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Research Output 1983 2020

2011
66 Citations (Scopus)
Labeling
Membrane Proteins
Milk
Proteins
Milk Proteins

Human ERa and ERb splice variants: understanding their domain structure in relation to their biological roles in breast cancer cell proliferation

Sotoca Covaleda, A. M., Vervoort, J. J. M., Rietjens, I. & Gustafsson, J. A., 2011, Biochemistry. Ekinci, D. (ed.). Rijeka, Crotia: InTech, p. 142-160

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

18 Citations (Scopus)

Identification and localization of the structural proteins of anguillid herpesvirus 1

van Beurden, S. J., Leroy, B., Wattiez, R., Haenen, O. L. M., Boeren, S., Vervoort, J. J. M., Peeters, B. P. H., Rottier, P. J. M., Engelsma, M. Y. & Vanderplasschen, A. F., 2011, In : Veterinary Research. 42, 15 p., 105.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Herpesviridae
structural proteins
capsid
Proteins
proteins
51 Citations (Scopus)

Metabolic engineering of geranic acid in maize to achieve fungal resistance is compromised by novel glycosylation patterns

Yang, T., Stoopen, G., Yalpani, N., Vervoort, J. J. M., de Vos, R., Voster, A., Verstappen, F. W. A., Bouwmeester, H. J. & Jongsma, M. A., 2011, In : Metabolic Engineering. 13, 4, p. 414-425

Research output: Contribution to journalArticleAcademicpeer-review

Metabolic engineering
Glycosylation
Metabolic Engineering
Terpenes
Fungi
19 Citations (Scopus)

Physiologically based biokinetic (PBBK) model for safrole bioactivation and detoxification in rats

Martati, E., Boersma, M. G., Spenkelink, A., Khadka, D. B., Punt, A., Vervoort, J. J. M., van Bladeren, P. J. & Rietjens, I., 2011, In : Chemical Research in Toxicology. 24, 6, p. 818-834

Research output: Contribution to journalArticleAcademicpeer-review

Safrole
Detoxification
Rats
Metabolites
methyleugenol
26 Citations (Scopus)

Physiologically based biokinetic model of bioactivation and detoxification of the alkenylbenzene methyleugenol in rat

Al-Subeihi, A. A., Spenkelink, A., Rachmawati, N., Boersma, M. G., Punt, A., Vervoort, J. J. M., van Bladeren, P. J. & Rietjens, I. M. C. M., 2011, In : Toxicology in Vitro. 25, 1, p. 267-285

Research output: Contribution to journalArticleAcademicpeer-review

methyleugenol
Detoxification
Rats
Metabolites
Liver
77 Citations (Scopus)
Polyphenols
Metabolites
Spectroscopy
Ions
Glycosylation

Quantitative proteomics and transcriptomics addressing the estrogen receptor subtype-mediated effects in T47D breast cancer cells exposed to the phytoestrogen genistein

Sotoca Covaleda, A. M., Sollewijn Gelpke, M. D., Boeren, S., Ström, A., Gustafsson, J. A., Murk, A. J., Rietjens, I. M. C. M. & Vervoort, J. J. M., 2011, In : Molecular and Cellular Proteomics. 10, M110.002170.

Research output: Contribution to journalArticleAcademicpeer-review

Phytoestrogens
Estrogen Receptor alpha
Genistein
Estrogen Receptors
Proteomics
130 Citations (Scopus)

The Host Defense Proteome of Human and Bovine Milk

Hettinga, K. A., van Valenberg, H. J. F., de Vries, S. C., Boeren, S., van Hooijdonk, A. C. M., van Arendonk, J. A. M. & Vervoort, J. J. M., 2011, In : PLoS ONE. 6, 4, 8 p., e19433.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Human Milk
Proteome
breast milk
proteome
Milk
2010
67 Citations (Scopus)

An inter-laboratory comparison demonstrates that [H-1]-NMR metabolite fingerprinting is a robust technique for collaborative plant metabolomic data collection.

