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Research Output 1995 2019

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Article
2015
11 Citations (Scopus)

Nutrient Intake by Ultramarathon Runners: Can They Meet Recommendations?

Wardenaar, F. C., de Vries, J. H. M., Witkamp, R. F. & Mensink, M. R., 2015, In : International Journal of Sport Nutrition & Exercise Metabolism. 25, 4, p. 375-386

Research output: Contribution to journalArticleAcademicpeer-review

Food
Recommended Dietary Allowances
Nonparametric Statistics
Sports
Carbohydrates
27 Citations (Scopus)

Tolerability and safety of souvenaid in patients with mild Alzheimer's disease: Results of multi-center, 24-week, open-label extension study

Olde Rikkert, M. G. M., Verhey, F. R., Blesa, R., Von Arnim, C. A. F., Bongers, A., Harrison, J., Sijben, J., Scarpini, E., Vandewoude, M. F. J., Vellas, B., Witkamp, R., Kamphuis, P. J. G. H. & Scheltens, P., 2015, In : Journal of Alzheimers Disease. 44, 2, p. 471-480 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Alzheimer Disease
Randomized Controlled Trials
Safety
Food
Neuropsychological Tests
9 Citations (Scopus)
Athletes
Nitrogen
Dietary Proteins
Proteins
Urine
23 Citations (Scopus)
Vitamin D
Epidemiologic Studies
Colorectal Neoplasms
Inflammation
Cytokines
2014
7 Citations (Scopus)

Associations between medication use and homocysteine levels in an older population, and potential mediation by vitamin B12 and folate: data from the B-PROOF study

Ham, A. C., Enneman, A. W., van Dijk, S. C., van Wijngaarden, J. P., van der Zwaluw, N. L., Brouwer, E. M., Dhonukshe-Rutten, R. A. M., de Groot, C. P. G. M. & Witkamp, R. F., 2014, In : Drugs & Aging. 31, 8, p. 611-621

Research output: Contribution to journalArticleAcademicpeer-review

Vitamin B Complex
Osteoporotic Fractures
Homocysteine
Vitamin B 12
Folic Acid
23 Citations (Scopus)

Cross-Species Comparison of Genes Related to Nutrient Sensing Mechanisms Expressed along the Intestine

van der Wielen, N., van Avesaat, M., de Wit, N. J. W., Vogels, J., Troost, F., Masclee, A., Koopmans, S. J., van der Meulen, J., Boekschoten, M. V., Müller, M. R., Hendriks, H. F. J., Witkamp, R. F. & Meijerink, J., 2014, In : PLoS ONE. 9, 9, 9 p., e107531.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Nutrients
Intestines
intestines
Swine
Genes
13 Citations (Scopus)

Hypothalamic food intake regulation in a cancer-cachectic mouse model

Dwarkasing, J. T., van Dijk, M., Dijk, F. J., Boekschoten, M. V., Faber, J., Argiles, J. M., Laviano, A., Müller, M. R., Witkamp, R. F. & van Norren, K., 2014, In : Journal of cachexia, sarcopenia and muscle. 5, 2, p. 159-169

Research output: Contribution to journalArticleAcademicpeer-review

Appetite Regulation
Eating
Neoplasms
Serotonin
Hypothalamus
41 Citations (Scopus)

Medication-Related Fall Incidents in an Older, Ambulant Population: The B-PROOF Study

Ham, A. C., Swart, K. M. A., Enneman, A. W., van Dijk, S. C., Araghi, S. O., van Wijngaarden, J. P., van der Zwaluw, N. L., Brouwer, E. M., Dhonukshe-Rutten, R. A. M., van Schoor, N. M., van der Cammen, T. J. M., Lips, P., Uitterlinden, A. G., Witkamp, R. F., Stricker, B. H., van der Velde, N. & de Groot, C. P. G. M., 2014, In : Drugs & Aging. 31, 12, p. 917-927

Research output: Contribution to journalArticleAcademicpeer-review

Vitamin B Complex
Osteoporotic Fractures
Confidence Intervals
Independent Living
Population
6 Citations (Scopus)

Palmitoylethanolamide (PEA)—‘Promiscuous’ anti-inflammatory and analgesic molecule at the interface between nutrition and pharma

