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Research Output 1996 2020

2011

Microcanon : wat je beslist moet weten over microbiologie

Smit, H., van Doorn, J., van der Oost, J., Reijnders, W. & Willemsen, P. T. J., 2011, Diemen: Veen Magazines. 246 p. (Wetenschappelijke Bibliotheek van Natuurwetenschap&Techniek; no. 109)

Research output: Book/ReportBookAcademic

9 Citations (Scopus)

Occurrence of L-iduronic acid and putative D-glucuronyl C5-epimerases in prokaryotes

Raedts, J. G. J., Kengen, S. W. M. & van der Oost, J., 2011, In : Glycoconjugate Journal. 28, 2, p. 57-66

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Iduronic Acid
Racemases and Epimerases
Glycosaminoglycans
Polysaccharides
Animals

Opkomende infectieziekten, ongenode gasten uit verre streken

Moormann, R. J. M., Smit, H., van Doorn, J., van der Oost, J., Reijnders, W. & Willemsen, P. T. J., 2011, Microcanon. Smit, H. (ed.). Diemen, 3 p. (Wetenschappelijke bibliotheek; no. 109).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Overleven: De strijd om het bestaan

van der Oost, J., 2011, Microcanon. Smit, H., Reijnders, W., van Doorn, J., van der Oost, J. & Willemsen, P. (eds.). Diemen: NVVM, 288 p.

Research output: Chapter in Book/Report/Conference proceedingChapterPopular

331 Citations (Scopus)

Structural basis for CRISPR RNA-guided DNA recognition by Cascade

Jore, M. M., Lundgren, N. M. J., van Duijn, E., Bultema, J. B., Westra, E. R., van der Oost, J., Brouns, S. J. J. & Beijer, M. R., 2011, In : Nature Structural and Molecular Biology. 18, 5, p. 529-536

Research output: Contribution to journalArticleAcademicpeer-review

Clustered Regularly Interspaced Short Palindromic Repeats
Guide RNA
RNA
Smegmamorpha
Ribonucleoproteins
248 Citations (Scopus)

Structures of the RNA-guided surveillance complex from a bacterial immune system

Wiedenheft, B., Jore, M. M., Brouns, S. J. J. & van der Oost, J., 2011, In : Nature. 477, p. 486-489

Research output: Contribution to journalArticleAcademicpeer-review

Clustered Regularly Interspaced Short Palindromic Repeats
Immune System
RNA
Base Pairing
Nucleic Acids
37 Citations (Scopus)

Synthesis of non-natural carbohydrates from glycerol and aldehydes in a one-pot four-enzyme cascade reaction

Babich, L., Hartog, L., Falcicchio, P. & van der Oost, J., 2011, In : Green Chemistry. 13, 10, p. 2895-2900

Research output: Contribution to journalArticleAcademicpeer-review

Carbohydrates
aldehyde
Aldehydes
Glycerol
carbohydrate

Variatie en adaptatie: Lifestyle van micro-organismen

van der Oost, J., 2011, Microcanon. Smit, H., Reijnders, W., van Doorn, J., van der Oost, J. & Willemsen, P. (eds.). Diemen: NVVM, 288 p.

Research output: Chapter in Book/Report/Conference proceedingChapterPopular

2010
4 Citations (Scopus)

Fidelity in Archaeal Information Processing

de Koning, B., Blombach, F., Brouns, S. J. J. & van der Oost, J., 2010, In : Archaea : an international microbiological journal. 2010, 960298.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Genome Size
information processing
Archaea
Eukaryota
DNA Replication
9 Citations (Scopus)

Functional study on GTP hydrolysis by the GTP-binding protein from Sulfolobus solfataricus, a member of the HflX family

Huang, B., Wu, H., Hao, N., Blombach, F., van der Oost, J., Li, X., Zhang, X. C. & Rao, Z., 2010, In : Journal of Biochemistry. 148, 1, p. 103-113

