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Research Output 1995 2019

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Article
2015
12 Citations (Scopus)

Nutrient Intake by Ultramarathon Runners: Can They Meet Recommendations?

Wardenaar, F. C., de Vries, J. H. M., Witkamp, R. F. & Mensink, M. R., 2015, In : International Journal of Sport Nutrition & Exercise Metabolism. 25, 4, p. 375-386

Research output: Contribution to journalArticleAcademicpeer-review

Food
Recommended Dietary Allowances
Nonparametric Statistics
Sports
Carbohydrates
29 Citations (Scopus)

Tolerability and safety of souvenaid in patients with mild Alzheimer's disease: Results of multi-center, 24-week, open-label extension study

Olde Rikkert, M. G. M., Verhey, F. R., Blesa, R., Von Arnim, C. A. F., Bongers, A., Harrison, J., Sijben, J., Scarpini, E., Vandewoude, M. F. J., Vellas, B., Witkamp, R., Kamphuis, P. J. G. H. & Scheltens, P., 2015, In : Journal of Alzheimers Disease. 44, 2, p. 471-480 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Alzheimer Disease
Randomized Controlled Trials
Safety
Food
Neuropsychological Tests
10 Citations (Scopus)
Athletes
Nitrogen
Dietary Proteins
Proteins
Urine
24 Citations (Scopus)
Vitamin D
Epidemiologic Studies
Colorectal Neoplasms
Inflammation
Cytokines
2016
7 Citations (Scopus)
Interleukin-17
Omega-3 Fatty Acids
Serotonin
Anti-Inflammatory Agents
Macrophages
27 Citations (Scopus)

Fatty acids, endocannabinoids and inflammation

Witkamp, R., 2016, In : European Journal of Pharmacology. 785, p. 96-107

Research output: Contribution to journalArticleAcademicpeer-review

Endocannabinoids
Fatty Acids
Inflammation
Physiological Phenomena
Ligands

Geneesmiddelgebruik, ondervoeding en deficiënties bij ouderen

van Orten-Luiten, A. C. B., Janse, A. & Witkamp, R. F., 2016, In : MFM- praktijkgerichte nascholing over farmacotherapie. editie 2

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)

Hypothalamic inflammation and food intake regulation during chronic illness

Dwarkasing, J. T., Marks, D. L., Witkamp, R. F. & van Norren, K., 2016, In : Peptides. 77, p. 60-66

Research output: Contribution to journalArticleAcademicpeer-review

Appetite Regulation
Chronic Disease
Inflammation
Eating
Pro-Opiomelanocortin
10 Citations (Scopus)

Increased hypothalamic serotonin turnover in inflammation-induced anorexia

Dwarkasing, J. T., Witkamp, R. F., Boekschoten, M. V., ter Laak, M. C., Heins, M. S. & van Norren, K., 2016, In : BMC Neuroscience. 17, 1, 26.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Anorexia
Serotonin
Inflammation
Interleukin-6
Hypothalamus
3 Citations (Scopus)

Moderate alcohol consumption after a mental stressor attenuates the endocrine stress response

Schrieks, I. C., Joosten, M. M., Klöpping-Ketelaars, W. A. A., Witkamp, R. F. & Hendriks, H. F. J., 2016, In : Alcohol. 57, p. 29-34

Research output: Contribution to journalArticleAcademicpeer-review

alcohol consumption
Alcohol Drinking
alcohol
Alcohols
Beer
8 Citations (Scopus)

Nutrient-induced glucagon like peptide-1 release is modulated by serotonin

Ripken, D., van der Wielen, N., Wortelboer, H. M., Meijerink, J., Witkamp, R. F. & Hendriks, H. F. J., 2016, In : Journal of Nutritional Biochemistry. 32, p. 142-150

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Glucagon-Like Peptide 1
Nutrients
Serotonin
Food
Safflower Oil
10 Citations (Scopus)

The effect of endurance exercise on intestinal integrity in well-trained healthy men

