Linda Loonen-Jaklofsky

dr.ir.

    20082020
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    Research Output 2010 2019

    2019

    0046 - Organoids as models to study probiotics

    van der Hee, B., Loonen, L. M. P., Taverne, N., Taverne-Thiele, J. J., Smidt, H. & Wells, J. M., 19 Jun 2019, p. 57. 1 p.

    Research output: Contribution to conferenceAbstractAcademic

    Organoids
    Probiotics
    Cell Line
    Stem Cells
    Host-Pathogen Interactions
    7 Citations (Scopus)

    Polyphenols and Tryptophan Metabolites Activate the Aryl Hydrocarbon Receptor in an in vitro Model of Colonic Fermentation

    Koper, J. E. B., Loonen, L. M. P., Wells, J. M., Troise, A. D., Capuano, E. & Fogliano, V., 1 Feb 2019, In : Molecular Nutrition and Food Research. 63, 3, 1800722.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
    Luteolin
    Aryl Hydrocarbon Receptors
    Polyphenols
    luteolin
    Tryptophan
    2018
    16 Citations (Scopus)
    Open Access
    Organoids
    Swine
    Stem Cells
    Paneth Cells
    Tight Junctions
    2016
    12 Citations (Scopus)

    Identification of commensal species positively correlated with early stress responses to a compromised mucus barrier

    Sovran, B., Lu, P., Loonen, L. M. P., Hugenholtz, F., Belzer, C., Stolte, E. H., Boekschoten, M. V., Van Baarlen, P., Smidt, H., Kleerebezem, M., De Vos, P., Renes, I. B., Wells, J. M. & Dekker, J., 2016, In : Inflammatory Bowel Diseases. 22, 4, p. 826-840

    Research output: Contribution to journalArticleAcademicpeer-review

    Mucus
    Colitis
    Microbiota
    Gene Expression
    Bacteroides
    2015
    30 Citations (Scopus)

    IL-22-STAT3 Pathway Plays a Key Role in the Maintenance of Ileal Homeostasis in Mice Lacking Secreted Mucus Barrier

    Sovran, B., Loonen, L. M. P., Hugenholtz, F., Belzer, C., Kranenbarg-Stolte, H. H., Boekschoten, M. V., van Baarlen, P., Kleerebezem, M., de Vos, P., Dekker, J., Renes, I. B. & Wells, J. M., 2015, In : Inflammatory Bowel Diseases. 21, 3, p. 531-542

    Research output: Contribution to journalArticleAcademicpeer-review

    Mucus
    Homeostasis
    Maintenance
    Microbiota
    Ileum
    2014
    80 Citations (Scopus)

    REG3¿-deficient mice have altered mucus distribution and increased mucosal inflammatory responses to the microbiota and enteric pathogens in the ileum

    Loonen, L. M. P., Kranenbarg-Stolte, H. H., Jaklofsky, M. T. J., Meijerink, M., Dekker, J., van Baarlen, P. & Wells, J., 2014, In : Mucosal Immunology. 7, p. 939-947

    Research output: Contribution to journalArticleAcademicpeer-review

    Microbiota
    Mucus
    Ileum
    Gram-Positive Bacteria
    Infection
    2013

    RegIII proteins as gatekeepers of the intestinal epithelium

    Loonen, L. M. P., 2013, S.l.: s.n.. 205 p.

    Research output: Thesisinternal PhD, WU

    Open Access
    Intestinal Mucosa
    Salmonella enteritidis
    Mucins
    Colitis
    Proteins
    2012
    50 Citations (Scopus)

    Intestinally secreted C-type lectin Reg3b attenuates salmonellosis but not listeriosis in mice

    van Ampting, M. T. J., Loonen, L. M. P., Schonewille, A. J., Konings, I., Vink, C., Iovanna, J., Chamaillard, M., Dekker, J., van der Meer, R., Wells, J. & Bovee-Oudenhoven, I. M. J., 2012, In : Infection and Immunity. 80, 3, p. 1115-1120

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
    C-Type Lectins
    Listeriosis
    Salmonella Infections
    Listeria
    Knockout Mice
    40 Citations (Scopus)

    Mucin muc2 deficiency and weaning influences the expression of the innate defense genes reg3ß, reg3¿ and angiogenin-4

    Burger-van Paassen, N., Loonen, L. M. P., Witte-Bouma, J., Korteland-van Male, A. M., de Bruijn, A. C., van der Sluis, M., Lu, P., van Goudoever, J. B., Wells, J., Dekker, J., van Seuningen, I. & Renes, I. B., 2012, In : PLoS ONE. 7, 6, e38798.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
    goblet cells
    mucins
    Mucins
    Weaning
    weaning
    2010
    59 Citations (Scopus)

    The role of innate signaling in the homeostasis of tolerance and immunity in the intestine.

    Wells, J., Loonen, L. M. P. & Karczewski, J., 2010, In : International Journal of Medical Microbiology. 300, 1, p. 41-48

    Research output: Contribution to journalArticleAcademicpeer-review

    Toll-Like Receptors
    Intestines
    Immunity
    Homeostasis
    Intestinal Mucosa