1989 …2020

Research output per year

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Research Output

2020

Akkermansia muciniphila reduces Porphyromonas gingivalis-induced inflammation and periodontal bone destruction

Huck, O., Mulhall, H., Rubin, G., Kizelnik, Z., Iyer, R., Perpich, J. D., Haque, N., Cani, P. D., de Vos, W. M. & Amar, S., Feb 2020, In : Journal of Clinical Periodontology. 47, 2, p. 202-212

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Antibiotics in early life associate with specific gut microbiota signatures in a prospective longitudinal infant cohort

Korpela, K., Salonen, A., Saxen, H., Nikkonen, A., Peltola, V., Jaakkola, T., de Vos, W. & Kolho, K. L., 18 Jan 2020, In : Pediatric Research.

Research output: Contribution to journalArticleAcademicpeer-review

Bridging Bacteria and the Gut: Functional Aspects of Type IV Pili

Ligthart, K., Belzer, C., de Vos, W. M. & Tytgat, H. L. P., May 2020, In : Trends in Microbiology. 28, 5, 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Effect of fructans, prebiotics and fibres on the human gut microbiome assessed by 16S rRNA-based approaches: a review

Swanson, K. S., de Vos, W. M., Martens, E. C., Gilbert, J. A., Menon, R. S., Soto-Vaca, A., Hautvast, J., Meyer, P. D., Borewicz, K., Vaughan, E. E. & Slavin, J. L., 27 Mar 2020, In : Beneficial Microbes. 11, 2, p. 101-129 29 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Intestinimonas-like bacteria are important butyrate producers that utilize Nε-fructosyllysine and lysine in formula-fed infants and adults

Bui, T. P. N., Troise, A. D., Nijsse, B., Roviello, G. N., Fogliano, V. & de Vos, W. M., Jul 2020, In : Journal of Functional Foods. 70, 103974.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Mediterranean diet intervention alters the gut microbiome in older people reducing frailty and improving health status: The NU-AGE 1-year dietary intervention across five European countries

Ghosh, T. S., Rampelli, S., Jeffery, I. B., Santoro, A., Neto, M., Capri, M., Giampieri, E., Jennings, A., Candela, M., Turroni, S., Zoetendal, E. G., Hermes, G. D. A., Elodie, C., Brugere, C. M., Pujos-Guillot, E., Berendsen, A. M., De Groot, L. C. P. G. M., Feskins, E. J. M., Kaluza, J., Pietruszka, B. & 10 others, Bielak, M. J., Comte, B., Maijo-Ferre, M., Nicoletti, C., de Vos, W. M., Fairweather-Tait, S., Cassidy, A., Brigidi, P., Franceschi, C. & O'Toole, P. W., Mar 2020, In : Gut. 319654.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
7 Citations (Scopus)

Molecular ecology of the yet uncultured bacterial Ct85-cluster in the mammalian gut

Hynönen, U., Zoetendal, E. G., Virtala, A. M. K., Shetty, S., Hasan, S., Jakava-Viljanen, M., de Vos, W. M. & Palva, A., Apr 2020, In : Anaerobe. 62, 102104.

Research output: Contribution to journalArticleAcademicpeer-review

Pasteurized Akkermansia muciniphila increases whole-body energy expenditure and fecal energy excretion in diet-induced obese mice

Depommier, C., Van Hul, M., Everard, A., Delzenne, N. M., de Vos, W. M. & Cani, P. D., 13 Mar 2020, In : Gut Microbes. 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2 Citations (Scopus)

Pasteurized Akkermansia muciniphila protects from fat mass gain but not from bone loss

Lawenius, L., Scheffler, J. M., Gustafsson, K. L., Henning, P., Nilsson, K. H., Colldén, H., Islander, U., Plovier, H., Cani, P. D., de Vos, W. M., Ohlsson, C. & Sjögren, K., Apr 2020, In : American Journal of Physiology. Endocrinology and Metabolism. 318, 4, p. E480-E491