Janssen Duijghuijsen, L., Mensink, M., Lenaerts, K., Fiedorowicz, E., van Dartel, D. A. M., Mes, J. J., Luiking, Y. C., Keijer, J., Wichers, H. J., Witkamp, R. F. & van Norren, K., 1 Oct 2016, In : Physiological Reports. 4, 20, e12994.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Exercise
Lactulose
Rhamnose
Permeability
Glucagon-Like Peptide 2
10 Citations (Scopus)

The noncaloric sweetener rebaudioside a stimulates glucagon-like peptide 1 release and increases enteroendocrine cell numbers in 2-dimensional mouse organoids derived from different locations of the intestine

van der Wielen, N., ten Klooster, J. P., Muckenschnabl, S., Pieters, R., Hendriks, H. F. J., Witkamp, R. F. & Meijerink, J., 2016, In : The Journal of Nutrition. 146, 12, p. 2429-2435

Research output: Contribution to journalArticleAcademicpeer-review

Organoids
Enteroendocrine Cells
Sweetening Agents
Glucagon-Like Peptide 1
Intestines
11 Citations (Scopus)
Open Access
Polypharmacy
Vitamin D Deficiency
Drug-Related Side Effects and Adverse Reactions
Geriatrics
Outpatients
2017
4 Citations (Scopus)

Adaptation of exercise-induced stress in well-trained healthy young men

Janssen Duijghuijsen, L. M., Keijer, J., Mensink, M. R., Lenaerts, K., Ridder, L. O., Nierkens, S., Kartaram, S., Verschuren, M. C. M., Pieters, R., Bas, R., Witkamp, R. F., Wichers, H. J. & van Norren, K., 2017, In : Experimental Physiology. 102, 1, p. 86-99

Research output: Contribution to journalArticleAcademicpeer-review

Exercise
Lactulose
Rhamnose
Energy Metabolism
Urine
5 Citations (Scopus)

Beta-blocker use and fall risk in older individuals: Original results from two studies with meta-analysis

Ham, A. C., van Dijk, S. C., Swart, K. M. A., Enneman, A. W., van der Zwaluw, N. L., Brouwer-Brolsma, E. M., van Schoor, N. M., Zillikens, M. C., Lips, P., de Groot, L. C. P. G. M., Hofman, A., Witkamp, R. F., Uitterlinden, A. G., Stricker, B. H. & van der Velde, N., 2017, In : British Journal of Clinical Pharmacology. 83, 10, p. 2292-2302

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Meta-Analysis
Cytochrome P-450 CYP2D6
Solubility
Odds Ratio
Confidence Intervals
6 Citations (Scopus)

CYP2C9 genotypes modify benzodiazepine-related fall risk: Original results from three studies with meta-analysis

Ham, A. C., Ziere, G., Broer, L., van Wijngaarden, J. P., van der Zwaluw, N. L., Brouwer, E. M., Dhonukshe-Rutten, R. A. M., de Groot, C. P. G. M. & Witkamp, R. F., 2017, In : Journal of the American Medical Directors Association. 18, 1, p. 88.e1-88.e15

Research output: Contribution to journalArticleAcademicpeer-review

Benzodiazepines
Meta-Analysis
Genotype
Alleles
Confidence Intervals
2 Citations (Scopus)
Athletes
Magnesium
Exercise
Athletic Performance
Research
7 Citations (Scopus)

Detection of peanut allergen in human blood after consumption of peanuts is skewed by endogenous immunoglobulins

Janssen Duijghuijsen, L. M., Wichers, H. J., van Norren, K., Keijer, J., Baumert, J. L., De Jong, G. A. H., Witkamp, R. F. & Koppelman, S. J., 2017, In : Journal of Immunological Methods. 440, p. 52-57

Research output: Contribution to journalArticleAcademicpeer-review

Allergens
Immunoglobulins
Immunoglobulin G
Serum
Eating
8 Citations (Scopus)
Interleukin-17
Blood Cells
Serotonin
Fatty Acids
Interleukin-23
6 Citations (Scopus)

Endurance exercise increases intestinal uptake of the peanut allergen Ara h 6 after peanut consumption in humans

Janssen Duijghuijsen, L. M., Van Norren, K., Grefte, S., Koppelman, S. J., Lenaerts, K., Keijer, J., Witkamp, R. F. & Wichers, H. J., 2017, In : Nutrients. 9, 1, 84.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Lactulose
allergens
peanuts
lactulose
exercise
1 Citation (Scopus)