Research output: Contribution to journalArticleAcademicpeer-review

Sulfolobus solfataricus
GTP Phosphohydrolases
Guanosine Triphosphate
GTP-Binding Proteins
Hydrolysis
148 Citations (Scopus)

H-NS-mediated repression of CRISPR-based immunity in Escherichia coli K12 can be relieved by the transcription activator LeuO

Westra, E. R., Pul, Ü., Heidrich, N., Jore, M. M., Lundgren, N. M. J., Stratmann, T., Wurm, R., Raine, A., Mescher, M., van Heereveld, L., Mastop, M., Wagner, E. G. H., Schnetz, K., van der Oost, J., Wagner, R. & Brouns, S. J. J., 2010, In : Molecular Microbiology. 77, 6, p. 1380-1393

Research output: Contribution to journalArticleAcademicpeer-review

Clustered Regularly Interspaced Short Palindromic Repeats
Escherichia coli K12
Immunity
Hot Temperature
CRISPR-Cas Systems
37 Citations (Scopus)

"Hot standards" for the thermoacidophilic archaeon Sulfolobus solfataricus

Zaparty, M., Esser, D., Gertig, S., Haferkamp, P., Kouril, T., Sierocinski, P., Pham, T. K., Manica, A., Reimann, J., Schreiber, K., Teichmann, D., van Wolferen, M. E., von Jan, M., Wieloch, P., Albers, S. V., Driessen, A. J. M., Klenk, H. P., Schleper, C., Schomburg, D., van der Oost, J. & 2 others, Wright, P. C. & Siebers, B., 2010, In : Extremophiles. 14, 1, p. 119-142

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Sulfolobus
Sulfolobus solfataricus
Metabolomics
Systems Biology
Archaea
3 Citations (Scopus)

Hot Transcriptomics

Walther, J., Sierocinski, P. & van der Oost, J., 2010, In : Archaea : an international microbiological journal. 2010, 14 p., 897585.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
microarray technology
transcriptomics
Technology
Archaea
transcriptome
82 Citations (Scopus)

Hydrogen production by hyperthermophilic and extremely thermophilic bacteria and archaea: mechanisms for reductant disposal

Verhaart, M. R. A., Bielen, A. A. M., van der Oost, J., Stams, A. J. M. & Kengen, S. W. M., 2010, In : Environmental Technology. 31, 8&9, p. 993-1003

Research output: Contribution to journalArticleAcademicpeer-review

thermophilic bacterium
Reducing Agents
Hydrogen production
Hydrogen
Bacteria
11 Citations (Scopus)

Identification of modules in Aspergillus niger by gene co-expression network analysis

van den Berg, R. A., Braaksma, M., van der Veen, D., van der Werf, M. J., Punt, P. J., van der Oost, J. & de Graaff, L. H., 2010, In : Fungal Genetics and Biology. 47, 6, p. 539-550

Research output: Contribution to journalArticleAcademicpeer-review

Aspergillus niger
Gene Expression
Transcription Factors
Genes
Binding Sites
12 Citations (Scopus)

Molecular characterization of the glucose isomerase from the thermophilic bacterium Fervidobacterium gondwanense

Kluskens, L. D., Zeilstra, J. B., Geerling, A. C. M., de Vos, W. M. & van der Oost, J., 2010, In : Environmental Technology. 31, 10, p. 1083-1090

Research output: Contribution to journalArticleAcademicpeer-review

xylose isomerase
thermophilic bacterium
Bacteria
glucose
ion
3 Citations (Scopus)

NMR characterization of a 264-residue hyperthermostable endo-ß-1,3-glucanase

Ippel, J. H., Koutsopoulos, S., Nabuurs, S. M., van Berkel, W. J. H., van der Oost, J. & van Mierlo, C. P. M., 2010, In : Biochemical and Biophysical Research Communications. 391, 1, p. 370-375

Research output: Contribution to journalArticleAcademicpeer-review

Nuclear magnetic resonance
Calcium
Glucan Endo-1,3-beta-D-Glucosidase
Temperature
Chemical shift
27 Citations (Scopus)

