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Research Output 1995 2019

Abstract

De associatie tussen medicijngebruik en het homocysteïnegehalte in een Nederlandse populatie ouderen.

van Wijngaarden, J. P., Schoufour, J. D., Dhonukshe-Rutten, R. A. M., de Groot, C. P. G. M., Janse, A. & Witkamp, R. F., 2011, Geriatriedagen Den Bosch, 3-4 februari 2011. Den Bosch, p. 151

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

Open Access

Een cross-sectionele studie naar de associatie tussen medicijngebruik en nutriëntenstatus bij een poliklinische geriatrie-populatie.

Schoufour, J. D., van Wijngaarden, J. P., Dhonukshe-Rutten, R. A. M., de Groot, C. P. G. M., Witkamp, R. F. & Janse, A., 2011, Geriatriedagen Den Bosch, 3-4 februari. Den Bosch, p. 142

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

Open Access

Intensive Exercise Hampers the Postprandial Citrulline Bioavailability Following Casein Bolus Feeding

Janssen Duijghuijsen, L., Mensink, M. G. J., Witkamp, R. F., Keijer, J., Wichers, H. J., Luiking, Y. & van Norren, K., 2014, Abstracts of the 36th ESPEN Congress. Elsevier, Vol. 33. p. S11-S12

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

Open Access
Citrulline
Lactulose
Rhamnose
Caseins
Biological Availability

Interplay between macrophages and adipocytes: stimulation of secretion of adipokines and the role of endocannabinoids

Wortelboer, H. M., Lancee, C. A. A., Meijerink, J. & Witkamp, R. F., 2008, In : International Journal of Obesity. 32, S1, p. S64

Research output: Contribution to journalAbstractAcademic

Endocannabinoids
Adipokines
Adipocytes
Lipopolysaccharides
Macrophages

Intestinal epithelial integrity depends on mitochondrial energy production

Janssen Duijghuijsen, L. M., Grefte, S., van Norren, K., de Boer, V. C. J., van Dartel, D. A. M., Witkamp, R. F., Wichers, H. J. & Keijer, J., 24 Nov 2016.

Research output: Contribution to conferenceAbstractAcademic

Is neural regulation of satiation more important than hormonal regulation of satiation?

Ripken, D., Wielen, N., van der Meulen, J., Schuurman, T., Witkamp, R. F., Hendriks, H. & Koopmans, S. J., 2013, In : Obesity Facts. 6, Suppl. 1, p. 5-5 T1:RS1.3.

Research output: Contribution to journalAbstractAcademic

Open Access

Is use of medication associated with blood levels of micronutrients? A cross-sectional study of a geriatric hospital population

van Orten-Luiten, A. C. B., Janse, A., Dhonukshe-Rutten, R. A. M. & Witkamp, R. F., 2013, Proceedings of the 1st National Congress on Nutritional Medicine of the Dutch Nutraceutical Association. Bast, A., Brouns, F., Dekker, W., Feskens, E. J. M. & Kardinaal, A. (eds.). Karger, Vol. 62. p. 154-154

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

Medication-related fall incidents in an older, ambulant population: the B-PROOF study

Ham, A. C., Swart, K. M. A., Enneman, A. W., van Dijk, S. C., Oliai Araghi, S., van Wijngaarden, J. P., van der Zwaluw, N. L., Brouwer, E. M., Dhonukshe-Rutten, R. A. M., van Schoor, N. M., van der Cammen, T. J. M., Lips, P., de Groot, C. P. G. M., Uitterlinden, A. G., Witkamp, R. F., Stricker, B. H. C. & van der Velde, N., 2014, Book of abstracts of the 10th International Congress of the European Union Geriatric Medicine Society - Geriatric Medicine Crossing Borders. Michel, J. P. (ed.). European Union Geriatric Medicine Society, Vol. 5. p. S50-S50

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

The effect of exercise on intestinal integrity and protein permeability

Janssen Duijghuijsen, L. M., Keijer, J., Mensink, M. R., Bastiaan-Net, S., Mes, J. J., Luiking, Y., Wichers, H. J., Witkamp, R. F. & van Norren, K., 2018.

