20032020

Research output per year

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Research Output

2020

Accelerated discovery of functional variation in pigs

Derks, M. F. L., Megens, H. J. W. C., Bosse, M., Lopes, M. S., Harlizius, B. & Groenen, M., 14 Feb 2020, Wias Annual Conference 2020: Frontiers in Animal Sciences. WIAS, p. 38-38

Research output: Chapter in Book/Report/Conference proceedingAbstract

Open Access

Coding and non-coding changes drive the repeated evolution of the placenta in live-bearing fish

van Kruistum, H., Nijland, R., Reznick, D. N., Groenen, M., Pollux, B. J. A. & Megens, H. J. W. C., 14 Feb 2020, Wias Annual Conference 2020: Frontiers in Animal Sciences. WIAS, p. 41-41

Research output: Chapter in Book/Report/Conference proceedingAbstract

Open Access

Genome-Wide Association Analysis of adaptation to oxygen variations in Nile Tilapia (Oreochromis niloticus)

Yu, X., Megens, H. J. W. C., Mengistu, S. & Groenen, M., 14 Feb 2020, Wias Annual Conference 2020: Frontiers in Animal Sciences. WIAS, p. 45-45

Research output: Chapter in Book/Report/Conference proceedingAbstract

Open Access

Mixed ancestry from wild and domestic lineages contributes to the rapid expansion of invasive feral swine

Smyser, T. J., Tabak, M. A., Slootmaker, C., Robeson, M. S., Miller, R. S., Bosse, M., Megens, H. J., Groenen, M. A. M., Paiva, S. R., de Faria, D. A., Blackburn, H. D., Schmit, B. S. & Piaggio, A. J., 26 Feb 2020, In : Molecular Ecology. 29, 6

Research output: Contribution to journalArticleAcademicpeer-review

PCADD: SNV prioritisation in Sus scrofa

Groß, C., Derks, M., Megens, H. J., Bosse, M., Groenen, M. A. M., Reinders, M. & De Ridder, D., 7 Feb 2020, In : Genetics Selection Evolution. 52, 1, 4.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The chromosome-scale genome assembly of Visayan warty pig provides insight into porcine evolutionary history

Liu, L., Megens, H. J. W. C., Crooijmans, R. P. M. A., Groenen, M. & Madsen, O., 14 Feb 2020, WIAS Annual Conference 2020: Frontiers in Animal Sciences. WIAS, p. 25-25

Research output: Chapter in Book/Report/Conference proceedingAbstract

Open Access

The genomes of the livebearing fish species Poeciliopsis retropinna and Poeciliopsis turrubarensis reflect their different reproductive strategies

van Kruistum, H., Guernsey, M. W., Baker, J. C., Kloet, S. L., Groenen, M. A. M., Pollux, B. J. A. & Megens, H. J. W. C., May 2020, In : Molecular Biology and Evolution. 37, 5, p. 1376-1386 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access
2019

Ancient pigs reveal a near-complete genomic turnover following their introduction to Europe

Frantz, L. A. F., Haile, J., Lin, A. T., Scheu, A., Geörg, C., Benecke, N., Alexander, M., Linderholm, A., Mullin, V. E., Daly, K. G., Battista, V. M., Price, M., Gron, K. J., Alexandri, P., Arbogast, R. M., Arbuckle, B., Bǎlǎşescu, A., Barnett, R., Bartosiewicz, L., Baryshnikov, G. & 80 others, Bonsall, C., Borić, D., Boroneanţ, A., Bulatović, J., Çakirlar, C., Carretero, J. M., Chapman, J., Church, M., Crooijmans, R., De Cupere, B., Detry, C., Dimitrijevic, V., Dumitraşcu, V., Du Plessis, L., Edwards, C. J., Erek, C. M., Erim-Özdoǧan, A., Ervynck, A., Fulgione, D., Gligor, M., Götherström, A., Gourichon, L., Groenen, M. A. M., Helmer, D., Hongo, H., Horwitz, L. K., Irving-Pease, E. K., Lebrasseur, O., Lesur, J., Malone, C., Manaseryan, N., Marciniak, A., Martlew, H., Mashkour, M., Matthews, R., Matuzeviciute, G. M., Maziar, S., Meijaard, E., McGovern, T., Megens, H. J., Miller, R., Mohaseb, A. F., Orschiedt, J., Orton, D., Papathanasiou, A., Pearson, M. P., Pinhasi, R., Radmanović, D., Ricaut, F. X., Richards, M., Sabin, R., Sarti, L., Schier, W., Sheikhi, S., Stephan, E., Stewart, J. R., Stoddart, S., Tagliacozzo, A., Tasić, N., Trantalidou, K., Tresset, A., Valdiosera, C., Van Den Hurk, Y., Van Poucke, S., Vigne, J. D., Yanevich, A., Zeeb-Lanz, A., Triantafyllidis, A., Gilbert, M. T. P., Schibler, J., Rowley-Conwy, P., Zeder, M., Peters, J., Cucchi, T., Bradley, D. G., Dobney, K., Burger, J., Evin, A., Girdland-Flink, L. & Larson, G., 27 Aug 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 35, p. 17231-17238 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
8 Citations (Scopus)

Author Correction: Hotspots of recent hybridization between pigs and wild boars in Europe

Iacolina, L., Pertoldi, C., Amills, M., Kusza, S., Megens, H. J., Bâlteanu, V. A., Bakan, J., Cubric-Curik, V., Oja, R., Saarma, U., Scandura, M., Šprem, N. & Stronen, A. V., 24 Dec 2019, In : Scientific Reports. 9, 1, 20187.

