh, G., Nowak, A., Kurtz, C., Silos-Santiago, I., Johnston, J. M., de Vos, W. M. & Spiller, R., 20 Jan 2019, In : International Journal of Molecular Sciences. 20, 2, 433.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Psyllium
Water
Microbiota
transit
Veillonella

The Gut Microbiota in the First Decade of Life

Derrien, M., Alvarez, A. S. & de Vos, W. M., 29 Aug 2019, In : Trends in Microbiology.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Microbiota
Age Groups
Diet
Gastrointestinal Microbiome
Population
6 Citations (Scopus)

The Use of Defined Microbial Communities To Model Host-Microbe Interactions in the Human Gut

Elzinga, J., van der Oost, J., de Vos, W. M. & Smidt, H., 13 Mar 2019, In : Microbiology and Molecular Biology Reviews. 83, 2, p. 1-40

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Synbiotics
Organoids
Germ-Free Life
Microbiota
Probiotics

Universal membrane-labeling combined with expression of Katushka far-red fluorescent protein enables non-invasive dynamic and longitudinal quantitative 3D dual-color fluorescent imaging of multiple bacterial strains in mouse intestine

Peñate-Medina, O., Tower, R. J., Peñate-Medina, T., Will, O., Saris, P. E. J., Suojanen, J., Sorsa, T., Huuskonen, L., Hiippala, K., Satokari, R., Glüer, C. C., de Vos, W. M. & Reunanen, J., 18 Jul 2019, In : BMC Microbiology. 19, 1, 1 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Intestines
Color
Bacteria
Membranes
Microbiota

Zooming in: from multi-omics to single function in hyperthermophilic archaeon Sulfolobus solfataricus

Sierocinski, P., 2019, Wageningen: Wageningen University. 209 p.

Research output: Thesisinternal PhD, WUAcademic

Open Access
2018
46 Citations (Scopus)

Akkermansia muciniphila induces gut microbiota remodelling and controls islet autoimmunity in NOD mice

Hänninen, A., Toivonen, R., Pöysti, S., Belzer, C., Plovier, H., Ouwerkerk, J. P., Emani, R., Cani, P. D. & de Vos, W. M., 1 Aug 2018, In : Gut. 67, 8, p. 1445-1453

Research output: Contribution to journalArticleAcademicpeer-review

Inbred NOD Mouse
Autoimmunity
Microbiota
Incidence
Type 1 Diabetes Mellitus
9 Citations (Scopus)

Comparative genomic analysis of the multispecies probiotic-marketed product VSL#3

Douillard, F. P., Mora, D., Eijlander, R. T., Wels, M. & De Vos, W. M., 1 Feb 2018, In : PLoS ONE. 13, 2, e0192452.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Probiotics
Lactobacillus helveticus
Streptococcus thermophilus
probiotics
Bifidobacterium
8 Citations (Scopus)
Open Access
Mucins
Expectorants
Acetyl Coenzyme A
Butyrates
Operon
10 Citations (Scopus)

Early life colonization of the human gut: microbes matter everywhere

Korpela, K. & de Vos, W. M., 1 Aug 2018, In : Current Opinion in Microbiology. 44, p. 70-78

Research output: Contribution to journalReview articleAcademicpeer-review

Microbiota
Mothers
Parturition
Bacteria
Child Development
15 Citations (Scopus)

Effect of vegan fecal microbiota transplantation on carnitine- and choline-derived trimethylamine-N-oxide production and vascular inflammation in patients with metabolic syndrome

Smits, L. P., Kootte, R. S., Levin, E., Prodan, A., Fuentes, S., Zoetendal, E. G., Wang, Z., Levison, B. S., Cleophas, M. C. P., Kemper, E. M., Dallinga-Thie, G. M., Groen, A. K., Joosten, L. A. B., Netea, M. G., Stroes, E. S. G., de Vos, W. M., Hazen, S. L. & Nieuwdorp, M., 1 Apr 2018, In : Journal of the American Heart Association. 7, 7, e008342.

Research output: Contribution to journalArticleAcademicpeer-review

Carnitine
Choline
Blood Vessels
Inflammation
Tissue Donors
1 Citation (Scopus)
Eubacterium
Eubacteria
metabolism
Bacteria
bacterium
20 Citations (Scopus)

Fecal microbiota transplantation against intestinal colonization by extended spectrum beta-lactamase producing Enterobacteriaceae: A proof of principle study ISRCTN48328635 ISRCTN

Singh, R., de Groot, P. F., Geerlings, S. E., Hodiamont, C. J., Belzer, C., ten Berge, I. J. M., de Vos, W. M., Bemelman, F. J. & Nieuwdorp, M., 22 Mar 2018, In : BMC Research Notes. 11, 1, 190.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Transplants
Enterobacteriaceae
beta-Lactamases
Microbiota
Clostridium
3 Citations (Scopus)

Flux, impact, and fate of halogenated xenobiotic compounds in the gut

Atashgahi, S., Shetty, S. A., Smidt, H. & de Vos, W. M., 10 Jul 2018, In : Frontiers in Physiology. 9, JUL, 888.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Xenobiotics
Microbiota
Metagenomics
Pharmaceutical Preparations
Genes
6 Citations (Scopus)

Fucosylated oligosaccharides in mother’s milk alleviate the effects of caesarean birth on infant gut microbiota