Ward, J. L., Baker, J. M., Miller, S. J., Deborde, C., Maucourt, M., Biais, B., Rolin, D., Moing, A., Moco, S. I. A., Vervoort, J. J. M., Lommen, A., Schafer, H., Humpfer, E. & Beale, M. H., 2010, In : Metabolomics. 6, 2, p. 263-273

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Metabolomics
Metabolites
Nuclear magnetic resonance
Multivariate Analysis
Nuclear magnetic resonance spectroscopy

Design and structural analysis of a thermostable nine-beta-stranded immunoglobulin scaffold.

de Roo, G., Francoijs, C. J. J., Ippel, J. H., Houtzager, E., Vijn, I. M. C., Burgers, K., Willebrands, W., Verwoerd, T. C., van der Linden, R., Vervoort, J. J. M. & Sijmons, P. C., 2010, In : Biocatalysis and Biotransformation. 28, 2, p. 99-107

Research output: Contribution to journalArticleAcademicpeer-review

Scaffolds (biology)
Scaffolds
Structural analysis
Immunoglobulins
Proteins
34 Citations (Scopus)

Identification of nevadensin as an important herb-based constituent inhibiting estragole bioactivation and physiology-based biokinetic modeling of its possible in vivo effect

Al-Husainy, W. A. A. M., Paini, A., Punt, A., Louisse, J., Spenkelink, B., Vervoort, J. J. M., Delatour, T., Scholz, G., Schilter, B., Adams, T. B., van Bladeren, P. J. & Rietjens, I., 2010, In : Toxicology and Applied Pharmacology. 245, 2, p. 179-190

Research output: Contribution to journalArticleAcademicpeer-review

Physiology
Sulfotransferases
Ocimum basilicum
Rats
Detoxification
17 Citations (Scopus)

LC-MS-SPE-NMR for the Isolation and Characterization of neo-Clerodane Diterpenoids from Teucrium luteum subsp. flavovirens

Castro, A., Moco, S. I. A., Coll, J. & Vervoort, J. J. M., 2010, In : Journal of Natural Products. 73, 5, p. 962-965

Research output: Contribution to journalArticleAcademicpeer-review

Teucrium
Clerodane Diterpenes
Diterpenes
Nuclear magnetic resonance
Molecules
67 Citations (Scopus)

Phase II Metabolism of Hesperetin by Individual UDP-Glucuronosyltransferases and Sulfotransferases and Rat and Human Tissue Samples

Brand, W., Boersma, M. G., Bik, H., Hoek-van den Hil, E. F., Vervoort, J. J. M., Barron, D., Meinl, W., Glatt, H., Williamson, G., van Bladeren, P. J. & Rietjens, I., 2010, In : Drug Metabolism and Disposition. 38, 4, p. 617-625 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Sulfotransferases
Glucuronosyltransferase
Glucuronides
Sulfates
Enzymes
28 Citations (Scopus)

Proteomic analysis of Chilo iridescent virus

Ince, I. A., Boeren, J. A., van Oers, M. M., Vervoort, J. J. M. & Vlak, J. M., 2010, In : Virology. 405, 1, p. 253-258

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Iridovirus
Proteomics
Invertebrates
Proteins
Ascoviridae
22 Citations (Scopus)

Proteomic analysis of Glossina pallidipes salivary gland hypertrophy virus virions for immune intervention in tsetse fly colonies

Kariithi, H. M., Ince, I. A., Boeren, S., Vervoort, J. J. M., Bergoin, M., van Oers, M. M., Abd-Alla, A. M. M. & Vlak, J. M., 2010, In : Journal of General Virology. 91, p. 3065-3074

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Tsetse Flies
Cytomegalovirus
Virion
Proteomics
Hypertrophy
38 Citations (Scopus)
Genistein
Luciferases
Reporter Genes
Gene expression
Estrogen Receptors

The proteome of Glossina pallidipes salivary gland hypertrophy virus (Hytrosaviridae) virions.

