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Research Output 2005 2019

2019

Corrigendum: Use of UV Treated Milk Powder to Increase Vaccine Efficacy in the Elderly

Schaefer, S., Hettinga, K. A., Cullor, J., German, J. B. & Henrick, B. M., 18 Mar 2019, In : Frontiers in Immunology. 10, 1 p., 427.

Research output: Contribution to journalComment/Letter to the editorAcademic

Open Access
Powders
Milk
Diphtheria-Tetanus-acellular Pertussis Vaccines
Vaccines
Research
Open Access
immunoglobulin E
Lactoglobulins
beta-lactoglobulin
Lactose
glycation

Effects of raw milk quality on UHT milk instability

Zhang, C., 2019, Wageningen: Wageningen University. 174 p.

Research output: Thesisinternal PhD, WUAcademic

1 Citation (Scopus)

Fraud vulnerability in the Dutch milk supply chain: Assessments of farmers, processors and retailers

Yang, Y., Huisman, W., Hettinga, K. A., Liu, N., Heck, J., Schrijver, G. H., Gaiardoni, L. & van Ruth, S. M., 1 Jan 2019, In : Food Control. 95, p. 308-317

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
fraud
Fraud
supply chain
Milk
farmers

How processing may affect milk protein digestion and overall physiological outcomes: A systematic review

van Lieshout, G. A. A., Lambers, T. T., Bragt, M. C. E. & Hettinga, K. A., 22 Aug 2019, In : Critical Reviews in Food Science and Nutrition.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Milk Proteins
systematic review
dairy protein
Proteolysis
digestion

Human Milk Short-Chain Fatty Acid Composition is Associated with Adiposity Outcomes in Infants

Prentice, P. M., Schoemaker, M. H., Vervoort, J., Hettinga, K., Lambers, T. T., van Tol, E. A. F., Acerini, C. L., Olga, L., Petry, C. J., Hughes, I. A., Koulman, A., Ong, K. K. & Dunger, D. B., May 2019, In : The Journal of Nutrition. 149, 5, p. 716-722

Research output: Contribution to journalArticleAcademicpeer-review

Volatile Fatty Acids
Adiposity
Human Milk
formic acid
Skinfold Thickness
1 Citation (Scopus)
Open Access
Lactoglobulins
glycation
beta-lactoglobulin
hydrophobicity
Hydrophobic and Hydrophilic Interactions

Persistent challenges in safety and hygiene control practices in emerging dairy chains: The case of Tanzania

Ledo, J., Hettinga, K. A., Bijman, J. & Luning, P. A., 1 Nov 2019, In : Food Control. 105, p. 164-173 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Tanzania
Hygiene
hygiene
control methods
dairies

Short communication: Changes under low ambient temperatures in the milk lipodome and metabolome of mid-lactation cows after dehorning as a calf

Baars, T., Jahreis, G., Lorkowski, S., Rohrer, C., Vervoort, J. & Hettinga, K., Mar 2019, In : Journal of Dairy Science. 102, 3, p. 2698-2702

Research output: Contribution to journalArticleAcademicpeer-review

dehorning
metabolome
Metabolome
Lactation
ambient temperature
1 Citation (Scopus)

The Extracellular Protease AprX from Pseudomonas and its Spoilage Potential for UHT Milk: A Review

Zhang, C., Bijl, E., Svensson, B. & Hettinga, K., Jul 2019, In : Comprehensive Reviews in Food Science and Food Safety. 18, 4, p. 834-852

Research output: Contribution to journalReview articleAcademicpeer-review

UHT milk
Pseudomonas
psychrotrophic bacteria
spoilage
Milk

Variability of Serum Proteins in Chinese and Dutch Human Milk during Lactation

Elwakiel, M., Boeren, S., Hageman, J. A., Szeto, I. M., Schols, H. A. & Hettinga, K. A., 27 Feb 2019, In : Nutrients. 11, 3

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Human Milk
breast milk
Lactation
blood proteins
Blood Proteins
2018

Comparing and combining proxies for methane emission of lactating Holstein Friesian cows

van Gastelen, S., Hettinga, K. A. & Dijkstra, J., 2 Sep 2018, p. 588-588.