Intraileal casein infusion increases plasma concentrations of amino acids in humans: A randomized cross over trial

Ripken, D., van Avesaat, M., Troost, F. J., Masclee, A. A., Witkamp, R. F. & Hendriks, H. F., 2017, In : Clinical Nutrition. 36, 1, p. 143-149

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Caseins
Cross-Over Studies
Amino Acids
Oxylipins
C-Reactive Protein
3 Citations (Scopus)

Macronutrient Intakes in 553 Dutch Elite and Sub-Elite Endurance, Team, and Strength Athletes: Does Intake Differ between Sport Disciplines?

Wardenaar, F., Brinkmans, N., Ceelen, I., Van Rooij, B., Mensink, M., Witkamp, R. & De Vries, J., 2017, In : Nutrients. 9, 2, 119.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
athletes
sports
Athletes
Sports
Energy Intake
12 Citations (Scopus)

Micronutrient Intakes in 553 Dutch Elite and Sub-Elite Athletes: Prevalence of Low and High Intakes in Users and Non-Users of Nutritional Supplements

Wardenaar, F., Brinkmans, N., Ceelen, I., Van Rooij, B., Mensink, M., Witkamp, R. & De Vries, J., 2017, In : Nutrients. 9, 2, 142.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Micronutrients
athletes
dietary minerals
Athletes
dietary supplements
12 Citations (Scopus)
Endocannabinoids
Macrophage Activation
Docosahexaenoic Acids
Macrophages
Omega-3 Fatty Acids
12 Citations (Scopus)

Nutritional Supplement Use by Dutch Elite and Sub-Elite Athletes: Does Receiving Dietary Counselling Make a Difference?

Wardenaar, F. C., Ceelen, I. J. M., van Dijk, J. W., Hangelbroek, R. W. J., van Roy, L., van der Pouw, B., de Vries, J. H. M., Mensink, M. R. & Witkamp, R. F., 2017, In : International Journal of Sport Nutrition & Exercise Metabolism. 27, 1, p. 32-42

Research output: Contribution to journalArticleAcademicpeer-review

Athletes
Counseling
Sports
Energy Drinks
beta-Alanine
12 Citations (Scopus)

Optimal nutrition and the ever-changing dietary landscape: a conference report

Shao, A., Drewnowski, A., Willcox, D. C., Krämer, L., Lausted, C., Eggersdorfer, M., Mathers, J., Bell, J. D., Randolph, R. K., Witkamp, R. & Griffiths, J. C., 2017, In : European Journal of Nutrition. 56, suppl.1, 21 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Food
Nutritional Sciences
Sedentary Lifestyle
Deficiency Diseases
Nutrition Policy
6 Citations (Scopus)

Public health relevance of drug–nutrition interactions

Péter, S., Navis, G., de Borst, M. H., von Schacky, C., van Orten-Luiten, A. C. B., Zhernakova, A., Witkamp, R. F., Janse, A., Weber, P., Bakker, S. L. J. & Eggersdorfer, M., 2017, In : European Journal of Nutrition. 56, suppl. 2, p. 23-36

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Public Health
Pharmaceutical Preparations
Polypharmacy
Food
Drug Evaluation
Open Access
oxaliplatin
Observational Studies
Colorectal Neoplasms
Skeletal Muscle
Retrospective Studies
7 Citations (Scopus)
Serotonin
Cachexia
Inflammation
Anorexia
Neoplasms
2018
1 Citation (Scopus)

Associations of hyperosmolar medications administered via nasogastric or nasoduodenal tubes and feeding adequacy, food intolerance and gastrointestinal complications amongst critically ill patients: A retrospective study

Wesselink, E., Koekkoek, K. W. A. C., Looijen, M., van Blokland, D. A., Witkamp, R. F. & van Zanten, A. R. H., Jun 2018, In : Clinical Nutrition ESPEN. 25, p. 78-86