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
3 Citations (Scopus)

Treatment with Anaerobutyricum soehngenii: a pilot study of safety and dose–response effects on glucose metabolism in human subjects with metabolic syndrome

Gilijamse, P. W., Hartstra, A. V., Levin, E., Wortelboer, K., Serlie, M. J., Ackermans, M. T., Herrema, H., Nederveen, A. J., Imangaliyev, S., Aalvink, S., Sommer, M., Levels, H., Stroes, E. S. G., Groen, A. K., Kemper, M., de Vos, W. M., Nieuwdorp, M. & Prodan, A., 27 Mar 2020, In : npj Biofilms and Microbiomes. 6, 1, 16.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2019

A Bifidobacterial pilus-associated protein promotes colonic epithelial proliferation

O'Connell Motherway, M., Houston, A., O'Callaghan, G., Reunanen, J., O'Brien, F., O'Driscoll, T., Casey, P. G., de Vos, W. M., van Sinderen, D. & Shanahan, F., Jan 2019, In : Molecular Microbiology. 111, 1, p. 287-301

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

Akkermansia muciniphila ameliorates the age-related decline in colonic mucus thickness and attenuates immune activation in accelerated aging Ercc1 -/Δ7 mice

van der Lugt, B., van Beek, A. A., Aalvink, S., Meijer, B., Sovran, B., Vermeij, W. P., Brandt, R. M. C., de Vos, W. M., Savelkoul, H. F. J., Steegenga, W. T. & Belzer, C., 8 Mar 2019, In : Immunity and Ageing. 16, 1, 6.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
8 Citations (Scopus)

Akkermansia muciniphila Exerts Lipid-Lowering and Immunomodulatory Effects without Affecting Neointima Formation in Hyperlipidemic APOE*3-Leiden.CETP Mice

Katiraei, S., de Vries, M. R., Costain, A. H., Thiem, K., Hoving, L. R., van Diepen, J. A., Smits, H. H., Bouter, K. E., Rensen, P. C. N., Quax, P. H. A., Nieuwdorp, M., Netea, M. G., de Vos, W. M., Cani, P. D., Belzer, C., van Dijk, K. W., Berbée, J. F. P. & van Harmelen, V., 6 Aug 2019, In : Molecular Nutrition and Food Research. 1900732.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2 Citations (Scopus)

Allogenic Faecal Microbiota Transfer Induces Immune-Related Gene Sets in the Colon Mucosa of Patients with Irritable Bowel Syndrome

Holster, S., Hooiveld, G. J., Repsilber, D., de Vos, W. M., Brummer, R. J. & König, J., 8 Oct 2019, In : Biomolecules. 9, 10, 586.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Anaerobic Degradation of N-ϵ-Carboxymethyllysine, a Major Glycation End-Product, by Human Intestinal Bacteria

Bui, T. P. N., Troise, A. D., Fogliano, V. & De Vos, W. M., 12 Jun 2019, In : Journal of Agricultural and Food Chemistry. 67, 23, p. 6594-6602 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
5 Citations (Scopus)

Bicistronic Design-Based Continuous and High-Level Membrane Protein Production in Escherichia coli

Claassens, N. J., Finger-Bou, M., Scholten, B., Muis, F., De Groot, J. J., De Gier, J. W., De Vos, W. M. & Van Der Oost, J., 17 Jun 2019, In : ACS synthetic biology. 8, 7, p. 1685-1690 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2 Citations (Scopus)

Biotechnology of health-promoting bacteria

Douillard, F. P. & de Vos, W. M., 1 Nov 2019, In : Biotechnology Advances. 37, 6, 107369.

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Bowel Biofilms: Tipping Points between a Healthy and Compromised Gut?