Research output: Contribution to conferenceAbstractAcademic

Open Access
4 Citations (Scopus)

Destabilization of UHT milk by protease AprX from Pseudomonas fluorescens and plasmin

Zhang, C., Bijl, E. & Hettinga, K., 15 Oct 2018, In : Food Chemistry. 263, p. 127-134 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

UHT milk
Pseudomonas fluorescens
plasmin
Fibrinolysin
Milk
7 Citations (Scopus)

Evaluation of portable near-infrared spectroscopy for organic milk authentication

Liu, N., Parra, H. A., Pustjens, A., Hettinga, K., Mongondry, P. & van Ruth, S. M., 1 Jul 2018, In : Talanta. 184, p. 128-135

Research output: Contribution to journalArticleAcademicpeer-review

Near infrared spectroscopy
Near-Infrared Spectroscopy
Authentication
Milk
Fraud
3 Citations (Scopus)

Human Milk Oligosaccharides in Colostrum and Mature Milk of Chinese Mothers: Lewis Positive Secretor Subgroups

Elwakiel, M., Hageman, J. A., Wang, W., Szeto, I. M., van Goudoever, J. B., Hettinga, K. A. & Schols, H. A., 11 Jul 2018, In : Journal of Agricultural and Food Chemistry. 66, 27, p. 7036-7043

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Colostrum
Human Milk
breast milk
colostrum
Oligosaccharides
1 Citation (Scopus)

Omics and systems biology: Integration of production and omics data in systems biology

Hettinga, K. & Zhang, L., 1 Feb 2018, Proteomics in Domestic Animals: from Farm to Systems Biology. Springer International Publishing, p. 463-485

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Systems Integration
animal physiology
Systems Biology
Information Systems
Animals
7 Citations (Scopus)
Volatile Organic Compounds
Proton transfer
volatile organic compounds
milk composition
protons
4 Citations (Scopus)

Predicting enteric methane emission of dairy cows with milk Fourier-transform infrared spectra and gas chromatography–based milk fatty acid profiles

van Gastelen, S., Mollenhorst, H., Antunes-Fernandes, E. C., Hettinga, K. A., van Burgsteden, G. G., Dijkstra, J. & Rademaker, J. L. W., Jun 2018, In : Journal of Dairy Science. 101, 6, p. 5582-5598

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Methane
Fourier Analysis
Gas Chromatography
Fourier Transform Infrared Spectroscopy
methane

Short communication: The effect of linseed oil and DGAT1 K232A polymorphism on the methane emission prediction potential of milk fatty acids

van Gastelen, S., Antunes-Fernandes, E. C., Hettinga, K. A. & Dijkstra, J., Jun 2018, In : Journal of Dairy Science. 101, 6, p. 5599-5604

Research output: Contribution to journalArticleAcademicpeer-review

Diacylglycerol O-Acyltransferase
Linseed Oil
acyltransferases
linseed oil
Methane
1 Citation (Scopus)

The relationship between milk metabolome and methane emission of Holstein Friesian dairy cows: Metabolic interpretation and prediction potential

van Gastelen, S., Antunes Fernandes, E. C., Hettinga, K. A. & Dijkstra, J., Mar 2018, In : Journal of Dairy Science. 101, 3, p. 2110-2126

Research output: Contribution to journalArticleAcademicpeer-review

metabolome
Metabolome
Methane
methane
Milk

Use of UV treated milk powder to increase vaccine efficacy in the elderly

Schaefer, S., Hettinga, K. A., Cullor, J., German, J. B. & Henrick, B. M., 17 Oct 2018, In : Frontiers in Immunology. 9, OCT, 2254.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Powders
Milk
Vaccines
Immune System
Soybean Proteins
2017
10 Citations (Scopus)

An interactomics overview of the human and bovine milk proteome over lactation

Zhang, L., van Dijk, A-J. & Hettinga, K., 2017, In : Proteome Science. 15, 1.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Human Milk
Proteome
Lactation
Milk
Milk Proteins

Contribution of Dairy to Nutrient Intake in the Western Diet

Hettinga, K. & van Valenberg, H., 30 Jun 2017, Nutrients in Dairy and Their Implications for Health and Disease. Watson, R. R., Collier, R. J. & Preedy, V. R. (eds.). Academic Press, p. 251-258

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Food
Dairy Products
Western Diet
Feeding Behavior
Developing Countries

Dry period length of dairy cows: milk composition and quality

de Vries, R., 2017, Wageningen: Wageningen University. 141 p.

