If you made any changes in Pure these will be visible here soon.

Research Output 1981 2020

2003

Different modes of major histocompatibility class I and class II evolution in the Lake Tana Barbus species flock

Kruiswijk, C. P., Hermsen, G. J., van Heerwaarden, J., Dixon, B., Savelkoul, H. F. J. & Stet, R. J. M., 2003, 9th International Congress of ISDCI, St. Andrews Scotland; programme & abstracts. Dyrynda, E. A. (ed.). p. 173

Research output: Chapter in Book/Report/Conference proceedingAbstract

48 Citations (Scopus)

Early in vivo cytokine genes expression in chickens after challenge with Salmonella typhimurium lipopolysaccharide and modulation by dietary n-3 polyunsaturated fatty acids

Sijben, J. W. C., Klasing, K. C., Schrama, J. W., Parmentier, H. K., van der Poel, J. J., Savelkoul, H. F. J. & Kaiser, P., 2003, In : Developmental and Comparative Immunology. 27, p. 611-619

Research output: Contribution to journalArticleAcademicpeer-review

Omega-3 Fatty Acids
Salmonella typhimurium
Lipopolysaccharides
Chickens
Cytokines

Evolution and function of CXC chemokines and their receptors in vertebrates

Huising, M. O., Stolte, H. H., Flik, G., Savelkoul, H. F. J. & Verburg-van Kemenade, B. M. L., 2003, 9th International Congress of ISDCI St Andrews, Scotland; Programme & Abstracts. p. 106

Research output: Chapter in Book/Report/Conference proceedingAbstract

Evolution of vertebrate cytokines

Huising, M. O., van Schijndel, J., Kruiswijk, C. P., Joerink, M., Verburg-van Kemenade, B. M. L. & Savelkoul, H. F. J., 2003.

Research output: Contribution to conferenceAbstractAcademic

Functional aspects of tumour necrosis factor proteins in carp (Cyprinus carpio)

Scharsack, J. P., Saeij, J. P. J., Zou, J., Secombes, C. J., Savelkoul, H. F. J., Stet, R. J. M. & Wiegertjes, G. F., 2003, 9th International Congress of ISDCI, St. Andrews Scotland; programme & abstracts. Dyrynida, E. A. (ed.). p. 179

Research output: Chapter in Book/Report/Conference proceedingAbstract

Hoe schoon is schoon?

Savelkoul, H. F. J., 2003, In : Top Santé. p. 70-75 6 p.

Research output: Contribution to journalArticlePopular

Hygienehypothese: allergie door een verstoord regulatornetwerk

Savelkoul, H. F. J., 2003, In : Pulmonair. juni, p. 16-21 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Identification and immuno-modulatory activity of chicken natural antibodies

Lammers, A., Savelkoul, H. F. J. & Parmentier, H. K., 2003, Abstracts of the 15th European Immunology Congress (EFIS 2003). Vol. 87. p. 40

Research output: Chapter in Book/Report/Conference proceedingAbstract

Identification of immuno-regulatory molecules of fish by micro-array technology

Stolte, H. H., Leon, K. M., Kramer, J., Flik, G., Savelkoul, H. F. J. & Verburg-van Kemenade, B. M. L., 2003.

Research output: Contribution to conferenceAbstractAcademic

52 Citations (Scopus)

Immunoactive, medicinal properties of mushroom and herb polysaccharides and their potential use in chicken diets

Guo, F., Savelkoul, H. F. J., Kwakkel, R. P., Williams, B. A. & Verstegen, M. W. A., 2003, In : Worlds Poultry Science Journal. 59, p. 427-440

Research output: Contribution to journalArticleAcademicpeer-review

medicinal properties
mushrooms
herbs
polysaccharides
chickens
62 Citations (Scopus)

Increased efficacy of immersion vaccination in fish with hyperosmotic pretreatment

Huising, M. O., Guichelaar, T., Hoek, C., Verburg-van Kemenade, B. M. L., Flik, G., Savelkoul, H. F. J. & Rombout, J. H. W. M., 2003, In : Vaccine. 21, 27-30, p. 4178-4193 16 p.