Tytgat, H. L. P., Nobrega, F. L., van der Oost, J. & de Vos, W. M., Jan 2019, In : Trends in Microbiology. 27, 1, p. 17-25

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)

Cohort profile: Finnish Health and Early Life Microbiota (HELMi) longitudinal birth cohort

Korpela, K., Dikareva, E., Hanski, E., Kolho, K. L., De Vos, W. M. & Salonen, A., 1 Jun 2019, In : BMJ Open. 9, 6, e028500.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2 Citations (Scopus)

Development of omics-based protocols for the microbiological characterization of multi-strain formulations marketed as probiotics: the case of VSL#3

Mora, D., Filardi, R., Arioli, S., Boeren, S., Aalvink, S. & de Vos, W. M., Nov 2019, In : Microbial Biotechnology. 12, 6, p. 1371-1386

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2 Citations (Scopus)

Dynamics of the Gut Microbiota in Children Receiving Selective or Total Gut Decontamination Treatment during Hematopoietic Stem Cell Transplantation

Bekker, V., Zwittink, R. D., Knetsch, C. W., Sanders, I. M. J. G., Berghuis, D., Heidt, P. J., Vossen, J. M. J. J., de Vos, W. M., Belzer, C., Bredius, R. G. M., van‘t Hof, P. J., Lankester, A. C. & Kuijper, E. J., Jun 2019, In : Biology of Blood and Marrow Transplantation. 25, 6, p. 1164-1171

Research output: Contribution to journalArticleAcademicpeer-review

Enhanced nutrient supply and intestinal microbiota development in very low birth weight infants

Blakstad, E. W., Korpela, K., Lee, S., Nakstad, B., Moltu, S. J., Strømmen, K., Rønnestad, A. E., Brække, K., Iversen, P. O., de Vos, W. M. & Drevon, C. A., 14 May 2019, In : Pediatric Research. 86, p. 323-332

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Fecal matter for prevention or treatment of autoimmune diseases

Nieuwdorp, M. & de Vos, W. M., 6 Sep 2019, Patent No. WO2019168401, Priority date 20 Jul 2018

Research output: PatentOther research output

Open Access

Gender-specific associations between saliva microbiota and body size

Raju, S. C., Lagström, S., Ellonen, P., De Vos, W. M., Eriksson, J. G., Weiderpass, E. & Rounge, T. B., 10 Apr 2019, In : Frontiers in Microbiology. 10, APR, 00767.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
6 Citations (Scopus)

Intestinal epithelial N-acylphosphatidylethanolamine phospholipase D links dietary fat to metabolic adaptations in obesity and steatosis

Everard, A., Plovier, H., Rastelli, M., Van Hul, M., de Wouters d’Oplinter, A., Geurts, L., Druart, C., Robine, S., Delzenne, N. M., Muccioli, G. G., de Vos, W. M., Luquet, S., Flamand, N., Di Marzo, V. & Cani, P. D., 1 Dec 2019, In : Nature Communications. 10, 1, 457.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
18 Citations (Scopus)

Long-term impact of oral vancomycin, ciprofloxacin and metronidazole on the gut microbiota in healthy humans

Haak, B. W., Lankelma, J. M., Hugenholtz, F., Belzer, C., de Vos, W. M. & Wiersinga, W. J., 1 Mar 2019, In : The Journal of antimicrobial chemotherapy. 74, 3, p. 782-786 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)

Metabolic improvement in obese patients after duodenal–jejunal exclusion is associated with intestinal microbiota composition changes

de Jonge, C., Fuentes, S., Zoetendal, E. G., Bouvy, N. D., Nelissen, R., Buurman, W. A., Greve, J. W., de Vos, W. M. & Rensen, S. S., 14 Feb 2019, In : International Journal of Obesity. 43, p. 2509–2517

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
1 Citation (Scopus)

Reconstructing functional networks in the human intestinal tract using synthetic microbiomes

Shetty, S. A., Smidt, H. & de Vos, W. M., 1 Aug 2019, In : Current Opinion in Biotechnology. 58, p. 146-154

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study

Depommier, C., Everard, A., Druart, C., Plovier, H., Van Hul, M., Vieira-Silva, S., Falony, G., Raes, J., Maiter, D., Delzenne, N. M., de Barsy, M., Loumaye, A., Hermans, M. P., Thissen, J. P., de Vos, W. M. & Cani, P. D., 1 Jul 2019, In : Nature Medicine. 25, 7, p. 1096-1103 8 p.

