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Research Output 2000 2019

2019
2 Citations (Scopus)

A MYB Triad Controls Primary and Phenylpropanoid Metabolites for Pollen Coat Patterning

Battat, M., Eitan, A., Rogachev, I., Hanhineva, K., Fernie, A., Tohge, T., Beekwilder, J. & Aharoni, A., 1 May 2019, In : Plant Physiology. 180, 1, p. 87-108 22 p.

Research output: Contribution to journalArticleAcademicpeer-review

Petunia
phenylpropanoids
Pollen
Arabidopsis
pollen
2 Citations (Scopus)

An analysis of characterized plant sesquiterpene synthases

Durairaj, J., Di Girolamo, A., Bouwmeester, H. J., de Ridder, D., Beekwilder, J. & van Dijk, A. D. J., Feb 2019, In : Phytochemistry. 158, p. 157-165

Research output: Contribution to journalArticleAcademicpeer-review

Sesquiterpenes
sesquiterpenoids
terpenoids
Databases
Mutagenesis

Glucosinolate variability between turnip organs during development

Bonnema, G., Lee, J. G., Shuhang, W., Lagarrigue, D., Bucher, J., Wehrens, R., De Vos, R. & Beekwilder, J., 1 Jun 2019, In : PLoS ONE. 14, 6, e0217862.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Glucosinolates
Brassica napus
turnips
glucosinolates
tubers

Tissue specific expression and genomic organization of bitter sesquiterpene lactone biosynthesis in Cichorium intybus L. (Asteraceae)

Bogdanovic, M., Cankar, K., Todorovic, S., Dragicevic, M., Simonovic, A., van Houwelingen, A. M. M. L., Schijlen, E. G. W. M., Schipper, A., Gagneul, D., Hendriks, T., Quillet, M-C., Bouwmeester, H. J., Bosch, H. J. & Beekwilder, M. J., Mar 2019, In : Industrial Crops and Products. 129, p. 253-260

Research output: Contribution to journalArticleAcademicpeer-review

Cichorium intybus
chicory
sesquiterpenoid lactones
Asteraceae
biosynthesis

Toward developing a yeast cell factory for the production of prenylated flavonoids

Levisson, M., Araya-Cloutier, C., De Bruijn, W. J. C., Van Der Heide, M., Salvador López, J. M., Daran, J. M., Vincken, J. P. & Beekwilder, J., 24 Apr 2019, In : Journal of Agricultural and Food Chemistry.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
factories
Flavonoids
Yeast
Industrial plants
flavonoids
2018
5 Citations (Scopus)

Effect of dietary fiber (inulin) addition on phenolics and in vitro bioaccessibility of tomato sauce

Tomas, M., Beekwilder, J., Hall, R. D., Diez Simon, C., Sagdic, O. & Capanoglu, E., 1 Apr 2018, In : Food Research International. 106, p. 129-135

Research output: Contribution to journalArticleAcademicpeer-review

tomato sauce
Inulin
inulin
Dietary Fiber
Lycopersicon esculentum
8 Citations (Scopus)

Engineering de novo anthocyanin production in Saccharomyces cerevisiae

Levisson, M., Patinios, C., Hein, S., de Groot, P. A., Daran, J. M., Hall, R. D., Martens, S. & Beekwilder, J., 3 Jul 2018, In : Microbial Cell Factories. 17, 1, 103.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Anthocyanins
Yeast
Saccharomyces cerevisiae
Glucosides
Yeasts
4 Citations (Scopus)

Engineering storage capacity for volatile sesquiterpenes in Nicotiana benthamiana leaves

Delatte, T. L., Scaiola, G., Molenaar, J., de Sousa Farias, K., Alves Gomes Albertti, L., Busscher, J., Verstappen, F., Carollo, C., Bouwmeester, H. & Beekwilder, J., Dec 2018, In : Plant Biotechnology Journal. 16, 12, p. 1997-2006

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
alpha-bisabolol
Nicotiana benthamiana
Sesquiterpenes
sesquiterpenoids
lipid bodies

From plant to plastic: Metabolic engineering of plant monoterpenes for biobased commodity chemicals

Jongedijk, E., 2018, Wageningen: Wageningen University. 165 p.

