Raymond Staals

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Clustered Regularly Interspaced Short Palindromic Repeats Medicine & Life Sciences

CRISPR-Cas Systems Medicine & Life Sciences

Bacteriophages Medicine & Life Sciences

Immunity Medicine & Life Sciences

RNA Medicine & Life Sciences

Plasmids Medicine & Life Sciences

Thermus thermophilus Medicine & Life Sciences

Bacteria Medicine & Life Sciences

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Research Output 2012 2019

17 Article
1 Chapter

2 Citations (Scopus)

Bioinformatic evidence of widespread priming in type I and II CRISPR-Cas systems

Nicholson, T. J., Jackson, S. A., Croft, B. I., Staals, R. H. J., Fineran, P. C. & Brown, C. M., 7 May 2019, In : RNA Biology. 16, 4, p. 566-576

Research output: Contribution to journal › Article › Academic › peer-review

CRISPR-Cas Systems

Clustered Regularly Interspaced Short Palindromic Repeats

Computational Biology

Archaeal Viruses

Bacteriophages

2 Citations (Scopus)

Different genetic and morphological outcomes for phages targeted by single or multiple CRISPR-Cas spacers

Watson, B. N. J., Easingwood, R. A., Tong, B., Wolf, M., Salmond, G. P. C., Staals, R. H. J., Bostina, M. & Fineran, P. C., 25 Mar 2019, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 374, 1772, 20180090.

Research output: Contribution to journal › Article › Academic › peer-review

Clustered Regularly Interspaced Short Palindromic Repeats

Bacteriophages

bacteriophages

CRISPR-Cas Systems

Pectobacterium

3 Citations (Scopus)

Keeping crispr in check: diverse mechanisms of phage-encoded anti-crisprs

Trasanidou, D., Gerós, A. S., Mohanraju, P., Nieuwenweg, A. C., Nobrega, F. L. & Staals, R. H. J., 11 May 2019, In : FEMS Microbiology Letters. 366, 9

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Clustered Regularly Interspaced Short Palindromic Repeats

Bacteriophages

CRISPR-Cas Systems

Immune System

Immunity

Type I-F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity

Watson, B. N. J., Vercoe, R. B., Salmond, G. P. C., Westra, E. R., Staals, R. H. J. & Fineran, P. C., 1 Dec 2019, In : Nature Communications. 10, 1, 5526.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Clustered Regularly Interspaced Short Palindromic Repeats

Bacteriophages

immunity

infectious diseases

CRISPR-Cas Systems

19 Citations (Scopus)

CRISPR-cas-mediated phage resistance enhances horizontal gene transfer by transduction

Watson, B. N. J., Staals, R. H. J. & Fineran, P. C., 13 Feb 2018, In : mBio. 9, 1, e02406-17.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

Clustered Regularly Interspaced Short Palindromic Repeats

Horizontal Gene Transfer

Bacteriophages

Proteins

Genomic Islands

Datasets

RNA-targeting by the Type III-A CRISPR-Cas complex of Thermus thermophilus

Staals, R. (Creator), Zhu, Y. (Creator), Taylor, D. W. (Creator), Kornfeld, J. E. (Creator), Sharma, K. (Creator), Barendregt, A. (Creator), Koehorst, J. (Creator), Vlot, M. (Creator), Neupane, N. (Creator), Varossieau, K. (Creator), Sakamoto, K. (Creator), Suzuki, T. (Creator), Schaap, P. (Creator), Urlaub, H. (Creator), Heck, A. J. R. (Creator), Nogales, E. (Creator), Doudna, J. A. (Creator), Shinkai, A. (Creator), van der Oost, J. (Creator), Wageningen University, 9 Oct 2014

http://www.ebi.ac.uk/ena/data/view/PRJEB7461

Dataset