Keppel Hesselink, J. M., Kopsky, D. J. & Witkamp, R. F., 2014, In : PharmaNutrition. 2, 1, p. 19-25

Research output: Contribution to journalArticleAcademicpeer-review

peanut meal
central nervous system diseases
Non-Steroidal Anti-Inflammatory Agents
analgesics
pharmacology
11 Citations (Scopus)

Steviol glycoside rebaudioside A induces glucagon-like peptide-1 and peptide YY release in a porcine ex vivo intestinal model

Ripken, D., van der Wielen, N., Wortelboer, H. M., Meijerink, J., Witkamp, R. F. & Hendriks, H. F., 2014, In : Journal of Agricultural and Food Chemistry. 62, 33, p. 8365-8370 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

peptide YY
steviol
Peptide YY
glucagon-like peptide 1
Glucagon-Like Peptide 1
8 Citations (Scopus)

The Biphasic Effects of Moderate Alcohol Consumption with a Meal on Ambiance-Induced Mood and Autonomic Nervous System Balance: A Randomized Crossover Trial

Schrieks, I. C., Stafleu, A., Kallen, V. L., Grootjen, M., Witkamp, R. F. & Hendriks, H. F. J., 2014, In : PLoS ONE. 9, 1, e86199.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
autonomic nervous system
Autonomic Nervous System
Neurology
emotions
meals (menu)
2013
47 Citations (Scopus)
Sambucus
Rubus
Fruits
anti-inflammatory activity
Italy
23 Citations (Scopus)

Liquid chromatography–tandem mass spectrometry analysis of free and esterified fatty acid N-acyl ethanolamines in plasma and blood cells

Balvers, M. G. J., Wortelboer, H. M., Witkamp, R. F. & Verhoeckx, K. C. M., 2013, In : Analytical Biochemistry. 434, 2, p. 275-283

Research output: Contribution to journalArticleAcademicpeer-review

Ethanolamines
Liquid chromatography
Tandem Mass Spectrometry
Plasma Cells
Nonesterified Fatty Acids
24 Citations (Scopus)

Measurement of palmitoylethanolamide and other N-acylethanolamines during physiological and pathological conditions

Balvers, M. G. J., Verhoeckx, K. C. M., Meijerink, J., Wortelboer, H. M. & Witkamp, R. F., 2013, In : CNS & Neurological Disorders. 12, 1, p. 26-33

Research output: Contribution to journalArticleAcademicpeer-review

Ethanolamines
amidase
palmidrol
N-acylethanolamines
Physiological Phenomena
23 Citations (Scopus)

Palmitoylethanolamide: A Natural Body-Own Anti-Inflammatory Agent, Effective and Safe against Influenza and Common Cold

Keppel Hesselink, J. M., de Boer, T. & Witkamp, R. F., 2013, In : International Journal of Inflammation. 2013, 8 p., 151028.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Common Cold
Human Influenza
Anti-Inflammatory Agents
palmidrol
Neuralgia
79 Citations (Scopus)

Vitamin D. Do we get enough?

Brouwer, E. M., Bischoff-Ferrari, H. A., Bouillon, R., Feskens, E. J. M., Gallagher, C. J., Hypponen, E., Llewellyn, D., Stoecklin, E., Dierkes, J., Kies, A. K., Kok, F. J., Lamberg-Allardt, C., Moser, U., Pilz, S., Saris, W. H. M., van Schoor, N. M., Weber, P., Witkamp, R. F., Zittermann, A. & de Groot, C. P. G. M., 2013, In : Osteoporis International. 24, 5, p. 1567-1577

Research output: Contribution to journalArticleAcademicpeer-review

Vitamin D
Health
2012
18 Citations (Scopus)

Effects of Long- and Short-Chain Fatty Acids on the Release of Gastrointestinal Hormones using an ex Vivo Porcine Intestinal Tissue Model

Voortman, T., Hendriks, H. F. J., Witkamp, R. F. & Wortelboer, H. M., 2012, In : Journal of Agricultural and Food Chemistry. 60, 36, p. 9035-9042 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

gastrointestinal hormones
Gastrointestinal Hormones
Volatile Fatty Acids
long chain fatty acids
short chain fatty acids
64 Citations (Scopus)

Fish oil and inflammatory status alter the n-3 to n-6 balance of the endocannabinoid and oxylipin metabolomes in mouse plasma and tissues

