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Research Output 1997 2019

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2019

Aspergillus niger citrate exporter revealed by comparison of two alternative citrate producing conditions

Odoni, D. I., Vazquez-Vilar, M., van Gaal, M. P., Schonewille, T., Martins Dos Santos, V. A. P., Tamayo-Ramos, J. A., Suarez-Diez, M. & Schaap, P. J., 1 Apr 2019, In : FEMS Microbiology Letters. 366, 7, fnz071.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Aspergillus niger
Citric Acid
Computational Biology
Saccharomyces cerevisiae
Arginine
1 Citation (Scopus)

Cofactors revisited – Predicting the impact of flavoprotein-related diseases on a genome scale

Wegrzyn, A. B., Stolle, S., Rienksma, R. A., Martins dos Santos, V. A. P., Bakker, B. M. & Suarez-Diez, M., 1 Feb 2019, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1865, 2, p. 360-370

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Flavoproteins
Biomarkers
Genome
Multiple Acyl Coenzyme A Dehydrogenase Deficiency
Flavins

Distant Non-Obvious Mutations Influence the Activity of a Hyperthermophilic Pyrococcusfuriosus Phosphoglucose Isomerase

Subramanian, K., Mitusińska, K., Raedts, J., Almourfi, F., Joosten, H. J., Hendriks, S., Sedelnikova, S. E., Kengen, S. W. M., Hagen, W. R., Góra, A., Martins Dos Santos, V. A. P., Baker, P. J., van der Oost, J. & Schaap, P. J., 31 May 2019, In : Biomolecules. 9, 6

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Glucose-6-Phosphate Isomerase
Protein Engineering
Metals
Glucose-6-Phosphate
Mutation

Macrophage-Specific NF-κB Activation Dynamics Can Segregate Inflammatory Bowel Disease Patients

Papoutsopoulou, S., Burkitt, M. D., Bergey, F., England, H., Hough, R., Schmidt, L., Spiller, D. G., White, M. H. R., Paszek, P., Jackson, D. A., Martins Dos Santos, V. A. P., Sellge, G., Pritchard, D. M., Campbell, B. J., Müller, W. & Probert, C. S., 11 Sep 2019, In : Frontiers in Immunology. 10, 11 p., 2168.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Inflammatory Bowel Diseases
Macrophages
Crohn Disease
Luciferases
Cytokines
Open Access
Host-Pathogen Interactions
Mycobacterium tuberculosis
Pharmaceutical Preparations
Metabolome
arginine glutamate

Patient’s characteristics and outcomes in necrotising soft-tissue infections: results from a Scandinavian, multicentre, prospective cohort study

Madsen, M. B., Skrede, S., Perner, A., Arnell, P., Nekludov, M., Bruun, T., Karlsson, Y., Hansen, M. B., Polzik, P., Hedetoft, M., Rosén, A., Saccenti, E., Bergey, F., Martins Dos Santos, V. A. P., Norrby-teglund, A. & Hyldegaard, O., Sep 2019, In : Intensive Care Medicine. 45, 9, p. 1241-1251

Research output: Contribution to journalArticleAcademicpeer-review

The diurnal transcriptional landscape of the microalga Tetradesmus obliquus

Carreres, B. M., Mitsue León-Saiki, G., Schaap, P. J., Remmers, I. M., van der Veen, D., Martins dos Santos, V. A. P., Wijffels, R. H., Martens, D. E. & Suarez-Diez, M., 1 Jun 2019, In : Algal Research. 40, 101477.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Tetradesmus
starch
photoperiod
process energy
scotophase
2018
Open Access
Enterocytes
Fatty Acids
Lipids
Dietary Carbohydrates
Mitochondrial Proteins

DMPy: a Python package for automated mathematical model construction of large-scale metabolic systems

Smith, R. W., van Rosmalen, R. P., Martins dos Santos, V. A. P. & Fleck, C., 19 Jun 2018, In : BMC Systems Biology. 12, 72.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Boidae
Python
Metabolic Networks and Pathways
Theoretical Models
Mathematical Model

Genome sequence of two members of the chloroaromatic-degrading MT community: Pseudomonas reinekei MT1 and Achromobacter xylosoxidans MT3

Gutierrez-Urrutia, I., Miossec, M. J., Valenzuela, S. L., Meneses, C., Martins dos Santos, V. A. P., Castro-Nallar, E. & Poblete-Castro, I., 10 Jun 2018, In : Journal of Biotechnology. 275, p. 13-16

Research output: Contribution to journalArticleAcademicpeer-review

Achromobacter denitrificans
Pseudomonas
Genes
Genome
Open Reading Frames
2 Citations (Scopus)