Korpela, K., Salonen, A., Hickman, B., Kunz, C., Sprenger, N., Kukkonen, K., Savilahti, E., Kuitunen, M. & de Vos, W. M., 13 Sep 2018, In : Scientific Reports. 8, 1, 13757.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Oligosaccharides
Milk
Mothers
Parturition
Human Milk
20 Citations (Scopus)

Intestinal microbiota development and gestational age in preterm neonates

Korpela, K., Blakstad, E. W., Moltu, S. J., Strømmen, K., Nakstad, B., Rønnestad, A. E., Brække, K., Iversen, P. O., Drevon, C. A. & de Vos, W., 6 Feb 2018, In : Scientific Reports. 8, 1, 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Microbiota
Gestational Age
Newborn Infant
Premature Infants
Enterococcus
5 Citations (Scopus)

Intestinal Microbiota in Hirschsprung Disease

Neuvonen, M. I., Korpela, K., Kyrklund, K., Salonen, A., de Vos, W., Rintala, R. J. & Pakarinen, M. P., Nov 2018, In : Journal of Pediatric Gastroenterology and Nutrition. 67, 5, p. 594-600

Research output: Contribution to journalArticleAcademicpeer-review

Hirschsprung Disease
Enterocolitis
Microbiota
Leukocyte L1 Antigen Complex
Lactase

Metabolic characterization and viable delivery of Akkermansia muciniphila for its future application

van der Ark, K., 2018, Wageningen: Wageningen University. 236 p.

Research output: Thesisinternal PhD, WUAcademic

Open Access
genetically engineered microorganisms
bacteria
emulsions
oxygen
development aid
3 Citations (Scopus)

Model-driven design of a minimal medium for Akkermansia muciniphila confirms mucus adaptation

van der Ark, K. C. H., Aalvink, S., Suarez-Diez, M., Schaap, P. J., de Vos, W. M. & Belzer, C., 1 May 2018, In : Microbial Biotechnology. 11, 3, p. 476-485

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Mucins
Mucus
Phosphates
Glucosamine
Fructose
38 Citations (Scopus)

Mouse models for human intestinal microbiota research: a critical evaluation

Hugenholtz, F. & de Vos, W. M., Jan 2018, In : Cellular and Molecular Life Sciences. 75, 1, p. 149-160

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Research
Microbiota
Comparative Physiology
Bacterial Genes
Metagenomics
2 Citations (Scopus)

Organic acid production from potato starch waste fermentation by rumen microbial communities from Dutch and Thai dairy cows

Palakawong Na Ayudthaya, S., Van De Weijer, A. H. P., Van Gelder, A. H., Stams, A. J. M., De Vos, W. M. & Plugge, C. M., 25 Jan 2018, In : Biotechnology for Biofuels. 11, 1, 13.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Dairies
Organic acids
Rumen
Solanum tuberosum
Starch

Organic acid production from starchy waste by gut derived microorganisms

Palakawong Na Ayudthaya, S., 2018, Wageningen: Wageningen University. 219 p.

Research output: Thesisinternal PhD, WUAcademic

Open Access
15 Citations (Scopus)

Probiotic supplementation restores normal microbiota composition and function in antibiotic-treated and in caesarean-born infants

Korpela, K., Salonen, A., Vepsäläinen, O., Suomalainen, M., Kolmeder, C., Varjosalo, M., Miettinen, S., Kukkonen, K., Savilahti, E., Kuitunen, M. & de Vos, W. M., 16 Oct 2018, In : Microbiome. 6, 1, 182.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Microbiota
Probiotics
Anti-Bacterial Agents
Lactobacillus rhamnosus
Parturition
1 Citation (Scopus)

Publisher Correction: Enterotypes in the landscape of gut microbial community composition

Costea, P. I., Hildebrand, F., Arumugam, M., Bäckhed, F., Blaser, M. J., Bushman, F. D., de Vos, W. M., Ehrlich, S. D., Fraser, C. M., Hattori, M., Huttenhower, C., Jeffery, I. B., Knights, D., Lewis, J. D., Ley, R. E., Ochman, H., O’Toole, P. W., Quince, C., Relman, D. A., Shanahan, F. & 9 othersSunagawa, S., Wang, J., Weinstock, G. M., Wu, G. D., Zeller, G., Zhao, L., Raes, J., Knight, R. & Bork, P., 13 Feb 2018, In : Nature Microbiology. 3, 388.

Research output: Contribution to journalComment/Letter to the editorAcademic

Names
2 Citations (Scopus)
Open Access
Eubacterium hallii
Eubacterium
Comb and Wattles
Butyrates
Propionates
5 Citations (Scopus)

Reproducibility and repeatability of six high-throughput 16S rDNA sequencing protocols for microbiota profiling

Raju, S. C., Lagström, S., Ellonen, P., de Vos, W. M., Eriksson, J. G., Weiderpass, E. & Rounge, T. B., 1 Apr 2018, In : Journal of Microbiological Methods. 147, p. 76-86

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Microbiota
Ribosomal DNA
Saliva
Epidemiologic Studies
Technology

Romboutsia hominis sp. nov., the first human gut-derived representative of the genus Romboutsia, isolated from ileostoma effluent

Gerritsen, J., Umanets, A., Staneva, I., Hornung, B., Ritari, J., Paulin, L., Rijkers, G. T., de Vos, W. M. & Smidt, H., 1 Nov 2018, In : International Journal of Systematic and Evolutionary Microbiology. 68, 11, p. 3479-3486

Research output: Contribution to journalArticleAcademicpeer-review

effluents
digestive system
effluent
DNA
fatty acid