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Research Output 1988 2019

2019
1 Citation (Scopus)

A multi-parent recombinant inbred line population of C. elegans allows identification of novel QTLs for complex life history traits

Snoek, B. L., Volkers, J. M., Nijveen, H., Petersen, C., Dirksen, P., Sterken, M. G., Nakad, R., Riksen, J. A. G., Rosenstiel, P. C., Stastna, J. J., Braekman, B. P., Harvey, S. C., Schulenburg, H. & Kammenga, J. E., 12 Mar 2019, In : BMC Biology. 17, 17 p., 24.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
life history trait
inbred lines
quantitative trait loci
genotype
life history

Evolution of hatching stimulant perception in Potato Cyst Nematode

Vlaar, L., Rahimi, M., Rodriguez, A., Helder, J., Goverse, A., Kammenga, J. E. & Bouwmeester, H. J., 8 Apr 2019.

Research output: Contribution to conferencePosterAcademic

Gene expression profile in a C. elegans model of Alpha-Synuclein with variable natural genetic background and their phenotypic variations

Wang, Y., Snoek, L. B., Sterken, M. G., Riksen, J. A. G., Stastna, J. J., Kammenga, J. E. & Harvey, S., May 2019.

Research output: Contribution to conferencePosterAcademic

Synucleins
alpha-Synuclein
Transcriptome
Genotype
Genes

Genetic background modifies phenotypic and transcriptional responses in a C. elegans model of α-synuclein toxicity

Wang, Y. A., Snoek, B. L., Sterken, M. G., Riksen, J. A. G., Stastna, J. J., Kammenga, J. E. & Harvey, S. C., 20 Mar 2019, In : BMC Genomics. 20, 1, 12 p., 232.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Synucleins
Caenorhabditis elegans
Gene Expression
Neurodegenerative Diseases
Phenotype

Genetic variation associated with Alpha-synuclein pathology in Caenorhabditis elegans

Wang, Y. A., 2019, Wageningen: Wageningen University. 144 p.

Research output: Thesisinternal PhD, WUAcademic

Open Access

Selection and gene flow shape niche-associated variation in pheromone response

Lee, D., Zdraljevic, S., Cook, D. E., Frézal, L., Hsu, J-C., Sterken, M. G., Riksen, J. A. G., Wang, J., Kammenga, J. E., Braendle, C., Félix, M-A., Schroeder, F. C. & Andersen, E. C., 1 Oct 2019, In : Nature Ecology & Evolution. 3, p. 1455-1463

Research output: Contribution to journalArticleAcademicpeer-review

pheromone
pheromones
gene flow
niche
niches

Sex-specific viral susceptibility of Caenorhabditis elegans nematodes

van Sluijs, L., Liu, J., Schrama, M., van Hamond, S., Vromans, S., Pijlman, G. P. & Kammenga, J. E., 22 May 2019.

Research output: Contribution to conferencePosterAcademic

Caenorhabditis elegans
Nematoda
gender
viruses
pathogens

The hypoxia-response pathway modulates RAS/MAPK–mediated cell fate decisions in Caenorhabditis elegans

Maxeiner, S., Grolleman, J., Schmid, T., Kammenga, J. E. & Hajnal, A., 24 May 2019, In : Life Science Alliance. 2, 3, e201800255.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Caenorhabditis elegans
hypoxia
Oxygen
oxygen
Animals
2018

Caenorhabditis elegans males and hermaphrodites differ in susceptibility upon Orsay virus infection

van Sluijs, L., Liu, J. (ed.), Schrama, M. (ed.), van Hamond, S. (ed.), Pijlman, G. P. (ed.) & Kammenga, J. E. (ed.), 5 Jul 2018.

