If you made any changes in Pure these will be visible here soon.

Research Output 2014 2019

2019
Open Access
Saponins
Immersion
Zebrafish
Larva
Fertilization
1 Citation (Scopus)

Corrigendum: Sialyllactose and Galactooligosaccharides Promote Epithelial Barrier Functioning and Distinctly Modulate Microbiota Composition and Short Chain Fatty Acid Production In Vitro

Perdijk, O., van Baarlen, P., Fernandez-Gutierrez, M. M., van den Brink, E., Schuren, F. H. J., Brugman, S., Savelkoul, H. F. J., Kleerebezem, M. & van Neerven, R. J. J., 10 Apr 2019, In : Frontiers in Immunology. 10, 1 p.

Research output: Contribution to journalComment/Letter to the editorAcademic

Open Access
Volatile Fatty Acids
Microbiota
In Vitro Techniques
corrigendum
N-acetylneuraminoyllactose
Open Access
Volatile Fatty Acids
Microbiota
Oligosaccharides
Human Milk
Prebiotics
2018
3 Citations (Scopus)

BAFF augments IgA2 and IL-10 production by TLR7/8 stimulated total peripheral blood B cells

den Hartog, C. G., van Osch, T. L. J., Vos, M., Meijer, B., Savelkoul, H. F. J., van Neerven, R. J. J. & Brugman, S., 9 Feb 2018, In : European journal of immunology. 48, 2, p. 283-292

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Interleukin-10
Immunoglobulin A
Blood Cells
B-Lymphocytes
Virus Diseases
2 Citations (Scopus)

Bovine lactoferrin enhances TLR7-mediated responses in plasmacytoid dendritic cells in elderly women: Results from a nutritional intervention study with bovine lactoferrin, GOS and Vitamin D

van Splunter, M., Perdijk, O., Fick-Brinkhof, H., Feitsma, A. L., Floris-Vollenbroek, E. G., Meijer, B., Brugman, S., Savelkoul, H. F. J., van Hoffen, E. & van Neerven, R. J. J., 20 Nov 2018, In : Frontiers in Immunology. 9, 2677.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Lactoferrin
Vitamin D
Dendritic Cells
Toll-Like Receptors
Placebos

Bovine lactoferrin inhibits dendritic cell differentiation and induces small intestine homing on T cells

Perdijk, O. I. J., van Neerven, R. J. J., van den Brink, E., Meijer, B., Savelkoul, H. F. J. & Brugman, S., 2018, p. 23-23. 1 p.

Research output: Contribution to conferenceAbstractAcademic

3 Citations (Scopus)

Bovine lactoferrin modulates dendritic cell differentiation and function

Perdijk, O., van Neerven, R. J. J., van den Brink, E., Savelkoul, H. F. J. & Brugman, S., 29 Jun 2018, In : Nutrients. 10, 7, 848.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Lactoferrin
lactoferrin
dendritic cells
cell differentiation
Dendritic Cells

Comparative review on microbiota manipulation: lessons from fish, plants, livestock and human research

Brugman, S., Ikeda-Ohtsubo, W., Braber, S., Folkerts, G., Pieterse, C. M. J. & Bakker, P. A. H. M., 5 Sep 2018, In : Frontiers in Nutrition. 5, 15 p., 80.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Microbiota
Dysbiosis
Livestock
Fishes
livestock
8 Citations (Scopus)

Cow's milk and immune function in the respiratory tract: Potential mechanisms

Perdijk, O., van Splunter, M., Savelkoul, H. F. J., Brugman, S. & van Neerven, J., 12 Feb 2018, In : Frontiers in Immunology. 9, FEB, 143.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Respiratory System
Milk
Respiratory Tract Infections
Asthma
Allergens
Open Access
Saponins
Immersion
Zebrafish
Larva
Anti-Bacterial Agents

How can we define "optimal microbiota?": a comparative review of structure and functions of microbiota of animals, fish and plants in agriculture

Ikeda-Ohtsubo, W., Brugman, S., Warden, C. H., Rebel, A., Folkerts, G. & Pieterse, C. M. J., 28 Nov 2018, In : Frontiers in Nutrition. 5, 113, 18 p., 90.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Microbiota
Agriculture
Fishes
agriculture
fish

Immune modulation by cow’s milk components: Implications for respiratory health

Perdijk, O. IJ., 2018, Wageningen: Wageningen University. 268 p.

Research output: Thesisinternal PhD, WUAcademic

Open Access

Immunomodulation by raw bovine milk and its ingredients: effects in nutritional intervention, oral vaccination and trained immunity

van Splunter, M. E., 2018, Wageningen: Wageningen University. 270 p.

Research output: Thesisinternal PhD, WUAcademic

Open Access
7 Citations (Scopus)

Induction of human tolerogenic dendritic cells by 3′-sialyllactose via TLR4 is explained by LPS contamination

Perdijk, O., Joost Van Neerven, R. J., Meijer, B., Savelkoul, H. F. J. & Brugman, S., 1 Mar 2018, In : Glycobiology. 28, 3, p. 126-130

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Dendritic Cells
Contamination
3'-sialyllactose
Toll-Like Receptor 4
Toll-Like Receptors
1 Citation (Scopus)

Induction of trained innate immunity in human monocytes by bovine milk and milk-derived immunoglobulin G

van Splunter, M., van Osch, T. L. J., Brugman, S., Savelkoul, H. F. J., Joosten, L. A. B., Netea, M. G. & van Neerven, R. J. J., 27 Sep 2018, In : Nutrients. 10, 10, 1378.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
immunoglobulin G
Innate Immunity
monocytes
Monocytes
Milk