Research output: Thesisinternal PhD, WUAcademic

2 Citations (Scopus)

Identification of the Bisabolol Synthase in the Endangered Candeia Tree (Eremanthus erythropappus (DC) McLeisch)

Alves Gomes Albertti, L., Delatte, T. L., de Souza Farias, K., Boaretto, A. G., Verstappen, F. W. A., van Houwelingen, A. M. M. L., Cankar, K., Bouwmeester, H. J. & Beekwilder, M. J., 19 Sep 2018, In : Frontiers in Plant Science. 9, 1340.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Eremanthus
alpha-bisabolol
tissue repair
nursing care
gene expression
1 Citation (Scopus)

In depth investigation of the metabolism of Nectandra megapotamica chemotypes

de S. Farias, K., Delatte, T., do C. de O. Arruda, R., Alves, F. M., Silva, D. B., Beekwilder, J. & Carollo, C. A., 1 Aug 2018, In : PLoS ONE. 13, 8, e0201996.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Nectandra
chemotypes
Metabolites
Metabolism
Volatile Oils

Methyl Perillate as a Highly Functionalized Natural Starting Material for Terephthalic Acid

Jongedijk, E. J., van der Klis, F., de Zwart, R., van Es, D. S. & Beekwilder, M. J., 8 Feb 2018, In : ChemistryOpen. 7, 2, p. 201-203

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Chemical modification
Sugars
Microorganisms
Fermentation
terephthalic acid
1 Citation (Scopus)

Nicotiana benthamianaα-galactosidase A1.1 can functionally complement human α-galactosidase A deficiency associated with Fabry disease

Kytidou, K., Beekwilder, J., Artola, M., van Meel, E., Wilbers, R. H. P., Moolenaar, G. F., Goosen, N., Ferraz, M. J., Katzy, R., Voskamp, P., Florea, B. I., Hokke, C. H., Overkleeft, H. S., Schots, A., Bosch, D., Pannu, N. & Aerts, J. M. F. G., 29 Jun 2018, In : Journal of Biological Chemistry. 293, 26, p. 10042-10058

Research output: Contribution to journalArticleAcademicpeer-review

Galactosidases
alpha-Galactosidase
Fabry Disease
Tobacco
Enzyme Replacement Therapy

Santalene synthase

Beekwilder, M. J., van Houwelingen, A. M. M. L., Bosch, H. J., Lentzen, G. F., Melillo, E. & Wisselink, H. W., 7 Sep 2018, Patent No. WO2018160066, Priority date 2 Mar 2018

Research output: PatentOther research output

Open Access
Nucleic Acids
Antibodies
santalol

The effect of isabelin, a sesquiterpene lactone from Ambrosia artemisiifolia on soil microorganisms and human pathogens

Molinaro, F., Tyc, O., Beekwilder, J., Cankar, K., Bertea, C. M., Negre, M. & Garbeva, P., 1 Feb 2018, In : FEMS Microbiology Letters. 365, 4, fny001.

Research output: Contribution to journalArticleAcademicpeer-review

Ambrosia
Sesquiterpenes
Lactones
Soil
Paenibacillus
6 Citations (Scopus)

Transcription factor mediated control of anthocyanin biosynthesis in vegetative tissues

Outchkourov, N. S., Karlova, R. B., Hölscher, M., Schrama, X., Blilou, I., Jongedijk, E. J., Diez Simon, C., van Dijk, A. D. J., Bosch, H. J., Hall, R. D. & Beekwilder, M. J., Feb 2018, In : Plant Physiology. 176, 2, p. 1862-1878

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Anthocyanins
anthocyanins
Transcription Factors
transcription factors
biosynthesis
2017
16 Citations (Scopus)

Fungal volatile compounds induce production of the secondary metabolite Sodorifen in Serratia plymuthica PRI-2C

