20162020
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Research Output 2017 2020

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Article
2020

Good guide, bad guide: spacer sequence-dependent cleavage efficiency of Cas12a

Creutzburg, S. C. A., Wu, W., Mohanraju, P., Swartjes, T., Alkan, F., Gorodkin, J., Staals, R. H. J. & van der Oost, J., 28 Jan 2020, In : Nucleic acids research. gkz1240.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Base Pairing
Nucleic Acid Repetitive Sequences
Clustered Regularly Interspaced Short Palindromic Repeats
DNA Repair
Plasmids
2018
23 Citations (Scopus)

Genome editing by natural and engineered CRISPR-associated nucleases

Wu, W. Y., Lebbink, J. H. G., Kanaar, R., Geijsen, N. & van der Oost, J., 1 Jul 2018, In : Nature Chemical Biology. 14, 7, p. 642-651

Research output: Contribution to journalArticleAcademicpeer-review

Clustered Regularly Interspaced Short Palindromic Repeats
Peptides
Research
Gene Editing
2017
240 Citations (Scopus)

Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array

Zetsche, B., Heidenreich, M., Mohanraju, P., Fedorova, I., Kneppers, J., Degennaro, E. M., Winblad, N., Choudhury, S. R., Abudayyeh, O. O., Wu, W. Y. & van der Oost, J., 2017, In : Nature Biotechnology. 35, 1, p. 31-34

Research output: Contribution to journalArticleAcademicpeer-review

Clustered Regularly Interspaced Short Palindromic Repeats
RNA
Genes
Brain
Cells