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Research Output 1983 2019

2019
Open Access
Maerua
glucobrassicin
Gene expression
Cytotoxicity
Fruits
1 Citation (Scopus)

Hazard assessment of Maerua subcordata (Gilg) DeWolf. for selected endpoints using a battery of in vitro tests

Gebrelibanos Hiben, M., Kamelia, L., de Haan, L., Spenkelink, B., Wesseling, S., Vervoort, J. & Rietjens, I. M. C. M., 15 Sep 2019, In : Journal of Ethnopharmacology. 241, 111978.

Research output: Contribution to journalArticleAcademicpeer-review

Aryl Hydrocarbon Receptors
Fruit
Zebrafish
Isothiocyanates
Traditional Medicine

Human Milk Short-Chain Fatty Acid Composition is Associated with Adiposity Outcomes in Infants

Prentice, P. M., Schoemaker, M. H., Vervoort, J., Hettinga, K., Lambers, T. T., van Tol, E. A. F., Acerini, C. L., Olga, L., Petry, C. J., Hughes, I. A., Koulman, A., Ong, K. K. & Dunger, D. B., May 2019, In : The Journal of Nutrition. 149, 5, p. 716-722

Research output: Contribution to journalArticleAcademicpeer-review

Volatile Fatty Acids
Adiposity
Human Milk
formic acid
Skinfold Thickness

Induction of EpRE-mediated gene expression by a series of mediterranean botanicals and their constituents

Papadi, G., Wesseling, S., Troganis, A. N., Vervoort, J. & Rietjens, I. M. C. M., 10 Aug 2019, In : Journal of Ethnopharmacology. 240, 13 p., 111940.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Frangula
Rhamnus
Gene Expression
Liquid Chromatography
Mass Spectrometry

Short communication: Changes under low ambient temperatures in the milk lipodome and metabolome of mid-lactation cows after dehorning as a calf

Baars, T., Jahreis, G., Lorkowski, S., Rohrer, C., Vervoort, J. & Hettinga, K., Mar 2019, In : Journal of Dairy Science. 102, 3, p. 2698-2702

Research output: Contribution to journalArticleAcademicpeer-review

dehorning
metabolome
Metabolome
Lactation
ambient temperature
2018
diacylglycerol acyltransferase
dietary fat
Holstein
lactation
metabolites
1 Citation (Scopus)

Identifying anti-HSV compounds from unrelated plants using NMR and LC–MS metabolomic analysis

Prinsloo, G. & Vervoort, J., Oct 2018, In : Metabolomics. 14, 10, 134.

Research output: Contribution to journalArticleAcademicpeer-review

Metabolomics
Simplexvirus
Viruses
Chlorogenic Acid
Nuclear magnetic resonance
2 Citations (Scopus)
Open Access
Physical Chemistry
Physical chemistry
Nanoparticles
Polystyrenes
Adhesion
9 Citations (Scopus)

Integrative analysis of gut microbiota composition, host colonic gene expression and intraluminal metabolites in aging C57BL/6J mice

van der Lugt, B., Rusli, F., Lute, C., Lamprakis, A., Salazar, E., Boekschoten, M. V., Hooiveld, G. J., Müller, M., Vervoort, J., Kersten, S., Belzer, C., Kok, D. E. G. & Steegenga, W. T., 16 May 2018, In : Aging. 10, 5, p. 930-950

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Inbred C57BL Mouse
Gene Expression
Health
Desulfovibrio
Bifidobacterium
4 Citations (Scopus)

Lifelong calorie restriction affects indicators of colonic health in aging C57Bl/6J mice

Kok, D. E. G., Rusli, F., van der Lugt, B., Lute, C., Laghi, L., Salvioli, S., Picone, G., Franceschi, C., Smidt, H., Vervoort, J., Kampman, E., Müller, M. & Steegenga, W. T., 1 Jun 2018, In : Journal of Nutritional Biochemistry. 56, p. 152-164

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Nutrition
Aging of materials
Health
Diet
Metabolites
2 Citations (Scopus)

Milk Metabolomics Data Reveal the Energy Balance of Individual Dairy Cows in Early Lactation

Xu, W., Vervoort, J., Saccenti, E., van Hoeij, R., Kemp, B. & van Knegsel, A., 25 Oct 2018, In : Scientific Reports. 8, 15828.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Metabolomics
Lactation
Milk
Metabolome
Carnitine
4 Citations (Scopus)

