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Research Output 1996 2020

2003
21 Citations (Scopus)

Identification and molecular characterization of a novel type of alpha-galactosidase from Pyrococcus furiosus

van Lieshout, J. F. T., Verhees, C. H., Ettema, T. J. G., van der Sar, S., Imamura, H., Matsuzawa, H., van der Oost, J. & de Vos, W. M., 2003, In : Biocatalysis and Biotransformation. 21, 4-5, p. 243-252

Research output: Contribution to journalArticleAcademicpeer-review

Pyrococcus furiosus
Galactosidases
alpha-Galactosidase
formic acid
Amino acids
43 Citations (Scopus)

Molecular and biochemical characterisation of the thermoactive family 1 pectase lyase from the hyperthermophilic bacterium Thermotoga maritima

Kluskens, L. D., van Alebeek, G. J. W. M., Voragen, A. G. J., de Vos, W. M. & van der Oost, J., 2003, In : Biochemical Journal. 370, p. 651-659

Research output: Contribution to journalArticleAcademicpeer-review

Thermotoga maritima
Lyases
pectate disaccharide-lyase
Bacteria
Pectins
40 Citations (Scopus)

Molecular characterization of H2O2-forming NADH oxidases from Archeaoglobus fulgidus

Kengen, S. W. M., van der Oost, J. & de Vos, W. M., 2003, In : European Journal of Biochemistry. 270, 13, p. 2885-2894

Research output: Contribution to journalArticleAcademicpeer-review

Noxae
Genes
Enzymes
Archaeoglobus fulgidus
NADH oxidase
24 Citations (Scopus)

Production by Clostridium acetobutylicum ATCC 824 of CelG, a cellulosomal glycoside hydrolase belonging to family 9

Lopez Contreras, A. M., Martens, A. A., Szijarto, N., Mooibroek, A., Claassen, P. A. M., van der Oost, J. & de Vos, W. M., 2003, In : Applied and Environmental Microbiology. 69, 2, p. 869-877

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Clostridium acetobutylicum
Glycoside Hydrolases
hydrolases
Clostridium cellulovorans
glycosides
7 Citations (Scopus)

Purification, crystallization and preliminary crytallographic analysis of phosphoglucose isomerase from the hyperthermophilic archaeon Pyrococcus furiosus

Akerboom, A. P., Turnbull, A. P., Hargreaves, D., Fischer, M., de Geus, D., Sedelnikova, S. E., Berrisford, J. M., Baker, P. J., Verhees, C. H., van der Oost, J. & Rice, D. W., 2003, In : Acta Crystallographica Section D-Biological Crystallography. 59, p. 1822-1823

Research output: Contribution to journalArticleAcademicpeer-review

Pyrococcus furiosus
Glucose-6-Phosphate Isomerase
Archaea
Crystallization
Selenomethionine
42 Citations (Scopus)

The activity of hyperthermophilic glycosynthases is significantly enhanced at acidic pH

Perugino, G., Trincone, A., Giordano, A., van der Oost, J., Kaper, T., Rossi, M. & Moracci, M., 2003, In : Biochemistry. 42, p. 8484-8493

Research output: Contribution to journalArticleAcademicpeer-review

formic acid
Nucleophiles
Glycoside Hydrolases
Desulfurococcaceae
Glycosides
190 Citations (Scopus)

The Lrp family of transcriptional regulators

Brinkman, A. B., Ettema, T. J. G., de Vos, W. M. & van der Oost, J., 2003, In : Molecular Microbiology. 48, 2, p. 287-294

Research output: Contribution to journalArticleAcademicpeer-review

Binding Sites
Leucine-Responsive Regulatory Protein
DNA
Pyrococcus furiosus
Genome
56 Citations (Scopus)

TRASH, a novel metal binding domain predicted to be involved in heavy metal sensing, trafficking and resistance

Ettema, T. J. G., Huynen, M., de Vos, W. M. & van der Oost, J., 2003, In : Trends in Biochemical Sciences. 28, 4, p. 170-173

Research output: Contribution to journalArticleAcademicpeer-review

Heavy Metals
Genes
Metals
Genome
Hydrogenase
170 Citations (Scopus)

Unique features of glycolysis in Archaea

Verhees, C. H., Kengen, S. W. M., Tuininga, J. E., Schut, G. J., Adams, M. W. W., de Vos, W. M. & van der Oost, J., 2003, In : Biochemical Journal. 375, p. 231-246

