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Research Output 1988 2020

2016

Stress tolerance and lifespan in C. elegans are modulated by natural allelic variation in CMK-1

Snoek, L. B., Sterken, M. G., Bevers, R. P. J., Volkers, J. M., van 't Hof, A., Brenchley, R., Lehner, B., Cossins, A. & Kammenga, J. E., 31 Mar 2016.

Research output: Contribution to conferencePosterAcademic

stress tolerance
genes
heat stress
mutants
loci
35 Citations (Scopus)

The Genetic Basis of Natural Variation in Caenorhabditis elegans Telomere Length

Cook, D. C., Zdraljevic, S., Tanny, R. E., Seo, B., Riccardi, D. D., Noble, L. M., Rockman, M. V., Alkema, M. J., Braendle, C., Kammenga, J. E., Wang, J., Kruglyak, L., Felix, M. A., Lee, J. & Andersen, E. C., 2016, In : Genetics. 204, 1, p. 371-383

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Telomere
Caenorhabditis elegans
Genomic Instability
Oligosaccharides
Oligonucleotides

Transcriptional regulation in stress recovery of Caenorhabditis elegans

Snoek, L. B., Sterken, M. G., Bevers, R. P. J., Riksen, J. A. G. & Kammenga, J. E., 31 Mar 2016.

Research output: Contribution to conferencePosterAcademic

Caenorhabditis elegans
quantitative trait loci
heat stress
inbred lines
stress response

Two complementary introgression line libraries in C. elegans

Sterken, M. G., van Creij, J., Riksen, J. A. G., Tan, B., Snoek, L. B. & Kammenga, J. E., 30 Mar 2016. 2 p.

Research output: Contribution to conferenceAbstractAcademic

introgression
genome
genetic background
loci
heat stress
2015

Acute stress resistance, DR and Lifespan in a multi-parent recombinant inbred line panel

Stastna, J., Snoek, L. B., Volkers, J. M., Riksen, J. A. G., Vujakovic, A., Schulenburg, H., Kammenga, J. E. & Harvey, S., 2015.

Research output: Contribution to conferencePosterProfessional

A decrease in movement at a defined moment in life predicts death

Jovic, K., Bartels, R., Volkers, J. M., Sterken, M. G., Snoek, L. B. & Kammenga, J. E., 2015.

Research output: Contribution to conferencePoster

37 Citations (Scopus)

Caenorhabditis elegans DAF-16/FOXO Transcription Factor and Its Mammalian Homologs Associate with Age-Related Disease

Hesp, K., Smant, G. & Kammenga, J. E., 2015, In : Experimental Gerontology. 72, p. 1-7

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Caenorhabditis elegans
Insulin-Like Growth Factor I
Transcription Factors
Insulin
Heat-Shock Response

Dietary restriction is not a universal means of prolonging the lifespan in nematode Caenorhabditis elegans

Stastna, J., Snoek, L. B., Kammenga, J. E. & Harvey, S. C., 2015.

Research output: Contribution to conferencePosterProfessional

11 Citations (Scopus)

Genotype-dependent lifespan effects in peptone deprived Caenorhabditis elegans

Stastna, J., Snoek, L. B., Kammenga, J. E. & Harvey, S. C., 2015, In : Scientific Reports. 5, 9 p., 16259.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
peptones
Caenorhabditis elegans
dietary restriction
genotype
introgression

On predicting regulatory genes by analysis of functional networks in C. elegans

Valba, O. V., Nechaev, S., Sterken, M. G., Snoek, L. B., Kammenga, J. E. & Vasieva, O., 2015, In : BioData Mining. 8, 1, 16 p., 33.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Regulator Genes
Genes
Quantitative Trait Loci
Gene
Gene Expression

Opposite immune responses in Caenorhabditis elegans caused by a single gene, the neuropeptide receptor gene npr-1

Nakad, R., Snoek, L. B., Yang, W., Dierking, K., Rosenstiel, P. C., Kammenga, J. E. & Schulenburg, H., 2015, Proceedings of the 20th International C. elegans Meeting. Los Angeles, USA, p. 62-62

Research output: Chapter in Book/Report/Conference proceedingAbstract

Caenorhabditis elegans
immune response
avoidance behavior
Bacillus thuringiensis
Pseudomonas aeruginosa
42 Citations (Scopus)

Remarkably divergent regions punctuate the genome assembly of the Caenorhabditis elegans Hawaiian strain CB4856

Thompson, O. A., Snoek, L. B., Nijveen, H., Sterken, M. G., Volkers, R. J. M., Brenchley, R., van 't Hof, A., Bevers, R. P. J., Cossins, A. R., Yanai, I., Hajnal, A., Schmid, T., Perkins, J. D., Spencer, D., Kruglyak, L., Andersen, E. C., Moerman, D. G., Hillier, L. W., Kammenga, J. E. & Waterston, R. H., 2015, In : Genetics. 200, 3, p. 975-989

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Caenorhabditis elegans
Nucleotides
Genome
Chromosomes
Cytoplasmic and Nuclear Receptors

Rictor limits temperature-dependent dauer formation by controlling intestine-neuron signaling

O'Donnell, M., Kammenga, J. E. & Sengupta, P., 2015.