Research output: Thesisinternal PhD, WUAcademic

Open Access
dry period (lactation)
milk quality
milk composition
dairy cows
milk
12 Citations (Scopus)

Effect of processing intensity on immunologically active bovine milk serum proteins

Brick, T., Ege, M., Boeren, S., Böck, A., Von Mutius, E., Vervoort, J. & Hettinga, K., 2017, In : Nutrients. 9, 9, p. 1-14 963.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Milk Proteins
whey
blood proteins
Blood Proteins
Milk

Het behandelen van koemelkallergie... met koemelk

Hettinga, K. A., Wichers, H. J. & De Jong, N. W., 2017, In : VoedingsMagazine. 1, p. 10-12

Research output: Contribution to journalArticleProfessional

Open Access
9 Citations (Scopus)

Human milk peptides differentiate between the preterm and term infant and across varying lactational stages

Dingess, K. A., de Waard, M., Boeren, S., Vervoort, J., Lambers, T. T., van Goudoever, J. B. & Hettinga, K., 1 Oct 2017, In : Food & Function. 8, 10, p. 3769-3782

Research output: Contribution to journalArticleAcademicpeer-review

Human Milk
breast milk
Premature Infants
peptides
Peptides

Invloed van natuurkorst op ontwikkeling van geur tijdens kaasrijping

Hettinga, K. A., 2017, In : De zelfkazer. 69, 2, p. 10-12

Research output: Contribution to journalArticleProfessional

6 Citations (Scopus)
Open Access
Linseed Oil
linseed oil
Rumen
Methane
nitrogen metabolism

Predicting methane emission of dairy cows using milk composition

van Gastelen, S., 2017, Wageningen: Wageningen University. 266 p.

Research output: Thesisinternal PhD, WUAcademic

Open Access
milk composition
methane
dairy cows
milk
Fourier transform infrared spectroscopy
15 Citations (Scopus)

Recent advances in phospholipids from colostrum, milk and dairy by-products

Verardo, V., Gómez-Caravaca, A. M., Arráez-Román, D. & Hettinga, K., 2017, In : International Journal of Molecular Sciences. 18, 1, 173.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Colostrum
milk
Dairy Products
Dairies
Phospholipids
6 Citations (Scopus)

Relationships between methane emission of Holstein Friesian dairy cows and fatty acids, volatile metabolites and non-volatile metabolites in milk

van Gastelen, S., Antunes-Fernandes, E. C., Hettinga, K. A. & Dijkstra, J., 2017, In : Animal. 11, 9, p. 1539-1548

Research output: Contribution to journalArticleAcademicpeer-review

volatile fatty acids
methane
Holstein
dairy cows
metabolites

Using milk Fourier-transform infrared spectra and gas chromatography-based milk fatty acid profiles to predict methane emission of dairy cows

van Gastelen, S., Mollenhorst, H., Antunes Fernandes, E. C., Hettinga, K. A., van Burgsteden, G. G., Dijkstra, J. & Rademaker, J. L. W., 11 Oct 2017.

Research output: Contribution to conferenceOtherAcademic

methane
dairy cows
gas chromatography
fatty acid composition
milk
2016
12 Citations (Scopus)

A proteomics-based identification of putative biomarkers for disease in bovine milk

van Altena, S. E. C., de Klerk, B., Hettinga, K. A., van Neerven, R. J. J., Boeren, S., Savelkoul, H. F. J. & Tijhaar, E. J., 2016, In : Veterinary Immunology and Immunopathology. 174, p. 11-18

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Cattle Diseases
Lactoferrin
Proteomics
proteomics
biomarkers
13 Citations (Scopus)

Changes over lactation in breast milk serum proteins involved in the maturation of immune and digestive system of the infant

Zhang, L., de Waard, M., Verheijen, H., Boeren, S., Hageman, J. A., van Hooijdonk, T., Vervoort, J., van Goudoever, J. B. & Hettinga, K., 2016, In : Journal of Proteomics. 147, p. 40-47

Research output: Contribution to journalArticleAcademicpeer-review

Digestive system
Digestive System
Milk Proteins
Immune system
Human Milk

Extensive dry heating-induced changes in physicochemical and immunological properties of whey proteins

Liu, F., 2016, Wageningen: Wageningen University. 146 p.

Research output: Thesisinternal PhD, WUAcademic

Open Access
Heating
Dendritic Cells
Macrophages
Immune Tolerance
Milk
8 Citations (Scopus)
glycation
Lactose
whey protein
lactose
Digestion

Integrated milk metabolome increases accuracy of methane prediction models and relates energetic pathways to methane production in dairy cows

Antunes Fernandes, E. C., van Gastelen, S., Dijkstra, J., Vervoort, J. & Hettinga, K. A., 14 Feb 2016.