Research output: Contribution to journalArticleAcademicpeer-review

Immersion
Fishes
Vaccination
pretreatment
vaccination
11 Citations (Scopus)

Increased serum IL-10/IL-12 ratio in wheezing infants

Koopman, L. P., Savelkoul, H. F. J., van Benten, I. J., Gerritsen, J., Brunekreef, B. & Neijens, H. J., 2003, In : Pediatric Allergy and Immunology. 14, p. 112-119 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Respiratory Sounds
Interleukin-12
Interleukin-10
Serum
Exanthema
17 Citations (Scopus)

Islet transplantation in the discordant tilapia-to-mouse model: a novel application of alginate microencapsulation in the study of xenograft rejection

Dickson, B. C., Yang, H., Savelkoul, H. F. J., Rowden, G., van Rooijen, N. & Wright Jr., J. R., 2003, In : Transplantation. 75, 5, p. 599-606

Research output: Contribution to journalArticleAcademicpeer-review

Tilapia
Islets of Langerhans Transplantation
Drug Compounding
Graft Survival
Heterografts

Is ons voedsel veilig?

Savelkoul, H. F. J., 2003, In : Melange. 3, p. 15 1 p.

Research output: Contribution to journalArticlePopular

Macrophage polarisation in carp (Cyprinus carpio)

Joerink, M., Savelkoul, H. F. J. & Wiegertjes, G. F., 2003, 9th International Congress of ISDCI, St. Andrews Scotland; programme & abstracts. Dyrynda, E. A. (ed.). p. 38

Research output: Chapter in Book/Report/Conference proceedingAbstract

106 Citations (Scopus)

Molecular evolution of CXC chemokines: extant CXC chemokines originate from the CNS

Huising, M. O., Stet, R. J. M., Kruiswijk, C. P., Savelkoul, H. F. J. & Verburg-van Kemenade, B. M. L., 2003, In : Trends in Immunology. 24, 6, p. 306-312

Research output: Contribution to journalArticleAcademicpeer-review

CXC Chemokines
Molecular Evolution
Vertebrates
Immune System
Tetraodontiformes

Molecular evolution of the interleukin-1 family of cytokines: fish have ILI-18 and IL-18 receptors

Verburg-van Kemenade, B. M. L., Huising, M. O. & Savelkoul, H. F. J., 2003, 9th International Congress of ISDCI St Andrews, Scotland; programme & abstracts. p. 87

Research output: Chapter in Book/Report/Conference proceedingAbstract

Natural antibodies in chickens are genetically determined and affect antigen-specific humoral and cellular responses

Savelkoul, H. F. J., van der Poel, J. J. & Parmentier, H. K., 2003, 9th International Congress of ISDCI, St. Andrews Scotland; programme & abstracts. Dyrynda, E. A. (ed.). p. 73

Research output: Chapter in Book/Report/Conference proceedingAbstract

Novel immunoglobulin-like transcripts (nilts): an evolutionary conserved feature of innate immunity

Stet, R. J. M., Hermsen, G. J., Engelsma, M. Y., Jukes, J., van Keulen, B., Verburg-van Kemenade, B. M. L., Shum, B. & Savelkoul, H. F. J., 2003, 9th International Congress of ISDCI, St. Andrews Scotland; programme & abstracts. Dyrynda, E. A. (ed.). p. 51

Research output: Chapter in Book/Report/Conference proceedingAbstract

17 Citations (Scopus)

Polymorphism of major histocompatibility complex class II B genes in different carp lines of the common carp (Cyprinus carpio L.)

Rakus, K. L., Wiegertjes, G. F., Stet, R. J. M., Savelkoul, H. F. J., Pilarczyk, A. & Irnazarow, I., 2003, In : Aquatic Living Resources. 16, p. 432-437 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

major histocompatibility complex
Cyprinus carpio
carp
polymorphism
genetic polymorphism

Response to shields: molecular evolution of CXC chemokines and receptors

Huising, M. O., Stet, R. J. M., Kruiswijk, C. P., Savelkoul, H. F. J. & Verburg-van Kemenade, B. M. L., 2003, In : Trends in Immunology. 24, 7, p. 356-357 2 p.