Schmidt, R., de Jager, V., Zühlke, D., Wolff, C., Bernhardt, J., Cankar, K., Beekwilder, J., van IJcken, W., Sleutels, F., de Boer, W., Riedel, K. & Garbeva, P., 2017, In : Scientific Reports. 7, 862.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
secondary metabolite
volatile organic compound
bacterium
terpene
fungus
9 Citations (Scopus)

Identification of major loci and genomic regions controlling acid and volatile content in tomato fruit: Implications for flavor improvement

Bauchet, G., Grenier, S., Samson, N., Segura, V., Kende, A., Beekwilder, J., Cankar, K., Gallois, J. L., Gricourt, J., Bonnet, J., Baxter, C., Grivet, L. & Causse, M., 2017, In : New Phytologist. 215, 2, p. 624-641

Research output: Contribution to journalArticleAcademicpeer-review

Lycopersicon esculentum
Fruit
flavor
tomatoes
metabolites
15 Citations (Scopus)

Industrial processing versus home processing of tomato sauce: Effects on phenolics, flavonoids and in vitro bioaccessibility of antioxidants

Tomas, M., Beekwilder, J., Hall, R. D., Sagdic, O., Boyacioglu, D. & Capanoglu, E., 2017, In : Food Chemistry. 220, p. 51-58

Research output: Contribution to journalArticleAcademicpeer-review

tomato sauce
sauces
Lycopersicon esculentum
Fruits
processing technology
9 Citations (Scopus)

Processing black mulberry into jam: Effects on antioxidant potential and in vitro bioaccessibility

Tomas, M., Toydemir, G., Boyacioglu, D., Hall, R. D., Beekwilder, M. J. & Capanoglu, E., 2017, In : Journal of the Science of Food and Agriculture. 97, 10, p. 3106-3113

Research output: Contribution to journalArticleAcademicpeer-review

Morus nigra
Morus
jams
Antioxidants
antioxidants

Prunus fruit juices

Toydemir, G., Boyacioglu, D., Hall, R. D., Beekwilder, M. J. & Capanoglu, E., 26 May 2017, Innovative Technologies in Beverage Processing. Aguiló-Aguayo, I. & Plaza, L. (eds.). Chichester UK: Wiley, p. 59-77

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Prunus
fruit juices
Prunus cerasus
Prunus avium
pasteurization
2016
38 Citations (Scopus)

A Review on the Effect of Drying on Antioxidant Potential of Fruits and Vegetables

Kamiloglu, S., Toydemir, G., Boyacioglu, D., Beekwilder, J., Hall, R. D. & Capanoglu, E., 2016, In : Critical Reviews in Food Science and Nutrition. 56, p. S110-S129

Research output: Contribution to journalArticleAcademicpeer-review

Vegetables
Fruits
Antioxidants
Fruit
Drying
5 Citations (Scopus)

A single arabidopsis gene encodes two differentially targeted geranylgeranyl diphosphate synthase isoforms

Águila Ruiz-Sola, M., Barja, M. V., Manzano, D., Llorente, B., Schipper, B., Beekwilder, J. & Rodriguez-Concepcion, M., 2016, In : Plant Physiology. 172, 3, p. 1393-1402

Research output: Contribution to journalArticleAcademicpeer-review

Farnesyltranstransferase
isoprenoids
Arabidopsis
Plastids
plastids
32 Citations (Scopus)

Biotechnological production of limonene in microorganisms

Jongedijk, E., Cankar, K., Buchhaupt, M., Schrader, J., Bouwmeester, H. & Beekwilder, J., 2016, In : Applied Microbiology and Biotechnology. 100, 7, p. 2927-2938

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Biocompatible Materials
Monoterpenes
limonene
Citrus
Biotechnology

Cherry Juice

Toydemir, G., Boyacioglu, D., Beekwilder, M. J., Hall, R. D. & Capanoglu, E., 2016, Handbook of Functional Beverages and Human Health. CRC Press, p. 175-185

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

6 Citations (Scopus)

Fruit antioxidants during vinegar processing: Changes in content and in vitro bio-accessibility