Research output: Contribution to conferencePosterAcademic

8 Citations (Scopus)

Milk metabolome relates enteric methane emission to milk synthesis and energy metabolism pathways

Antunes-Fernandes, E. C., van Gastelen, S., Dijkstra, J., Hettinga, K. A. & Vervoort, J., 2016, In : Journal of Dairy Science. 99, 8, p. 6251-6262

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
milk synthesis
metabolome
Metabolome
Methane
energy metabolism
6 Citations (Scopus)

Proteomics data in support of the quantification of the changes of bovine milk proteins during mammary gland involution

Boggs, I., Hine, B., Smolenksi, G., Hettinga, K., Zhang, L. & Wheeler, T. T., 2016, In : Data in Brief. 8, p. 52-55

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
quantification
16 Citations (Scopus)

Proteomic study on the stability of proteins in bovine, camel, and caprine milk sera after processing

Zhang, L., Boeren, S., Smits, M., van Hooijdonk, T., Vervoort, J. & Hettinga, K., 2016, In : Food Research International. 82, p. 104-111

Research output: Contribution to journalArticleAcademicpeer-review

camel milk
Pasteurization
Camelus
Protein Stability
Milk Proteins
9 Citations (Scopus)

Relationships between milk fatty acid profiles and enteric methane production in dairy cattle fed grass- or grass silage-based diets

Dijkstra, J., van Gastelen, S., Antunes Fernandes, E. C., Warner, D., Hatew, B., Klop, G., Podesta, S. C., van Lingen, H. J., Hettinga, K. A. & Bannink, A., 2016, In : Animal Production Science. 56, 3, p. 541-548

Research output: Contribution to journalArticleAcademicpeer-review

Silage
cattle feeds
Methane
grass silage
Poaceae
4 Citations (Scopus)

Short communication: Influence of shortening the dry period of Swedish dairy cows on plasmin activity in milk

de Vries, R., Brandt, M., Lundh, Å., Holtenius, K., Hettinga, K. & Johansson, M., 2016, In : Journal of Dairy Science. 99, 11, p. 9300-9306

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
dry period (lactation)
plasmin
Fibrinolysin
shortenings
animal communication
16 Citations (Scopus)
Open Access
Maillard Reaction
binding capacity
Maillard reaction
whey protein
Heating
13 Citations (Scopus)

The protein and lipid composition of the membrane of milk fat globules depends on their size

Lu, J., Argov-Argaman, N., Anggrek, J., Boeren, S., van Hooijdonk, T., Vervoort, J. & Hettinga, K. A., 2016, In : Journal of Dairy Science. 99, 6, p. 4726-4738 74498.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
fat globules
protein composition
Membrane Lipids
lipid composition
milk fat

Using milk composition to estimate methane emission of dairy cattle

van Gastelen, S., Antunes Fernandes, E. C., Hettinga, K. A. & Dijkstra, J., 28 Sep 2016, p. 63-65.

Research output: Contribution to conferenceAbstractAcademic

2015
13 Citations (Scopus)

A proteomic perspective on the changes in milk proteins due to high somatic cell count

Zhang, L., Boeren, J. A., van Hooijdonk, A. C. M., Vervoort, J. J. M. & Hettinga, K. A., 2015, In : Journal of Dairy Science. 98, 8, p. 5339-5351

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Milk Proteins
milk proteins
somatic cell count
Proteomics
proteomics
32 Citations (Scopus)

Bovine Milk Proteome in the First 9 Days: Protein Interactions in Maturation of the Immune and Digestive System of the Newborn

Zhang, L., Boeren, J. A., Hageman, J. A., van Hooijdonk, A. C. M., Vervoort, J. J. M. & Hettinga, K. A., 2015, In : PLoS ONE. 10, 2, 19 p., e0116710.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Digestive system
Digestive System
Immune system
Proteome
proteome
4 Citations (Scopus)

Changes in the repertoire of bovine milk proteins during mammary involution.

Boggs, I., Hine, B., Smolenski, G., Hettinga, K. A., Zhang, L. & Wheeler, T., 2015, In : EuPA Open Proteomics. 9, p. 65-75

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Milk Proteins
Milk
Breast
Proteolysis
Dairies
6 Citations (Scopus)

Dairy in a sustainable diet: a question of balance

van Hooijdonk, A. C. M. & Hettinga, K. A., 2015, In : Nutrition Reviews. 73, S1, p. 48-54

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Diet
Food
Dairy Products
Milk
Gases