Balvers, M. G. J., Verhoeckx, K. C. M., Bijlsma, S., Rubingh, C. M., Meijerink, J., Wortelboer, H. M. & Witkamp, R. F., 2012, In : Metabolomics. 8, 6, p. 1130-1147

Research output: Contribution to journalArticleAcademicpeer-review

Oxylipins
Endocannabinoids
Metabolome
Fish Oils
Tissue
11 Citations (Scopus)

Lipidomics reveals multiple pathway effects of a multi components preparation on lipd biochemistry in ApoeE*3Leiden.CETP mice

Wei, H., Hu, C., Wang, M., van den Hoek, A. M., Reijmers, T. H., Wopereis, S., Bouwman, J., Ramaker, R., Korthout, H. A. A. J., Vennik, M., Hankemeier, T., Havekes, L. M., Witkamp, R. F., Verheij, E. R., Xu, G. & de Greef, J., 2012, In : PLoS ONE. 7, 1, e30332.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Biochemistry
rimonabant
metabolic syndrome
biochemistry
mice
18 Citations (Scopus)

Moderate alcohol consumption alters both leucocyte gene expression profiles and circulating proteins related to immune response and lipid metabolism in men

Joosten, M. M., van Erk, M. J., Pellis, E. P. M., Witkamp, R. F. & Hendriks, H. F. J., 2012, In : British Journal of Nutrition. 108, 4, p. 620-627

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Lipid Metabolism
Transcriptome
Alcohol Drinking
Leukocytes
Proteins
36 Citations (Scopus)

Time-dependent effect of in vivo inflammation on eicosanoid and endocannabinoid levels in plasma, liver, ileum and adipose tissue in C57BL/6 mice fed a fish-oil diet

Balvers, M. G. J., Verhoeckx, K. C. M., Meijerink, J., Bijlsma, S., Rubingh, C. M., Wortelboer, H. M. & Witkamp, R. F., 2012, In : International Immunopharmacology. 13, 2, p. 204-214

Research output: Contribution to journalArticleAcademicpeer-review

Endocannabinoids
Eicosanoids
Fish Oils
Inbred C57BL Mouse
Ileum
2011
47 Citations (Scopus)

26th Hohenheim Concensus Conference, September 11, 2010 Scientific substantiation of health claims: Evidence-based nutrition

Biesalski, H. K., Aggett, P. J., Anton, R., Bernstein, P. S., Blumberg, J., Heaney, R. P., Henry, J., Nolan, J. M., Richardson, D. P., van Ommen, B., Witkamp, R. F., Rijkers, G. T. & Zollner, I., 2011, In : Nutrition. 27, 10, p. S1-S20

Research output: Contribution to journalArticleAcademicpeer-review

Glycemic Index
Micronutrients
Health
Probiotics
Macular Degeneration
17 Citations (Scopus)

Alterations in total and high-molecular-weight adiponectin after 3 weeks of moderate alcohol consumption in premenopausal women

Joosten, M. M., Witkamp, R. F. & Hendriks, H. F. J., 2011, In : Metabolism : Clinical and Experimental. 60, 8, p. 1058-1063

Research output: Contribution to journalArticleAcademicpeer-review

Adiponectin
Alcohol Drinking
Molecular Weight
Alcohols
Glucose
27 Citations (Scopus)

A standardised approach towards PROving the efficacy of foods and Food Constituents for Health CLAIMs (PROCLAIM: providing guidance

Gallagher, A. M., Meijer, G. W., Richardson, D. P., Rondeau, V., Skarp, M., Stasse-Wolthuis, M., Tweedie, G. C. & Witkamp, R. F., 2011, In : British Journal of Nutrition. 106, Suppl. 2, p. S16-S28

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Food
Health
Research
Food Industry
Insurance Benefits
16 Citations (Scopus)
Colostrum
Athletes
Exercise
Powders
Milk
42 Citations (Scopus)

Presence, formation and putative biological activities of N-acyl serotonins, a novel class of fatty-acid derived mediators in the intestinal tract

Verhoeckx, K. C. M., Voortman, T., Balvers, M. G. J., Hendriks, H. F. J., Wortelboer, H. M. & Witkamp, R. F., 2011, In : Biochimica et Biophysica Acta. Molecular and Cell Biology of Lipids. 1811, 10, p. 578-586