Ince, I. A., Kariithi, H. M., Boeren, S., Vervoort, J. J. M., Bergoin, M., Vlak, J. M., Abd-Alla, A. M. M. & van Oers, M. M., 2010.

Research output: Contribution to conferenceAbstractAcademic

Open Access

The proteome of Glossina pallipides Salivary Gland Hypertrophy Virus (Hytrosaviridae) virions

Ince, I. A., Kariithi, H. M., Boeren, S., Vervoort, J. J. M., Bergoin, M., Vlak, J. M., Abd-Alla, A. M. M. & van Oers, M. M., 2010, Proceedings of the 43rd Annual Meeting of the Society for Invertebrate pathology, Trabzon, Turkey, 11 - 15 July, 2010. Trabzon: Karadeniz Technical University (Turkey), p. 36-36

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

Unravelling the mechanism of differential biological responses induced by food-borne xeno- and phyto-estrogenic compounds

Sotoca Covaleda, A. M., 2010, [S.l.: S.n.. 186 p.

Research output: Thesisinternal PhD, WUAcademic

Open Access
Estrogen Receptors
Estrogens
Food
Cell Proliferation
Proteomics
2009
39 Citations (Scopus)

Characterization of Chinese Liquor Starter, ''Daqu", by Flavor Type with H-1 NMR-Based Nontargeted Analysis.

Wu, X. H., Zheng, X., Han, B. Z., Vervoort, J. J. M. & Nout, M. J. R., 2009, In : Journal of Agricultural and Food Chemistry. 57, 23, p. 11354-11359

Research output: Contribution to journalArticleAcademicpeer-review

Starters
Flavors
Fermentation
nuclear magnetic resonance spectroscopy
Magnetic Resonance Spectroscopy
48 Citations (Scopus)

Identification of in vitro phosphorylation sites in the Arabidopsis thaliana somatic embryogenesis receptor-like kinase

Karlova, R. B., Boeren, J. A., Kwaaitaal, M. A. C. J., Aker, J. C. M., Vervoort, J. J. M. & de Vries, S. C., 2009, In : Proteomics. 9, 2, p. 368-379

Research output: Contribution to journalArticleAcademicpeer-review

Phosphorylation
Brassinosteroids
Arabidopsis
Embryonic Development
Phosphotransferases
10 Citations (Scopus)

Iridoid and caffeoyl phenylethanoid glycosides of the endangered carnivorous plant Pinguicula lusitanica L. (Lentibulariaceae)

Grevenstuk, T., van der Hooft, J. J. J., Vervoort, J. J. M., de Waard, P. & Romano, A., 2009, In : Biochemical Systematics and Ecology. 37, 4, p. 285-289

Research output: Contribution to journalArticleAcademicpeer-review

Pinguicula
carnivorous plant
Lentibulariaceae
carnivorous plants
Glycosides
54 Citations (Scopus)

Plant Micrometabolomics: The Analysis of Endogenous Metabolites Present in a Plant Cell or Tissue.

Moco, S. I. A., Schneider, B. & Vervoort, J. J. M., 2009, In : Journal of Proteome Research. 8, 4, p. 1694-1703

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Plant Cells
Metabolites
Tissue
Technology
Microdissection

Proteomic analysis of Chilo iridescent virus

Ince, I. A., Boeren, S., van Oers, M. M., Vervoort, J. J. M. & Vlak, J. M., 2009, Abstract Book of the 42nd Annual Meeting of the Society for Invertebrate Pathology, Park City, Utah, USA, 16 - 20 August, 2009. Park City, Utah2009, p. 70-70

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

40 Citations (Scopus)

Quantitative structure-activity relationship modeling of the toxicity of organothiophosphate pesticides to Daphnia magna and Cyprinus carpio

Zvinavashe, E., Du, T., Griff, T., van den Berg, J. H. J., Soffers, A. E. M. F., Vervoort, J. J. M., Murk, A. J. & Rietjens, I., 2009, In : Chemosphere. 75, 11, p. 1531-1538

Research output: Contribution to journalArticleAcademicpeer-review

Organothiophosphates
Daphnia
Quantitative Structure-Activity Relationship
Carps
Pesticides
24 Citations (Scopus)

Recombinant expression and functional characterisation of regiospecific flavonoid glucosyltransferases from Hieracium pilosella L.