Research output: Contribution to conferencePosterProfessional

Stress tolerance and lifespan in C. elegans are modulated by natural allelic variation in cmk-1

Sterken, M. G., Snoek, L. B., Bevers, R. P. J., Volkers, R. J. M., van 't Hof, A., Brenchley, R., Lehner, B., Cossins, A. & Kammenga, J. E., 2015, Proceedings of Molecular Biology of Ageing 2015. p. 134-134

Research output: Chapter in Book/Report/Conference proceedingAbstract

stress tolerance
genes
loci
heat stress
gene expression

Stress tolerance and lifespan in C. elegans are modulated by natural allelic variation in cmk-1

Sterken, M. G., Snoek, L. B., Bevers, R. P. J., Volkers, J. M., van 't Hof, A., Brenchley, R., Lehner, B., Cossins, A. & Kammenga, J. E., 2015.

Research output: Contribution to conferencePoster

15 Citations (Scopus)

Systemic Regulation of RAS/MAPK Signaling by the Serotonin Metabolite 5-HIAA

Schmid, T., Snoek, L. B., Fröhli, E., van der Bent, M. L., Kammenga, J. E. & Hajnal, A., 2015, In : Plos Genetics. 11, 5, 16 p., e1005236.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
5-hydroxyindoleacetic acid
amine oxidase (flavin-containing)
Hydroxyindoleacetic Acid
Monoamine Oxidase
serotonin
54 Citations (Scopus)

The laboratory domestication of Caenorhabditis elegans

Sterken, M. G., Snoek, L. B., Kammenga, J. E. & Andersen, E. C., 2015, In : Trends in Genetics. 31, 6, p. 224-231

Research output: Contribution to journalArticleAcademicpeer-review

Caenorhabditis elegans
Alleles
Biomedical Research
Outcome Assessment (Health Care)
Domestication

Transcriptional regulation in stress recovery of Caenorhabditis elegans

Sterken, M. G., Snoek, L. B., Bevers, R. P. J., Riksen, J. A. G. & Kammenga, J. E., 2015.

Research output: Contribution to conferencePoster

Caenorhabditis elegans
quantitative trait loci
heat stress
inbred lines
stress response
2014
16 Citations (Scopus)

A heritable antiviral RNAi response limits Orsay virus infection in Caenorhabditis elegans N2

Sterken, M. G., Snoek, L. B., Bosman, K. J., Daamen, J., Riksen, J. A. G., Bakker, J., Pijlman, G. P. & Kammenga, J. E., 2014, In : PLoS ONE. 9, 2, e89760.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Caenorhabditis elegans
Virus Diseases
RNA Interference
RNA interference
Viruses
18 Citations (Scopus)

A rapid and massive gene expression shift marking adolescent transition in C. elegans

Snoek, L. B., Sterken, M. G., Volkers, R. J. M., Klatter, M., Bosman, K. J., Bevers, R. P. J., Riksen, J. A. G., Smant, G., Cossins, A. R. & Kammenga, J. E., 2014, In : Scientific Reports. 4, 3912.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Gene Expression
Genes
Chromatin Assembly and Disassembly
Caenorhabditis elegans
Life Cycle Stages

Bar-1 loss-of-function causes a developmental delay in intertwined with a DAF-16 stress response

Sterken, M. G., van der Bent, M. L., Volkers, R. J. M., Riksen, J. A. G., Schmid, T., Hajnal, A., Kammenga, J. E. & Snoek, L. B., 2014, Proceedings of the Berlin C. elegans Meeting 2014. p. 241-241

Research output: Chapter in Book/Report/Conference proceedingAbstract

Wnt Signaling Pathway
Ovum
Gene Expression
Catenins
Genes

Dissecting the genetic architecture of resistance to orsay virus infection in C. elegans

Sterken, M. G., Wang, Y., Snoek, L. B., Volkers, R. J. M., Riksen, J. A. G., Bosman, K. J., Pijlman, G. P. & Kammenga, J. E., 2014, Proceedings of Evolutionary Biology of Caenorhabditis and other Nematodes. p. 111-111

