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Research Output 1981 2020

2006
90 Citations (Scopus)

Head kidney-derived macrophages of common carp (Cyprinus carpio L.) show plasticity and functional polarization upon differential stimulation

Joerink, M., Ribeiro, C. M. S., Stet, R. J. M., Hermsen, G. J., Savelkoul, H. F. J. & Wiegertjes, G. F., 2006, In : The Journal of Immunology. 177, 1, p. 61-69 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Head Kidney
Carps
Macrophages
Myeloid Cells
Fishes

Molecular cloning and expression of a Toll receptor in the giant tiger shrimp Peneaus monodon

Arts, J. A. J., Cornelissen, F., Cijsouw, T., Hermsen, G. J., Savelkoul, H. F. J. & Stet, R. J. M., 2006, Abstracts 10th ISDCI Congress. Charleston, USA, p. 67 1 p.

Research output: Chapter in Book/Report/Conference proceedingAbstract

Polarization of carp macrophages : differential receptor expression

Ribeiro, C. M. S., Joerink, M., Savelkoul, H. F. J. & Wiegertjes, G. F., 2006, Abstracts 10th ISCDI Congress. Charleston, USA, p. 205 1 p.

Research output: Chapter in Book/Report/Conference proceedingAbstract

100 Citations (Scopus)

Prediction of mortality risk in the elderly, clinical research study

Störk, S., Feelders, R. A., van den Beld, A. W., Steyerberg, E. W., Savelkoul, H. F. J., Lamberts, S. W. J., Grobbee, D. E. & Bots, M. L., 2006, In : The American Journal of Medicine. 119, 6, p. 519-525 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Mortality
Interleukin-6
Research
C-Reactive Protein
Clinical Studies

Probiotica en Prebiotica (hoofdstuk 27)

Savelkoul, H. F. J., Duiverman, E. J. & Kneepkens, C. M. F., 2006, Werkboek Kinderallergologie. Brand, P. L. P., Kneepkens, C. M. F., van der Laag, J. & Rikkers-Mutsaerts, E. R. V. M. (eds.). Amsterdam, p. 192-196 210 p. (Werkboeken Kindergeneeskunde).

Research output: Chapter in Book/Report/Conference proceedingChapter

57 Citations (Scopus)

The presence of multiple and differentially regulated interleukin-12p40 genes in bony fishes signifies an expansion of the vertebrate heterodimeric cytokine family

Huising, M. O., van Schijndel, J., Kruiswijk, C. P., Nabuurs, S. B., Savelkoul, H. F. J., Flik, G. & Verburg-van Kemenade, B. M. L., 2006, In : Molecular Immunology. 43, 10, p. 1519-1533 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Carps
Interleukins
Interleukin-12 Subunit p40
Vertebrates
Fishes

Trypanosomes in carp (Cyprinus carpio L.) as a model for host-parasite immunity in fish

Wiegertjes, G. F., Forlenza, M., Ribeiro, C. M. S., Joerink, M. & Savelkoul, H. F. J., 2006, Abstracts 10th ISDCI Congress. Charleston, USA, p. 249 1 p.

Research output: Chapter in Book/Report/Conference proceedingAbstract

Type-1 cytokines in teleost fish: evolutionary conservation in relation to their functions

Verburg-van Kemenade, B. M. L., Flik, G., Savelkoul, H. F. J. & Huising, M. O., 2006, Abstracts 10th ISDCI Congress 2006. Charleston, USA, p. 205 1 p.

Research output: Chapter in Book/Report/Conference proceedingAbstract

2005

Allergie : een probleem voor mens en dier

Savelkoul, H. F. J., 2005, In : Animal Sciences Krant. p. 2

Research output: Contribution to journalArticlePopular

Allergie : ook voor allergie geldt: voorkomen is beter dan genezen

Savelkoul, H. F. J., 2005, In : Patient Care. 32, 10, p. 56-58 3 p.

Research output: Contribution to journalArticleProfessional

239 Citations (Scopus)

Antiinflammatory and immunomodulating properties of fungal metabolites

Lull Noguera, C., Wichers, H. J. & Savelkoul, H. F. J., 2005, In : Mediators of Inflammation. 2005, 2, p. 63-80

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Agaricales
Anti-Inflammatory Agents
Disease Resistance
Interleukins
Therapeutic Uses

Carp (Cyprinus carpio L.) macrophage polarization in resonse to parasites

Joerink, M., Savelkoul, H. F. J. & Wiegertjes, G. F., 2005.