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Enteral Nutrition
Critical Illness
Retrospective Studies
Food
Diarrhea
2 Citations (Scopus)
Open Access
Microfluidics
HEK293 Cells
G-Protein-Coupled Receptors
calcium
Calcium
2 Citations (Scopus)

Changes in iron metabolism during prolonged repeated walking exercise in middle-aged men and women

Terink, R., ten Haaf, D., Bongers, C. W. G., Balvers, M. G. J., Witkamp, R. F., Mensink, M., Eijsvogels, T. M. H., Klein Gunnewiek, J. M. T. & Hopman, M. T. E., Nov 2018, In : European Journal of Applied Physiology. 118, 11, p. 2349–2357

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Walking
Iron
Exercise
Haptoglobins
Ferritins
1 Citation (Scopus)

Drug use is associated with lower plasma magnesium levels in geriatric outpatients; possible clinical relevance

van Orten-Luiten, A. C. B., Janse, A., Verspoor, E., Brouwer-Brolsma, E. M. & Witkamp, R. F., 6 Dec 2018, In : Clinical Nutrition.

Research output: Contribution to journalArticleAcademicpeer-review

Geriatrics
Magnesium
Outpatients
Pharmaceutical Preparations
Polypharmacy
11 Citations (Scopus)

Fish oil LC-PUFAs do not affect blood coagulation parameters and bleeding manifestations: Analysis of 8 clinical studies with selected patient groups on omega-3-enriched medical nutrition

Jeansen, S., Witkamp, R. F., Garthoff, J. A., van Helvoort, A. & Calder, P. C., Jun 2018, In : Clinical Nutrition. 37, 3, p. 948-957

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Fish Oils
Omega-3 Fatty Acids
Blood Coagulation
Hemorrhage
Vulnerable Populations
2 Citations (Scopus)

Increasing quality of life in pulmonary arterial hypertension: is there a role for nutrition?

Vinke, P., Jansen, S. M., Witkamp, R. F. & van Norren, K., Aug 2018, In : Heart Failure Reviews. 23, 5, p. 711–722

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Pulmonary Hypertension
Quality of Life
Exercise
Fatigue
Micronutrients
3 Citations (Scopus)

In vitro anti-inflammatory and radical scavenging properties of chinotto (Citrus myrtifolia Raf.) essential oils

Plastina, P., Apriantini, A., Meijerink, J., Witkamp, R., Gabriele, B. & Fazio, A., 18 Jun 2018, In : Nutrients. 10, 6, 783.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Citrus
Volatile Oils
essential oils
Anti-Inflammatory Agents
Fruit
5 Citations (Scopus)

Let thy food be thy medicine….when possible

Witkamp, R. F. & van Norren, K., 5 Oct 2018, In : European Journal of Pharmacology. 836, p. 102-114

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Medicine
Food
Life Style
Health Transition
Food-Drug Interactions

Release of major peanut allergens from their matrix under various pH and simulated saliva conditions—Ara h2 and ara h6 are readily bio-accessible

Koppelman, S. J., Smits, M., Tomassen, M., De Jong, G. A. H., Baumert, J., Taylor, S. L., Witkamp, R., Veldman, R. J., Pieters, R. & Wichers, H., 11 Sep 2018, In : Nutrients. 10, 9, 1281.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
allergens
saliva
Saliva
Allergens
peanuts
6 Citations (Scopus)

The role of fatty acids and their endocannabinoid-like derivatives in the molecular regulation of appetite

Witkamp, R. F., Dec 2018, In : Molecular Aspects of Medicine. 64, p. 45-67

Research output: Contribution to journalArticleAcademicpeer-review

Appetite Regulation
Endocannabinoids
Fatty Acids
Derivatives
Feeding Behavior
2019

A Diet Rich in Fish Oil and Leucine Ameliorates Hypercalcemia in Tumour-Induced Cachectic Mice

Plas, R. L. C., Poland, M., Faber, J., Argilès, J., van Dijk, M., Laviano, A., Meijerink, J., Witkamp, R. F., van Helvoort, A. & van Norren, K., 9 Oct 2019, In : International Journal of Molecular Sciences. 20, 20, 4978.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
diets
leucine
Fish Oils
fishes
Hypercalcemia