Pyrophosphate as a central energy carrier in the hydrogen-producing extremely thermophilic Caldicellulosiruptor saccharolyticus

Bielen, A. A. M., Willquist, K., Engman, J., van der Oost, J., van Niel, E. W. J. & Kengen, S. W. M., 2010, In : FEMS Microbiology Letters. 307, 1, p. 48-54

Research output: Contribution to journalArticleAcademicpeer-review

Pyrophosphatases
Hydrogen
Orthophosphate Dikinase Pyruvate
Adenosine Triphosphate
Phosphofructokinases
19 Citations (Scopus)

Quantitative Proteomic Analysis of Sulfolobus solfataricus Membrane Proteins

Pham, T. K., Sierocinski, P., van der Oost, J. & Wright, P. C., 2010, In : Journal of Proteome Research. 9, 2, p. 1165-1172 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Sulfolobus solfataricus
Proteomics
Membrane Proteins
Proteins
Membranes

RNA in defense: CRISPRs protect prokaryotes against mobile genetic elements

Jore, M. M., Brouns, S. J. J. & van der Oost, J., 2010, RNA Worlds: From Life’s Origins to Diversity in Gene Regulation. Atkins, J. F., Gesteland, R. F. & Cech, T. R. (eds.). New York, U.S.A.: Cold Spring Harbor Laboratory Press, p. 231-242 361 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Clustered Regularly Interspaced Short Palindromic Repeats
Interspersed Repetitive Sequences
RNA
MicroRNAs
DNA

Ruimteclub NASA doet spectaculaire vondst (interview met Prof. Dr. John van der Oost)

de Vreede, J. & van der Oost, J., 2010, In : AD Nieuws. 1 p.

Research output: Contribution to journalArticlePopular

14 Citations (Scopus)

Structure of the ribosome associating GTPase HflX

Wu, H., Sun, L., Blombach, F., Brouns, S. J. J., Snijders, A. P. L., Lorenzen, K., van den Heuvel, R. H. H., Heck, A. J. R., Fu, S., Li, X., Zhang, X. C., Rao, Z. & van der Oost, J., 2010, In : Proteins : Structure, Function, and Bioinformatics. 78, 3, p. 705-713

Research output: Contribution to journalArticleAcademicpeer-review

Large Ribosome Subunits
Guanosine
GTP Phosphohydrolases
Ribosomes
Switches

'Zoeken naar Leven' (Labyrint twittersessie met Prof. Dr. John van der Oost)

van der Oost, J., 2010

Research output: Non-textual formDigital or Visual Products

2009
66 Citations (Scopus)

Carboxylic ester hydrolases from hyperthermophiles

Levisson, M., van der Oost, J. & Kengen, S. W. M., 2009, In : Extremophiles. 13, 4, p. 567-581

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Carboxylic Ester Hydrolases
Esters
Enzymes
Archaea
Esterases
18 Citations (Scopus)

Cofactor engineering of Lactobacillus brevis alcohol dehydrogenase by computational design

Machielsen, M. P., Looger, L. L., Raedts, J. G. J., Dijkhuizen, S., Hummel, W., Henneman, H. G., Daussmann, T. & van der Oost, J., 2009, In : Engineering in Life Sciences. 9, 1, p. 38-44

Research output: Contribution to journalArticleAcademicpeer-review

Lactobacillus brevis
Alcohol Dehydrogenase
NAD
Alcohols
NADP
59 Citations (Scopus)

Correlated mutation analyses on super-family alignments reveal functionally important residues

Kuipers, R. K., Joosten, H. J., Verwiel, E., Paans, J., Akerboom, J., van der Oost, J., Leferink, N. G. H., van Berkel, W. J. H., Vriend, G. & Schaap, P. J., 2009, In : Proteins : Structure, Function, and Bioinformatics. 76, 3, p. 608-616

Research output: Contribution to journalArticleAcademicpeer-review

Mutation
Enzymes
Sequence Alignment
Intramolecular Transferases
Isocitrate Lyase
304 Citations (Scopus)