Research output: Contribution to conferencePosterAcademic

Caenorhabditis elegans
Virus Diseases
Eating
Viruses
Viral Load
6 Citations (Scopus)

Forward and reverse genetics approaches to uncover metabolic aging pathways in Caenorhabditis elegans

Gao, A. W., uit de Bos, J., Sterken, M. G., Kammenga, J. E., Smith, R. L. & Houtkooper, R. H., Sep 2018, In : Biochimica et Biophysica Acta. Molecular Basis of Disease. 1864, 9A, p. 2697-2706 36 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Reverse Genetics
Caenorhabditis elegans
Metabolic Networks and Pathways
Gene-Environment Interaction
Research

Genetic variation causes differential viral susceptibilities in the model organism Caenorhabditis elegans

van Sluijs, L., Sterken, M. G., Wang, Y., Ritmahan, W., Gultom, M., Pankok, F., Blokhina, T., Riksen, J. A. G., Volkers, J. M., Snoek, L. B., Pijlman, G. P. & Kammenga, J. E., 23 May 2018.

Research output: Contribution to conferencePosterAcademic

Caenorhabditis elegans
Virus Diseases
Clustered Regularly Interspaced Short Palindromic Repeats
Viruses
Quantitative Trait Loci
6 Citations (Scopus)
Open Access
Tylenchoidea
Meloidogyne incognita
root-knot nematodes
Arabidopsis
chromosome mapping
Meloidogyne incognita
root-knot nematodes
chromosome mapping
Arabidopsis thaliana
genome

Identification of natural variants that influence behavioral responses to ethanol in C. elegans

Bettinger, J., Kammenga, J. E., Mathies, L. & Davies, A., 4 Mar 2018.

Research output: Contribution to conferencePosterAcademic

4 Citations (Scopus)

Natural genetic variation in C. elegans identified genomic loci controlling metabolite levels

Gao, A. W., Sterken, M. G., Uit De Bos, J., van Creij, J., Kamble, R., Snoek, B. L., Kammenga, J. E. & Houtkooper, R. H., 14 Aug 2018, In : Genome Research. 28, 8, p. 1296-1308

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Fatty Acids
Caenorhabditis elegans
Homeostasis
Food
Gene-Environment Interaction

Natural genetic variation in C. elegans identified genomic loci controlling metabolite levels

Sterken, M. G., Gao, A. W., uit de Bos, J. (ed.), van Creij, J. W. (ed.), Kamble, R. (ed.), Snoek, L. B. (ed.), Kammenga, J. E. (ed.) & Houtkooper, R. H. (ed.), Jul 2018.

Research output: Contribution to conferencePosterAcademic

metabolites
genomics
genetic variation
loci
Caenorhabditis elegans
4 Citations (Scopus)

Natural plant hormones cytokinins increase stress resistance and longevity of Caenorhabditis elegans

Kadlecová, A., Jirsa, T., Novák, O., Kammenga, J., Strnad, M. & Voller, J., Apr 2018, In : Biogerontology. 19, 2, p. 109-120

Research output: Contribution to journalArticleAcademicpeer-review

Kinetin
Cytokinins
Plant Growth Regulators
Caenorhabditis elegans
Oxidative Stress

Population complexity trumps model complexity in understanding trait variation

Sterken, M. G., Snoek, L. B., Bevers, R. P. J., Volkers, J. M., Riksen, J. A. G. & Kammenga, J. E., 16 May 2018.

Research output: Contribution to conferencePosterAcademic

gene expression
introgression
inbred lines
quantitative trait loci
loci

Predicting individual differences in viral susceptibility caused by natural genetic variation within species

van Sluijs, L., Sterken, M. G., Wang, Y., Ritmahan, W., Gultom, M., Pankok, F., Blokhina, T., Riksen, J. A. G., Volkers, J. M., Snoek, L. B., Pijlman, G. P. & Kammenga, J. E., 17 Jun 2018.