Research output: Contribution to conferenceAbstractAcademic

Article
47 Citations (Scopus)

26th Hohenheim Concensus Conference, September 11, 2010 Scientific substantiation of health claims: Evidence-based nutrition

Biesalski, H. K., Aggett, P. J., Anton, R., Bernstein, P. S., Blumberg, J., Heaney, R. P., Henry, J., Nolan, J. M., Richardson, D. P., van Ommen, B., Witkamp, R. F., Rijkers, G. T. & Zollner, I., 2011, In : Nutrition. 27, 10, p. S1-S20

Research output: Contribution to journalArticleAcademicpeer-review

Glycemic Index
Micronutrients
Health
Probiotics
Macular Degeneration
9 Citations (Scopus)

Absorption, distribution and biliary excretion of cafestol, a potent cholesterol elevating compound in unfiltered coffees in mice

van Cruchten, S. T. J., de Waart, D. R., Kunne, C., Hooiveld, G. J. E. J., Boekschoten, M. V., Katan, M. B., Oude Elferink, R. P. J. & Witkamp, R. F., 2010, In : Drug Metabolism and Disposition. 38, 4, p. 635-640

Research output: Contribution to journalArticleAcademicpeer-review

Coffee
Cholesterol
Bile
Glucuronides
Portal Vein
4 Citations (Scopus)

Adaptation of exercise-induced stress in well-trained healthy young men

Janssen Duijghuijsen, L. M., Keijer, J., Mensink, M. R., Lenaerts, K., Ridder, L. O., Nierkens, S., Kartaram, S., Verschuren, M. C. M., Pieters, R., Bas, R., Witkamp, R. F., Wichers, H. J. & van Norren, K., 2017, In : Experimental Physiology. 102, 1, p. 86-99

Research output: Contribution to journalArticleAcademicpeer-review

Exercise
Lactulose
Rhamnose
Energy Metabolism
Urine

A Diet Rich in Fish Oil and Leucine Ameliorates Hypercalcemia in Tumour-Induced Cachectic Mice

Plas, R. L. C., Poland, M., Faber, J., Argilès, J., van Dijk, M., Laviano, A., Meijerink, J., Witkamp, R. F., van Helvoort, A. & van Norren, K., 9 Oct 2019, In : International Journal of Molecular Sciences. 20, 20, 4978.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
diets
leucine
Fish Oils
fishes
Hypercalcemia
17 Citations (Scopus)

Alterations in total and high-molecular-weight adiponectin after 3 weeks of moderate alcohol consumption in premenopausal women

Joosten, M. M., Witkamp, R. F. & Hendriks, H. F. J., 2011, In : Metabolism : Clinical and Experimental. 60, 8, p. 1058-1063

Research output: Contribution to journalArticleAcademicpeer-review

Adiponectin
Alcohol Drinking
Molecular Weight
Weights and Measures
Alcohols

Anti-inflammatory nutrition with high protein attenuates cardiac and skeletal muscle alterations in a pulmonary arterial hypertension model

Vinke, P., Bowen, T. S., Boekschoten, M. V., Witkamp, R. F., Adams, V. & van Norren, K., 15 Jul 2019, In : Scientific Reports. 9, 1, 10160.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Monocrotaline
Pulmonary Hypertension
Myocardium
Skeletal Muscle
Anti-Inflammatory Agents

Arts en diëtist samen verantwoordelijk

Vasse, E., Wijnans-Aerts, G. J. M., Witkamp, R. F. & van Binsbergen, J. J., 2010, In : Nederlands Tijdschrift voor Voeding en Dietetiek. 65, 4, p. 7-10

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Associations between medication use and homocysteine levels in an older population, and potential mediation by vitamin B12 and folate: data from the B-PROOF study

Ham, A. C., Enneman, A. W., van Dijk, S. C., van Wijngaarden, J. P., van der Zwaluw, N. L., Brouwer, E. M., Dhonukshe-Rutten, R. A. M., de Groot, C. P. G. M. & Witkamp, R. F., 2014, In : Drugs & Aging. 31, 8, p. 611-621

Research output: Contribution to journalArticleAcademicpeer-review

Vitamin B Complex
Osteoporotic Fractures
Homocysteine
Vitamin B 12
Folic Acid
1 Citation (Scopus)

Associations of hyperosmolar medications administered via nasogastric or nasoduodenal tubes and feeding adequacy, food intolerance and gastrointestinal complications amongst critically ill patients: A retrospective study

Wesselink, E., Koekkoek, K. W. A. C., Looijen, M., van Blokland, D. A., Witkamp, R. F. & van Zanten, A. R. H., Jun 2018, In : Clinical Nutrition ESPEN. 25, p. 78-86

