Hetty Busink-van den Broeck

dr.

    1989 …2020

    Research output per year

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    Research Output

    2020

    CRISPR/Cas9 Gene Editing of Gluten in Wheat to Reduce Gluten Content and Exposure—Reviewing Methods to Screen for Coeliac Safety

    Jouanin, A. A., Gilissen, L. J. W. J., Schaart, J. G., Leigh, F. J., Cockram, J., Wallington, E. J., Boyd, L. A., van den Broeck, H. C., van der Meer, I. M., America, A. H. P., Visser, R. G. F. & Smulders, M. J. M., 24 Apr 2020, In : Frontiers in Nutrition. 7, 51.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
    2019

    Impact of Cereal Seed Sprouting on Its Nutritional and Technological Properties: A Critical Review

    Lemmens, E., Moroni, A. V., Pagand, J., Heirbaut, P., Ritala, A., Karlen, Y., Kim-Anne, L., van den Broeck, H. C., Brouns, F. J. P. H., De Brier, N. & Delcour, J. A., 2019, In : Comprehensive Reviews in Food Science and Food Safety. 18, 1, p. 305-328

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
    12 Citations (Scopus)
    2018

    Breeding for healthier wheat

    Gilissen, L. J. W. J. & van den Broeck, H. C., 1 Jul 2018, In : Cereal Foods World. 63, 4, p. 132-136

    Research output: Contribution to journalArticleAcademicpeer-review

    2 Citations (Scopus)

    Food processing and breeding strategies for coeliac-safe and healthy wheat products

    Jouanin, A., Gilissen, L. J. W. J., Boyd, L. A., Cockram, J., Leigh, F. J., Wallington, E. J., van den Broeck, H. C., van der Meer, I. M., Schaart, J. G., Visser, R. G. F. & Smulders, R., Aug 2018, In : Food Research International. 110, p. 11-21

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
    19 Citations (Scopus)

    Oats in healthy gluten-free and regular diets: A perspective

    Smulders, M. J. M., van de Wiel, C. C. M., van den Broeck, H. C., van der Meer, I. M., Israel-Hoevelaken, T. P. M., Timmer, R. D., van Dinter, B. J., Braun, S. & Gilissen, L. J. W. J., Aug 2018, In : Food Research International. 110, p. 3-10

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
    13 Citations (Scopus)
    2016

    Wheat and gluten intolerance

    Busink-van den Broeck, H., Gilissen, L. J. W. J. & Brouns, F., 2016, ICC. 43 p.

    Research output: Book/ReportReportPopular

    2015

    Hoe gevoelig tarwe en gluten liggen

    Gilissen, L. J. W. J. (Guest ed.) & van den Broeck, H. C. (Guest ed.), 2015, In : Voeding Nu. 2015, 7/8, p. 12-14

    Research output: Contribution to journalArticlePopular

    31 Citations (Scopus)

    Profiling of Nutritional and Health-Related Compounds in Oat Varieties

    van den Broeck, H. C., Londono Cardona, D. M., Timmer, R. D., Smulders, M. J. M., Gilissen, L. J. W. J. & van der Meer, I. M., 2015, In : Foods. 5, 2, 11 p., nr 2 Communication.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access

    Quantification of Celiac Disease Gluten Epitopes

    Degg, B. & Busink-van den Broeck, H. C., 2015, In : The Column : the interactive e-publication for the global separation science industry. 11, 11, p. 6

    Research output: Contribution to journalComment/Letter to the editorAcademic

    Open Access
    2014

    Development of wheat varieties with reduced contents of celiac-immunogenic epitopes through conventional and GM strategies

    Smulders, M. J. M., Jouanin, A. A., Schaart, J. G., Visser, R. G. F., Cockram, J., Leigh, F., Wallington, E., Boyd, L. A., van den Broeck, H. C., van der Meer, I. M. & Gilissen, L. J. W. J., 2014, Proceedings of the 28th meeting of the Working Group on Prolamin Analysis and Toxicity. Koehler, P. (ed.). Nantes, France: WGPAT, p. 47-56