Modification of chrysanthemum odour and taste with chrysanthemol synthase induces strong dual resistance against cotton aphids

Li, J., Delatte, T., Vervoort, J., Gao, L., Verstappen, F., Xiong, W., Gan, J., Jongsma, M. A. & Wang, C., Aug 2018, In : Plant Biotechnology Journal. 16, 8, p. 1434-1445

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Chrysanthemum
Aphids
Aphis gossypii
Aphidoidea
odors

Prediction of Metabolic Status of Dairy Cows in Early Lactation Using On-farm Cow Data with Machine Learning Algorithms

Xu, W., Saccenti, E., Vervoort, J. J. M., Kemp, B. & van Knegsel, A. T. M., 5 Feb 2018, Abstract of the WIAS Science Day 2018. p. 22-22

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

3 Citations (Scopus)

Type 2 diabetes-related proteins derived from an in vitro model of inflamed fat tissue

ten Klooster, J. P., Sotiriou, A., Boeren, S., Vaessen, S., Vervoort, J. & Pieters, R., 15 Apr 2018, In : Archives of Biochemistry and Biophysics. 644, p. 81-92

Research output: Contribution to journalArticleAcademicpeer-review

Intra-Abdominal Fat
Macrophages
Medical problems
Type 2 Diabetes Mellitus
Fats

Use of proteomics to detect sex-related differences in effects of toxicants: implications for using proteomics in toxicology

Rietjens, I. M. C. M., Vervoort, J., Maslowska-Górnicz, A., Van den Brink, N. & Beekmann, K., 14 Sep 2018, In : Critical Reviews in Toxicology. 48, 8, p. 666-681

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
Sex Characteristics
Proteomics
Toxicology
Toxic Actions
Biomarkers
2017
9 Citations (Scopus)

Determination and risk assessment of naturally occurring genotoxic and carcinogenic alkenylbenzenes in basil-containing sauce of pesto

Al-Malahmeh, A. J., Al-Ajlouni, A. M., Wesseling, S., Vervoort, J. & Rietjens, I. M. C. M., 2017, In : Toxicology Reports. 4, p. 1-8

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
methyleugenol
Ocimum basilicum
Risk assessment
Risk Management
Risk management
6 Citations (Scopus)

Determination and risk assessment of naturally occurring genotoxic and carcinogenic alkenylbenzenes in nutmeg-based plant food supplements

Al-Malahmeh, A. J., Alajlouni, A., Ning, J., Wesseling, S., Vervoort, J. & Rietjens, I. M. C. M., 2017, In : Journal of Applied Toxicology. 37, 10, p. 1254-1264

Research output: Contribution to journalArticleAcademicpeer-review

Myristica fragrans
Dietary Supplements
Risk assessment
Body Weight
Risk Management
12 Citations (Scopus)

Effect of processing intensity on immunologically active bovine milk serum proteins

Brick, T., Ege, M., Boeren, S., Böck, A., Von Mutius, E., Vervoort, J. & Hettinga, K., 2017, In : Nutrients. 9, 9, p. 1-14 963.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Milk Proteins
whey
blood proteins
Blood Proteins
Milk
9 Citations (Scopus)

Human milk peptides differentiate between the preterm and term infant and across varying lactational stages

Dingess, K. A., de Waard, M., Boeren, S., Vervoort, J., Lambers, T. T., van Goudoever, J. B. & Hettinga, K., 1 Oct 2017, In : Food & Function. 8, 10, p. 3769-3782

Research output: Contribution to journalArticleAcademicpeer-review

Human Milk
breast milk
Premature Infants
peptides
Peptides
5 Citations (Scopus)
Biological Assay
Health
In Vitro Techniques

Milk metabolomics reveals the metabolic profile and energy balance of dairy cows in early lactation

Xu, W., van Knegsel, A. T. M., Kemp, B. & Vervoort, J. J. M., 2017, Abstracts of the 6th BASF Workshop: Health and Nutrition in High-Yielding Dairy Cows.