Research output: Contribution to journalArticleAcademicpeer-review

Archaea
Glycolysis
Enzymes
Bacteria
Genomics
2002
60 Citations (Scopus)

A novel ligand-binding domain involved in allosteric regulation of amino acid metabolism in prokaryotes

Ettema, T. J. G., Brinkman, A. B., Tani, T. H., Rafferty, J. B. & van der Oost, J., 2002, In : Journal of Biological Chemistry. 277, 40, p. 37464-37468

Research output: Contribution to journalArticleAcademicpeer-review

Allosteric Regulation
Random access storage
Metabolism
Ligands
Amino Acids
39 Citations (Scopus)

Biochemical adaptations of two sugar kinases from the hyperthermophilic archaeon Pyrococcus furiosus

Verhees, C. H., Koot, D. G., Ettema, T. J., Dijkema, C., de Vos, W. M. & van der Oost, J., 2002, In : Biochemical Journal. 366, p. 121-127

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Pyrococcus furiosus
Galactokinase
Archaea
Sugars
Phosphotransferases
30 Citations (Scopus)

Characterization of plasmid pRT1 from Pyrococcus sp. strain JT1

Ward, D. E., Revet, I. M., Nandakumar, R., Tuttle, J. H., de Vos, W. M., van der Oost, J. & DiRuggiero, J., 2002, In : Journal of Bacteriology. 184, p. 2561-2566

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
31 Citations (Scopus)

DNA family shuffling of hyperthermostable beta-glycosidases

Kaper, T., Brouns, S. J. J., Geerling, A. C. M., de Vos, W. M. & van der Oost, J., 2002, In : Biochemical Journal. p. 461-470

Research output: Contribution to journalArticleAcademicpeer-review

DNA Shuffling
Glycoside Hydrolases
Lactose
DNA
Enzymes

Engineering of Thermostable Family 1 B-glycosidases for Saccharide Processing

Kaper, T., van der Oost, J. & de Vos, W. M., 2002, Carbohydrate bioengineering Interdisciplinary Aproaches. Teeri, T. T., Svensson, B., Gilbert, H. J. & Feizi, T. (eds.). Cambridge: Royal Society of Chemistry, p. 135-142

Research output: Chapter in Book/Report/Conference proceedingChapter

17 Citations (Scopus)
Open Access
Pyrococcus furiosus
Aromatic Amino Acids
molecular analysis
amino acid metabolism
transaminases

Molecular and biochemical characterisation of the thermo-active family 1 pectate lyase from the hyperthermophilic bacterium Thermotoga maritima

Kluskens, L. D., van Alebeek, G. J. W. M., Voragen, A. G. J., de Vos, W. M. & van der Oost, J., 2002, In : Biochemical Journal. 20, 34 p.

Research output: Contribution to journalArticleAcademicpeer-review

30 Citations (Scopus)

Molecular and Biochemical Characterization of a Distinct Type of Fructose-1,6- Bisphosphatase from Pyrococcus furiosus

Verhees, C. H., Akkerboom, J., Schiltz, J., de Vos, W. M. & van der Oost, J., 2002, In : Journal of Bacteriology. 184, p. 3401-3405

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Pyrococcus furiosus
Fructose-Bisphosphatase
Conserved Sequence
Enzymes
Substrate Specificity
37 Citations (Scopus)

Molecular characterization of fervidolysin, a subtilisin-like serine protease from the thermophilic bacterium Fervidobacterium pennivorans

Kluskens, L. D., Voorhorst, W. G., Siezen, R. J., Schwerdfeger, R. M., Antranikian, G., van der Oost, J. & de Vos, W. M., 2002, In : Extremophiles. 6, p. 185-194

Research output: Contribution to journalArticleAcademicpeer-review

Subtilisin
Serine Proteases
Keratins
Bacteria
Proteins
35 Citations (Scopus)

Molecular characterization of phosphoglycerate mutase in archaea

van der Oost, J., Huynen, M. A. & Verhees, C. H., 2002, In : FEMS Microbiology Letters. 212, p. 111-120

Research output: Contribution to journalArticleAcademicpeer-review

Phosphoglycerate Mutase
Archaea
Bacteria
Archaeal Genome
Methanocaldococcus
14 Citations (Scopus)

Persistence of tertiary structure in 7.9M guanidinium chloride : the case of endo B-1,3-glucanase from Pyrococcus furiosus