    Research output: Chapter in Book/Report/Conference proceedingConference paper

    Open Access

    Glutenvrij ? Pils onde de loep

    Sleutels, I., van der Meer, I. M. & van den Broeck, H. C., 2014, In : Voedingsmiddelentechnologie. 7, p. 10-11

    Research output: Contribution to journalArticlePopular

    Open Access
    2013
    33 Citations (Scopus)

    Quantitation of coeliac toxicity in wheat using genomics and proteomics

    Gilissen, L. J. W. J., Salentijn, E. M. J., van den Broeck, H. C., Cordewener, J. H. G., America, T. H. P., Schaart, J. G., van der Meer, I. M. & Smulders, M. J. M., 2013, Proceedings of the 27th meeting of the working group on prolamin analysis and toxicity. Koehler, P. (ed.). p. 45-51

    Research output: Chapter in Book/Report/Conference proceedingConference paper

    Open Access
    2012

    Food-related strategies towards reduction of gluten intolerance and gluten sensitivity

    Gilissen, L. J. W. J., van den Broeck, H. C., Londono, D. M., Salentijn, E. M. J., Koning, F., van der Meer, I. M. & Smulders, M. J. M., 2012, Proceedings of the 25th Meeting Working Group on Prolamin Analysis and Toxicity (PWG), Felbach, Germany, September 29 - October 2, 2012. Koehler, P. (ed.). p. 29-35

    Research output: Chapter in Book/Report/Conference proceedingConference paper

    Open Access
    2011
    Open Access
    2 Citations (Scopus)
    20 Citations (Scopus)
    2010

    A universal approach to eliminate antigenic properties of alpha-gliadin peptides in celiac disease

    Mitea, C., Salentijn, E. M. J., van Veelen, P., Goryunova-Svetlana, V., van der Meer, I. M., van den Broeck, H. C., Mujico, J. R., Monserrat, V., Gilissen, L. J. W. J., Drijfhout, J. W., Dekking, L. & Smulders, M. J. M., 2010, In : PLoS ONE. 5, 12 p., e15637.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
    52 Citations (Scopus)

    In search of tetraploid wheat accessions reduced in celiac disease-related gluten epitopes

    van den Broeck, H. C., Hongbing, C., Lacaze, X., Dusautoir, J. C., Gilissen, L. J. W. J., Smulders, J. M. & van der Meer, I. M., 2010, In : Molecular BioSystems. 6, 11, p. 2206-2213

    Research output: Contribution to journalArticleAcademicpeer-review

    38 Citations (Scopus)
    Open Access
    103 Citations (Scopus)

    The quest for celiac-safe wheat

    van den Broeck, H. C., 2010, [S.l.: S.n.. 162 p.

    Research output: Thesisinternal PhD, WU

    Open Access

    Reducing celiac disease related gluten proteins in wheat

    Busink, H. C., 2009, In : Separation Science Food Reports. 2009, may, p. 4

    Research output: Contribution to journalArticleProfessional

    Removing celiac disease-related gluten proteins from bread wheat while retaining technological roperties: a study with Chinese Spring deletion Lines

    van den Broeck, H. C., van Herpen, T. W. J. M., Schuit, C. & Salentijn, E. M. J., 2009, In : BMC Plant Biology. 9, 41.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
    78 Citations (Scopus)
    Open Access
    47 Citations (Scopus)
    2008

    Differential expression of genes involved in C1 metabolism and lignin biosynthesis in wooden core and bast tissues of fibre hemp (Cannabis sativa L.).

    van den Broeck, H. C., Maliepaard, C. A., Ebskamp, M. J. M., Toonen, M. A. J. & Koops, A. J., 2008, In : Plant Science. 174, 2, p. 205-220

    Research output: Contribution to journalArticleAcademicpeer-review

    32 Citations (Scopus)
    8 Citations (Scopus)

    Visualising wheat gluten proteins : staining profile depends on the method used

    van den Broeck, H. C., 2008, In : Bioforum Europe. 2008, 9, p. 18-20

    Research output: Contribution to journalArticleProfessional

    Open Access
    2006

    Pathway engineering for healthy phytochemicals leading to the production of novel flavonoids in tomato fruit