Bakir, S., Toydemir, G., Boyacioglu, D., Beekwilder, J. & Capanoglu, E., 2016, In : International Journal of Molecular Sciences. 17, 10, 12 p., 1658.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
fruits
antioxidants
Fruits
Antioxidants
Acetic Acid
8 Citations (Scopus)

Genome-wide identification of bahd acyltransferases and in vivo characterization of HQT-like enzymes involved in caffeoylquinic acid synthesis in globe artichoke

Moglia, A., Acquadro, A., Eljounaidi, K., Milani, A. M., Cagliero, C., Rubiolo, P., Genre, A., Cankar, K., Beekwilder, J. & Comino, C., 2016, In : Frontiers in Plant Science. 7, September, 1424.

Research output: Contribution to journalArticleAcademicpeer-review

hydroxycinnamoyltransferase
acyltransferases
artichokes
chlorogenic acid
synthesis
2015
17 Citations (Scopus)

(+)-Valencene production in Nicotiana benthamiana is increased by down-regulation of competing pathways

Cankar, K., Jongedijk, E. J., Klompmaker, M., Majdic, T., Mumm, R., Bouwmeester, H. J., Bosch, H. J. & Beekwilder, M. J., 2015, In : Biotechnology Journal. 10, 1, p. 180-189

Research output: Contribution to journalArticleAcademicpeer-review

Farnesyl-Diphosphate Farnesyltransferase
Tobacco
Down-Regulation
Farnesol
Metabolic Engineering
14 Citations (Scopus)

Accumulation of cynaropicrin in globe artichoke and localization ofenzymes involved in its biosynthesis

Eljounaidi, K., Comino, C., Moglia, A., Cankar, K., Genre, A., Hehn, A., Bourgaud, F., Beekwilder, J. & Lanteri, S., 2015, In : Plant Science. 239, p. 128-136

Research output: Contribution to journalArticleAcademicpeer-review

Cynara scolymus
artichokes
sesquiterpenoid lactones
Sesquiterpenes
Lactones
28 Citations (Scopus)

Capturing of the monoterpene olefin limonene produced in Saccharomyces cerevisiae

Jongedijk, E. J., Cankar, K., Ranzijn, J., van der Krol, A. R., Bouwmeester, H. J. & Beekwilder, M. J., 2015, In : Yeast. 32, 1, p. 159-171

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Monoterpenes
Alkenes
Yeast
Olefins
Saccharomyces cerevisiae
16 Citations (Scopus)

Evaluation of the bioactive properties of avenanthramide analogs produced in recombinant yeast

Moglia, A., Goitre, L., Gianoglio, S. & Beekwilder, J., 2015, In : BioFactors. 41, 1, p. 15-27

Research output: Contribution to journalArticleAcademicpeer-review

Yeast
Yeasts
3-Hydroxyanthranilic Acid
Antioxidants
Saccharomyces cerevisiae
21 Citations (Scopus)

Exploring the genomic traits of fungus-feeding bacterial genus Collimonas

Song, C., Schmidt, R., de Jager, V., Krzyzanowska, D., Jongedijk, E., Cankar, K., Beekwilder, J., van Veen, A., de Boer, W., van Veen, J. A. & Garbeva, P., 24 Dec 2015, In : BMC Genomics. 16, 1, 1103.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Fungi
Genome
Peptide Synthases
Genes
Lipopeptides
26 Citations (Scopus)

The effects of juice processing on black mulberry antioxidants

Tomas, M., Toydemir, G., Boyacioglu, D., Hall, R. D., Beekwilder, M. J. & Capanoglu, E., 2015, In : Food Chemistry. 186, p. 277-284

Research output: Contribution to journalArticleAcademicpeer-review

Morus nigra
Morus
Fruits
juices
Fruit
2014
7 Citations (Scopus)

An O-methyltransferase modifies accumulation of methylated anthocyanins in seedlings of tomato

Gomez Roldan, M. V., Outchkourov, N. S., van Houwelingen, A. M. M. L., Lammers, M., Romero Fuente, I., Ziklo, N., Aharoni, A., Hall, R. D. & Beekwilder, M. J., 2014, In : The Plant Journal. 80, 4, p. 695-708