Chiaraluce, R., van der Oost, J., Lebbink, J. H. G., Kaper, T. & Consalvi, V., 2002, In : Biochemistry. 41, p. 14624-14632

Research output: Contribution to journalArticleAcademicpeer-review

Pyrococcus furiosus
Guanidine
Protein folding
Cellulases
Denaturation

Seks in de reageerbuis

van der Oost, J., 2002, In : Natuur en Techniek. p. 11

Research output: Contribution to journalArticlePopular

Snelle selectie in de reageerbuis

van der Oost, J., 2002, In : Natuur en Techniek. p. 66-68

Research output: Contribution to journalArticlePopular

36 Citations (Scopus)

Substrate specificity engineering of beta-mannosidase and betaglucosidase from Pyrococcus by exchange of unique active site residues

Kaper, T., van Heusden, H. H., van Loo, B., Vasella, A., van der Oost, J. & de Vos, W. M., 2002, In : Biochemistry. 41, p. 4147-4155

Research output: Contribution to journalArticleAcademicpeer-review

Pyrococcus
beta-Mannosidase
Substrate Specificity
Hydrolysis
Catalytic Domain
87 Citations (Scopus)

The Sulfolobus solfataricus Lrp-like protein LysM regulates lysine biosynthesis in response to lysine availability

Brinkman, A. B., Bell, S. D., Lebbink, R. J., de Vos, W. M. & van der Oost, J., 2002, In : Journal of Biological Chemistry. 277, p. 29537-29549

Research output: Contribution to journalArticleAcademicpeer-review

Leucine-Responsive Regulatory Protein
Sulfolobus solfataricus
Biosynthesis
Lysine
Availability
2001
11 Citations (Scopus)

ADP-dependent glucokinase and phosphofructo-kinase from Pyrococcus furiosus

Kengen, S. W. M., Tuininga, J. E., Verhees, C. H., van der Oost, J., Stams, A. J. M. & de Vos, W. M., 2001, In : Methods in Enzymology. 331, p. 41-53

Research output: Contribution to journalArticleAcademicpeer-review

41 Citations (Scopus)

ADP-dependent Phosphofructokinases in Mesophilic and Thermophilic Methanogenic Archaea

Verhees, C. H., Tuininga, J. E., Kengen, S. W. M., Stams, A. J. M., van der Oost, J. & de Vos, W. M., 2001, In : Journal of Bacteriology. 183, p. 7145-7153

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Archaea
Thermococcales
Methanocaldococcus
Phosphofructokinases
Eukaryota
86 Citations (Scopus)

Archaeal fructose-1,6-bisphosphate aldolases constitute a new family of archaeal type Class I aldolase

Siebers, B., Tjaden, B., Brinkmann, H., Dorr, C., Lilie, H., van der Oost, J. & Verhees, C. H., 2001, In : Journal of Biological Chemistry. 276, p. 28710-28718

Research output: Contribution to journalArticleAcademicpeer-review

Fructose-Bisphosphate Aldolase
Genes
Pyrococcus furiosus
Archaeal Genome
Microbiology
26 Citations (Scopus)
Archaeoglobus fulgidus
Archaea
Catalase
Peroxidase
Organism Cloning

Clostridium beijerinckii cells expressing Neocallimastix patriciarum glycoside hydrolases show enhanced Lichenan utilization and solvent production

Lopez-Contreras, A., van der Oost, J., Claassen, P., Mooibroek, H. & de Vos, W. M., 2001, In : Applied and Environmental Microbiology. 67, 11, p. 5127-5133

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Clostridium beijerinckii
Neocallimastix
Glycoside Hydrolases
hydrolases
glycosides
2 Citations (Scopus)

Crystallization and quaternary structure analysis of an Lrp-like regulatory protein from the hyperthermophile Pyrococcus furiosus

Sedelnikova, S. E., Smits, S. H. J., Leonard, P. M., Brinkman, A. B., van der Oost, J. & Rafferty, J. B., 2001, In : Acta Crystallographica Section D-Biological Crystallography. 57, 6, p. 886-888

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Leucine-Responsive Regulatory Protein
Pyrococcus furiosus
Crystallization
Proteins
Ammonium Sulfate
1490 Citations (Scopus)