Anti-inflammatory nutrition with high protein attenuates cardiac and skeletal muscle alterations in a pulmonary arterial hypertension model

Vinke, P., Bowen, T. S., Boekschoten, M. V., Witkamp, R. F., Adams, V. & van Norren, K., 15 Jul 2019, In : Scientific Reports. 9, 1, 10160.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Monocrotaline
Pulmonary Hypertension
Myocardium
Skeletal Muscle
Anti-Inflammatory Agents
2 Citations (Scopus)

Capsaicin analogues derived from n-3 polyunsaturated fatty acids (PUFAs) reduce inflammatory activity of macrophages and stimulate insulin secretion by β-cells in vitro

Cione, E., Plastina, P., Pingitore, A., Perri, M., Caroleo, M. C., Fazio, A., Witkamp, R. & Meijerink, J., 1 Apr 2019, In : Nutrients. 11, 4, 915.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
capsaicin
long chain polyunsaturated fatty acids
insulin secretion
Capsaicin
Omega-3 Fatty Acids
3 Citations (Scopus)

Feeding mitochondria: Potential role of nutritional components to improve critical illness convalescence

Wesselink, E., Koekkoek, W. A. C., Grefte, S., Witkamp, R. F. & van Zanten, A. R. H., Jun 2019, In : Clinical Nutrition. 38, 3, p. 982-995

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
coenzyme Q10
Micronutrients
Critical Illness
Mitochondria
Selenium
5 Citations (Scopus)

Identification of hydroxytyrosyl oleate, a derivative of hydroxytyrosol with anti-inflammatory properties, in olive oil by-products

Plastina, P., Benincasa, C., Perri, E., Fazio, A., Augimeri, G., Poland, M., Witkamp, R. & Meijerink, J., 1 May 2019, In : Food Chemistry. 279, p. 105-113

Research output: Contribution to journalArticleAcademicpeer-review

Oleic Acid
anti-inflammatory activity
olive oil
byproducts
oleic acid

Ionized and Total Magnesium Levels Change during Repeated Exercise in Older Adults

Terink, R., Balvers, M. G., Bongers, C. C. W. G., Eijsvogels, T. M. H., Witkamp, R. F., Mensink, M., Hopman, M. T. & Klein Gunnewiek, J. M. T., Jun 2019, In : Journal of Nutrition, Health and Aging. 23, 6, p. 595-601 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Magnesium
Walking
Exercise
Health
Population

N-Eicosapentaenoyl Dopamine, A Conjugate of Dopamine and Eicosapentaenoic Acid (EPA), Exerts Anti-inflammatory Properties in Mouse and Human Macrophages

Augimeri, G., Plastina, P., Gionfriddo, G., Rovito, D., Giordano, C., Fazio, A., Barone, I., Catalano, S., Andò, S., Bonofiglio, D., Meijerink, J. & Witkamp, R., 18 Sep 2019, In : Nutrients. 11, 9, 2247.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Eicosapentaenoic Acid
eicosapentaenoic acid
dopamine
anti-inflammatory activity
Dopamine

Novel COX-2 products of n-3 polyunsaturated fatty acid-ethanolamine-conjugates identified in RAW264.7 macrophages

de Bus, I., Zuilhof, H., Witkamp, R., Balvers, M. & Albada, B., Nov 2019, In : Journal of Lipid Research. 60, 11, p. 1829-1840

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Ethanolamine
Macrophages
Omega-3 Fatty Acids
Cyclooxygenase 2
Metabolites

Plasma citrulline concentration, a marker for intestinal functionality, reflects exercise intensity in healthy young men

Kartaram, S., Mensink, M., Teunis, M., Schoen, E., Witte, G., Janssen Duijghuijsen, L., Verschuren, M., Mohrmann, K., M'Rabet, L., Knipping, K., Wittink, H., van Helvoort, A., Garssen, J., Witkamp, R., Pieters, R. & van Norren, K., Oct 2019, In : Clinical Nutrition. 38, 5, p. 2251-2258 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Citrulline
Glutamine
Exercise
Workload
Amino Acids
Open Access
Calcium
DNA
Calcium-Sensing Receptors
Proteins
Oligonucleotide Array Sequence Analysis