Research output: Contribution to conferencePosterAcademic

genetic polymorphism
introgression
genetic variation
quantitative trait loci
viral load
18 Citations (Scopus)

Quantifying resilience of humans and other animals

Scheffer, M., Bolhuis, J. E., Borsboom, D., Buchman, T. G., Gijzel, S. M. W., Goulson, D., Kammenga, J. E., Kemp, B., van de Leemput, I. A., Levin, S., Martin, C. M., Melis, R. J. F., van Nes, E. H., Romero, L. M. & Olde Rikkert, M. G. M., 20 Nov 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 47, p. 11883-11890

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
animal
adaptive management
physiology
livestock
time series
5 Citations (Scopus)

Rictor/TORC2 mediates gut-to-brain signaling in the regulation of phenotypic plasticity in C. elegans

O’Donnell, M. P., Chao, P-H., Kammenga, J. E. & Sengupta, P., 7 Feb 2018, In : Plos Genetics. 14, 2, e1007213.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
phenotypic plasticity
brain
intestines
digestive system
food
2017

A point-of-no-return leading to death in C. elegans

Jovic, K., Sterken, M. G., Grilli, J., Bevers, R. P. J., Rodriguez, M., Riksen, J. A. G., Allesina, S., Kammenga, J. E. & Snoek, L. B., 2017.

Research output: Contribution to conferencePosterAcademic

4 Citations (Scopus)

AraQTL - Workbench and Archive for systems genetics in Arabidopsis thaliana

Nijveen, H., Ligterink, W., Keurentjes, J. J. B., Loudet, O., Long, J., Sterken, M. G., Prins, P., Hilhorst, H. W., De Ridder, D., Kammenga, J. E. & Snoek, B. L., 2017, In : The Plant Journal. 89, 6, p. 1225-1235

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Quantitative Trait Loci
Arabidopsis
quantitative trait loci
Arabidopsis thaliana
Genomics
8 Citations (Scopus)

Contribution of trans regulatory eQTL to cryptic genetic variation in C. elegans

Snoek, B. L., Sterken, M. G., Bevers, R. P. J., Volkers, R. J. M., van 't Hof, A., Brenchley, R., Riksen, J. A. G., Cossins, A. & Kammenga, J. E., 2017, In : BMC Genomics. 18, 15 p., 500.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Hot Temperature
Gene Expression
Genes
Heat-Shock Response
Temperature

Death as a tipping point-Merging disciplines to predict lifespan

Jovic, K., Grilli, J., Snoek, L. B., Allesina, S. & Kammenga, J. E., 31 Aug 2017.

Research output: Contribution to conferencePosterAcademic

Genetic Phenomena
Genes
Sociology
Gene Regulatory Networks
Systems Analysis
9 Citations (Scopus)

Disparate gain and loss of parasitic abilities among nematode lineages

Holterman, M., Karegar, A., Mooijman, P., van Megen, H., van den Elsen, S., Vervoort, M. T. W., Quist, C. W., Karssen, G., Decraemer, W., Opperman, C. H., Bird, D. M., Kammenga, J., Goverse, A., Smant, G. & Helder, H., 2017, In : PLoS ONE. 12, 9, 18 p., e0185445.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Aptitude
Nematoda
Biodiversity
Parasites
parasites
5 Citations (Scopus)

Genetic variation in neurodegenerative diseases and its accessibility in the modelorganism Caenorhabditis elegans

Wang, Y., Kammenga, J. E. & Harvey, S. C., 2017, In : Human Genomics. 11, 12.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Caenorhabditis elegans
Neurodegenerative Diseases
Phenotype
Regulator Genes

Microarray profiling of gene expression in Alpha-Synuclein aggregations and its alteration by natural genetic variation in Caenorhabditis elegans

Wang, Y., Snoek, L. B., Sterken, M. G., Riksen, J. A. G., Cook, D., Tanny, R. E., Andersen, E. C., Kammenga, J. E. & Harvey, S., 2017.