Research output: Contribution to journalLetterAcademicpeer-review

16 Citations (Scopus)

Soluble E-selectin and soluble ICAM-1 levels as markers of the activity of atopic dermatitis in children

Wolkerstorfer, A., Savelkoul, H. F. J., de Waard van der Spek, F. B., Neijens, H. J., van Meurs, T. & Oranje, A. P., 2003, In : Pediatric Allergy and Immunology. 14, p. 302-306 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

E-Selectin
Intercellular Adhesion Molecule-1
Atopic Dermatitis
Selectins
Therapeutics

The ancestral role of CXC chemokines: CXC chemokines predate the immune system

Huising, M. O., Kruiswijk, C. P., Stet, R. J. M., Savelkoul, H. F. J. & Verburg-van Kemenade, B. M. L., 2003.

Research output: Contribution to conferenceAbstractAcademic

4 Citations (Scopus)

T helper cell polarisation as a measure of the maturation of the immune response

Cameron, S. B., Stolte, H. H., Chow, A. W. & Savelkoul, H. F. J., 2003, In : Mediators of Inflammation. 12, 5, p. 285-292 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Helper-Inducer T-Lymphocytes
Cytokines
T-Lymphocytes
Enzyme-Linked Immunosorbent Assay
Staining and Labeling

The role of nitric oxide in the immune response to 'tryps' in carp, Cyprinus carpio

Forlenza, M., Saeij, J. P. J., Zou, J., Secombes, C. J., Savelkoul, H. F. J., Stet, R. J. M. & Wiegertjes, G. F., 2003, 9th International Congress of ISDCI, St. Andrews Scotland; programme & abstracts. Dyrynda, E. A. (ed.). p. 130

Research output: Chapter in Book/Report/Conference proceedingAbstract

2002
52 Citations (Scopus)

A novel functional class I lineage in zebrafish (Danio rerio), carp (Cyprinus carpio), and large barbus (Barbus intermedius)showing an unusual conservation of the peptide binding domains.

Kruiswijk, C. P., Hermsen, G. J., Westphal, A. H., Savelkoul, H. F. J. & Stet, R. J. M., 2002, In : The Journal of Immunology. 169, p. 1936-1947

Research output: Contribution to journalArticleAcademicpeer-review

Cyprinidae
Carps
MHC Class I Genes
Zebrafish
MHC Class II Genes

Evolution of CXC chemokines in vertebrates

Huising, M. O., Stolte, H. H., Verburg-van Kemenade, B. M. L. & Savelkoul, H. F. J., 2002, Abstracts NVVI Jaarcongres 2003 : NVVI Jaarcongres 2003, Veldhoven, 2003. [S.l.]: S.n., p. np

Research output: Chapter in Book/Report/Conference proceedingAbstract

Identification of carp transferrin cDNA : preliminary identification of polymorphism

Jurecka, P., Irnazarow, I., Pilarczyk, A., Savelkoul, H. F. J. & Wiegertjes, G. F., 2002, Abstracts of the International Scientific Conference about Current Problems of Animal Genetics and their Practical Application, Brno, Czech Republic, 2002.

Research output: Chapter in Book/Report/Conference proceedingAbstract

Immuunregulatie bij de ontwikkeling van allergie op de jonge kinderleeftijd.

Stolte, H. H., Neijens, H. J. & Savelkoul, H. F. J., 2002, In : Nederlands Tijdschrift voor Allergie. 1, p. 18-30

Research output: Contribution to journalArticleAcademicpeer-review

30 Citations (Scopus)

Inhibition of septic shock in mice by an oligopeptide from the beta-chain of human chorionic gonadotrophin hormone

Khan, N. A., Khan, A., Savelkoul, H. F. J. & Benner, R., 2002, In : Human Immunology. 63, p. 1-7

Research output: Contribution to journalArticleAcademicpeer-review

Chorionic Gonadotropin, beta Subunit, Human
Oligopeptides
Septic Shock
Chorionic Gonadotropin
Hormones

Innate immune responses to parasites in carp, Cyprinus carpio L

Forlenza, M., Savelkoul, H. F. J. & Wiegertjes, G. F., 2002, Abstracts of the Jaarcongres NVVI, Veldhoven, 2002..

Research output: Chapter in Book/Report/Conference proceedingAbstract

914 Citations (Scopus)

In vitro generation of interleukin-10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper 1 (Th1)- and Th2-inducing cytokines

Barrat, F. J., Cua, D. J., Boonstra, P. A., Richards, D. F., Crain, C., Savelkoul, H. F. J., de Waal-Malefyt, R., Coffman, R. L., Hawrylowicz, C. M. & O'Garra, A., 2002, In : Journal of Experimental Medicine. 195, p. 603-616.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Polymorphism of MHC class II B genes in different lines of common carp (Cyprinus carpio L.)