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Enteral Nutrition
Critical Illness
Retrospective Studies
Food
Diarrhea
27 Citations (Scopus)

A standardised approach towards PROving the efficacy of foods and Food Constituents for Health CLAIMs (PROCLAIM: providing guidance

Gallagher, A. M., Meijer, G. W., Richardson, D. P., Rondeau, V., Skarp, M., Stasse-Wolthuis, M., Tweedie, G. C. & Witkamp, R. F., 2011, In : British Journal of Nutrition. 106, Suppl. 2, p. S16-S28

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Food
Health
Research
Food Industry
Insurance Benefits
23 Citations (Scopus)

Behavioural changes are a major contributing factor in the reduction of sarcopenia in caloric-restricted ageing mice

van Norren, K., Rusli, F., van Dijk, M., Lute, C., Nagel, J. C., Dijk, F. J., Dwarkasing, J. T., Boekschoten, M. V., Luiking, Y., Witkamp, R. F., Müller, M. R. & Steegenga, W. T., 2015, In : Journal of cachexia, sarcopenia and muscle. 6, 3, p. 253-268

Research output: Contribution to journalArticleAcademicpeer-review

Sarcopenia
Caloric Restriction
Muscles
Diet
Rodentia
23 Citations (Scopus)

Beta-adrenergic receptor agonists induce the release of granulocyte chemotactic protein-2, oncostatin M, and vascular endothelial growth factor from macrophages

Verhoeckx, K. C. M., Doornbos, R. P., Witkamp, R. F., de Greef, J. & Rodenburg, R. J. T., 2006, In : International Immunopharmacology. 6, 1, p. 1-7

Research output: Contribution to journalArticleAcademicpeer-review

Chemokine CXCL6
Oncostatin M
Adrenergic beta-Agonists
Vascular Endothelial Growth Factor A
Macrophages
5 Citations (Scopus)

Beta-blocker use and fall risk in older individuals: Original results from two studies with meta-analysis

Ham, A. C., van Dijk, S. C., Swart, K. M. A., Enneman, A. W., van der Zwaluw, N. L., Brouwer-Brolsma, E. M., van Schoor, N. M., Zillikens, M. C., Lips, P., de Groot, L. C. P. G. M., Hofman, A., Witkamp, R. F., Uitterlinden, A. G., Stricker, B. H. & van der Velde, N., 2017, In : British Journal of Clinical Pharmacology. 83, 10, p. 2292-2302

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Meta-Analysis
Cytochrome P-450 CYP2D6
Solubility
Odds Ratio
Confidence Intervals
16 Citations (Scopus)
Colostrum
Athletes
Exercise
Powders
Milk
2 Citations (Scopus)
Open Access
Microfluidics
HEK293 Cells
G-Protein-Coupled Receptors
calcium
Calcium
2 Citations (Scopus)

Capsaicin analogues derived from n-3 polyunsaturated fatty acids (PUFAs) reduce inflammatory activity of macrophages and stimulate insulin secretion by β-cells in vitro

Cione, E., Plastina, P., Pingitore, A., Perri, M., Caroleo, M. C., Fazio, A., Witkamp, R. & Meijerink, J., 1 Apr 2019, In : Nutrients. 11, 4, 915.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
capsaicin
long chain polyunsaturated fatty acids
insulin secretion
Capsaicin
Omega-3 Fatty Acids
3 Citations (Scopus)

Changes in iron metabolism during prolonged repeated walking exercise in middle-aged men and women

Terink, R., ten Haaf, D., Bongers, C. W. G., Balvers, M. G. J., Witkamp, R. F., Mensink, M., Eijsvogels, T. M. H., Klein Gunnewiek, J. M. T. & Hopman, M. T. E., Nov 2018, In : European Journal of Applied Physiology. 118, 11, p. 2349–2357

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Walking
Iron
Exercise
Haptoglobins
Ferritins
11 Citations (Scopus)

Cholecystokinin regulates satiation idependently of the abdominal vagal nerve in a pig model of total subdiaphragmatic vagotomy

Ripken, D., van der Wielen, N., van der Meulen, J., Schuurman, T., Witkamp, R. F., Hendriks, H. F. J. & Koopmans, S. J., 2015, In : Physiology and Behavior. 139, 2015, p. 167-176

Research output: Contribution to journalArticleAcademicpeer-review

Satiation
Glucagon-Like Peptide 1
Vagotomy
Cholecystokinin
Swine
48 Citations (Scopus)
Sambucus
Rubus
Fruits
anti-inflammatory activity
Italy
23 Citations (Scopus)