Research output: Chapter in Book/Report/Conference proceedingAbstract

Virus Diseases
Viruses
Chromosomes
Host-Pathogen Interactions
RNA Interference

Dissecting the genetic architecture of resistance to orsay virus infection in C. elegans

Sterken, M. G., Wang, Y., Snoek, L. B., Volkers, R. J. M., Riksen, J. A. G., Bosman, K. J., Pijlman, G. P. & Kammenga, J. E., 2014, Proceedings of PhD Spring School Host-Microbe Interactomics. p. 12-12

Research output: Chapter in Book/Report/Conference proceedingAbstract

Virus Diseases
Viruses
Chromosomes
Host-Pathogen Interactions
RNA Interference

Genome wide mapping of stress-response and ageing pathway regulators

Sterken, M. G., Snoek, L. B., Bevers, R. P. J., Volkers, R. J. M., van 't Hof, A., Brenchley, R., van Cleef, E., Bartels, R., Laven, Y., Riksen, J. A. G., Cossins, A. R. & Kammenga, J. E., 2014, Proceedings of the Berlin C. elegans Meeting. p. 49-49

Research output: Chapter in Book/Report/Conference proceedingAbstract

Open Access
stress response
heat stress
genome
loci
genes

Identifying modifiers of Wnt and EGFR/RAS/MAPK signaling through quantitative C. elegans genetics

Maxeiner, S., Schmid, T., Snoek, L. B., Rodriguez Sanchez, M., Largey, F., van der Bent, L., Kammenga, J. E. & Hajnal, A. F., 2014, Proceedings of the FEBS-EMBO 2014. Vol. 281. p. 474-474

Research output: Chapter in Book/Report/Conference proceedingAbstract

Mutation
Modifier Genes
Gene Knockdown Techniques
Catenins
Vulva

Lifespan and the Effects of Dietary Restriction in a Multi-Parent Recombinant Inbred Line Panel in Caenorhabditis elegans

Stastna, J., Snoek, L. B., Volkers, R. J. M., Riksen, J. A. G., Kammenga, J. E. & Harvey, S., 2014, Proceedings of the Berlin C. elegans Meeting 2014. p. 240-240

Research output: Chapter in Book/Report/Conference proceedingAbstract

dietary restriction
Caenorhabditis elegans
inbred lines
transgressive segregation
epistasis
10 Citations (Scopus)

Loss-of-function of b-catenin bar-1 slows development and activates the Wnt pathway in Caenorhabditis elegans

van der Bent, M. L., Sterken, M. G., Volkers, J. M., Riksen, J. A. G., Schmid, T., Hajnal, A., Kammenga, J. E. & Snoek, L. B., 2014, In : Scientific Reports. 4, 7 p., 4926.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Catenins
Wnt Signaling Pathway
Caenorhabditis elegans
Transcriptome
Mutation

Natural variation in lifespan and dietary restriction effects in a multi-parent recombinant inbred line panel in Caenorhabditis elegans

Stastna, J., Snoek, L. B., Volkers, R. J. M., Riksen, J. A. G., Schulenburg, H., Kammenga, J. E. & Harvey, S. C., 2014, Proceedings of The 2014 Evolution of Caenorhabditis and Other Nematodes Conference. p. 32-32

Research output: Chapter in Book/Report/Conference proceedingAbstract

dietary restriction
Caenorhabditis elegans
inbred lines
quantitative trait loci
alleles

Nematode endogenous small RNA pathways

Hoogstrate, S. W., Volkers, R. J. M., Sterken, M. G., Kammenga, J. E. & Snoek, L. B., 2014, In : Worm. 3, 1, 10 p., e28234.

Research output: Contribution to journalArticleAcademicpeer-review

Nematoda
RNA
RNA interference
gene expression regulation
Caenorhabditis elegans

Next-gen genetical genomics; RNA-sequencing of a new multi-parent recombinant inbred line population of Caenorhabditis elegans

Snoek, L. B., Volkers, R. J. M., Nijveen, H., Sterken, M. G., Riksen, J. A. G., Braeckman, B., Schulenburg, H. J. G. & Kammenga, J. E., 2014, Proceedings of Evolutionary Biology of Caenorhabditis and other Nematodes. p. 77-77

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

Caenorhabditis elegans
inbred lines
sequence analysis
RNA
genomics

Polymorphic regions and genes affecting gene transcription regulation of stress response and prolonged lifespan

