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Research Output 1981 2020

1992

Interleukines from transfected cell lines

Savelkoul, H. F. J., 1992, Course manual "Cell culture for clinic and pharmaceutical industry". Utrecht: University Hospital, p. 1-6

Research output: Chapter in Book/Report/Conference proceedingChapter

1991

Cytokines from transfected cells

Savelkoul, H. F. J., 1991, Course Book International Biotechnology: Cell culture for clinic and pharmaceutical industry. Utrecht: S.n., p. 1-3

Research output: Chapter in Book/Report/Conference proceedingChapter

Evaluation of the purity of synthetic oligonucleotides for PCR amplification by ion exchange FPLC

Savelkoul, H. F. J. & van der Plas, D., 1991, In : Science Tools: the L K B instrument journal. 35:, p. 1-3.

Research output: Contribution to journalArticleProfessional

30 Citations (Scopus)

IL-4 can correct defective IgE production in SJA/9 mice

Savelkoul, H. F. J., Seymour, B. W. P., Sullivan, L. & Coffman, R. L., 1991, In : The Journal of Immunology. 146, 6, p. 1801-1805

Research output: Contribution to journalArticleAcademicpeer-review

Interleukin-4
Immunoglobulin E
Helminths
T-Lymphocytes
Parasitic Diseases

Isolation of monoclonal antibodies from in vitro cultures of human B cell lines employing an automated three-column FLPC system

Savelkoul, H. F. J. & van der Linde-Preesman, A. A., 1991, Proceedings of the fourth FPLC symposium. Woerden: Pharmacia, p. 73-82

Research output: Chapter in Book/Report/Conference proceedingConference paper

Purity evaluation of synthetic oligonucleotides for PCR amplification by ion exchange FPLC

Savelkoul, H. F. J., van der Plas, D. & van Helden-Meeuwsen, C. G., 1991, Proceedings of the fourth FPLC symposium. Woerden: Pharmacia, p. 12-22

Research output: Chapter in Book/Report/Conference proceedingConference paper

Rapid purification of mouse IgE antibodies by multi-column liquid chromatography

Savelkoul, H. F. J., Pathak, S. S. & van der Linde-Preesman, A. A., 1991, Proceedings of the fourth FPLC symposium. Woerden: Pharmacia, p. 83-93

Research output: Chapter in Book/Report/Conference proceedingConference paper

14 Citations (Scopus)

Regulation of IgE production in mice

Benner, R. & Savelkoul, H. F. J., 1991, In : European Respiratory Journal. 4, 13, p. 97s-104s.

Research output: Contribution to journalArticleAcademicpeer-review

Immunoglobulin E
Lymphokines
Helper-Inducer T-Lymphocytes
Interleukin-4
Interferon-gamma
2 Citations (Scopus)

Suppression of graft-versus-host reactivity by a single host-specific blood transfusion to prospective donors of hemopoietic cells

Knulst, A. C., Bril-Bazuin, C., Savelkoul, H. F. J. & Benner, R., 1991, In : Transplantation. 52, 3, p. 534-539

Research output: Contribution to journalArticleAcademicpeer-review

Blood Transfusion
Transplants
Spleen
Clone Cells
T-Lymphocytes
1990

Immunologie

Savelkoul, H. F. J., 1990, In : O'dokter. 9, Issue, p. 12-14

Research output: Contribution to journalArticleProfessional

Regulation of the production of IgE

Benner, R. & Savelkoul, H. F. J., 1990, Post Graduate Course Pollinosis 1990 Erasmus University, Rotterdam. Rotterdam: Erasmus University, p. 15-18

Research output: Chapter in Book/Report/Conference proceedingChapter

1989
34 Citations (Scopus)

Cytokine regulation of immunoglobulin isotype switching and expression

Coffman, R. L., Savelkoul, H. F. J. & Lebman, D. A., 1989, In : Seminars in Immunology. 1, 1, p. 55-63.