Research output: Contribution to conferencePosterAcademic

alpha-Synuclein
Caenorhabditis elegans
Gene Expression Profiling
Neurodegenerative Diseases
Transgenes
5 Citations (Scopus)

Ras/MAPK Modifier Loci Revealed by eQTL in Caenorhabditis elegans

Sterken, M. G., van Bemmelen-van der Plaat, L., Riksen, J. A., Rodriguez, M., Schmid, T., Hajnal, A., Kammenga, J. E. & Snoek, B. L., 2017, In : G3 : Genes Genomes Genetics. 7, 9, p. 3185-3193

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Caenorhabditis elegans
Mutation
Modifier Genes
Chromosome Mapping
Gene Expression Regulation
2 Citations (Scopus)

reGenotyper: Detecting mislabeled samples in genetic data

Zych, K., Snoek, B. L., Elvin, M., Rodriguez, M., Van Der Velde, K. J., Arends, D., Westra, H-J., Swertz, M. A., Poulin, G., Kammenga, J. E., Breitling, R., Jansen, R. C. & Li, Y., 2017, In : PLoS ONE. 12, 2, e0171324.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Labels
Genotype
Cleaning
genotype
Throughput
6 Citations (Scopus)

Temporal dynamics of gene expression in heat-stressed Caenorhabditis elegans

Jovic, K., Sterken, M. G., Grilli, J., Bevers, R. P. J., Rodriguez Sanchez, M., Riksen, J. A. G., Allesina, S., Kammenga, J. E. & Snoek, L. B., 11 Dec 2017, In : PLoS ONE. 12, 12, 16 p., e0189445.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Caenorhabditis elegans
Gene expression
heat stress
Hot Temperature
heat
19 Citations (Scopus)

The background puzzle: how identical mutations in the same gene lead to different disease symptoms

Kammenga, J. E., 16 Oct 2017, In : FEBS Journal. 284, 20, p. 3362-3373

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Genes
Mutation
Penetrance
Epigenomics
Genetic Background

The molecular basis of natural variation in cold stress response in Caenorhabditis elegans

Stastna, J., Snoek, L. B., Nei, N., Wang, Y., Riksen, J. A. G., Kammenga, J. E. & Harvey, S. C., 21 Jun 2017.

Research output: Contribution to conferencePosterAcademic

Caenorhabditis elegans
cold stress
temperature
genes
lipid composition
1 Citation (Scopus)

Why do Individuals Differ in Viral Susceptibility? A Story Told by Model Organisms

van Sluijs, L., Pijlman, G. P. & Kammenga, J. E., 2017, In : Viruses. 9, 10, 284.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Individuality
Viruses
Caenorhabditis elegans
Genetic Polymorphisms
Virus Diseases
2016

A new approach to aging research: Death as a tipping point

Jovic, K., Grilli, J., Snoek, L. B., Allesina, S. & Kammenga, J. E., 2016.

Research output: Contribution to conferencePosterAcademic

Genetic Phenomena
Gene Regulatory Networks
Human Genome
Systems Analysis
Ecology

A new approach to aging research: Death as a tipping point

Jovic, K., Grilli, J., Snoek, L. B., Allesina, S. & Kammenga, J. E., 2016.

Research output: Contribution to conferencePosterAcademic

Genetic Phenomena
Gene Regulatory Networks
Human Genome
Systems Analysis
Ecology

Building towards a multi-dimensional genetic architecture in Caenorhabditis elegans

Sterken, M. G., 2016, Wageningen: Wageningen University. 167 p.

Research output: Thesisinternal PhD, WUAcademic

Open Access
Caenorhabditis elegans
introgression
inbred lines
genotype
loci
14 Citations (Scopus)

Contrasting invertebrate immune defense behaviors caused by a single gene, the Caenorhabditis elegans neuropeptide receptor gene npr-1

Nakad, R., Snoek, B., Yang, W., Ellendt, S., Schneider, F., Mohr, T. G., Rösingh, L., Masche, A. C., Rosenstiel, P. C., Dierking, K., Kammenga, J. E. & Schulenburg, H., 1 Dec 2016, In : BMC Genomics. 17, 1, 20 p., 280.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Neuropeptide Receptors
Caenorhabditis elegans
Invertebrates
Bacillus thuringiensis
Quantitative Trait Loci

Death as a tipping point: A new approach to aging research

Jovic, K., Grilli, J., Snoek, L. B., Allesina, S. & Kammenga, J. E., 2016, p. 140-140.