Research output: Contribution to journalArticleAcademicpeer-review

Serotonin
Fatty Acids
Neurotransmitter Agents
Ethanolamines
Diet
49 Citations (Scopus)
Open Access
Fish Oils
Chemokine CCL2
Peritoneal Macrophages
Inflammation
Omega-3 Fatty Acids
2010
8 Citations (Scopus)

Absorption, distribution and biliary excretion of cafestol, a potent cholesterol elevating compound in unfiltered coffees in mice

van Cruchten, S. T. J., de Waart, D. R., Kunne, C., Hooiveld, G. J. E. J., Boekschoten, M. V., Katan, M. B., Oude Elferink, R. P. J. & Witkamp, R. F., 2010, In : Drug Metabolism and Disposition. 38, 4, p. 635-640

Research output: Contribution to journalArticleAcademicpeer-review

Coffee
Cholesterol
Bile
Glucuronides
Portal Vein

Arts en diëtist samen verantwoordelijk

Vasse, E., Wijnans-Aerts, G. J. M., Witkamp, R. F. & van Binsbergen, J. J., 2010, In : Nederlands Tijdschrift voor Voeding en Dietetiek. 65, 4, p. 7-10

Research output: Contribution to journalArticleAcademicpeer-review

69 Citations (Scopus)

Docosahexaenoic acid and eicosapentaenoic acid are converted by 3T3-L1 adipocytes to N-acyl ethanolamines with anti-inflammatory properties

Balvers, M. G. J., Verhoeckx, K. C. M., Plastina, P., Wortelboer, H. M., Meijerink, J. & Witkamp, R. F., 2010, In : Biochimica et Biophysica Acta. Molecular and Cell Biology of Lipids. 1801, 10, p. 1107-1114

Research output: Contribution to journalArticleAcademicpeer-review

Ethanolamines
Ethanolamine
Eicosapentaenoic Acid
Docosahexaenoic Acids
Adipocytes

Interacties tussen geneesmiddelen en voeding: geneesmiddelen en de voedingsstatus

Witkamp, R. F., 2010, In : Patient Care. 33, 4, p. 28-32

Research output: Contribution to journalArticleProfessional

Interacties tussen geneesmiddelen en voeding: updat over de invloed van voeding op geneesmiddelen

Witkamp, R. F., 2010, In : Patient Care. 33, 4, p. 24-27

Research output: Contribution to journalArticleProfessional

Interacties voeding en geneesmiddelen bij chronische hart- en vaatziekten: De diëtist is aan zet:

Vasse, E., Wijnans-Aerts, G. J. M., Witkamp, R. F. & van Binsbergen, J. J., 2010, In : Nederlands Tijdschrift voor Voeding en Dietetiek. 65, p. 7-10

Research output: Contribution to journalArticleProfessional

36 Citations (Scopus)

Plasma anandamide and other N-acylethanolamines are correlated with their corresponding free fatty acid levels under both fasting and non-fasting conditions in women

Joosten, M. M., Balvers, M. G. J., Verhoeckx, K. C. M., Hendriks, H. F. J. & Witkamp, R. F., 2010, In : Nutrition & Metabolism. 7, 6 p., 49.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Nonesterified Fatty Acids
Fasting
Fatty Acids
Appetite Regulation
Lunch

Samenwerkingsproject van RIVM, TNO en Wageningen Universiteit / Gezondheidseffecten van groenten en fruit

Hendriks, H., Verhagen, H., Büchner, F., van Duijnhoven, F. J. B., Witkamp, R. F., Peppelenbos, H. & Woltering, E. J., 2010, In : Voeding Nu. 12, 3, p. 26-28

Research output: Contribution to journalArticleProfessional

8 Citations (Scopus)

Short-term oral exposure to white wine transiently lowers serum free fatty acids

Joosten, M. M., de Graaf, C., Rietman, A., Witkamp, R. F. & Hendriks, H. F. J., 2010, In : Appetite. 55, 1, p. 124-129

Research output: Contribution to journalArticleAcademicpeer-review

Wine
Nonesterified Fatty Acids
Alcohols
Serum
Head
16 Citations (Scopus)
Coffee
Epoxidation
Transcription
Genes
Aflatoxin B1
2009
61 Citations (Scopus)
Plasma (human)
Endocannabinoids
Liquid chromatography
Tandem Mass Spectrometry
Liquid Chromatography
4 Citations (Scopus)