Cross-Species Comparison of Genes Related to Nutrient Sensing Mechanisms Expressed along the Intestine

van der Wielen, N., van Avesaat, M., de Wit, N. J. W., Vogels, J., Troost, F., Masclee, A., Koopmans, S. J., van der Meulen, J., Boekschoten, M. V., Müller, M. R., Hendriks, H. F. J., Witkamp, R. F. & Meijerink, J., 2014, In : PLoS ONE. 9, 9, 9 p., e107531.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Nutrients
Intestines
intestines
Swine
Genes
6 Citations (Scopus)

CYP2C9 genotypes modify benzodiazepine-related fall risk: Original results from three studies with meta-analysis

Ham, A. C., Ziere, G., Broer, L., van Wijngaarden, J. P., van der Zwaluw, N. L., Brouwer, E. M., Dhonukshe-Rutten, R. A. M., de Groot, C. P. G. M. & Witkamp, R. F., 2017, In : Journal of the American Medical Directors Association. 18, 1, p. 88.e1-88.e15

Research output: Contribution to journalArticleAcademicpeer-review

Benzodiazepines
Meta-Analysis
Genotype
Alleles
Confidence Intervals
2 Citations (Scopus)
Athletes
Magnesium
Exercise
Athletic Performance
Research
7 Citations (Scopus)

Detection of peanut allergen in human blood after consumption of peanuts is skewed by endogenous immunoglobulins

Janssen Duijghuijsen, L. M., Wichers, H. J., van Norren, K., Keijer, J., Baumert, J. L., De Jong, G. A. H., Witkamp, R. F. & Koppelman, S. J., 2017, In : Journal of Immunological Methods. 440, p. 52-57

Research output: Contribution to journalArticleAcademicpeer-review

Allergens
Immunoglobulins
Immunoglobulin G
Serum
Eating
62 Citations (Scopus)
Plasma (human)
Endocannabinoids
Liquid chromatography
Tandem Mass Spectrometry
Liquid Chromatography
61 Citations (Scopus)

Development of an androgen reporter gene assay (AR-LUX) utilizing a human cell line with an endogenously regulated androgen receptor

Blankvoort, B. M. G., de Groene, E. M., van Meeteren-Kreikamp, A. P., Witkamp, R. F., Rodenburg, R. J. T. & Aarts, J. M. M. J. G., 2001, In : Analytical Biochemistry. 298, p. 93-102

Research output: Contribution to journalArticleAcademicpeer-review

Androgen Receptors
Reporter Genes
Androgens
Assays
Genes

De verrassende X-factor van klinische voeding

de Vries, J. H. M., Witkamp, R. F. & Schols, A. M., 2008, In : Voeding Nu. 10, 12, p. 26-27

Research output: Contribution to journalArticleProfessional

19 Citations (Scopus)
Serotonin
Eating
Neuropeptide Y
Neoplasms
Lewis Lung Carcinoma
70 Citations (Scopus)

Docosahexaenoic acid and eicosapentaenoic acid are converted by 3T3-L1 adipocytes to N-acyl ethanolamines with anti-inflammatory properties

Balvers, M. G. J., Verhoeckx, K. C. M., Plastina, P., Wortelboer, H. M., Meijerink, J. & Witkamp, R. F., 2010, In : Biochimica et Biophysica Acta. Molecular and Cell Biology of Lipids. 1801, 10, p. 1107-1114

Research output: Contribution to journalArticleAcademicpeer-review

Ethanolamines
Ethanolamine
Eicosapentaenoic Acid
Docosahexaenoic Acids
Adipocytes
7 Citations (Scopus)
Interleukin-17
Omega-3 Fatty Acids
Serotonin
Anti-Inflammatory Agents
Macrophages
8 Citations (Scopus)
Interleukin-17
Blood Cells
Serotonin
Fatty Acids
Interleukin-23
1 Citation (Scopus)

Drug use is associated with lower plasma magnesium levels in geriatric outpatients; possible clinical relevance

van Orten-Luiten, A. C. B., Janse, A., Verspoor, E., Brouwer-Brolsma, E. M. & Witkamp, R. F., Dec 2019, In : Clinical Nutrition. 38, 6, p. 2668-2676

Research output: Contribution to journalArticleAcademicpeer-review

Geriatrics
Magnesium
Outpatients
Pharmaceutical Preparations
Polypharmacy
19 Citations (Scopus)