CRISPR-based adaptive and heritable immunity in prokaryotes

van der Oost, J., Jore, M. M., Westra, E. R., Lundgren, N. M. J. & Brouns, S. J. J., 2009, In : Trends in Biochemical Sciences. 34, 8, p. 401-407

Research output: Contribution to journalArticleAcademicpeer-review

Clustered Regularly Interspaced Short Palindromic Repeats
Adaptive Immunity
DNA
Guide RNA
Interspersed Repetitive Sequences
27 Citations (Scopus)

Crystal structure and biochemical properties of a novel thermostable esterase containing an immunoglobulin-like domain

Levisson, M., Sun, L., Hendriks, S. N. A., Swinkels, P., Akveld, T., Bultema, J. B., Barendregt, A., van den Heuvel, R. H. H., Dijkstra, B. W., van der Oost, J. & Kengen, S. W. M., 2009, In : Journal of Molecular Biology. 385, 3, p. 949-962

Research output: Contribution to journalArticleAcademicpeer-review

Esterases
Serine
Thermotoga maritima
Paraoxon
Organophosphates
25 Citations (Scopus)

Crystal structure of a family 16 endoglucanase from the hyperthermophile Pyrococcus furiosus--structural basis of substrate recognition

Ilari, A., Fiorillo, A., Angelaccio, S., Florio, R., Chiaraluce, R., van der Oost, J. & Consalvi, V., 2009, In : FEBS Journal. 276, 4, p. 1048-1058

Research output: Contribution to journalArticleAcademicpeer-review

Pyrococcus furiosus
Cellulase
Substrate Specificity
Glucan Endo-1,3-beta-D-Glucosidase
Crystal structure
19 Citations (Scopus)

Effect of O2 concentrations on Sulfolobus solfataricus P2

Simon, G., Walther, J., Zabeti, N., Combet-Blanc, Y., Auria, R., van der Oost, J. & Casalot, L., 2009, In : FEMS Microbiology Letters. 299, 2, p. 255-260

Research output: Contribution to journalArticleAcademicpeer-review

Sulfolobus solfataricus
Growth
Oxygen
Respiratory System
Oligonucleotide Array Sequence Analysis
27 Citations (Scopus)

Identification of an ortholog of the eukaryotic RNA polymerase III subunit RPC34 in Crenarchaeota and Thaumarchaeota suggests specialization of RNA polymerases for coding and non-coding RNAs in Archaea

Blombach, F., Makarova, K. S., Marrero, J., Siebers, B., Koonin, E. V. & van der Oost, J., 2009, In : Biology Direct. 4, p. 39 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Crenarchaeota
RNA Polymerase III
Untranslated RNA
Archaea
DNA-Directed RNA Polymerases
9 Citations (Scopus)

Improving low-temperature activity of Sulfolobus acidocaldarius 2-keto-3-deoxygluconate aldolase

Wolterink-van Loo, S., Siemerink, M. A. J., Perrakis, G., Kaper, T., Kengen, S. W. M. & van der Oost, J., 2009, In : Archaea : an international microbiological journal. 2, 4, p. 233-239

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Sulfolobus acidocaldarius
fructose-bisphosphate aldolase
Temperature
Glyceraldehyde
mutants
110 Citations (Scopus)

Prokaryotic homologs of Argonaute proteins are predicted to function as key components of a novel system of defense against mobile genetic elements

Makarova, K. S., Wolf, Y. I., van der Oost, J. & Koonin, E. V., 2009, In : Biology Direct. 4, p. 29 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Argonaute Proteins
Interspersed Repetitive Sequences
nucleases
Guide RNA
RNA Interference
19 Citations (Scopus)

RNAi: prokaryotes get in on the act

van der Oost, J. & Brouns, S. J. J., 2009, In : Cell. 139, 5, p. 863-865

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access
Clustered Regularly Interspaced Short Palindromic Repeats
Archaea
RNA Interference
Guide RNA
Pyrococcus furiosus
16 Citations (Scopus)

Role of multiprotein bridging factor 1 in archaea: bridging the domains?

