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Fingerprint Dive into the research topics where Jorick Bruins is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 14 Similar Researchers
Cycloaddition Engineering & Materials Science
Proteins Engineering & Materials Science
Quinones Chemical Compounds
Antibodies Engineering & Materials Science
Tyrosine Medicine & Life Sciences
Labeling Chemical Compounds
Cycloaddition Reaction Medicine & Life Sciences
Click Chemistry Medicine & Life Sciences

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Research Output 2017 2019

Highly efficient mono-functionalization of knob-in-hole antibodies with strain-promoted click chemistry

Bruins, J. J., van de Wouw, C., Koen, W., Lina, B., Albada, B. & van Delft, F. L., 8 Jul 2019, In : Journal of the American Chemical Society. 4, p. 11801-11807 4.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Click Chemistry
Knobs
Monoclonal antibodies
Antibodies
Dimers
1 Citation (Scopus)

Inducible, selective labeling of proteins via enzymatic oxidation of tyrosine

Bruins, J. J., van de Wouw, C., Keijzer, J. F., Albada, B. & van Delft, F. L., 4 Jun 2019, Methods in Molecular Biology. Hertfordshire: Springer, p. 357-368 12 p. (Methods in Molecular Biology; vol. 2012).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Tyrosine
Cycloaddition Reaction
Proteins
Alkynes
Monophenol Monooxygenase
8 Citations (Scopus)

Orthogonal, dual protein labelling by tandem cycloaddition of strained alkenes and alkynes to: Ortho -quinones and azides

Bruins, J. J., Blanco-Ania, D., van der Doef, V., van Delft, F. L. & Albada, B., 1 Jan 2018, In : Chemical Communications. 54, 53, p. 7338-7341

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Quinones
Alkynes
Azides
Cycloaddition
Alkenes
18 Citations (Scopus)

Ortho-Quinones and Analogues Thereof: Highly Reactive Intermediates for Fast and Selective Biofunctionalization

Bruins, J. J., Albada, B. & van Delft, F., 3 Apr 2018, In : Chemistry - A European Journal. 24, 19, p. 4749-4756

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Quinones
Cycloaddition
Oxidants
Enzymes
Proteins
18 Citations (Scopus)

Inducible, Site-Specific Protein Labeling by Tyrosine Oxidation-Strain-Promoted (4 + 2) Cycloaddition

Bruins, J. J., Westphal, A. H., Albada, B., Wagner, K., Bartels, L., Spits, H., van Berkel, W. J. H. & van Delft, F. L., 2017, In : Bioconjugate Chemistry. 28, 4, p. 1189-1193

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Cycloaddition
Fluorophores
Cycloaddition Reaction
Anchors
Antibodies

Projects 2015 2015