Witte, S., Moco, S. I. A., Vervoort, J. J. M., Matern, U. & Martens, S., 2009, In : Planta. 229, 5, p. 1135-1146

Research output: Contribution to journalArticleAcademicpeer-review

Pilosella officinarum
Glucosyltransferases
Inflorescence
glucosyltransferases
Glucosides
2008

Chemical investigation of Pinguicula lusitanica by HPLC-MS and HPLC-SPE-NMR

Grevenstuk, T., Van, D. H. J. J. J., Vervoort, J. J. M. & Romano, A., 2008, Proceedings of the 7th Joint Meeting of GA, AFERP, ASP, PSE & SIF, Athens, Greece, 3-8 August 2008. Vol. 74. p. 1101

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

Pinguicula
high performance liquid chromatography
extracts
evaporators
wild plants

Effectors, their targets and host responses in the pathosystem Cladosporium fulvum-tomato

de Wit, P. J. G. M., Stergiopoulos, I., van t Klooster, J. W., van Esse, H. P., Fradin, E. F., Ellendorff, U., Gabriëls, S. H. E. J., Stulemeijer, I. J. E., Bolton, M. D., Borrás-Hidalgo, O., Tameling, W. I. L., Abd-El-Haliem, A. M., van den Berg-Velthuis, G. C. M., Vervoort, J. J. M., Boeren, S., Joosten, M. H. A. J. & Thomma, B. P. H. J., 2008, Biology of Plant-Microbe Interactions CD. Lorito, M., Woo, S. L. & Scala, F. (eds.). St. Paul, MN, USA, p. np (Biology of Plant-Microbe Interactions; no. 6).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Identification of an apple juice compound directly in the H-1 spectrum of the mixture with hyphenated techniques and push button NMR: example fruit juice screening

Humpfer, E., Schafer, H., Vervoort, J. J. M., Hofmann, G., Mooertter, M., Keller, S., Spraul, M., Lachenmeir, D., Rinke, P. & Duarte, I., 2008, Proceedings of the 7th Joint Meeting of GA, AFERP, ASP, PSE & SIF, Athens, Greece, August 3-8, 2008. Vol. 74. p. 900

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

Fruit juices
Screening
Nuclear magnetic resonance
Beer
Metabolites
21 Citations (Scopus)
Intramolecular Transferases
Isocitrate Lyase
Oxaloacetic Acid
Enzymes
Serine
76 Citations (Scopus)

Influence of cellular ER alpha/ER beta ratio on the ER alpha-agonist induced proliferation of human T47D breast cancer cells

Sotoca Covaleda, A. M., van den Berg, H., Vervoort, J. J. M., van der Saag, P., Strom, A., Gustafsson, J. A., Rietjens, I. M. C. M. & Murk, A. J., 2008, In : Toxicological sciences. 105, 2, p. 303-311

Research output: Contribution to journalArticleAcademicpeer-review

Estrogen Receptor beta
Estrogen Receptor alpha
Estrogen Receptors
Estrogens
Cells
55 Citations (Scopus)
Open Access
Metabolomics
Liquid chromatography
Lycopersicon esculentum
Metabolites
Liquid Chromatography
70 Citations (Scopus)

Phytoestrogen-mediated inhibition of proliferation of the human T47D breast cancer cells depends on the ER/ER ratio

Sotoca Covaleda, A. M., Ratman, D., van der Saag, P., Ström, A., Gustafsson, J. A. & Vervoort, J. J. M., 2008, In : Journal of Steroid Biochemistry and Molecular Biology. 112, 4-5, p. 171-178

