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John Groten

prof.dr.ir.

    1987 …2018
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    Fingerprint Dive into the research topics where John Groten is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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    Network Recent external collaboration on country level. Dive into details by clicking on the dots.

    Research Output 1987 2018

    Novel insights in the molecular mechanisms of action of retinoids and their potential repercussions on breast cancer cell proliferation

    Miro Estruch, I., 2018, Wageningen: Wageningen University. 280 p.

    Research output: Thesis › internal PhD, WU › Academic

    The effects of all-trans retinoic acid on estrogen receptor signaling in the estrogen-sensitive MCF/BUS subline

    Miro Estruch, I., de Haan, L. H. J., Melchers, D., Houtman, R., Louisse, J., Groten, J. P. & Rietjens, I. M. C. M., Apr 2018, In : Journal of Receptors and Signal Transduction. 38, 2, p. 112-121

    Research output: Contribution to journal › Article › Academic › peer-review

    Open Access
    Tretinoin
    Estrogen Receptors
    Estrogens
    Retinoic Acid Receptors
    Gene expression
    4 Citations (Scopus)

    Characterization of the differential coregulator binding signatures of the Retinoic Acid Receptor subtypes upon (ant)agonist action

    Miro Estruch, I., Melchers, D., Houtman, R., de Haan, L. H. J., Groten, J. P., Louisse, J. & Rietjens, I. M. C. M., 2017, In : Biochimica et Biophysica Acta. Proteins & Proteomics. 1865, 9, p. 1195-1206

    Research output: Contribution to journal › Article › Academic › peer-review

    Retinoic Acid Receptors
    Ants
    Ligands
    Assays
    Retinoids
    11 Citations (Scopus)

    Cell proliferation and modulation of interaction of estrogen receptors with coregulators induced by ERa and ERB agonists

    Evers, N. M., van den Berg, J. H. J., Wang, S., Melchers, D., Houtman, J., de Haan, L. H. J., Ederveen, A. G. H., Groten, J. P. & Rietjens, I., 2014, In : Journal of Steroid Biochemistry and Molecular Biology. 143, p. 376-385

    Research output: Contribution to journal › Article › Academic › peer-review

    Cell proliferation
    Estrogen Receptors
    Cell Proliferation
    Modulation
    Assays

    Factors influencing ER subtype-mediated cell proliferation and apoptosis

    Evers, N. M., 2014, Wageningen: Wageningen University. 243 p.

    Research output: Thesis › internal PhD, WU › Academic

    Estrogen Receptors
    Estrogens
    Cell Proliferation
    Apoptosis
    Ligands

    Projects 2007 2018

    Assessment of phospho-signaling in retinal tissues in vitro and in vivo by kinase activity profiling.

    Roy, A., Groten, J. & Rietjens, I.

    1/10/18 → …

    Project: PhD

    The cross talk of retinoic acid receptors with estrogen receptors and the consequences for cell proliferation and breast cancer risks.

    Miro Estruch, I., Groten, J., Louisse, J. & Rietjens, I.

    1/10/13 → 19/06/18

    Project: PhD

    The role of ERa and ERß in the risk benefit analysis of mixtures of estrogens; Effect of differential ER expression on cell proliferation and apoptosis.

    Evers, N., Groten, J. & Rietjens, I.

    1/09/09 → 13/06/14

    Project: PhD

    Development of improved and new in vitro assays for detecting genotoxic and non-genotoxic carcinogenic potential of chemicals in the discovery phase of drug development.

    Groten, J. & Rietjens, I.

    1/02/07 → 1/03/11

    Project: PhD