Research output: Contribution to conferencePosterAcademic

Caenorhabditis elegans
Research
Genetic Phenomena
Gene Regulatory Networks
Human Genome

Discovery and identification of novel anti-viral alleles in Caenorhabditis elegans

van Sluijs, L., Sterken, M. G., Wang, Y., Snoek, L. B., Volkers, J. M., Riksen, J. A. G., Pijlman, G. P. & Kammenga, J. E., 2 Apr 2016.

Research output: Contribution to conferenceAbstractAcademic

Caenorhabditis elegans
alleles
genes
loci
quantitative trait loci

Dissection of the genetic architecture in Caenorhabditis elegans underlying protein misfolding pathological mechanisms

Wang, Y., Sterken, M. G., Kammenga, J. E. & Harvey, S. C., May 2016, p. 236-236.

Research output: Contribution to conferencePosterAcademic

Caenorhabditis elegans Proteins
Parkinson Disease
Dissection
Proteostasis Deficiencies
Alleles
Open Access
Individuality
Research
12 Citations (Scopus)

Mixture toxicity: Linking approaches from ecological and human toxicology

van Gestel, C. A. M. (ed.), Jonker, M. J. (ed.), Kammenga, J. E. (ed.), Laskowski, R. (ed.) & Svendsen, C. (ed.), 19 Apr 2016, CRC Press. 269 p.

Research output: Book/ReportBook editingAcademic

toxicology
Toxicology
Toxicity
risk assessment
toxicity
8 Citations (Scopus)

Natural genetic variation differentially affects the proteome and transcriptome in Caenorhabditis elegans

Kamkina, P., Snoek, L. B., Grossmann, J., Volkers, R. J. M., Sterken, M. G., Daube, M., Roschitzki, B., Fortes, C., Schlapbach, R., Roth, A., von Mering, C., Hengartner, M. O., Schrimpf, S. P. & Kammenga, J. E., 2016, In : Molecular and Cellular Proteomics. 15, 5, p. 1670-1680

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Caenorhabditis elegans
Proteome
Transcriptome
Proteins
Genes
7 Citations (Scopus)

Natural Genetic Variation Influences Protein Abundances in C. elegans Developmental Signalling Pathways

Singh, K. D., Roschitzki, B., Snoek, B., Grossmann, J., Zheng, X., Elvin, M., Kamkina, P., Schrimpf, S. P., Poulin, G. B., Kammenga, J. E., Hengartner, M. O. & Rutherford, S. (ed.), 2016, In : PLoS ONE. 11, 3, e0149418.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
genetic variation
quantitative trait loci
Proteins
proteins
Quantitative Trait Loci

Natural Variation in Acute Stress Resistance, DR and Lifespan in a Multi-Parent Recombinant Inbred Line Panel in C. elegans

Stastna, J., Snoek, L. B., Riksen, J. A. G., Vujakovic, A., Schulenburg, H., Kammenga, J. E. & Harvey, S. C., May 2016.

Research output: Contribution to conferencePosterAcademic

stress tolerance
inbred lines
quantitative trait loci
stress response
dietary restriction

Natural Variation in Stress Response in C. elegans using a Novel Recombinant Inbred Panel

Stastna, J., Snoek, L. B., Riksen, J. A. G., Vujakovic, A., Schulenburg, H., Kammenga, J. E. & Harvey, S. C., Jul 2016.

Research output: Contribution to conferenceAbstractAcademic

Stress and recovery, natural variation, gene expression and QTL

Snoek, L. B., Jovic, K., Sterken, M. G. & Kammenga, J. E., 2016.

Research output: Contribution to conferenceAbstractAcademic

quantitative trait loci
heat stress
gene expression
inbred lines
stress response

Stress tolerance and lifespan in C. elegans are modulated by natural allelic variation in CMK-1

Snoek, L. B., Sterken, M. G., Bevers, R. P. J., Volkers, J. M., van 't Hof, A., Brenchley, R., Lehner, B., Cossins, A. & Kammenga, J. E., 31 Mar 2016.

Research output: Contribution to conferencePosterAcademic

stress tolerance
genes
heat stress
mutants
loci