Modeling the Metabolic State of Mycobacterium tuberculosis Upon Infection

Rienksma, R. A., Schaap, P. J., Martins Dos Santos, V. A. P. & Suarez-Diez, M., 3 Aug 2018, In : Frontiers in Cellular and Infection Microbiology. 8, 264.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Mycobacterium tuberculosis
Biomass
Infection
Growth
Mycobacterium Infections
7 Citations (Scopus)

Modulating D-amino acid oxidase (DAAO) substrate specificity through facilitated solvent access

Subramanian, K., Góra, A., Spruijt, R., Mitusińska, K., Suarez-Diez, M., Martins Dos Santos, V. & Schaap, P. J., 1 Jan 2018, In : PLoS ONE. 13, 6, e0198990.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
D-Amino-Acid Oxidase
substrate specificity
Substrate Specificity
amino acids
Substrates
7 Citations (Scopus)

Necrotizing soft tissue infections - a multicentre, prospective observational study (INFECT): Protocol and statistical analysis plan

Madsen, M. B., Skrede, S., Bruun, T., Arnell, P., Rosén, A., Nekludov, M., Karlsson, Y., Bergey, F., Saccenti, E., Martins dos Santos, V. A. P., Perner, A., Norrby-Teglund, A. & Hyldegaard, O., Feb 2018, In : Acta Anaesthesiologica Scandinavica. 62, 2, p. 272-279

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Soft Tissue Infections
Observational Studies
Prospective Studies
Mortality
Necrotizing Fasciitis
5 Citations (Scopus)

Neochloris oleoabundans is worth its salt: Transcriptomic analysis under salt and nitrogen stress

de Jaeger, L., Carreres, B. M., Springer, J., Schaap, P. J., Eggink, G., Martins dos Santos, V. A. P., Wijffels, R. H. & Martens, D. E., 1 Apr 2018, In : PLoS ONE. 13, 4, e0194834.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Ettlia oleoabundans
Saline water
transcriptomics
saline water
Nitrogen
4 Citations (Scopus)

SAPP: functional genome annotation and analysis through a semantic framework using FAIR principles

Koehorst, J. J., van Dam, J. C. J., Saccenti, E., Martins Dos Santos, V. A. P., Suarez-Diez, M. & Schaap, P. J., 15 Apr 2018, In : Bioinformatics. 34, 8, p. 1401-1403

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Semantics
Annotation
Genome
Provenance
Genes

SyNDI: Synchronous network data integration framework

Lindfors, E., van Dam, J. C. J., Lam, C. M. C., Zondervan, N. A., Martins dos Santos, V. A. P. & Suarez-Diez, M., 6 Nov 2018, In : BMC Bioinformatics. 19, 1, 403.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Galaxies
Data integration
Data Integration
Computational Biology
Visualization
2017
4 Citations (Scopus)

Aspergillus niger secretes citrate to increase iron bioavailability

Odoni, D. I., van Gaal, M. P., Schonewille, T., Tamayo-Ramos, J. A., Martins dos Santos, V. A. P., Suarez-Diez, M. & Schaap, P. J., 2017, In : Frontiers in Microbiology. 8, AUG, 1424.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Aspergillus niger
Citric Acid
Biological Availability
Iron
Acids

Comparative proteomics of Rhizopus delemar ATCC 20344 unravels the role of amino acid catabolism in fumarate accumulation

Odoni, D. I., Tamayo-Ramos, J. A., Sloothaak, J., van Heck, R., Martins dos Santos, V. A. P., de Graaff, L. H., Suarez-Diez, M. & Schaap, P. J., 30 Mar 2017, In : PeerJ. 5, e3133.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Rhizopus
Fumarates
amino acid metabolism
Proteomics
proteomics
9 Citations (Scopus)

Draft genome sequence of the oleaginous green alga Tetradesmus obliquus UTEX 393

Carreres, B. M., de Jaeger, L., Springer, J., Barbosa, M. J., Breuer, G., van den End, E. J., Kleinegris, D. M. M., Schäffers, I., Wolbert, E. J. H., Zhang, H., Lamers, P. P., Martins dos Santos, V. A. P., Wijffels, R. H., Eggink, G., Schaap, P. J. & Martens, D. E., 2017, In : Genome Announcements. 5, 3, e01449-16.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Microalgae
Chlorophyta
Genome
Biofuels
Firearms
15 Citations (Scopus)
mucins
Mucins
lifestyle
Life Style
sugar
9 Citations (Scopus)

Genomic and functional analysis of Romboutsia ilealis CRIBT reveals adaptation to the small intestine