Rakus, K., Wiegertjes, G. F., Stet, R. J. M., Savelkoul, H. F. J., Pilarczyk, A. & Irnazarow, I., 2002, Abstracts of the International Scientific Conference about Current Problems of Animal Genetics and their Practical Application, Brno, Czech Republic, 2002.

Research output: Chapter in Book/Report/Conference proceedingAbstract

275 Citations (Scopus)

Prospective study on the relationship between infections and multiple sclerosis exacerbations

Buljevac, D., Flach, H. Z., Hop, W. C., Hijdra, D., Laman, J. D., Savelkoul, H. F. J., van der Meche, F. G., van Doorn, P. A. & Hintzen, R. Q., 2002, In : Brain. 125, p. 952-960.

Research output: Contribution to journalArticleAcademicpeer-review

2001
732 Citations (Scopus)

1alpha,25-dihydroxyvitamin D3 has a direct effect on naive CD4+ T cells to enhance the development of Th2 cells

Boonstra, A., Barrat, F. J., Crain, C., Heath, V. L., Savelkoul, H. F. J. & O'Garra, A., 2001, In : The Journal of Immunology. 167, p. 4974-4980

Research output: Contribution to journalArticleAcademicpeer-review

Th2 Cells
Calcitriol
T-Lymphocytes
Interleukin-4
MafF Transcription Factor

A novel functional class I lineage in three cyprinid species: Barbus, carp and zebrafish

Kruiswijk, C. P., Hermsen, G. T., Savelkoul, H. F. J. & Stet, R. J. M., 2001, Abstracts Nederlandse Vereniging voor Immunologie : NVVI Conference, Noordwijkerhout, december 2001. - [S.l.] : [s.n.], 2001.

Research output: Chapter in Book/Report/Conference proceedingAbstract

A role for interleukin-1beta in neuroendocrine-immune interactions in carp, Cyprinus carpio L.

Engelsma, M. Y., Stet, R. J. M., Savelkoul, H. F. J. & Verburg-van Kemenade, B. M. L., 2001, Abstracts Najaarsvergadering NVVI : Najaarvergadering Nederlandse Vereniging voor Immunologie, Noordwijkerhout, december 2001. - [S.l.] : [s.n.], 2001.

Research output: Chapter in Book/Report/Conference proceedingAbstract

25 Citations (Scopus)

Clinico-immunological heterogeneity in Comel-Netherton syndrome

van Gysel, D., Koning, H., Baert, M. R., Savelkoul, H. F. J., Neijens, H. J. & Oranje, A. P., 2001, In : Dermatology. 202, p. 99-107.

Research output: Contribution to journalArticleAcademicpeer-review

Netherton Syndrome
Immunoglobulin E
Atopic Dermatitis
Skin Abnormalities
Cytokines
22 Citations (Scopus)

Differential UVB-induced modulation of cytokine production in XPA, XPC, and CSB repair-deficient mice

Boonstra, A. P., van Oudenaren, A., Baert, M. R. M., van Steeg, H., Leenen, P. J., van der Horst, G. T. J., Hoeijmakers, J. H. J., Savelkoul, H. F. J. & Garssen, J., 2001, In : Journal of Investigative Dermatology. 117, p. 141-146.

Research output: Contribution to journalArticleAcademicpeer-review

Repair
DNA Repair
Modulation
Cytokines
Nucleotides
76 Citations (Scopus)

Enforced expression of GATA-3 in transgenic mice inhibits Th1 differentiation and induces the formation of a T1/ST2-expressing Th2-committed T Cell compartment in vivo

Nawijn, M. C., Dingjan, G. M., Ferreira, R., Lambrecht, B. N., Karis, A., Grosveld, F., Savelkoul, H. F. J. & Hendriks, R. W., 2001, In : The Journal of Immunology. 167, 2, p. 724-732

Research output: Contribution to journalArticleAcademicpeer-review

Transgenic Mice
T-Lymphocytes
Th2 Cells
Cytokines
Locus Control Region

Enhancement of vaccine uptake and immune response in carp after immersion vaccination

Huising, M. O., Guichelaar, T., Hoek, C., Taverne, A., Rombout, J. H. W. M., Flik, G., Verburg-van Kemenade, B. M. L. & Savelkoul, H. F. J., 2001, Najaarsvergadering NVVI : Najaarsvergadering Nederlandse Vereniging voor Immunologie, Noordwijkerhout, december 2001. p. 52

Research output: Chapter in Book/Report/Conference proceedingAbstract

Influences of osmotic shock on efficacy of vaccine uptake and immune response in common carp (Cyprinus carpio L.)