    Schijlen, E. G. W. M., de Vos, C. H., Jonker, H. H., van den Broeck, H. C., Molthoff, J. W., van Tunen, A. J., Martens, S. & Bovy, A. G., 2006, In : Plant Biotechnology Journal. 4, 4, p. 433-444

    Research output: Contribution to journalArticleAcademicpeer-review

    116 Citations (Scopus)
    2005

    Integrated statistical analysis of cDNA microarray and NIR spectroscopic data applied to a hemp dataset

    Reijmers, T. H., Maliepaard, C. A., van den Broeck, H. C., Kessler, R. W., Toonen, M. A. J. & van der Voet, H., 2005, In : Journal of Bioinformatics and Computational Biology. 3, 4, p. 891-913

    Research output: Contribution to journalArticleAcademicpeer-review

    4 Citations (Scopus)
    2004

    Identification of differentially expressed genes in fiber hemp (Cannabis sativa L.)

    van den Broeck, H. C., Koops, A. J. & Toonen, M. A. J., 2004, Book of abstracts of the Xth Cell Wall Meeting, Sorrento, Italy. p. 95-95

    Research output: Chapter in Book/Report/Conference proceedingAbstract

    Predicting the chemical composition of fibre and core fraction of hemp (Cannabis sativa L.)

    Toonen, M. A. J., Maliepaard, C. A., Reijmers, T. H., van der Voet, H., Mastebroek, H. D., van den Broeck, H. C., Ebskamp, M. J. M., Kessler, W. & Kessler, R. W., 2004, In : Euphytica. 140, 1-2, p. 39-45

    Research output: Contribution to journalArticleAcademicpeer-review

    21 Citations (Scopus)
    2003

    Applied genomics: an innovative tool to improve quality in chains: Predicting mealiness in apples - a case study

    van Wordragen, M., Balk, P. A., Hall, R. D., Nijenhuis-de Vries, M. A., van den Broeck, H. C., Vorst, O. F. J. & Poelman, A. A. M., 2003, In : Acta Horticulturae. 604, 1, p. 387-394

    Research output: Contribution to journalArticleAcademicpeer-review

    3 Citations (Scopus)

    Response of selected antioxidants and pigments in tissues of Rosa hybrida and Fuchsia hybrida to supplemental UV-A exposure

    Helsper, J. P. F. G., de Vos, C. H., Maas, F. M., Jonker, H. H., van den Broeck, H. C., Jordi, W., Pot, C. S., Keizer, L. C. P. & Schapendonk, A. H. C. M., 2003, In : Physiologia Plantarum. 117, 2, p. 171-178

    Research output: Contribution to journalArticleAcademicpeer-review

    57 Citations (Scopus)
    2002

    Novel Insight into Vascular, Stress and Auxin Dependent and Independent Gene Expression Programs in Strawberry, a Non-Climacteric Fruit

    Aharoni, A., Keizer, L. C. P., van den Broeck, H. C., Bois, G., Smit, P. & de Vos, R. C. H., 2002, In : Plant Physiology. 129, p. 1019-1031

    Research output: Contribution to journalArticleAcademicpeer-review

    152 Citations (Scopus)
    2001

    Purification and characterization of two different a-L-Rhamnosidases, RhaA and RhaB, from Aspergillus aculeatus

    Manzanares, P., Broeck, H. C., de Graaff, L. H. & Visser, J., 2001, In : Applied and Environmental Microbiology. 67, p. 2230-2234

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
    84 Citations (Scopus)
    1999

    Differential expression of three alpha-galactosidase genes and a single beta-galactosidase gene from Aspergillus niger

    de Vries, R. P., van den Broeck, H. C., Dekkers, E., Manzanares, P., de Graaff, L. H. & Visser, J., 1999, In : Applied and Environmental Microbiology. 65, p. 2453-2460

    Research output: Contribution to journalArticleAcademicpeer-review

    92 Citations (Scopus)
    1998

    Cloning and biochemical characterisation of Aspergillus niger hexokinase: the enzyme is strongly inhibited by physiological concentrations of the trehalose-6-phosphate.