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

Brejc, K., van Dijk, W. J., Klaassen, R. V., Schuurmans, M., van der Oost, J., Smit, A. B. & Sixma, T. K., 2001, In : Nature. 411, p. 269-276

Research output: Contribution to journalArticleAcademicpeer-review

Nicotinic Receptors
Acetylcholine
Carrier Proteins
Ligands
Protein Subunits
115 Citations (Scopus)

Crystal structure of the Lrp-like transcriptional regulator from the archaeon Pyrococcus furiosus

Leonard, P. M., Smits, S. H. J., Svetlana, E., Sedelnikova, S. E., Brinkman, A. B., de Vos, W. M., van der Oost, J., Rice, D. W. & Rafferty, J. B., 2001, In : The EMBO Journal. 20, p. 990-997

Research output: Contribution to journalArticleAcademicpeer-review

21 Citations (Scopus)

Cytochromes c550, c552, c1 in the electron transport network of Paracoccus denitrificans: redundant or subtly different in function?

Otten, M. F., van der Oost, J., Reijnders, W. N. M., Westerhoff, H. V., Ludwig, B. & van Spanning, R. J. M., 2001, In : Journal of Bacteriology. 183, p. 7017-7026

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Paracoccus denitrificans
Electron Transport
Electrons
Electron Transport Complex III
Cytochromes c
9 Citations (Scopus)
Open Access
Desulfitobacterium dehalogenans
Desulfitobacterium
succinate dehydrogenase (quinone)
Succinate Dehydrogenase
Gene Silencing
42 Citations (Scopus)

Genetic and biochemical characterization of a short-chain alcohol dehydrogenase from the hyperthermophilic archaeon Pyrococcus furiosus

van der Oost, J., Voorhorst, W. G. B., Kengen, S. W. M., Geerling, A. C. M., Wittenhorst, V., Gueguen, Y. & de Vos, W. M., 2001, In : European Journal of Biochemistry. 268, p. 3062-3068

Research output: Contribution to journalArticleAcademicpeer-review

Pyrococcus furiosus
Alcohol Dehydrogenase
Archaea
Molecular Biology
Genes

Genetics and molecular biology of anaerobic reductive dehalogenation

Smidt, H., van der Oost, J. & de Vos, W. M., 2001, Anaerobic dehalogenation : Biologische Abwasserreinigung, Berlin 2001. Berlin, p. 15-30

Research output: Chapter in Book/Report/Conference proceedingChapterProfessional

Genetics and molecular biology of anaerobic reductive dehalogenation. In: Schriftenreihe Biologische Abwasserreinigung

Smidt, H., van der Oost, J. & de Vos, W. M., 2001, Schriftenreihe Biologische Abwasserreinigung / Technical University Berlin. Berlin, p. 193

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

65 Citations (Scopus)

Improved oligosaccharide synthesis by protein engineering of b-glucosidase from hyperthermophilic Pyrococcus furiosus

Hanson, T., Kaper, T., van der Oost, J. & de Vos, W. M., 2001, In : Biotechnology and Bioengineering. 73, p. 203-210

Research output: Contribution to journalArticleAcademicpeer-review

Pyrococcus furiosus
Glucosidases
Protein Engineering
Oligosaccharides
Lactose
37 Citations (Scopus)

Modularity in the gain and loss of genes: applications for function prediction

Ettema, T. J. G., van der Oost, J. & Huynen, M., 2001, In : Trends in Genetics. 17, 9, p. 485-487

Research output: Contribution to journalArticleAcademicpeer-review

Genome
Genes
Proteins

Molecular characterization of key enzymes in halorespiration.

Smidt, H., Akkermans, A. D. L., van der Oost, J. & de Vos, W. M., 2001, Biotechnology for the environment, focus on biotechnology. Agathos, S. N. & Reineke, W. (eds.). Dordrecht: Kluwer Academic Publishers, p. 200

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

16 Citations (Scopus)

Properties of the recombinant a-glucosidase from Sulfolobus solfataricus in relation to starch processing

Martino, A., Schiraldi, C., Fusco, S., Di Lernia, I., Costabile, T., Pellicano, T., Marotta, M., Generoso, M., van der Oost, J. & Sensen, C. W., 2001, In : Journal of Molecular Catalysis. B, Enzymatic. 11, p. 787-794

Research output: Contribution to journalArticleAcademicpeer-review

Sulfolobus solfataricus
Glucosidases
Starch
Purification
Enzymes
15 Citations (Scopus)