Gerritsen, J., Hornung, B., Renckens, B., van Hijum, S. A. F. T., Martins dos Santos, V. A. P., Rijkers, G. T., Schaap, P. J., de Vos, W. M. & Smidt, H., 2017, In : PeerJ. 2017, 9, 3698.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Functional analysis
Small Intestine
small intestine
Carbohydrates
carbohydrates
4 Citations (Scopus)

Identification of methylated GnTI-dependent N-glycans in Botryococcus brauni

Schulze, S., Urzica, E., Reijnders, M. J. M. F., van de Geest, H., Warris, S., Bakker, L. V., Fufezan, C., Martins dos Santos, V. A. P., Schaap, P. J., Peters, S. A. & Hippler, M., 2017, In : New Phytologist. 215, 4, p. 1361-1369

Research output: Contribution to journalArticleAcademicpeer-review

Botryococcus
Polysaccharides
polysaccharides
Microalgae
microalgae
2 Citations (Scopus)

Metabolic modeling of energy balances in Mycoplasma hyopneumoniae shows that pyruvate addition increases growth rate

Kamminga, T., Slagman, S. J., Bijlsma, J. J. E., Martins dos Santos, V. A. P., Suarez-Diez, M. & Schaap, P. J., 2017, In : Biotechnology and Bioengineering. 114, 10, p. 2339-2347

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Mycoplasma hyopneumoniae
Energy balance
Pyruvic Acid
Fermentation
Growth
2 Citations (Scopus)

Multi-level integration of environmentally perturbed internal phenotypes reveals key points of connectivity between them

Benis, N., Kar, S. K., Martins dos Santos, V. A. P., Smits, M. A., Schokker, D. & Suarez-Diez, M., 2017, In : Frontiers in Physiology. 8, 11 p., 388.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Phenotype
Genotype
Microbiota
Cytokines
Gene Expression
2 Citations (Scopus)

Persistence of functional protein domains in mycoplasma species and their role in host specificity and synthetic minimal life

Kamminga, T., Koehorst, J. J., Vermeij, P., Slagman, S. J., dos Santos, V. A. P. M., Bijlsma, J. J. E. & Schaap, P. J., 2017, In : Frontiers in Cellular and Infection Microbiology. 7, 31.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Mycoplasma
Host Specificity
Genome
Protein Domains
Host-Pathogen Interactions
3 Citations (Scopus)
Open Access
Enterocytes
Carbohydrates
Diet
Lipids
Cholesterol
1 Citation (Scopus)
Open Access
Genomics
Genes
Functional analysis
Proteins
Bacterial Genomes
2 Citations (Scopus)

Use of Microarray Datasets to generate Caco-2-dedicated Networks and to identify Reporter Genes of Specific Pathway Activity

Venkatasubramanian, P. B., Toydemir, G., de Wit, N., Saccenti, E., Martins dos Santos, V. A. P., van Baarlen, P., Wells, J. M., Suarez-Diez, M. & Mes, J. J., Jan 2017, In : Scientific Reports. 7, 1, 6778.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Reporter Genes
Caco-2 Cells
Computer Simulation
Genes
Food-Drug Interactions
2016

Characterizing the optimal flux space of genome-scale metabolic reconstructions through modified latin-hypercube sampling

Chaudhary, N., Tøndel, K., Bhatnagar, R., Martins dos Santos, V. A. P. & Puchalka, J., 2016, In : Molecular BioSystems. 12, 3, p. 994-1005

Research output: Contribution to journalArticleAcademicpeer-review

Genome
Metabolic Networks and Pathways
Principal Component Analysis
Pseudomonas aeruginosa
Saccharomyces cerevisiae
11 Citations (Scopus)

Comparison of 432 Pseudomonas strains through integration of genomic, functional, metabolic and expression data

Koehorst, J. J., van Dam, J. C. J., van Heck, R. G. A., Saccenti, E., Martins dos Santos, V., Suarez-Diez, M. & Schaap, P. J., 2016, In : Scientific Reports. 6, 13 p., 38699.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Pseudomonas
genomics
bioengineering
genome
bioremediation
9 Citations (Scopus)

Efficient Reconstruction of Predictive Consensus Metabolic Network Models

van Heck, R. G. A., Ganter, M., Martins dos Santos, V. A. P. & Stelling, J., 2016, In : PLoS Computational Biology. 12, 8, e1005085.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Host-Pathogen Interactions
Metabolic Network
Metabolic Networks and Pathways
Network Model
Genome
8 Citations (Scopus)

Functional Profiling of Unfamiliar Microbial Communities Using a Validated De Novo Assembly Metatranscriptome Pipeline