    Panneman, H., Ruijter, G. J. G., van den Broeck, H. C. & Visser, J., 1998, In : European Journal of Biochemistry. 258, p. 223-232

    Research output: Contribution to journalArticleAcademicpeer-review

    47 Citations (Scopus)
    1997

    A novel Y-xylosidase, nucleotide sequence encoding it and use thereof

    de Graaff, L. H., van Peij, N. N. M. E., van den Broeck, H. C. & Visser, J., 9 Jan 1997, Patent No. WO9700964, Priority date 23 Jun 1995

    Research output: PatentOther research output

    Open Access
    1996

    Characterisation of the Aspergillus nidulans frA1 mutant: hexose phosphorylation and apparent lack of involvement of hexokinase in glucose repression.

    Ruijter, G. J. G., Panneman, H., van den Broeck, H. C., Bennett, J. M. & Visser, J., 1996, In : FEMS Microbiology Letters. 139, p. 223-228

    Research output: Contribution to journalArticleAcademicpeer-review

    27 Citations (Scopus)

    Cloning and biochemical characterisation of an Aspergillus niger glucokinase. Evidence for the presence of a separate glucokinase and hexokinase enzymes.

    Panneman, H., Ruijter, G. J. G., van den Broeck, H. C., Driever, E. T. M. & Visser, J., 1996, In : European Journal of Biochemistry. 240, p. 518-525

    Research output: Contribution to journalArticleAcademicpeer-review

    30 Citations (Scopus)
    1994

    Regulation of the xylanase-encoding xlnA gene of Aspergillus tubigensis.

    de Graaff, L. H., van den Broeck, H. C., van Ooijen, A. J. J. & Visser, J., 1994, In : Molecular Microbiology. 12, p. 479-490

    Research output: Contribution to journalArticleAcademicpeer-review

    105 Citations (Scopus)
    1993

    Induction of glucose oxidase, catalase and lactonase in Asperillus niger.

    Witteveen, C. F. B., van der Vondervoort, P. J. I., van den Broeck, H. C., van Engelenburg, F. A. C., de Graaff, L. H., Hillebrand, M. H. B. C., Schaap, P. J. & Visser, J., 1993, In : Current Genetics. 24, p. 408-416

    Research output: Contribution to journalArticleAcademicpeer-review

    50 Citations (Scopus)
    1992

    Characterization of the Aspergillus niger pel B gene; structure and regulation of expression.

    Kusters-van Someren, M. A., Flipphi, M. J. A., van den Broeck, H. C., Kester, H., Hinnen, A. & Visser, J., 1992, In : Molecular and General Genetics. 234, p. 113-120

    Research output: Contribution to journalArticleAcademicpeer-review

    61 Citations (Scopus)

    Cloning and expression of xylanase genes from fungal origin.

    van den Broeck, H. C., de Graaff, L. H., Hille, J. D. R., van Ooyen, A. J. J., Visser, J. & Harder, A., 1992, Patent No. EP0463706, Priority date 24 Jul 1991

    Research output: PatentOther research output

    Open Access

    Cloning and use of acetyl xylan esterase from fungal origin.

    de Graaff, L. H., Visser, J., van den Broeck, H. C., Strozyk, F., Kormelink, F. J. M. & Boonman, J. C. P., 1992, Patent No. EP0507369, Priority date 18 Mar 1991

    Research output: PatentOther research output

    Open Access

    Isolation and characterization of the Aspergillus niger pyruvate kinase gene.

    de Graaff, L. H., van den Broeck, H. C. & Visser, J., 1992, In : Current Genetics. 22, p. 21-27

    Research output: Contribution to journalArticleAcademicpeer-review

    41 Citations (Scopus)

    Structure and regulation of an Aspergillus xylanase gene.

    de Graaff, L. H., van den Broeck, H. C., van Ooyen, A. J. J. & Visser, J., 1992, Xylans and xylanases, J. Visser et al. (eds.). Progress in Biotechnology vol. 7. Elsevier, Amsterdam. p. 235-246

    Research output: Chapter in Book/Report/Conference proceedingConference paper