Research output: Contribution to journalArticleAcademicpeer-review

Phytoestrogens
Cell proliferation
Cells
Cell Proliferation
Breast Neoplasms

Plant-fungus interactions with emphasis on the pathosystem Cladosporium fulvum-tomato

de Wit, P. J. G. M., van t Klooster, J. W., van Esse, H. P., Bolton, M., Gabriëls, S. H. E. J., Vervoort, J. J. M., Boeren, S., Stulemeijer, I. J. E., Joosten, M. H. A. J., Thomma, B. P. H. J. & Stergiopoulos, I., 2008, Book of Abstracts Advances in Molecular Plant-Microbe Interactions, Taipei, Taiwan, 18-19 March 2008. p. 9-10

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

23 Citations (Scopus)

QSAR models for predicting in vivo aquatic toxicity of chlorinated alkanes to fish

Zvinavashe, E., van den Berg, J. H. J., Soffers, A. E. M. F., Vervoort, J. J. M., Freidig, A., Murk, A. J. & Rietjens, I. M. C. M., 2008, In : Chemical Research in Toxicology. 21, 3, p. 739-745

Research output: Contribution to journalArticleAcademicpeer-review

Alkanes
Fish
Toxicity
Fishes
Computer Simulation
30 Citations (Scopus)

Role of Catechin Quinones in the Induction of EpRE-Mediated Gene Expression

Muzolf-Panek, M., Gliszczynska-Swiglo, A., de Haan, L. H. J., Aarts, J. M. M. J. G., Szymusiak, H., Vervoort, J. J. M., Tyrakowska, B. & Rietjens, I. M. C. M., 2008, In : Chemical Research in Toxicology. 21, 12, p. 2352-2360

Research output: Contribution to journalArticleAcademicpeer-review

Quinones
Catechin
Gene expression
Pyrogallol
Gene Expression
167 Citations (Scopus)

The Cladosporium fulvum virulence protein Avr2 inhibits host proteases required for basal defense

van Esse, H. P., van t Klooster, J. W., Bolton, M. D., Yadeta, K. A., van Baarlen, P., Boeren, S., Vervoort, J. J. M., de Wit, P. J. G. M. & Thomma, B. P. H. J., 2008, In : The Plant Cell. 20, 7, p. 1948-1963

Research output: Contribution to journalArticleAcademicpeer-review

Passalora fulva
Cladosporium
Lycopersicon esculentum
Virulence
Peptide Hydrolases

The SERK1 protein complexes

Karlova, R. B., 2008, S.l.: S.n.. 142 p.

Research output: Thesisinternal PhD, WUAcademic

Open Access
brassinosteroids
proteins
cells
receptors
phytosterols
2007

3DM from data to medicine

Joosten, H. J., 2007, [S.l.]: S.n.. 108 p.

Research output: Thesisinternal PhD, WUAcademic

Open Access
Medicine
Proteins
Oxalates
Fungi
oxaloacetase

Development of a computational chemistry-based QSAR approach that sets priorities in toxicity testing of selected groups of EINECS list chemicals.

Zvinavashe, E., Murk, A. J., Vervoort, J. J. M., Soffers, A. E. M. F., Freidig, A. & Rietjens, I. M. C. M., 2007, In : NCA-Newsletter. 22, p. 3-5

Research output: Contribution to journalComment/Letter to the editorAcademic

Open Access
43 Citations (Scopus)

Human glutathione S-transferase-mediated glutathione conjugation of curcumin and efflux of these conjugates in Caco-2 cells

Usta, M., Wortelboer, H. M., Vervoort, J. J. M., Boersma, M. G., Rietjens, I. M. C. M., van Bladeren, P. J. & Cnubben, N. H. P., 2007, In : Chemical Research in Toxicology. 20, 12, p. 1895-1902

Research output: Contribution to journalArticleAcademicpeer-review

Curcumin
Caco-2 Cells
Glutathione Transferase
Glutathione
Liver
170 Citations (Scopus)

Identification of the major constituents of Hypericum perforatum by LC/SPE/NMR and/or LC/MS.