Research output: Contribution to journalLetterAcademicpeer-review

112 Citations (Scopus)

The Effect of Allogenic Versus Autologous Fecal Microbiota Transfer on Symptoms, Visceral Perception and Fecal and Mucosal Microbiota in Irritable Bowel Syndrome: A Randomized Controlled Study

Holster, S., Lindqvist, C. M., Repsilber, D., Salonen, A., de Vos, W. M., König, J. & Brummer, R. J., 15 Apr 2019, In : Clinical and Translational Gastroenterology. 10, 4, p. e00034

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
13 Citations (Scopus)

The Effect of Psyllium Husk on Intestinal Microbiota in Constipated Patients and Healthy Controls

Jalanka, J., Major, G., Murray, K., Singh, G., Nowak, A., Kurtz, C., Silos-Santiago, I., Johnston, J. M., de Vos, W. M. & Spiller, R., 20 Jan 2019, In : International Journal of Molecular Sciences. 20, 2, 433.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
9 Citations (Scopus)

The Gut Microbiota in the First Decade of Life

Derrien, M., Alvarez, A. S. & de Vos, W. M., Dec 2019, In : Trends in Microbiology. 27, 12, p. 997-1010

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
12 Citations (Scopus)

The Use of Defined Microbial Communities To Model Host-Microbe Interactions in the Human Gut

Elzinga, J., van der Oost, J., de Vos, W. M. & Smidt, H., 13 Mar 2019, In : Microbiology and Molecular Biology Reviews. 83, 2, p. 1-40

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
11 Citations (Scopus)

Universal membrane-labeling combined with expression of Katushka far-red fluorescent protein enables non-invasive dynamic and longitudinal quantitative 3D dual-color fluorescent imaging of multiple bacterial strains in mouse intestine

Peñate-Medina, O., Tower, R. J., Peñate-Medina, T., Will, O., Saris, P. E. J., Suojanen, J., Sorsa, T., Huuskonen, L., Hiippala, K., Satokari, R., Glüer, C. C., de Vos, W. M. & Reunanen, J., 18 Jul 2019, In : BMC Microbiology. 19, 1, 167.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2018

Akkermansia muciniphila induces gut microbiota remodelling and controls islet autoimmunity in NOD mice

Hänninen, A., Toivonen, R., Pöysti, S., Belzer, C., Plovier, H., Ouwerkerk, J. P., Emani, R., Cani, P. D. & de Vos, W. M., 1 Aug 2018, In : Gut. 67, 8, p. 1445-1453

Research output: Contribution to journalArticleAcademicpeer-review

77 Citations (Scopus)

Comparative genomic analysis of the multispecies probiotic-marketed product VSL#3

Douillard, F. P., Mora, D., Eijlander, R. T., Wels, M. & De Vos, W. M., 1 Feb 2018, In : PLoS ONE. 13, 2, e0192452.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
11 Citations (Scopus)
Open Access
14 Citations (Scopus)

Early life colonization of the human gut: microbes matter everywhere

Korpela, K. & de Vos, W. M., 1 Aug 2018, In : Current Opinion in Microbiology. 44, p. 70-78

Research output: Contribution to journalArticleAcademicpeer-review

21 Citations (Scopus)

Effect of vegan fecal microbiota transplantation on carnitine- and choline-derived trimethylamine-N-oxide production and vascular inflammation in patients with metabolic syndrome