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

9 Citations (Scopus)

Mixed colonies of Aspergillus niger and Aspergillus oryzae cooperatively degrading wheat bran

Benoit-Gelber, I., Gruntjes, T., Vinck, A., van Veluw, J. G., Wösten, H. A. B., Boeren, S., Vervoort, J. J. M. & de Vries, R. P., 2017, In : Fungal Genetics and Biology. 102, p. 31-37

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Aspergillus oryzae
Aspergillus niger
Dietary Fiber
Enzymes
Fungi

Mode of action based risk assessment of the botanical food-borne alkenylbenzenesapiol and myristicin

Alajlouni, A., 2017, Wageningen: Wageningen University. 212 p.

Research output: Thesisinternal PhD, WUAcademic

Open Access
risk assessment
food
kinetics
tumor
tea
21 Citations (Scopus)

Modulation of the gut microbiota impacts nonalcoholic fatty liver disease: a potential role for bile acids

Janssen, A. W. F., Houben, T., Katiraei, S., Dijk, W., Boutens, L., van der Bolt, N., Wang, Z., Brown, J. M., Hazen, S. L., Mandard, S., Shiri-Sverdlov, R., Kuipers, F., Willems van Dijk, K., Vervoort, J., Stienstra, R., Hooiveld, G. J. E. J. & Kersten, S., 2017, In : Journal of Lipid Research. 58, 7, p. 1399-1416

Research output: Contribution to journalArticleAcademicpeer-review

guar gum
Bile Acids and Salts
Liver
Modulation
Inflammation
13 Citations (Scopus)

Physiologically based kinetic modeling of the bioactivation of myristicin

Al-Malahmeh, A. J., Al-Ajlouni, A., Wesseling, S., Soffers, A. E. M. F., Al-Subeihi, A., Kiwamoto, R., Vervoort, J. & Rietjens, I. M. C. M., 2017, In : Archives of Toxicology. 91, 22 p., 713.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Safrole
Kinetics
Metabolites
Rats
Liver
6 Citations (Scopus)
Anethum graveolens
Petroselinum
dill
parsley
Dietary Supplements
5 Citations (Scopus)

Streptococcus salivarius MS-oral-D6 promotes gingival re-epithelialization in vitro through a secreted serine protease

Fernandez Gutierrez, M., Roosjen, P. P. J., Ultee, E., Agelink, M., Vervoort, J. J. M., Keijser, B., Wells, J. M. & Kleerebezem, M., 2017, In : Scientific Reports. 7, 15 p., 11100.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Re-Epithelialization
Serine Proteases
Bacteria
Oral Health
Wound Healing
7 Citations (Scopus)
Dosimetry
Toxicity
Rats
Risk assessment
No-Observed-Adverse-Effect Level

Use of physiologically based kinetic modelling facilitated read-across in risk assessment of botanical food-borne alkenylbenzenes

Al-Malahmeh, A., 2017, Wageningen: Wageningen University. 237 p.

Research output: Thesisinternal PhD, WUAcademic

Open Access
risk assessment
kinetics
food
modeling
tumor
2016
37 Citations (Scopus)

Breast milk nutrient content and infancy growth

Prentice, P., Ong, K. K., Schoemaker, M. H., van Tol, E. A. F., Vervoort, J., Hughes, I. A., Acerini, C. L. & Dunger, D. B., 2016, In : Acta Paediatrica : International Journal of Paediatrics. 105, p. 641-647

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Human Milk
Food
Growth
Body Mass Index
Fats
13 Citations (Scopus)

Changes over lactation in breast milk serum proteins involved in the maturation of immune and digestive system of the infant

Zhang, L., de Waard, M., Verheijen, H., Boeren, S., Hageman, J. A., van Hooijdonk, T., Vervoort, J., van Goudoever, J. B. & Hettinga, K., 2016, In : Journal of Proteomics. 147, p. 40-47

Research output: Contribution to journalArticleAcademicpeer-review

Digestive system
Digestive System
Milk Proteins
Immune system
Human Milk
3 Citations (Scopus)

Characterization of the transcriptional regulation of the tariJKL locus involved in ribitol-containing wall teichoic acid biosynthesis in Lactobacillus plantarum

Tomita, S., Lee, I. C., van Swam, I. I., Boeren, S., Vervoort, J., Bron, P. A. & Kleerebezem, M., 1 Feb 2016, In : Microbiology. 162, 2, p. 420-432 000229.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Ribitol
Teichoic Acids
Lactobacillus plantarum
Sugar Alcohols
Proteins
5 Citations (Scopus)