Research output: Contribution to journalArticleAcademicpeer-review

Anthocyanins
methyltransferases
Methyltransferases
Lycopersicon esculentum
Seedlings
17 Citations (Scopus)

Control of anthocyanin and non-flavonoid compounds by anthocyanin-regulating MYB and bHLH transcription factors in Nicotiana benthamiana leaves

Outchkourov, N. S., Carollo, C. A., Gomez Roldan, M. V., de Vos, C. H., Bosch, H. J., Hall, R. D. & Beekwilder, M. J., 2014, In : Frontiers in Plant Science. 5, 9 p., 519.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
delphinidin
Nicotiana benthamiana
rutin
anthocyanins
transcription factors
24 Citations (Scopus)

Cytochrome P450s from Cynara cardunculus L. CYP71AV9 andCYP71BL5, catalyze distinct hydroxylations in the sesquiterpenelactone biosynthetic pathway

Eljounaidi, K., Cankar, K., Comino, C., Moglia, A., Hehn, A., Bourgaud, F., Bouwmeester, H. J., Menin, B., Lanteri, S. & Beekwilder, M. J., 2014, In : Plant Science. 223, p. 59-68

Research output: Contribution to journalArticleAcademicpeer-review

Cynara
Cynara cardunculus
germacrene
Biosynthetic Pathways
hydroxylation
18 Citations (Scopus)
Catechin
Methane
Ruminants
Greenhouse gases
Hydrogen
12 Citations (Scopus)

IdsA is the major geranylgeranyl pyrophosphate synthase involved in carotenogenesis in Corynebacterium glutamicum

Heider, S. A. E., Peters-Wendisch, P., Beekwilder, M. J. & Wendisch, V. F., 2014, In : FEBS Journal. 281, 21, p. 4906-4920

Research output: Contribution to journalArticleAcademicpeer-review

Geranylgeranyl-Diphosphate Geranylgeranyltransferase
Corynebacterium glutamicum
Carotenoids
Dimethylallyltranstransferase
Genes
2 Citations (Scopus)

Metabolic diversity in apple germplasm

Khan, S. A., Tikunov, Y. M., Chibon, P. Y. F. R. P., Maliepaard, C. A., Beekwilder, M. J., Jacobsen, E. & Schouten, H. J., 2014, In : Plant Breeding. 133, 2, p. 281-290

Research output: Contribution to journalArticleAcademicpeer-review

Catechin
Malus
phenolic compounds
germplasm
Enoyl-CoA Hydratase
40 Citations (Scopus)

Metabolomic engineering for the microbial production of cartenoids and related products with a focus on the rare C50 carotenoids

Heider, S. A. E., Peters-Wendisch, P., Wendisch, V. F. & Beekwilder, M. J., 2014, In : Applied Microbiology and Biotechnology. 98, 10, p. 4355-4368

Research output: Contribution to journalReview articleAcademicpeer-review

Metabolomics
Carotenoids
Metabolic Engineering
Biological Phenomena
Singlet Oxygen
24 Citations (Scopus)

Orientation of llama antibodies strongly increases sensitivity of biosensors

Trilling, A. K., Hesselink, T., van Houwelingen, A., Cordewener, J. H. G., Jongsma, M. A., Schoffelen, S., van Hest, J. C. M., Zuilhof, J. T. & Beekwilder, J., 2014, In : Biosensors and Bioelectronics. 60, p. 130-136

Research output: Contribution to journalArticleAcademicpeer-review

New World Camelids
Azides
Biosensing Techniques
Biosensors
Antibodies
45 Citations (Scopus)

Polycistronic expression of a ß-carotene biosynthetic pathway in Saccharomyces cerevisiae coupled to ß-ionone production

Beekwilder, J., Rossum, H. M., Koopman, F., Sonntag, F., Buchhaupt, M., Schrader, J., Hall, R. D., Bosch, H. J., Pronk, J. T., van Maris, A. J. A. & Daran, J. M., 2014, In : Journal of Biotechnology. 192, partB, p. 383-392