Sterken, M. G., Snoek, L. B., Bevers, R. P. J., Volkers, R. J. M., van 't Hof, A., Brenchley, R., van Cleef, E., Bartels, R., Laven, Y., Riksen, J. A. G., Valba, O., Chavali, S., Lang, B., Francesconi, M., Bot, J., Nechaev, S., Vasieva, O., Babu, M., Lehner, B., Cossins, A. & 1 others, Kammenga, J. E., 2014, Proceedings of Evolutionary Biology of Caenorhabditis and other Nematodes. p. 33-33

Research output: Chapter in Book/Report/Conference proceedingAbstract

stress response
transcription (genetics)
genes
gene expression
introgression

The effects of development on gene expression in L4 Caenorhabditis elegans larvae

Riksen, J. A. G., Snoek, L. B., Sterken, M. G., Volkers, R. J. M., Klatter, M., Bosman, K., Bevers, R. P. J., Smant, G., Cossins, A. R. & Kammenga, J. E., 2014, Proceedings of the Berlin C. elegans Meeting. p. 215-215

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

Caenorhabditis elegans
gene expression
larvae
genes
time series analysis

The mysterious role of the C.elegans nuclear hormone receptor NPR-1 in pathogen defense

Nakad, R., Snoek, L. B., Dierking, K., Yang, W., Kammenga, J. E. & Schulenburg, H., 2014, Proceedings of the Berlin C. elegans Meeting 2014. p. 194-194

Research output: Chapter in Book/Report/Conference proceedingAbstract

hormone receptors
Caenorhabditis elegans
avoidance behavior
Bacillus thuringiensis
microorganisms
21 Citations (Scopus)

Widespread Genomic Incompatibilities in Caenorhabditis elegans

Snoek, L. B., Orbidans, H. E., Stastna, J., Aartse, A., Rodriguez Sanchez, M., Riksen, J. A. G., Kammenga, J. E. & Harvey, S. C., 2014, In : G3 : Genes Genomes Genetics. 4, 10, p. 1813-1823

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Quantitative Trait Loci
Caenorhabditis elegans
Ovum
Reproductive Isolation
Phenotype
15 Citations (Scopus)

WormQTL HD—a web database for linking human disease to natural variation data in C. elegans

van der Velde, K. J., de Haan, M., Zych, K., Arends, D., Snoek, L. B., Kammenga, J. E., Jansen, R. C., Swertz, M. A. & Li, Y., 2014, In : Nucleic acids research. 42, D1, p. D794-D801

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Databases
Genome-Wide Association Study
Phenotype
Genes
National Human Genome Research Institute (U.S.)

Worm variation made accessible: Take your shopping cart to store, link, and investigate!

Snoek, L. B., van der Velde, K. J., Li, Y., Jansen, R. C., Swertz, M. A. & Kammenga, J. E., 2014, In : Worm. 3, 1, 7 p., e28357.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
carts
Caenorhabditis elegans
Caenorhabditis
genetic variation
genotype
2013

Benut variatie modelworm beter (interview met dr. ir. J.E. Kammenga en dr.ir. L.B. Snoek)

Kammenga, J. E., Snoek, L. B. & van Maanen, G., 2013, In : Bionieuws. 23, 14, p. 1-1

Research output: Contribution to journalArticleProfessional

Open Access

Comparative proteomics and transcriptomics in two C. elegans wild-type strains

Kamkina, P., Daube, M., Roschitzki, B., Grossmann, J., Volkers, J. M., Snoek, L. B., Kammenga, J. E., Schrimpf, S. & Hengartner, M., 2013, Proceedings of the 19th International C.elegans Meeting, 26-30 June 2013, Los Angeles, California, USA. p. 399-399

Research output: Chapter in Book/Report/Conference proceedingAbstract

29 Citations (Scopus)

Gene-environment and protein degradation signatures characterize genomic and phenotypic diversity in wild Caenorhabditis elegans populations

Volkers, J. M., Snoek, L. B., van Hellenberg Hubar, C. J., Coopman, R., Chen, W., Yang, W., Sterken, M. G., Schulenburg, H., Braeckman, B. & Kammenga, J. E., 2013, In : BMC Biology. 11, 13 p., 93.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Caenorhabditis elegans
protein degradation
Proteolysis
genomics
genotype

Gene-environments interactions drive genomics and transcriptomic diversity in wild Caenorhabditis elegans populations

Volkers, J. M., Snoek, L. B., van Hellenberg Hubar, C. J., Coopman, R., Chen, W., Sterken, M. G., Schulenburg, H., Braekman, B. & Kammenga, J. E., 2013, Proceedings of the 19th International C.elegans Meeting, 26-30 June 2013, Los Angeles, California, USA. p. 317-317

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

Genetic basis underlying differential susceptibility to bacteria in Caenorhabditis elegans