In vitro digestibility and fermentability of selected insects for dog foods

Bosch, G., Vervoort, J. J. M. & Hendriks, W. H., 2016, In : Animal Feed Science and Technology. 221, p. 174-184

Research output: Contribution to journalArticleAcademicpeer-review

pet foods
in vitro digestibility
insects
larvae
chitin
7 Citations (Scopus)

Level of Alkenylbenzenes in Parsley and Dill Based Teas and Associated Risk Assessment Using the Margin of Exposure Approach

Alajlouni, A., Al-Malahmeh, A. J., Isnaeni, F. N., Wesseling, S., Vervoort, J. & Rietjens, I. M. C. M., 2016, In : Journal of Agricultural and Food Chemistry. 64, 45, p. 8640-8646

Research output: Contribution to journalArticleAcademicpeer-review

Anethum graveolens
Petroselinum
dill
parsley
Tea

Metabolite profiles in blood and milk for cows with different dry period lengths in early lactation

Xu, W., van Knegsel, A. T. M., de Koning, D. B., van Hoeij, R. J., Kemp, B. & Vervoort, J. J. M., 2016, 16th International Conference on Production Diseases in Farm Animals: Book of abstracts. Wageningen: Wageningen Academic, p. 120-120

Research output: Chapter in Book/Report/Conference proceedingAbstractAcademic

Open Access

Metabolite profiles in blood and milk for cows with different dry period lengths in early lactation

Xu, W., van Knegsel, A. T. M., de Koning, D. B., van Hoeij, R. J., Kemp, B. & Vervoort, J. J. M., 2016.

Research output: Contribution to conferenceAbstractAcademic

8 Citations (Scopus)

Milk metabolome relates enteric methane emission to milk synthesis and energy metabolism pathways

Antunes-Fernandes, E. C., van Gastelen, S., Dijkstra, J., Hettinga, K. A. & Vervoort, J., 2016, In : Journal of Dairy Science. 99, 8, p. 6251-6262

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
milk synthesis
metabolome
Metabolome
Methane
energy metabolism
11 Citations (Scopus)

Mode of action based risk assessment of the botanical food-borne alkenylbenzene apiol from parsley using physiologically based kinetic (PBK) modelling and read-across from safrole

Alajlouni, A. M., Al-Malahmeh, A. J., Kiwamoto, R., Wesseling, S., Soffers, A. E. M. F., Al-Subeihi, A. A. A., Vervoort, J. & Rietjens, I. M. C. M., 1 Mar 2016, In : Food and Chemical Toxicology. 89, p. 138-150

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Safrole
safrole
Petroselinum
parsley
Risk assessment
5 Citations (Scopus)

Network analysis of metabolite GWAS hits: Implication of CPS1 and the urea cycle in weight maintenance

Matone, A., Scott-Boyer, M. P., Carayol, J., Fazelzadeh, P., Lefebvre, G., Valsesia, A., Charon, C., Vervoort, J., Astrup, A., Saris, W. H. M., Morine, M. & Hager, J., 2016, In : PLoS ONE. 11, 3, e150495.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Carbamyl Phosphate
Genome-Wide Association Study
weight control
Electric network analysis
Metabolites

Novel targets for the development of drugs for Type 2 Diabetes Mellitus

Sotiriou, A., 2016, Wageningen: Wageningen University. 137 p.

Research output: Thesisinternal PhD, WUAcademic

Open Access
Resistin
Type 2 Diabetes Mellitus
Pharmaceutical Preparations
Adipocytes
Hypoglycemic Agents
16 Citations (Scopus)

Proteomic study on the stability of proteins in bovine, camel, and caprine milk sera after processing

Zhang, L., Boeren, S., Smits, M., van Hooijdonk, T., Vervoort, J. & Hettinga, K., 2016, In : Food Research International. 82, p. 104-111

Research output: Contribution to journalArticleAcademicpeer-review

camel milk
Pasteurization
Camelus
Protein Stability
Milk Proteins
23 Citations (Scopus)