Research output: Contribution to conferenceAbstractAcademic

De darm, zijn flora en het brein

Savelkoul, H. F. J., 2005, In : Folia Orthica. 2005, 2, p. 6-9

Research output: Contribution to journalArticleProfessional

Future developments in allergy prevention : a matter of integrating medical, natural and social sciences

Gilissen, L. J. W. J., Wichers, H. J., Savelkoul, H. F. J. & Beers, G., 2005, Allergy Matters : new approaches to allergy prevention and management. Dr. Gilissen, L. J. E. J., Prof.dr. Wichers, H. J., Prof.dr.ir. Savelkoul, H. F. J. & Bogers, J. R. (eds.). p. 3-10 205 p. (Wageningen UR Frontis Series; no. 10).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Open Access

Genetically determined differences in levels of natural antibodies in carp (Cyprinus carpio L.)

Kachamakova, N., Wiegertjes, G. F., Savelkoul, H. F. J., Pilarczyk, A. & Irnazarow, I., 2005.

Research output: Contribution to conferenceAbstractAcademic

Genetic differences in disease resistance : results of challenges with Trypanoplasma borreli in six common carp (Cyprinus carpio L.) lines

Jurecka, P. M., Rakus, K. L., Onara, D. F., Kachamakova, N., Forlenza, M., Wiegertjes, G. F., Savelkoul, H. F. J., Pilarczyk, A. & Irnazarow, I., 2005.

Research output: Contribution to conferenceAbstractAcademic

32 Citations (Scopus)

Gut flora in health and disease : potential role of probiotics

Heselmans, M., Reid, G., Akkermans, L. M. A., Savelkoul, H. F. J., Timmerman, H. & Rombouts, F. M., 2005, In : Current Issues in Intestinal Microbiology. 6, 1, p. 1-8 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Probiotics
Health
Education
Immune System Diseases
Gastroenterology

Induction and regulation of allergen-specific IgE

Jeurink, P. V. & Savelkoul, H. F. J., 2005, Allergy Matters : new approaches to allergy prevention and management. Dr. Gilissen, L. J. E. J., Prof.dr. Wichers, H. J., Prof.dr.ir. Savelkoul, H. F. J. & Bogers, R. J. (eds.). p. 13-27 205 p. (Wageningen UR Frontis Series; no. 10).

Research output: Chapter in Book/Report/Conference proceedingChapter

Open Access
Allergens
Immunoglobulin E
Hypersensitivity
Cell Differentiation
B-Lymphocyte Subsets

Kruisreacties bij voedselallergie

Jeurink, P. V. & Savelkoul, H. F. J., 2005, In : NVOX Tijdschrift voor Natuurwetenschap op School. 30, 1, p. 3-5

Research output: Contribution to journalArticlePopular

21 Citations (Scopus)

Major histocompatibility genes in the Lake Tana African large barb species flock: evidence for complete partitioning of class II B, but nog class I, genes among different species

Kruiswijk, C. P., Hermsen, G. J., van Heerwaarden, J., Dixon, B., Savelkoul, H. F. J. & Stet, R. J. M., 2005, In : Immunogenetics. 56, 12, p. 894-908 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

MHC Class I Genes
Histocompatibility
Lakes
Exons
Genes

Maturation of the immune response

Savelkoul, H. F. J., Cameron, S. B. & Chow, A. W., 2005, Encyclopedic Reference of Immunotoxicology. Werner, H. W. (ed.). Heidelberg: Springer, p. np

Research output: Chapter in Book/Report/Conference proceedingChapter

21 Citations (Scopus)

Multidose streptozotocin induction of diabetes in BALB/c mice induces a dominant oxidative macrophage and a conversion of TH1 to TH2 phenotypes during disease progression

Sun, N., Yang, G., Zhao, H., Savelkoul, H. F. J. & An, L., 2005, In : Mediators of Inflammation. 2005, 4, p. 202-209 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Experimental Diabetes Mellitus
Disease Progression
Type 1 Diabetes Mellitus
Macrophages
Phenotype
46 Citations (Scopus)

Multiple and highly divergent IL-11 genes in teleost fish

Huising, M. O., Kruiswijk, C. P., van Schijndel, J., Savelkoul, H. F. J., Flik, G. & Verburg-van Kemenade, B. M. L., 2005, In : Immunogenetics. 57, 6, p. 432-443 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Interleukin-11
Fishes
Genes
Carps
Oncorhynchus mykiss
41 Citations (Scopus)