Wang, Z., Herman, M., Snoek, L. B. & Kammenga, J. E., 2013, Proceedings of the 19th International C.elegans Meeting, 26-30 June 2013, Los Angeles, California, USA. p. 184-184

Research output: Chapter in Book/Report/Conference proceedingAbstract

20 Citations (Scopus)

Genetic mapping of variation in dauer larvae development in growing populations of Caenorhabditis elegans

Green, J. W. M., Snoek, L. B., Kammenga, J. E. & Harvey, S. C., 2013, In : Heredity. 111, p. 306-313 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Caenorhabditis elegans
Larva
Quantitative Trait Loci
Population
Neuropeptide Y Receptors
4 Citations (Scopus)

Maintenance of muscle myosin levels in adult C. elegans requires both the double bromodomain protein BET-1 and sumoylation

Fisher, K., Gee, F., Wang, S., Xue, F., Knapp, S., Philpott, M., Wells, C., Rodriguez, M., Snoek, L. B., Kammenga, J. E. & Poulin, G., 2013, In : Biology Open. 2, p. 1354-1363

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Sumoylation
Myosins
myosin
Mitogen-Activated Protein Kinase Kinases
Muscle

Natural variation in Monoamine Oxidase A modulates RAS/MAPK pathway activity during C. elegans vulval development

Schmid, T., Snoek, L. B., Rodriguez, M., van der Bent, L., Despot Slade, E., Kammenga, J. E. & Hajnal, A., 2013, Proceedings of the 5th EMBO meeting, 21-24 September 2013, Amsterdam, the Netherlands. p. 49-49

Research output: Chapter in Book/Report/Conference proceedingAbstract

Monoamine Oxidase
Gene Transfer Techniques
Mutation
Biogenic Amines
Penetrance

Orsay Virus infection dynamics in Caenorhabditis elegans

Sterken, M. G., Snoek, L. B., Bosman, K., Daamen, J., Riksen, J. A. G., Bakker, J., Pijlman, G. P. & Kammenga, J. E., 2013, Proceedings of the 5th EMBO meeting 2013, 21-24 September 2013, Amsterdam, the Netherlands. p. 113-114

Research output: Chapter in Book/Report/Conference proceedingAbstract

Caenorhabditis elegans
Virus Diseases
RNA Interference
Viruses
Infection

Orsay virus replication kinetics in C. elegans strain Bristol N2

Sterken, M. G., Bosman, K., Snoek, L. B., Daamen, J., Riksen, J. A. G., Bakker, J., Pijlman, G. P. & Kammenga, J. E., 2013, Proceedings of the 19th International C.elegans Meeting, 26-30 June 2013, Los Angeles, California, USA. p. 341-341

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

Studying the effect of natural variation on protein abundance in C. elegans

Singh, K. D., Kamkina, P., Roschitzki, B., Elvin, M., Rodriguez, M., Poulin, G., Snoek, L. B., Kammenga, J. E., Schrimpf, S. & Hengartner, M., 2013, Proceedings of the 19th International C.elegans Meeting, 26-30 June 2013, Los Angeles, California, USA. p. 399-399

Research output: Chapter in Book/Report/Conference proceedingAbstract

The sudden transcriptional switch to adulthood in L4 stage C. elegans

Snoek, L. B., Sterken, M. G., Volkers, J. M., Klatter, M., Bosman, K., Bevers, R. P. J., Riksen, J. A. G. & Kammenga, J. E., 2013, Proceedings of the 19th International C.elegans Meeting, 26-30 June 2013, Los Angeles, California, USA. p. 331-331

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

Uncovering genotype variation of Wnt signaling in C. elegans

Rodriguez, M., Snoek, L. B., Schmid, T., Samadi, N., van der Bent, L., Hajnal, A. & Kammenga, J. E., 2013, Proceedings of the 19th International C.elegans Meeting, 26-30 June 2013, Los Angeles, California, USA. p. 330-331

Research output: Chapter in Book/Report/Conference proceedingAbstract

Uncovering hidden Wnt/beta-catenin enhancer in Caenorhabditis elegans

Rodriguez, M., Snoek, L. B., Schmid, T., Riksen, J. A. G., Samadi, N., van der Bent, L., Grolleman, J., Hajnal, A. & Kammenga, J. E., 2013, Proceedings of 1st Annual Meeting, COST FA 1208, 09-11 October 2013, Birnam, Scotland. p. 55-55

Research output: Chapter in Book/Report/Conference proceedingAbstract

Caenorhabditis elegans
beta Catenin
Genotype
Catenins
Wnt Signaling Pathway