The muscle metabolome differs between healthy and frail older adults

Fazelzadeh, P., Hangelbroek, R. W. J., Tieland, C. A. B., de Groot, C. P. G. M., Verdijk, L., van Loon, L. J. C., Smilde, A. K., Alves Rolo, R., Vervoort, J. J. M., Müller, M. R., van Duynhoven, J. P. M. & Boekschoten, M. V., 2016, In : Journal of Proteome Research. 15, 2, p. 499-509

Research output: Contribution to journalArticleAcademicpeer-review

Frail Elderly
Metabolome
Muscle
Muscles
Branched Chain Amino Acids
13 Citations (Scopus)

The protein and lipid composition of the membrane of milk fat globules depends on their size

Lu, J., Argov-Argaman, N., Anggrek, J., Boeren, S., van Hooijdonk, T., Vervoort, J. & Hettinga, K. A., 2016, In : Journal of Dairy Science. 99, 6, p. 4726-4738 74498.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
fat globules
protein composition
Membrane Lipids
lipid composition
milk fat

Transcriptional Analysis of serk1 and serk3 coreceptor mutants

van Esse, W., ten Hove, C. A., Guzzonato, F., van Esse, P., Boekschoten, M., Ridder, L., Vervoort, J. & de Vries, S. C., 2016, In : Plant Physiology. 172, 4, p. 2516-2529

Research output: Contribution to journalArticleAcademicpeer-review

Brassinosteroids
brassinosteroids
mutants
Arabidopsis
Secondary Metabolism
6 Citations (Scopus)

Weight loss predictability by plasma metabolic signatures in adults with obesity and morbid obesity of the DiOGenes study

Stroeve, J. H. M., Saccenti, E., Bouwman, J., Dane, A., Strassburg, K., Vervoort, J., Hankemeier, T., Astrup, A., Smilde, A. K., Van Ommen, B. & Saris, W. H. M., 2016, In : Obesity. 24, 2, p. 379-388

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Morbid Obesity
Weight Loss
Obesity
Caloric Restriction
Metabolome
2015
13 Citations (Scopus)

A proteomic perspective on the changes in milk proteins due to high somatic cell count

Zhang, L., Boeren, J. A., van Hooijdonk, A. C. M., Vervoort, J. J. M. & Hettinga, K. A., 2015, In : Journal of Dairy Science. 98, 8, p. 5339-5351

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Milk Proteins
milk proteins
somatic cell count
Proteomics
proteomics

Automated Annotation of Microbial and Human Flavonoid-Derived Metabolites

Mihaleva, V. V., Ünlü, F., Vervoort, J. J. M. & Ridder, L. O., 2015, Metabonomics and Gut Microbiota in Nutrition and Disease. Kochhar, S. & Martin, F. P. (eds.). London, p. 109-124 (Molecular and Integrative Toxicology).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

metabolite
software
feces
urine
nuclear magnetic resonance
32 Citations (Scopus)

Bovine Milk Proteome in the First 9 Days: Protein Interactions in Maturation of the Immune and Digestive System of the Newborn

Zhang, L., Boeren, J. A., Hageman, J. A., van Hooijdonk, A. C. M., Vervoort, J. J. M. & Hettinga, K. A., 2015, In : PLoS ONE. 10, 2, 19 p., e0116710.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Digestive system
Digestive System
Immune system
Proteome
proteome
16 Citations (Scopus)

Difference in the Breast Milk Proteome between Allergic and Non-Allergic Mothers

Hettinga, K. A., Reina, F. M., Boeren, J. A., Zhang, L., Koppelman, G. H., Postma, D. S., Vervoort, J. J. M. & Wijga, A. H., 2015, In : PLoS ONE. 10, 3, 11 p., e0122234.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Human Milk
Proteome
breast milk
proteome
Allergies
33 Citations (Scopus)

Direct comparison of metabolic health effects of the flavonoids quercetin, hesperetin, epicatechin, apigenin and anthocyanins in high-fat-diet-fed mice

Hoek-van den Hil, E. F., van Schothorst, E. M., van der Stelt, I., Swarts, J. J. M., van Vliet, M. A., Amolo, T., Vervoort, J. J. M., Venema, D. P., Hollman, P. C. H., Rietjens, I. M. C. M. & Keijer, J., 2015, In : Genes & Nutrition. 10, 4, 13 p., 23.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Apigenin
Anthocyanins
Catechin
Quercetin
High Fat Diet