Novel immunoglobulin-like transcripts in teleost fish encode polymorphic receptors with cytoplasmic ITAM or ITIM an a new structural Ig domain similar to the natural cytotoxicity receptor NKp44

Stet, R. J. M., Hermsen, G. J., Westphal, A. H., Jukes, J., Engelsma, M. Y., Verburg-van Kemenade, B. M. L., Dortmans, J. C. F. M., Aveiro, J. & Savelkoul, H. F. J., 2005, In : Immunogenetics. 57, 1-2, p. 77-89 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Natural Cytotoxicity Triggering Receptor 2
Cytoplasmic and Nuclear Receptors
Tyrosine
Immunoglobulins
Fishes

Purification and characterization of natural Dau c 1 from Daucus carota Narbonne and Api g 1 from Apium graveolens

Bollen, M. A., Wichers, H. J., Helsper, J. P. F. G., Savelkoul, H. F. J. & van Boekel, M. A. J. S., 2005.

Research output: Contribution to conferencePosterProfessional

2004
38 Citations (Scopus)

Adoptive transfer of natural antibodies to non-immunized chickens affects subsequent antigen-specific humoral and cellular immune responses

Lammers, A., Klomp, M. E. V., Nieuwland, M. G. B., Savelkoul, H. F. J. & Parmentier, H. K., 2004, In : Developmental and Comparative Immunology. 28, 1, p. 51-60

Research output: Contribution to journalArticleAcademicpeer-review

Adoptive Transfer
Humoral Immunity
Cellular Immunity
Chickens
Antigens

Allergie: overgevoeligheid voor voedsel genetisch aangepakt

Savelkoul, H. F. J. & Gilissen, L. J. W. J., 2004, In : Resource: weekblad voor Wageningen UR. 13, p. 12-14

Research output: Contribution to journalArticlePopular

38 Citations (Scopus)

Analysis of genomic and expressed major histocompatibility class Ia and class II genes in a hexaploid Lake Tana African 'large' barb individual (Barbus intermedius)

Kruiswijk, C. P., Hermsen, G. J., Fujiki, K., Dixon, B., Savelkoul, H. F. J. & Stet, R. J. M., 2004, In : Immunogenetics. 55, 11, p. 770-781 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Cyprinidae
MHC Class II Genes
Histocompatibility
Lakes
Major Histocompatibility Complex

Autisme is meer dan een hersenziekte

Savelkoul, H. F. J., 2004, In : Weleda Artsen Forum. 24, p. 1-3 3 p.

Research output: Contribution to journalArticlePopular

Open Access

De darmflora van een autist

Savelkoul, H. F. J., 2004, In : Limburgs Dagblad.

Research output: Contribution to journalArticlePopular

2 Citations (Scopus)

Dierziektebeleid spot met Darwin

van der Weijden, W. J., Savelkoul, H. F. J., Hin, K. J. & de Wilt, J., 2004, In : Tijdschrift voor Diergeneeskunde. 129, 12, p. 418-420 3 p.

Research output: Contribution to journalEditorialAcademicpeer-review

Open Access
22 Citations (Scopus)
Open Access
lipopolysaccharides
erythrocytes
chickens
sheep
antibodies
105 Citations (Scopus)

Different levels of natural antibodies in chickens divergently selected for specific antibody responses

Parmentier, H. K., Lammers, A., Hoekman, J. J., de Vries Reilingh, G., Zaanen, I. T. A. & Savelkoul, H. F. J., 2004, In : Developmental and Comparative Immunology. 28, 1, p. 39-49

Research output: Contribution to journalArticleAcademicpeer-review

Antibody Formation
Chickens
Antibodies
Antigens
Immunoglobulins

Hatsjie!

Savelkoul, H. F. J., 2004, In : Intermediair. 26, p. 41-43 3 p.

Research output: Contribution to journalArticlePopular

Identification of immuno-regulatory molecules of fish by micro-array technology

Stolte, H. H., Leon, K. M., Kramer, J., Flik, G., Savelkoul, H. F. J. & Verburg-van Kemenade, B. M. L., 2004, Abstracts of PhD retreat/WIAS symposium May 2004. Nijmegen, p. 41

Research output: Chapter in Book/Report/Conference proceedingAbstract

Kruisreacties bij voedselallergie

Jeurink, P. V. & Savelkoul, H. F. J., 2004, In : Voeding Nu. 6, 6, p. 23-26

Research output: Contribution to journalArticleProfessional

Open Access

Preventie van een allergie: een gezondheidsissue

Savelkoul, H. F. J., 2004, Syllabus symposium - Nutricia, Duik in de wereld van allergiepreventie, recente voedingskundige inzichten en toekomstige ontwikkelingen, Harderwijk 14-10-2004. Harderwijk, p. 4-8