Huising, M. O., Guichelaar, T., Savelkoul, H. F. J., Rombout, J. H. W. M., Flik, G. & Verburg-van Kemenade, B. M. L., 2001, 5th Nordic Symposium on Fish Immunology : 5th Nordic Symposium on Fish Immunology, Sundvolden, Norway, June 2001. p. 51

Research output: Chapter in Book/Report/Conference proceedingAbstract

Influences of osmotic shock on the efficacy of vaccine uptake and immune response in common carp (Cyprinus carpio L.)

Guichelaar, T., Hoek, C., Taverne-Thiele, A., Savelkoul, H. F. J., Rombout, J. H. W. M., Flik, G., Verburg-van Kemenade, B. M. L. & Huising, M. O., 2001, Abstracts 8th Benelux congress of zoology : 8th Benelux congress of zoology, Nijmegen, November 2001.

Research output: Chapter in Book/Report/Conference proceedingAbstract

44 Citations (Scopus)

Inhibition of diabetes in NOD mice by human pregnancy factor

Khan, N. A., Khan, A., Savelkoul, H. F. J. & Benner, R., 2001, In : Human Immunology. 62, p. 1315-1323.

Research output: Contribution to journalArticleAcademicpeer-review

Inbred NOD Mouse
Chorionic Gonadotropin
Pregnancy
Hormones
Hypoglycemic Agents

Natural cytotoxicity receptors: an evolutionary conserved feature of innate immunity

Stet, R. J. M., Jukes, J., Siebenga, J., Verburg-van Kemenade, B. M. L., Savelkoul, H. F. J., Shum, B., Parham, P. & Engelsma, M. Y., 2001, Abstracts najaarsvergadering NVVI : Najaarsvergadering Nederlandse Vereniging voor Immunologie, Noordwijkerhout, december 2001.

Research output: Chapter in Book/Report/Conference proceedingAbstract

Neuro-endocrine immune interactions during stress: a role for cortisol and interleukin-1

Verburg-van Kemenade, B. M. L., Engelsma, M. Y., Huising, M. O., van Muiswinkel, W. B., Savelkoul, H. F. J., Kwang, J. & Flik, G., 2001, Abstracts 8th Benelux congress of zoology : 8th Benelux congress of zoology, Nijmegen, November 2001.

Research output: Chapter in Book/Report/Conference proceedingAbstract

Neuro-endocrine immune interactions during stress: hormones beyond the scope of the endocrine system

Huising, M. O., van Schooten, C., Schreurs, K., Engelsma, M. Y., van den Burg, E., Savelkoul, H. F. J., Flik, G. & Verburg-van Kemenade, B. M. L., 2001, Abstracts 8th Benelux Congress of Zoology : 8th Benelux Congress of Zoology, Nijmegen, November 2001.

Research output: Chapter in Book/Report/Conference proceedingAbstract

28 Citations (Scopus)

Regulation of helper T cell responses to staphylococcal superantigens

Cameron, S. B., Nawijn, M. C., Savelkoul, H. F. J. & Chow, A. W., 2001, In : European Cytokine Network. 12, p. 210-222.

Research output: Contribution to journalArticleAcademicpeer-review

Superantigens
T-cells
Helper-Inducer T-Lymphocytes
Interleukin-4
Cytokines
132 Citations (Scopus)

Selective development of a strong Th2 cytokine profile in high-risk children who develop atopy: risk factors and regulatory role of IFN-? IL-4 and IL-10

van der Velden, V. H. J., Laan, M. P., Baert, M. R. M., de Waal-Malefyt, R., Neijens, H. J. & Savelkoul, H. F. J., 2001, In : Clinical and Experimental Allergy. 31, p. 997-1006.

Research output: Contribution to journalArticleAcademicpeer-review

Interleukin-4
Interleukin-10
Allergens
Cytokines
Parturition