Tatsis, E. C., Boeren, J. A., Exarchou, V., Troganis, A. N., Vervoort, J. J. M. & Gerothanassis, I. P., 2007, In : Phytochemistry. 68, 3, p. 383-393

Research output: Contribution to journalArticleAcademicpeer-review

hyperforin
Phloroglucinol
Hypericum
Hypericum perforatum
Nuclear magnetic resonance
227 Citations (Scopus)

Metabolomics technologies and metabolite identification

Moco, S. I. A., Bino, R. J., de Vos, C. H. & Vervoort, J. J. M., 2007, In : TrAC : Trends in Analytical Chemistry. 26, 9, p. 855-866

Research output: Contribution to journalArticleAcademicpeer-review

Metabolites
Biological systems
Mass spectrometry
Nuclear magnetic resonance
Liquid chromatography
Open Access
Liquid chromatography
Metabolites
Fruits
Mass spectrometry
Nuclear magnetic resonance
30 Citations (Scopus)

Molecular determinants of xenobiotic metabolism: QM/MM simulation of the conversion of 1-chloro-2,4-dinitrobenzene catalyzed by M1-1 glutathione S-transferase.

Bowman, A. L., Ridder, L., Rietjens, I. M. C. M., Vervoort, J. J. M. & Mulholland, A. J., 2007, In : Biochemistry. 46, 21, p. 6353-6363

Research output: Contribution to journalArticleAcademicpeer-review

Dinitrochlorobenzene
Xenobiotics
Glutathione Transferase
Metabolism
Molecular Dynamics Simulation

PAMPs, effectors, their targets and host responses in the pathosystem Cladosporium fulvum-tomato

de Wit, P. J. G. M., Stergiopoulos, I., van t Klooster, J. W., van Esse, P., Fradin, E. F., Ellendorff, U., Gabriëls, S., Stulemeijer, I., Vossen, J. H., Bolton, M. D., Borrás-Hidalgo, O., Tameling, W. I. L., Abd-El-Haliem, A. M., van den Berg-Velthuis, G., Vervoort, J. J. M., Boeren, J. A., Joosten, M. H. A. J. & Thomma, B. P. H. J., 2007, Book of Abstracts XIII International Congress on Molecular Plant-Microbe Interactions, Sorrento, Italy, 21-27 July 2007. p. 43

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

16 Citations (Scopus)

Syringa oblata Lindl var. alba as a source of oleuropein and related compounds

Nenadis, N., Vervoort, J. J. M., Boeren, J. A. & Tsimidou, M. Z., 2007, In : Journal of the Science of Food and Agriculture. 87, 1, p. 160-166

Research output: Contribution to journalArticleAcademicpeer-review

Syringa
oleuropein
extracts
High Pressure Liquid Chromatography
verbascoside

The Cladosporium fulvum effector protein Avr2 is a novel cysteine protease inhibitor

van t Klooster, J. W., van der Kamp, M. W., Vervoort, J. J. M., Beekwilder, J., Thomma, B. P. H. J., Joosten, M. H. A. J. & de Wit, P. J. G. M., 2007, Book of Abstracts XIII International Congress on Molecular Plant-Microbe Interactions, Sorrento, Italy, 21-27 July 2007. p. 271

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

Open Access
135 Citations (Scopus)

Tissue specialization at the metabolite level is perceived during the development of tomota fruit.

Moco, S. I. A., Capanoglu, E., Tikunov, Y. M., Bino, R. J., Boyacioglu, D., Hall, R. D., Vervoort, J. J. M. & de Vos, C. H., 2007, In : Journal of Experimental Botany. 58, 15-16, p. 4131-4146

Research output: Contribution to journalArticleAcademicpeer-review

Lycopersicon esculentum
fruiting
Fruit
metabolites
tomatoes