Research output: Contribution to journalArticleAcademic

Modulation of total IgE levels in serum of normal and athymic nude BALB/c mice by cells and exogenous antigenic stimulation

Savelkoul, H. F. J., van den Akker, T. W., Soeting, P. W. C., van Oudenaren, A. & Benner, R., 1989, In : International Archives of Allergy and Immunology. 89, p. 113-119.

Research output: Contribution to journalArticleAcademicpeer-review

Immunoglobulin E
Serum
T-Lymphocytes
Thymectomy
Nude Mice
2 Citations (Scopus)

Terasaki-ELISA for murine IgE-anibodies III. determination of concentration and functional affinity by sequential equilibrium binding analysis

Pathak, S. S., Vos, Q. & Savelkoul, H. F. J., 1989, In : Journal of Immunological Methods. 123, 1, p. 71-81

Research output: Contribution to journalArticleAcademicpeer-review

Immunoglobulin E
Enzyme-Linked Immunosorbent Assay
Antibody Affinity
Antibodies
Dialysis
4 Citations (Scopus)

Terasaki-ELISA for murine IgE-antibodies.I.Quality of the detecting antibody: production and specificity testing of antisera specific for IgE

Savelkoul, H. F. J., Soeting, P. W. C., Radl, J. & van der Linde-Preesman, A. A., 1989, In : Journal of Immunological Methods. 116, 2, p. 265-275

Research output: Contribution to journalArticleAcademicpeer-review

Antibody Specificity
Immunoglobulin E
Antibody Formation
Immune Sera
Enzyme-Linked Immunosorbent Assay
7 Citations (Scopus)

Terasaki-ELISA for murine IgE antibodies.II.Quantitation of absolute concentration of antigen-specific and total IgE

Savelkoul, H. F. J., Soeting, P. W. C., de Josselin de Jong, J. E. & Pathak, S. S., 1989, In : Journal of Immunological Methods. 116, 2, p. 277-285

Research output: Contribution to journalArticleAcademicpeer-review

Immunoglobulin E
Enzyme-Linked Immunosorbent Assay
Antigens
Antibodies
Galactosidases
1988

An alternative method for immunoblotting on Phast System

van der Linde-Preesman, A. A. & Savelkoul, H. F. J., 1988, Pharmacia Separations. [S.l.]: S.n., p. 1-3

Research output: Chapter in Book/Report/Conference proceedingChapter

Frequency analysis of functional Ig Ce gene expression in the presence and absence of interleukin 4 in lipopolysaccharide-reactive murine B cells from high and low IgE responder strains

Savelkoul, H. F. J., Termeulen, J., Coffman, R. L. & van der Linde-Preesman, A. A., 1988, In : European journal of immunology. 18, p. 1209-1215.

Research output: Contribution to journalArticleAcademicpeer-review

Frequency analysis of functional immunoglobulin CE gene expression in LPS reactive murine B cells

Savelkoul, H. F. J., Linssen, P. C. L. M., Termeulen, J., van der Linde-Preesman, A. A. & Benner, R., 1988, Lymphocyte activation and differentiation.. Mani, J. C. & Dornand, J. (eds.). p. 585-589

Research output: Chapter in Book/Report/Conference proceedingChapter

Generation and measurement of antibodies

Savelkoul, H. F. J., Pathak, S. S., Sabbele, N. R. & Benner, R., 1988, Handbook of Experimental Pharmacology. Vol 85. Bray, M. A. & Morley, J. (eds.). p. 141-185

Research output: Chapter in Book/Report/Conference proceedingChapter

25 Citations (Scopus)

Increase of precursor frequency and clonal size of murine IgE-secreting cells by IL-4

Savelkoul, H. F. J., Lebman, D. A., Benner, R. & Coffman, R. L., 1988, In : The Journal of Immunology. 141, 3, p. 749-755

Research output: Contribution to journalArticleAcademicpeer-review

Interleukin-4
Immunoglobulin E
Clone Cells
Immunoglobulin M
Feeder Cells
4 Citations (Scopus)

Rapid procedure for coupling of protein antigens to red cells to be used in plaque assays by prewashing in chromium chloride