Research output: Chapter in Book/Report/Conference proceedingConference paper

29 Citations (Scopus)

Serum haemolytic complement activities in 11 different MHC (B) typed chicken lines

Parmentier, H. K., Baelmans, R., Savelkoul, H. F. J., Dorny, P., Demey, F. & Berkvens, D., 2004, In : Veterinary Immunology and Immunopathology. 100, 1-2, p. 25-32

Research output: Contribution to journalArticleAcademicpeer-review

Haplotypes
Chickens
haplotypes
Complement System Proteins
complement

Stress regulated corticosteroid receptor expression in common carp (Cyprinus carpio L.)

Stolte, H. H., Leon, K. M., Savelkoul, H. F. J., Flik, G. & Verburg-van Kemenade, B. M. L., 2004, Abstracts 5th International Symposium on Fish Endocrinology, Castellon, Spanje, 5-9 September 2004. Castellon, Spanje, p. 164

Research output: Chapter in Book/Report/Conference proceedingAbstract

Open Access

Strijd tegen allergie

Savelkoul, H. F. J., 2004, In : Algemeen Dagblad. 1 p.

Research output: Contribution to journalArticlePopular

44 Citations (Scopus)
allergens
Allergens
epitopes
peanuts
Epitopes
104 Citations (Scopus)

The molecular evolution of the interleukin-1 family of cytokines; IL-18 in teleost fish

Huising, M. O., Stet, R. J. M., Savelkoul, H. F. J. & Verburg-van Kemenade, B. M. L., 2004, In : Developmental and Comparative Immunology. 28, 5, p. 395-413 19 p.

Research output: Contribution to journalArticleAcademicpeer-review

Interleukin-18
Molecular Evolution
Interleukin-1
Fishes
Cytokines

Voedselallergie, relatie tussen klachten en voedsel alleen aantoonbaar via provocatietest

Savelkoul, H. F. J., 2004, In : Medisch Contact. 59, 52, p. 2080-2083

Research output: Contribution to journalArticleProfessional

Open Access
2003
24 Citations (Scopus)

A Gly15Arg mutation in the Interleukin-10 gene reduces secretion of Interleukin-10 in Crohn disease

van der Linde, K., Boor, P. P. C., Sandkuijl, L. A., Meijssen, M. A. C., Savelkoul, H. F. J., Wilson, J. H. P. & Rooij, F. W. M., 2003, In : Scandinavian Journal of Gastroenterology. 38, 6, p. 611-617

Research output: Contribution to journalArticleAcademicpeer-review

Crohn Disease
Interleukin-10
Mutation
Genes
HL-60 Cells

Allelic variation of MHC class II B in genetically different lines of common carp

Rakus, K. L., Stet, R. J. M., Irnazarow, I., Pilarczyk, A., Savelkoul, H. F. J. & Wiegertjes, G. F., 2003, 9th International Congress of ISDCI, St. Andrews Scotland. Dyrynda, E. A. (ed.). p. 175

Research output: Chapter in Book/Report/Conference proceedingAbstract

Allergie en de hygienehypothese: de rol van een verstoord regulatoir netwerk

Eek, A. & Savelkoul, H. F. J., 2003, In : Foliolum. 3, p. 7-13

Research output: Contribution to journalArticlePopular

Classically versus alternatively activated macrophages in fish

Joerink, M., Savelkoul, H. F. J. & Wiegertjes, G. F., 2003.

Research output: Contribution to conferenceAbstractAcademic

94 Citations (Scopus)

CXC chemokines and leukocyte chemotaxis in common carp (Cyprinus carpio L.)

Huising, M. O., Stolte, H. H., Flik, G., Savelkoul, H. F. J. & Verburg-van Kemenade, B. M. L., 2003, In : Developmental and Comparative Immunology. 27, 10, p. 875-888 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Leukocyte Chemotaxis
CXC Chemokines
Carps
Chemotaxis
Head Kidney

Detection of polymorphism of MHC class II B genes in different carp lines

Rakus, K. L., Stet, R. J. M., Savelkoul, H. F. J., Irnazarow, I., Pilarczyk, A. & Wiegertjes, G. F., 2003.

Research output: Contribution to conferenceAbstractAcademic