Research output: Contribution to journalArticleAcademicpeer-review

Norisoprenoids
Biosynthetic Pathways
Carotenoids
Yeast
Saccharomyces cerevisiae
8 Citations (Scopus)

Production of (+)-valencene in the mushroom-forming fungus S. commune

Scholtmeijer, K., Beekwilder, J., Cankar, K., Wösten, H. A. B., Lugones, L. G. & Bosch, H. J., 2014, In : Applied Microbiology and Biotechnology. 98, 11, p. 5059-5068

Research output: Contribution to journalArticleAcademicpeer-review

Agaricales
Sesquiterpenes
Fungi
Schizophyllum
Culture Media

Sour Cherry (Prunus cerasus L.) Anthocyanins: effects of juice processing on phenolic compounds and bioavailability

Toydemir, G., Boyacioglu, D., Beekwilder, M. J., de Vos, R. C. H., Hall, R. D. & Capanoglu, E., 2014, 10th International Vaccinium & Other Superfruits Symposium and Exhibition. Vol. 1017. p. 387-398

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Prunus cerasus
bioavailability
anthocyanins
juices
phenolic compounds
18 Citations (Scopus)

Valencene oxidase CYP706M1 from Alaska cedar (Callitropsis nootkatensis)

Cankar, K., van Houwelingen, A. M. M. L., Goedbloed, M. A., Renirie, R., de Jong, R. M., Bouwmeester, H. J., Bosch, H. J., Sonke, T. & Beekwilder, M. J., 2014, In : FEBS Letters. 588, 6, p. 1001-1007

Research output: Contribution to journalArticleAcademicpeer-review

Cytochrome P-450 Enzyme System
Citrus paradisi
Oxidoreductases
Yeast
Yeasts
40 Citations (Scopus)

Valencene synthase from the heartwood of Nootka cypress (Callitropsis nootkatensis) for biotechnological production of valencene

Beekwilder, M. J., van Houwelingen, A. M. M. L., Cankar, K., van Dijk, A. D. J., de Jong, R., Stoopen, G. M., Bouwmeester, H. J., Achkar, J., Sonke, T. & Bosch, H. J., 2014, In : Plant Biotechnology Journal. 12, 2, p. 174-182

Research output: Contribution to journalArticleAcademicpeer-review

nootkatone
Cupressus
Xanthocyparis nootkatensis
heartwood
terpenoids
2013
5 Citations (Scopus)

16 kDa Heat Shock Protein from Heat-Inactivated Mycobacterium tuberculosis Is a Homodimer – Suitability for Diagnostic Applications with Specific Llama VHH Monoclonals

Srivastava, S. K., Ruigrok, V. J. B., Thompson, N. J., Trilling, A. K., Heck, A. J. R., van Rijn, C. J. M., Beekwilder, M. J. & Jongsma, M. A., 2013, In : PLoS ONE. 8, 5, e64040.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
New World Camelids
llamas
Mycobacterium tuberculosis
Heat-Shock Proteins
heat shock proteins
173 Citations (Scopus)

Antibody orientation on biosensor surfaces: a minireview

Trilling, A. K., Beekwilder, M. J. & Zuilhof, H., 2013, In : The Analyst. 138, 6, p. 1619-1627

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Biosensing Techniques
Biosensors
Antibodies
Immobilization
antibody
186 Citations (Scopus)

Biosynthesis of Antinutritional Alkaloids in Solanaceous Crops Is Mediated by Clustered Genes

Itkin, M., Heinig, U., Tzfadia, O., Bhide, A. J., Shinde, B., Cardenas, P. D., Bocobza, S. E., Unger, T., Malitsky, S., Finkers, H. J., Tikunov, Y. M., Bovy, A. G., Chikate, Y., Singh, P., Rogachev, I., Beekwilder, J., Giri, A. P. & Aharoni, A., 2013, In : Science. 341, 6142, p. 175-179

Research output: Contribution to journalArticleAcademicpeer-review

glycoalkaloids
alkaloids
biosynthesis
crops
tomatoes