Davids, M., Hugenholtz, F., Martins dos Santos, V. A. P., Smidt, H., Kleerebezem, M. & Schaap, P. J., 2016, In : PLoS ONE. 11, 1, 18 p., e0146423.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
microbial communities
Pipelines
RNA
Genes
Genome
43 Citations (Scopus)

Harnessing the power of microbial autotrophy

Claassens, N. J., Machado de Sousa, D., Martins dos Santos, V., de Vos, W. M. & van der Oost, J., 2016, In : Nature Reviews Microbiology. 14, p. 692-706

Research output: Contribution to journalArticleAcademicpeer-review

Autotrophic Processes
Light
Semiconductors
Genetic Engineering
Biofuels
13 Citations (Scopus)

Identification and functional characterization of novel xylose transporters from the cell factories Aspergillus Niger and Trichoderma reesei

Sloothaak, J., Tamayo-Ramos, J. A., Odoni, D. I., Laothanachareon, T., Derntl, C., Mach-Aigner, A. R., Martins Dos Santos, V. A. P. & Schaap, P. J., 2016, In : Biotechnology for Biofuels. 9, 1, 148.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Trichoderma
Xylose
Aspergillus niger
Aspergillus
Industrial plants
13 Citations (Scopus)

Identification of a Novel L-rhamnose Uptake Transporter in the Filamentous Fungus Aspergillus niger

Sloothaak, J., Odoni, D. I., Martins dos Santos, V. A. P., Schaap, P. J. & Tamayo Ramos, J. A., 16 Dec 2016, In : Plos Genetics. 12, 12, e1006468.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Rhamnose
Aspergillus niger
rhamnose
transporters
Fungi
5 Citations (Scopus)

Integrated in silico analysis of pathway designs for synthetic photo-electro-autotrophy

Volpers, M., Claassens, N. J., Noor, E., van der Oost, J., de Vos, W. M., Kengen, S. W. M. & Martins dos Santos, V., 2016, In : PLoS ONE. 11, 6, e0157851.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Autotrophic Processes
Carbon Cycle
autotrophs
Computer Simulation
Calvin cycle
2 Citations (Scopus)
Open Access
Genomics
Genes
Proteins
Genome
Bacterial Genomes
7 Citations (Scopus)

Strategies for structuring interdisciplinary education in Systems Biology: an European perspective

Cvijovic, M., Höfer, T., Acimovic, J., Alberghina, L., Almaas, E., Besozzi, D., Blomberg, A., Bretschneider, T., Cascante, M., Collin, O., de Atauri, P., Depner, C., Dickinson, R., Dobrzynski, M., Fleck, C., Garcia-Ojalvo, J., Gonze, D., Hahn, J., Hess, H. M., Hollmann, S. & 13 othersKrantz, M., Kummer, U., Lundh, T., Martial, G., Martins dos Santos, V. A. P., Mauer-Oberthür, A., Regierer, B., Skene, B., Stalidzans, E., Stelling, J., Teusink, B., Workman, C. T. & Hohmann, S., 2016, In : npj Systems Biology and Applications. 2, 7 p., 16011.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Systems Biology
Education
Students
Curriculum
Industry
75 Citations (Scopus)

The revisited genome of Pseudomonas putida KT2440 enlightens its value as a robust metabolic chassis

Belda, E., van Heck, R. G. A., José Lopez-Sanchez, M., Cruveiller, S., Barbe, V., Fraser, C., Klenk, H. P., Petersen, J., Morgat, A., Nikel, P. I., Vallenet, D., Rouy, Z., Sekowska, A., Martins dos Santos, V. A. P., de Lorenzo, V., Danchin, A. & Médigue, C., 2016, In : Environmental Microbiology. 18, 10, p. 3403-3424

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Pseudomonas putida
genome
Genome
Bacteria
microorganisms
2015
14 Citations (Scopus)

Aspergillus niger membrane-associated proteome analysis for the identification of glucose transporters

Sloothaak, J., Odoni, D. I., de Graaff, L. H., Martins dos Santos, V. A. P., Schaap, P. J. & Tamayo Ramos, J. A., 2015, In : Biotechnology for Biofuels. 8, 15 p., 150.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Facilitative Glucose Transport Proteins
Aspergillus niger
Aspergillus
Proteome
Glucose
4 Citations (Scopus)

Assessing the Metabolic Diversity of Streptococcus from a Protein Domain Point of View

Saccenti, E., Nieuwenhuijse, D., Koehorst, J. J., Martins dos Santos, V. A. P. & Schaap, P. J., 2015, In : PLoS ONE. 10, 9, e0137908.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Streptococcus
Metabolic Networks and Pathways
biochemical pathways
Bacteria
Streptococcus suis
34 Citations (Scopus)