Purification, characterization, and molecular modelling of pyrolysins and other thermostable serine proteases from hyperthermophilic microorganisms

de Vos, W. M., Voorhorst, W. G. M., Kluskens, L. D., Dijkgraaf, M., van der Oost, J. & Siezen, R., 2001, In : Methods in Enzymology. 330, p. 383-393

Research output: Contribution to journalArticleAcademicpeer-review

76 Citations (Scopus)

The archaeal TFIIE homologue facilitates transcription initiation by enhancing TATA-box recognition

Bell, S. D., Brinkman, A. B., van der Oost, J. & Jackson, S. P., 2001, In : Embo Reports. 2, p. 133-138

Research output: Contribution to journalArticleAcademicpeer-review

TATA-Box Binding Protein
TATA Box
Polytetrafluoroethylene
Transcription
Archaeal Genome

The catalytic potency of ß-glucosidase from Pyroccus furiosus in the direct glucosylation reaction

de Roode, B. M., van der Meer, T. D., Kaper, T., Franssen, M. C. R., van der Padt, A., van der Oost, J. & Boom, R. M., 2001, In : Enzyme and Microbial Technology. 29, p. 621-624

Research output: Contribution to journalArticleAcademicpeer-review

Glucosidases
Enzymes
Glucose
Temperature
Buffers
603 Citations (Scopus)

The complete genome of the Crenarchaeote Sulfolobus solfataricus P2

She, Q., Singh, R. K., Confalonieri, F., Zivanovic, Y., Allard, G., Awayez, M. J., Chan-Weiher, C. C. Y., Clausen, I. G., Curtis, B. A., de Moors, A., Heikamp-de Jong, I. & van der Oost, J., 2001, In : Proceedings of the National Academy of Sciences of the United States of America. 95, p. 7835-7840

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Crenarchaeota
DNA replication
genome
cell cycle
molecular motor proteins
57 Citations (Scopus)

The NADH oxidase from Pyrococcus furiosus: implications for the protection of anaerobic hyperthermophiles against oxidative stress

Ward, D. E., Donnelly, C., Mullendore, M. E., van der Oost, J., de Vos, W. M. & Crane III, E. J., 2001, In : European Journal of Biochemistry. 268, p. 5816-5823

Research output: Contribution to journalArticleAcademicpeer-review

Pyrococcus furiosus
Oxidative stress
Oxidative Stress
Genes
Genome
46 Citations (Scopus)

The Phosphoglucose Isomerase from the Hyperthermophilic Archaeon Pyrococcus furiosus is a Unique Glycolytic Enzyme that belongs to the Cupin Superfamily

Verhees, C. H., Huynen, M. A., Ward, D. E., Schiltz, E., de Vos, W. M. & van der Oost, J., 2001, In : Journal of Biological Chemistry. 276, p. 40926-40932

Research output: Contribution to journalArticleAcademicpeer-review

Pyrococcus furiosus
Glucose-6-Phosphate Isomerase
Archaea
Genes
Enzymes
26 Citations (Scopus)

The ß-glucosidase CelB from Pyrococcus furiosus: Production by Escherichia coli, purification, and in vitro evolution

Lebbink, J. H. G., Kaper, T., Kengen, S. W. M., van der Oost, J. & de Vos, W. M., 2001, In : Methods in Enzymology. 330, p. 364-379

Research output: Contribution to journalArticleAcademicpeer-review

2000

A BAC library and paired-PCR approach to mapping and completing the genome sequence of Sulfolobus solfataricus P2 : an EC perspective

She, Q., Confalonieri, F., Zivanovic, Y., Medina, N., Billault, A., Awayez, M. J., Thi-Ghoc, H. P., Thi-Pham, B. T., van der Oost, J., Duguet, M. & Garrett, R. A., 2000, In : Dna sequence. 11, p. 183-136

Research output: Contribution to journalArticleAcademicpeer-review

30 Citations (Scopus)

Activity and stability of hyperthermophilic enzymes : a comparative study on two archaeal b-glycosidases

Pouwels, J., Moracci, M., Cobucci-Ponzano, B., Perugino, G., van der Oost, J., Kaper, T., Lebbink, J. H. G., de Vos, W. M., Ciaramella, M. & Rossi, M., 2000, In : Extremophiles. 4, p. 157-164

Research output: Contribution to journalArticleAcademicpeer-review