de Koning, B., Blombach, F., Wu Hao, Brouns, S. J. J. & van der Oost, J., 2009, In : Biochemical Society Transactions. 37, 1, p. 52-57

Research output: Contribution to journalArticleAcademicpeer-review

Archaea
Transcription
Genes
Eukaryota
TATA-Box Binding Protein
25 Citations (Scopus)

SulfoSYS (Sulfolobus Systems Biology): towards a silicon cell model for the central carbohydrate metabolism of the archaeon Sulfolobus solfataricus under temperature variation

Albers, S. V., Birkeland, N. K., Driessen, A. J. M., Gertig, S., Haferkamp, P., Klenk, H. P., Kouril, T., Manica, A., Pham, T. K., Ruoff, P., Schleper, C., Schomburg, D., Sharkey, K., Siebers, B., Sierocinski, P., Steur, R., van der Oost, J., Westerhoff, H. V., Wieloch, P., Wright, P. C. & 1 others, Zaparty, M., 2009, In : Biochemical Society Transactions. 37, 1, p. 58-64

Research output: Contribution to journalArticleAcademicpeer-review

Sulfolobus
Sulfolobus solfataricus
Systems Biology
Archaea
Carbohydrate Metabolism
16 Citations (Scopus)

The crystal structure of a hyperthermoactive exopolygalacturonase from Thermotoga maritima reveals a unique tetramer

Pijning, T., van Pouderoyen, G., Kluskens, L. D., van der Oost, J. & Dijkstra, B. W., 2009, In : FEBS Letters. 583, 22, p. 3665-3670

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
exopolygalacturonase
Thermotoga maritima
Polygalacturonase
Crystal structure
Oligomerization
2008
16 Citations (Scopus)

Characterization of a thermostable dihydrodipicolinate synthase from Thermoanaerobacter tengcongensis

Wolterink-van Loo, S., Levisson, M., Cabrières, M. C., Franssen, M. C. R. & van der Oost, J., 2008, In : Extremophiles. 12, 3, p. 461-469 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

4-hydroxy-tetrahydrodipicolinate synthase
Thermoanaerobacter
Lysine
Escherichia coli
Genes
12 Citations (Scopus)

Divergent roles of CprK paralogues from Desulfitobacterium hafniense in activating gene expression

Gabor, K., Sene, K. H., Smidt, H., de Vos, W. M. & van der Oost, J., 2008, In : Microbiology. 154, p. 3686-3696

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Desulfitobacterium
Gene Expression
Cyclic AMP Receptor Protein
Genome
Interspersed Repetitive Sequences
117 Citations (Scopus)

Hydrogenomics of the extremely thermophilic bacterium Caldicellulosiruptor saccharolyticus

van de Werken, H. J. G., Verhaart, M. R. A., Vanfossen, A. L., Willquist, K., Lewis, D. L., Nichols, J. D., Goorissen, H. P., Mongodin, E. F., Nelson, K. E., van Niel, E. W. J., Stams, A. J. M., Ward, D. E., de Vos, W. M., van der Oost, J., Kelly, R. M. & Kengen, S. W. M., 2008, In : Applied and Environmental Microbiology. 74, 21, p. 6720-6729

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Caldicellulosiruptor saccharolyticus
thermophilic bacterium
thermophilic bacteria
Hydrogen
Ferredoxins
31 Citations (Scopus)

Laboratory evolution of Pyrococcus furiosus alcohol dehydrogenase to improve the production of (2S,5S)-hexanediol at moderate temperatures

Machielsen, M. P., Leferink, N. G. H., Hendriks, A., Brouns, S. J. J., Hennemann, H., Daussmann, T. & van der Oost, J., 2008, In : Extremophiles. 12, 4, p. 587-594

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Pyrococcus furiosus
Alcohol Dehydrogenase
Temperature
Agrochemicals
Mutation
38 Citations (Scopus)

Molecular basis of halorespiration control by CprK, a CRP-FNR type transcriptional regulator