Onderzoek naar het ontstaan van darmontstekingen: het zebravismodel

Brugman, S., Forlenza, M. & Wiegertjes, G., 2018, In : Biotechniek. 57, 1, p. 9-14

Research output: Contribution to journalArticleProfessional

Open Access
3 Citations (Scopus)

Oral cholera vaccination promotes homing of IgA+ memory B cells to the large intestine and the respiratory tract

van Splunter, M., van Hoffen, E., Floris-Vollenbroek, E. G., Timmerman, H., van de Bos, E. L., Meijer, B., Ulfman, L. H., Witteman, B., Wells, J. M., Brugman, S., Savelkoul, H. F. J. & van Neerven, R. J. J., 2018, In : Mucosal Immunology. 11, 4, p. 1254-1264

Research output: Contribution to journalArticleAcademicpeer-review

Cholera
Large Intestine
Respiratory System
Immunoglobulin A
Vaccination
2 Citations (Scopus)

Prenatal developmental toxicity testing of petroleum substances using the zebrafish embryotoxicity test

Kamelia, L., Brugman, S., de Haan, L. H. J., Ketelslegers, H. B., Rietjens, I. M. C. M. & Boogaard, P., 7 Dec 2018, In : Altex. 36, 2, p. 245-260

Research output: Contribution to journalArticleAcademicpeer-review

Petroleum
Zebrafish
Embryonic Stem Cells
Polycyclic Aromatic Hydrocarbons
Gases

Saponin induces an inflammatory phenotype and microbiome shift in zebrafish larvae

Lopez Nadal, A., Peggs, D., Wiegertjes, G. & Brugman, S., 2018.

Research output: Contribution to conferenceAbstractAcademic

4 Citations (Scopus)
Open Access
galactooligosaccharides
dendritic cells
Oligosaccharides
oligosaccharides
cell differentiation

T lymphocytes actively suppress intestinal pathobionts in zebrafish

Lopez Nadal, A., Boekhorst, J., Timmerman, H. M., Kleerebezem, M. & Brugman, S., 2018, p. 41-41. 1 p.

Research output: Contribution to conferenceAbstractAcademic

2017
1 Citation (Scopus)

Oxazolone-induced intestinal inflammation in adult zebrafish

Brugman, S. & Nieuwenhuis, E. E. S., 2017, Inflammation. Clausen, B. E. & Laman, J. D. (eds.). Humana Press Inc., p. 311-318 (Methods in Molecular Biology; vol. 1559).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Oxazolone
Zebrafish
Inflammation
Haptens
Immunity
2016
57 Citations (Scopus)

The zebrafish as a model to study intestinal inflammation

Brugman, S., 2016, In : Developmental and Comparative Immunology. 64, p. 82-92

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Zebrafish
Inflammation
Mammals
Fishes
Developmental Biology

Tissue-specific homing potential and kinetics of B and T cell responses to oral cholera vaccination

van Splunter, M. E., Timmerman, H. M., Ulfman, L. H., Witteman, B. J. M., Wells, J. M., Brugman, S., Savelkoul, H. F. J., van Hoffen, E. & van Neerven, R. J. J., 2016, p. C1032-6 . 2 p.

Research output: Contribution to conferenceAbstractAcademic

2015
20 Citations (Scopus)

Mucosal immune development in early life: setting the stage

Brugman, S., Perdijk, O. I. J., van Neerven, R. J. J. & Savelkoul, H. F. J., 2015, In : Archivum Immunologiae et Therapiae Experimentalis. 63, 4, p. 251-268

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Immune System
Infant, Newborn, Diseases
Immunity
Epithelial Cells
Food

T lymphocytes control microbial composition by actively suppressing overgrowth of pathogenic bacteria in the zebrafish gut

Brugman, S., Suijker, K., Doro, E., Forlenza, M. & Wiegertjes, G., 27 Aug 2015.

Research output: Contribution to conferenceAbstractAcademic

Using zebrafish to study mucosal immunity and microbial composition in the presence and absence of adaptive immunity

Brugman, S., Suijker, K., Doro, E., Forlenza, M. & Wiegertjes, G., 2015, p. 56, W111. 1 p.

Research output: Contribution to conferenceAbstractAcademic

2014
9 Citations (Scopus)

Deficiency of macrophage stimulating protein results in spontaneous inflammation and increased susceptibility towards epithelial damage in zebrafish

Witte, M., Huitema, L. F., Nieuwenhuis, E. E. S. & Brugman, S., 2014, In : Zebrafish. 11, 6, p. 542-550

Research output: Contribution to journalArticleAcademicpeer-review

Zebrafish
Danio rerio
macrophages
inflammation
Inflammation
13 Citations (Scopus)

T-lymphocyte-dependent and independent regulation of Cxcl8 expression in zebrafish intestine

Brugman, S., Witte, M., Scholman, R. C., Klein, M., Boes, M. & Nieuwenhuis, E. E. S., 2014.

Research output: Contribution to conferenceAbstractAcademic

11 Citations (Scopus)

T lymphocytes control microbial composition by regulating the abundance of Vibrio in the zebrafish gut

Brugman, S., Schneeberger, K., Witte, M. & Klein, M. R., 2014, In : Gut Microbes. 5, 6, p. 737-747

Research output: Contribution to journalArticleAcademicpeer-review

Vibrio
Zebrafish
Adaptive Immunity
T-Lymphocytes
Microbiota

T-lymphocytes control microbial composition by regulating the abundance of Vibrio in the zebrafish gut

Brugman, S., 2014.

Research output: Contribution to conferenceAbstractAcademic