Savelkoul, H. F. J., Greeve, A. A. M., Rijkers, G. T., Marwitz, P. A. & Benner, R., 1988, In : Journal of Immunological Methods. 111, 1, p. 31-37

Research output: Contribution to journalArticleAcademicpeer-review

Staphylococcal Protein A
Antigens
Proteins
gamma-Globulins
Hybridomas
625 Citations (Scopus)

The role of helper T cell products in mouse B cell differentiation and isotype regulation

Coffman, R. L., Seymour, B. W. P., Lebman, D. A., Hiraki, D. D., Christiansen, J. A., Shrader, B., Cherwinski, H. M., Savelkoul, H. F. J., Finkelman, F. D., Bond, M. W. & Mosmann, T. R., 1988, In : Immunological reviews. 102, 1, p. 5-28

Research output: Contribution to journalArticleAcademicpeer-review

1987

Isolation of monoclonal antibodies from in vitro cultures of human B cell lines employing an automated three-column FPLC system

Savelkoul, H. F. J. & van der Linde-Preesman, A. A., 1987, Proceedings second FPLC symposium. Woerden: Pharmacia Nederland, p. 73-82

Research output: Chapter in Book/Report/Conference proceedingConference paper

Occurrence of damaged heavy chains during purification of murine IgE antibodies by fast protein liquid chromatography (FPLC) and their effect on the determination of concentration and affinity in ELISA

Savelkoul, H. F. J., Pathak, S. S. & van der Linde-Preesman, A. A., 1987, Unknown. p. 375-382 (Protides of the biological fluids; no. 35).

Research output: Chapter in Book/Report/Conference proceedingChapter

Rapid purification of mouse IgE antibodies by multi column liquid chromatography

Savelkoul, H. F. J., Pathak, S. S. & van der Linde Preesman, A. A., 1987, In: Proceedings second FPLC symposium. Woerden: Pharmacia Nederland, p. 83-93

Research output: Chapter in Book/Report/Conference proceedingConference paper

1985

Isolation, characterization and quantitation of murine IgE

Savelkoul, H. F. J., Greeve, A. A. M., Soeting, P. W. C., Benner, R. & Radl, J., 1985, Unknown. p. 611-614. (Protides of the biological fluids; no. 33).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Quantitation of murine IgE in an automatic ELISA system

Savelkoul, H. F. J., Soeting, P. W. C., Benner, R. & Radl, J., 1985, In : Advances in Experimental Medicine and Biology. 186, p. 757-765

Research output: Contribution to journalArticleAcademicpeer-review

1983

Short term immunosuppressive effects of Cis-diaminedichloroplatinum (II) (DDP) in mice

Nikkels, P. G. J., Bril, H., Savelkoul, H. F. J., van Oudenaren, A. & Ploemacher, R. E., 1983, Modern Trends in Clinical Immunosuppression.. Weimar, W., Marquet, R. L., Bijnen, A. B. & Ploeg, R. J. (eds.). Rotterdam.: Dept.Renal Transplantation, p. 167-174

Research output: Chapter in Book/Report/Conference proceedingChapter

1982

Factors, receptors, and their ligands: studies with H-2 restricted helper hybridoma clones

Lonai, P., Arman, E., Savelkoul, H. F. J., Friedman, V., Puri, J. & Hammerling, G., 1982, Isolation, characterization, and utilization of T lymphocyte clones.. Fathman, C. G. & Fitch, F. W. (eds.). New York: Academic Press, p. 109-117

Research output: Chapter in Book/Report/Conference proceedingChapter

1981
11 Citations (Scopus)

Two separate genes regulate self-Ia and carrier recognition in H-2-restricted helper factors secreted by hybridoma cells

Lonai, P., Savelkoul, H. F. J., Puri, J. & Hammerling, G., 1981, In : Journal of Experimental Medicine. 154, 6, p. 1910-1921

Research output: Contribution to journalArticleAcademicpeer-review

TCF Transcription Factors
Hybridomas
Sepharose
Lymphoma
T-Lymphocytes