Herbal products: Marketing strategies and legislation

Hooyenga, P. A., Witkamp, R. F. & Groen, K. P., 2009, In : International Journal of Green Pharmacy. 3, 4, p. 270-276

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
European Union
Marketing
Legislation
Jurisprudence
Dietary Supplements
21 Citations (Scopus)

Selective Synthesis of Unsaturated N-Acylethanolamines by Lipase-Catalyzed N-Acylation of Ethanolamine with Unsaturated Fatty Acids

Plastina, P., Vincken, J. P., Gruppen, H., Witkamp, R. F. & Gabriele, B., 2009, In : Letters in Organic Chemistry. 6, 6, p. 444-447

Research output: Contribution to journalArticleAcademicpeer-review

Acylation
Ethanolamine
Hexanes
Lipase
Unsaturated Fatty Acids
39 Citations (Scopus)
Humulus lupulus
Humulus
Chemokine CCL2
Macrophages
hops
2008

De verrassende X-factor van klinische voeding

de Vries, J. H. M., Witkamp, R. F. & Schols, A. M., 2008, In : Voeding Nu. 10, 12, p. 26-27

Research output: Contribution to journalArticleProfessional

2006
23 Citations (Scopus)

Beta-adrenergic receptor agonists induce the release of granulocyte chemotactic protein-2, oncostatin M, and vascular endothelial growth factor from macrophages

Verhoeckx, K. C. M., Doornbos, R. P., Witkamp, R. F., de Greef, J. & Rodenburg, R. J. T., 2006, In : International Immunopharmacology. 6, 1, p. 1-7

Research output: Contribution to journalArticleAcademicpeer-review

Chemokine CXCL6
Oncostatin M
Adrenergic beta-Agonists
Vascular Endothelial Growth Factor A
Macrophages
33 Citations (Scopus)

Unheated Cannabis sativa extracts and its major compound THC-acid have potential immuno-modulating properties not mediated bu CB1 en CB2 receptor coupled pathways

Verhoeckx, K. C. M., Korthout, H. A. A. J., van Meeteren-Kreikamp, A. P., Ehlert, K. A., Wang, M., de Greef, J., Rodenburg, R. J. T. & Witkamp, R. F., 2006, In : International Immunopharmacology. 6, 4, p. 656-665

Research output: Contribution to journalArticleAcademicpeer-review

Cannabinoid Receptor CB2
Dronabinol
Cannabis
Acids
Tumor Necrosis Factor-alpha
2001
60 Citations (Scopus)

Development of an androgen reporter gene assay (AR-LUX) utilizing a human cell line with an endogenously regulated androgen receptor

Blankvoort, B. M. G., de Groene, E. M., van Meeteren-Kreikamp, A. P., Witkamp, R. F., Rodenburg, R. J. T. & Aarts, J. M. M. J. G., 2001, In : Analytical Biochemistry. 298, p. 93-102

Research output: Contribution to journalArticleAcademicpeer-review

Androgen Receptors
Reporter Genes
Androgens
Assays
Genes
1998
31 Citations (Scopus)

Multi-laboratory study of the analysis and kinetics of stanozolol and its metabolites in treated calves

de Brabander, H. F., de Wasch, K., van Ginkel, L. A., Sterk, S. S., Blokland, M. H., Delahaut, P., Taillieu, X., Dubois, M., Arts, C. J. M., van Baak, M. J., Gramberg, L. G., Schilt, R., van Bennekom, E. O., Courtheyn, D., Vercammen, J. & Witkamp, R. F., 1998, In : The Analyst. 123, p. 2599-2604

Research output: Contribution to journalArticleAcademicpeer-review

1995
27 Citations (Scopus)

Infection (Actinobacillus pleuropneumoniae)-medicated suppression of oxidative hepatic drug metabolism and cytochrome P 4503A mRNA levels in pigs

Monshouwer, M., Witkamp, R. F., Nijmeijer, S. M., van Leengoed, L. A. M. G. & van Miert, A. S. J. P. A. M., 1995, In : Drug Metabolism and Disposition. 23, p. 44-47

Research output: Contribution to journalArticleAcademicpeer-review