Effects of Long- and Short-Chain Fatty Acids on the Release of Gastrointestinal Hormones using an ex Vivo Porcine Intestinal Tissue Model

Voortman, T., Hendriks, H. F. J., Witkamp, R. F. & Wortelboer, H. M., 2012, In : Journal of Agricultural and Food Chemistry. 60, 36, p. 9035-9042 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

gastrointestinal hormones
Gastrointestinal Hormones
Volatile Fatty Acids
long chain fatty acids
short chain fatty acids
7 Citations (Scopus)

Effects of mood inductions by meal ambiance and moderate alcohol consumption on endocannabinoids and N-acylethanolamines in humans: A randomized crossover trial

Schrieks, I. C., Ripken, D., Stafleu, A., Witkamp, R. F. & Hendriks, H. F. J., 2015, In : PLoS ONE. 10, 5, 15 p., e0126421.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Endocannabinoids
emotions
sparkling wines
Alcohol Drinking
Cross-Over Studies
6 Citations (Scopus)

Endurance exercise increases intestinal uptake of the peanut allergen Ara h 6 after peanut consumption in humans

Janssen Duijghuijsen, L. M., Van Norren, K., Grefte, S., Koppelman, S. J., Lenaerts, K., Keijer, J., Witkamp, R. F. & Wichers, H. J., 2017, In : Nutrients. 9, 1, 84.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Lactulose
allergens
peanuts
lactulose
exercise
27 Citations (Scopus)

Fatty acids, endocannabinoids and inflammation

Witkamp, R., 2016, In : European Journal of Pharmacology. 785, p. 96-107

Research output: Contribution to journalArticleAcademicpeer-review

Endocannabinoids
Fatty Acids
Inflammation
Physiological Phenomena
Ligands
4 Citations (Scopus)

Feeding mitochondria: Potential role of nutritional components to improve critical illness convalescence

Wesselink, E., Koekkoek, W. A. C., Grefte, S., Witkamp, R. F. & van Zanten, A. R. H., Jun 2019, In : Clinical Nutrition. 38, 3, p. 982-995

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
coenzyme Q10
Micronutrients
Critical Illness
Mitochondria
Selenium
67 Citations (Scopus)

Fish oil and inflammatory status alter the n-3 to n-6 balance of the endocannabinoid and oxylipin metabolomes in mouse plasma and tissues

Balvers, M. G. J., Verhoeckx, K. C. M., Bijlsma, S., Rubingh, C. M., Meijerink, J., Wortelboer, H. M. & Witkamp, R. F., 2012, In : Metabolomics. 8, 6, p. 1130-1147

Research output: Contribution to journalArticleAcademicpeer-review

Oxylipins
Endocannabinoids
Metabolome
Fish Oils
Tissue
11 Citations (Scopus)

Fish oil LC-PUFAs do not affect blood coagulation parameters and bleeding manifestations: Analysis of 8 clinical studies with selected patient groups on omega-3-enriched medical nutrition

Jeansen, S., Witkamp, R. F., Garthoff, J. A., van Helvoort, A. & Calder, P. C., Jun 2018, In : Clinical Nutrition. 37, 3, p. 948-957

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Fish Oils
Omega-3 Fatty Acids
Blood Coagulation
Hemorrhage
Vulnerable Populations

Geneesmiddelgebruik, ondervoeding en deficiënties bij ouderen

van Orten-Luiten, A. C. B., Janse, A. & Witkamp, R. F., 2016, In : MFM- praktijkgerichte nascholing over farmacotherapie. editie 2

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Herbal products: Marketing strategies and legislation

Hooyenga, P. A., Witkamp, R. F. & Groen, K. P., 2009, In : International Journal of Green Pharmacy. 3, 4, p. 270-276

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
European Union
Marketing
Legislation
Jurisprudence
Dietary Supplements
13 Citations (Scopus)

Hypothalamic food intake regulation in a cancer-cachectic mouse model

Dwarkasing, J. T., van Dijk, M., Dijk, F. J., Boekschoten, M. V., Faber, J., Argiles, J. M., Laviano, A., Müller, M. R., Witkamp, R. F. & van Norren, K., 2014, In : Journal of cachexia, sarcopenia and muscle. 5, 2, p. 159-169

Research output: Contribution to journalArticleAcademicpeer-review

Appetite Regulation
Eating
Neoplasms
Serotonin
Hypothalamus