Smits, L. P., Kootte, R. S., Levin, E., Prodan, A., Fuentes, S., Zoetendal, E. G., Wang, Z., Levison, B. S., Cleophas, M. C. P., Kemper, E. M., Dallinga-Thie, G. M., Groen, A. K., Joosten, L. A. B., Netea, M. G., Stroes, E. S. G., de Vos, W. M., Hazen, S. L. & Nieuwdorp, M., 1 Apr 2018, In : Journal of the American Heart Association. 7, 7, e008342.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
26 Citations (Scopus)
1 Citation (Scopus)

Fecal microbiota transplantation against intestinal colonization by extended spectrum beta-lactamase producing Enterobacteriaceae: A proof of principle study ISRCTN48328635 ISRCTN

Singh, R., de Groot, P. F., Geerlings, S. E., Hodiamont, C. J., Belzer, C., ten Berge, I. J. M., de Vos, W. M., Bemelman, F. J. & Nieuwdorp, M., 22 Mar 2018, In : BMC Research Notes. 11, 1, 190.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
30 Citations (Scopus)

Flux, impact, and fate of halogenated xenobiotic compounds in the gut

Atashgahi, S., Shetty, S. A., Smidt, H. & de Vos, W. M., 10 Jul 2018, In : Frontiers in Physiology. 9, JUL, 888.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
8 Citations (Scopus)

Fucosylated oligosaccharides in mother’s milk alleviate the effects of caesarean birth on infant gut microbiota

Korpela, K., Salonen, A., Hickman, B., Kunz, C., Sprenger, N., Kukkonen, K., Savilahti, E., Kuitunen, M. & de Vos, W. M., 13 Sep 2018, In : Scientific Reports. 8, 1, 13757.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
12 Citations (Scopus)

Intestinal microbiota development and gestational age in preterm neonates

Korpela, K., Blakstad, E. W., Moltu, S. J., Strømmen, K., Nakstad, B., Rønnestad, A. E., Brække, K., Iversen, P. O., Drevon, C. A. & de Vos, W., 6 Feb 2018, In : Scientific Reports. 8, 1, 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
31 Citations (Scopus)

Intestinal Microbiota in Hirschsprung Disease

Neuvonen, M. I., Korpela, K., Kyrklund, K., Salonen, A., de Vos, W., Rintala, R. J. & Pakarinen, M. P., Nov 2018, In : Journal of Pediatric Gastroenterology and Nutrition. 67, 5, p. 594-600

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Model-driven design of a minimal medium for Akkermansia muciniphila confirms mucus adaptation

van der Ark, K. C. H., Aalvink, S., Suarez-Diez, M., Schaap, P. J., de Vos, W. M. & Belzer, C., 1 May 2018, In : Microbial Biotechnology. 11, 3, p. 476-485

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
8 Citations (Scopus)

Mouse models for human intestinal microbiota research: a critical evaluation

Hugenholtz, F. & de Vos, W. M., Jan 2018, In : Cellular and Molecular Life Sciences. 75, 1, p. 149-160

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
67 Citations (Scopus)

Organic acid production from potato starch waste fermentation by rumen microbial communities from Dutch and Thai dairy cows

Palakawong Na Ayudthaya, S., Van De Weijer, A. H. P., Van Gelder, A. H., Stams, A. J. M., De Vos, W. M. & Plugge, C. M., 25 Jan 2018, In : Biotechnology for Biofuels. 11, 1, 13.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
6 Citations (Scopus)

Probiotic supplementation restores normal microbiota composition and function in antibiotic-treated and in caesarean-born infants

Korpela, K., Salonen, A., Vepsäläinen, O., Suomalainen, M., Kolmeder, C., Varjosalo, M., Miettinen, S., Kukkonen, K., Savilahti, E., Kuitunen, M. & de Vos, W. M., 16 Oct 2018, In : Microbiome. 6, 1, 182.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
30 Citations (Scopus)