Levy, C., Pike, K., Heyes, D., Joyce, M. G., Gabor, K., Smidt, H., van der Oost, J. & Leys, D., 2008, In : Molecular Microbiology. 70, 1, p. 151-167

Research output: Contribution to journalArticleAcademicpeer-review

Ligands
Desulfitobacterium
Thermodynamics
Disulfides
Oxidation-Reduction
1173 Citations (Scopus)

Small CRISPR RNAs guide antiviral defense in prokaryotes

Brouns, S. J. J., Jore, M. M., Lundgren, M., Westra, E. R., Slijkhuis, R. J., Snijders, A. P., Dickman, M. J., Makarova, K. S., Koonin, E. V. & van der Oost, J., 2008, In : Science. 321, 5891, p. 960-964

Research output: Contribution to journalArticleAcademicpeer-review

Guide RNA
Antiviral Agents
Viruses
CRISPR-Associated Proteins
RNA
22 Citations (Scopus)

Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily

Brouns, S. J. J., Barends, T. R. M., Worm, P., Akerboom, J., Turnbull, A. P., Salmon, L. & van der Oost, J., 2008, In : Journal of Molecular Biology. 379, 2, p. 357-371 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Hydro-Lyases
Catalysis
Enzymes
Ions
Catalytic Domain
44 Citations (Scopus)

The non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) of Sulfolobus solfataricus: a key-enzyme of the semi-phosphorylative branch of the Entner-Doudoroff pathway

Ettema, T. J. G., Ahmed, H., Geerling, A. C. M., van der Oost, J. & Siebers, B., 2008, In : Extremophiles. 12, 1, p. 75-88

Research output: Contribution to journalArticleAcademicpeer-review

Sulfolobus solfataricus
Glyceraldehyde-3-Phosphate Dehydrogenases
Archaea
Glyceraldehyde 3-Phosphate
Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)
62 Citations (Scopus)

Transcriptome analysis of infection of the archaeon Sulfolobus solfataricus with Sulfolobus turreted icosahedral virus

Ortmann, A. C., Walther, J., Brumfield, S. K., McInnerney, K., Brouns, S. J. J., van de Werken, H. J. G., Bothner, B., Douglas, T., van der Oost, J. & Young, M. J., 2008, In : Journal of Virology. 82, 10, p. 4874-4883

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Sulfolobus
Sulfolobus solfataricus
Archaea
Gene Expression Profiling
transcriptomics
2007
58 Citations (Scopus)

A global transcriptional regulator in Thermococcus kodakaraensis controls the expression levels of both glycolytic and gluconeogenic enzyme-encoding genes

Kanai, T., Akerboom, A. P., Takedomi, S., van de Werken, H. J. G., Blombach, F., van der Oost, J., Murakami, T., Atomi, H. & Imanaka, T., 2007, In : Journal of Biological Chemistry. 282, 46, p. 33659-33670

Research output: Contribution to journalArticleAcademicpeer-review

Thermococcales
Thermococcus
Gene encoding
Genes
Enzymes
23 Citations (Scopus)

Biochemical and structural exploration of the catalytic capacity of Sulfolobus KDG aldolases

Wolterink-van Loo, S., van Eerde, A., Siemerink, M. A. J., Akerboom, A. P., Dijkstra, B. W. & van der Oost, J., 2007, In : Biochemical Journal. 403, p. 421-430

Research output: Contribution to journalArticleAcademicpeer-review

Aldehyde-Lyases
Sulfolobus
Sulfolobus acidocaldarius
Glyceraldehyde 3-Phosphate
Substrates
53 Citations (Scopus)

Characterization and structural modeling of a new type of thermostable esterase from Thermotoga maritima

Levisson, M., van der Oost, J. & Kengen, S. W. M., 2007, In : FEBS Journal. 274, 11, p. 2832-2842

Research output: Contribution to journalArticleAcademicpeer-review

Thermotoga maritima
Esterases
Carboxylesterase
Esters
Geobacillus stearothermophilus
7 Citations (Scopus)
Thermotoga maritima
Bombyx
Crystallization
silkworms
crystallization