Comprehensive insights into transcriptional adaptation of intracellular mycobacteria by microbe-enriched dual RNA sequencing

Rienksma, R. A., Suarez Diez, M., Mollenkopf, H. J., Dolganov, G. M., Dorhoi, A., Schoolnik, G. K., Martins Dos Santos, V. A. P., Kaufmann, S., Schaap, P. J. & Gengenbacher, M., 2015, In : BMC Genomics. 16, 31 p., 34.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
RNA Sequence Analysis
Mycobacterium
Infection
Transcriptome
Mycobacterium tuberculosis

Erratum to: Green genes: Bioinformatics and systems-biology innovations drive algal biotechnology [Trends in Biotechnology 32 (2014) 617-626].

Reijnders, M. J. M. F., van Heck, R. G. A., Lam, C. M. C., Scaife, M. A., Martins dos Santos, V. A. P., Smith, A. G. & Schaap, P. J., 2015, In : Trends in Biotechnology. 33, 5, p. 315

Research output: Contribution to journalArticleAcademic

15 Citations (Scopus)

Genotypic and phenotypic analyses of a Pseudomonas aeruginosa chronic bronchiectasis isolate reveal differences from cystic fibrosis and laboratory strains

Varga, J. J., Barbier, M., Mulet, X., Bielecki, P., Bartell, J. A., Owings, J. P., Martinez-Ramos, I., Hittle, L. E., Davis, M. R., Damron, F. H., Liechti, G. W., Puchałka, J., Martins dos Santos, V., Ernst, R. K., Papin, J. A., Albertí, S., Oliver, A. & Goldberg, J. B., 2015, In : BMC Genomics. 16, 1, 27 p., 883.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Bronchiectasis
Cystic Fibrosis
Pseudomonas aeruginosa
Respiratory Tract Infections
Genome
2 Citations (Scopus)

Network analysis of temporal functionalities of the gut induced by perturbations in new-born piglets

Benis, N., Schokker, D., Suarez Diez, M., Martins dos Santos, V. A. P., Smidt, H. & Smits, M. A., 2015, In : BMC Genomics. 16, 556.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Biological Phenomena
Gene Expression
Anti-Bacterial Agents
Systems Biology
Health
5 Citations (Scopus)

RDF2Graph a tool to recover, understand and validate the ontology of an RDF resource

van Dam, J. C. J., Koehorst, J. J., Schaap, P. J., Martins dos Santos, V. A. P. & Suarez Diez, M., 2015, In : Journal of Biomedical Semantics. 6, 12 p., 39.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Semantic Web
Semantics
Ontology
Technology
Structural integrity

Synthetische biologie komende jaren in het vizier

Sikkema, A. & Martins dos Santos, V. A. P., 2015, In : Resource: weekblad voor Wageningen UR. 9, 20, p. 12-13

Research output: Contribution to journalArticlePopular

2014
3 Citations (Scopus)

Delineating the effect of host environmental signals on a fully virulent strain of Bacillus anthracis using an integrated transcriptomics and proteomics approach

Panda, G., Basak, T., Tanwer, P., Sengupta, S., Martins dos Santos, V. A. P. & Bhatnagar, R., 2014, In : Journal of Proteomics. 105, p. 242-265

Research output: Contribution to journalArticleAcademicpeer-review

Bacillus anthracis
Bacilli
Metabolism
Proteomics
Genes
34 Citations (Scopus)

Effects of ß-Lactam Antibiotics and Fluoroquinolones on Human Gut Microbiota in Relation to Clostridium difficile Associated Diarrhea

Knecht, H., Neulinger, S. C., Heinsen, F. A., Knecht, C., Schilhabel, A., Schmitz, R. A., Zimmermann, A., Martins dos Santos, V. A. P., Ferrer, R., Rosenstiel, P. C., Schreiber, S., Friedrichs, A. K. & Ott, S. J., 2014, In : PLoS ONE. 9, 2, e89417.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
lactams
Clostridium difficile
Lactams
Clostridium
fluoroquinolones
16 Citations (Scopus)

From the Environment to the Host: Re-Wiring of the Transcriptome of Pseudomonas aeruginosa from 22°C to 37°C

Barbier, M., Damron, F. H., Bielecki, P., Suarez Diez, M., Puchalka, J., Albertí, S., Martins Dos Santos, V. A. P. & Goldberg, J. B., 2014, In : PLoS ONE. 9, 2, e89941.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Electric wiring
Transcriptome
Pseudomonas aeruginosa
transcriptome
Genes