Research output: Contribution to journalComment/Letter to the editorAcademic

Open Access

Deleterious alleles in the context of domestication, inbreeding, and selection

Bosse, M., Megens, H-J., Derks, M. F. L., de Cara, Á. M. R. & Groenen, M. A. M., 2019, In : Evolutionary Applications. 12, 1, p. 6-17

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
10 Citations (Scopus)

Detection of a Frameshift Deletion in the SPTBN4 Gene Leads to Prevention of Severe Myopathy and Postnatal Mortality in Pigs

Derks, M. F. L., Harlizius, B., Lopez, M. S., Greijdanus-van der Putten, S., Dibbits, B. W., Laport, K., Megens, H. J. W. C. & Groenen, M., 26 Nov 2019, In : Frontiers in Genetics Livestock Genomics. 10, 9 p., 1226.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Effect of population bottlenecks on patterns of deleterious variation in small captive populations

Bortoluzzi, C., Bosse, M., Derks, M. F. L., Crooijmans, R. P. M. A., Groenen, M. & Megens, H. J. W. C., 26 Aug 2019, Book of Abstracts of the 70th Annual Meeting of the European Federation of Animal Science. Wageningen: Wageningen Academic Publishers, p. 106-106 (Book of Abstracts).

Research output: Chapter in Book/Report/Conference proceedingAbstract

Open Access

Genomic analysis on pygmy hog reveals extensive interbreeding during wild boar expansion

Liu, L., Bosse, M., Megens, H-J., Frantz, L. A. F., Lee, Y. L., Irving-Pease, E. K., Narayan, G., Groenen, M. A. M. & Madsen, O., 1 Dec 2019, In : Nature Communications. 10, 1992.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
3 Citations (Scopus)

Impact of merging commercial breeding lines on the genetic diversity of Landrace pigs

Hulsegge, I., Calus, M., Hoving-Bolink, R., Lopes, M., Megens, H. J. & Oldenbroek, K., 29 Oct 2019, In : Genetics Selection Evolution. 51, 1, 60.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Loss of function mutations in essential genes cause embryonic lethality in pigs

Derks, M. F. L., Gjuvsland, A. B., Bosse, M., Lopes, M. S., van Son, M., Harlizius, B., Tan, B. F., Hamland, H., Grindflek, E., Groenen, M. A. M. & Megens, H. J., 1 Mar 2019, In : Plos Genetics. 15, 3, p. e1008055

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
7 Citations (Scopus)
Open Access

The genomes of Poeciliopsis retropinna and Poeciliopsis turrubarensis reflect differences in reproductive strategy

van Kruistum, H., Guernsey, M. W., Baker, J. C., Kloet, S. L., Groenen, M. A. M., Pollux, B. J. A. & Megens, H. J., Aug 2019.

Research output: Contribution to conferenceAbstract

The little Pygmy hog (Porcula salvania), a big piece in resolving the fascinating history of the complex speciation of the Suidae

Liu, L., Bosse, M., Megens, H. J. W. C., Frantz, L. A. F., Lee, Y. L., Irving-Pease, E. K., Narayan, G., Groenen, M. & Madsen, O., 9 Jul 2019, ISAG 2019 Abstracts Book: 37th International Society for Animal Genetics Conference, July 7-12, 2019 - Lleida, Spain. p. 24-25

Research output: Chapter in Book/Report/Conference proceedingAbstract

2018
Open Access
Open Access
2 Citations (Scopus)

A survey of deleterious variation in highly managed pig populations

Derks, M. F. L., Megens, H. J. W. C., Bosse, M., Lopes, M. S., Harlizius, B. & Groenen, M., 24 Feb 2018, Proceedings of the 11th World Congress on Genetics Applied to Livestock Production. 7 p. 11.522

Research output: Chapter in Book/Report/Conference proceedingConference paper

Open Access

A survey of functional genomic variation in domesticated chickens

Derks, M. F. L., Megens, H. J., Bosse, M., Visscher, J., Peeters, K., Bink, M. C. A. M., Vereijken, A., Gross, C., De Ridder, D., Reinders, M. J. T. & Groenen, M. A. M., 16 Apr 2018, In : Genetics Selection Evolution. 50, 1, 17.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
6 Citations (Scopus)

Balancing selection on a recessive lethal deletion with pleiotropic effects on two neighboring genes in the porcine genome

Derks, M. F. L., Lopes, M. S., Bosse, M., Madsen, O., Dibbits, B., Harlizius, B., Groenen, M. A. M. & Megens, H. J., 19 Sep 2018, In : Plos Genetics. 14, 9, 20 p., e1007661.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
3 Citations (Scopus)

Diversiteit en krielonderzoek: bij de traditionele Nederlandse hoenderrassen

Bortoluzzi, C., Megens, H. J. W. C., Crooijmans, R. P. M. A., de Boer, H., Taks, A., Kroon, P. & Hoving, A. H., Jun 2018, In : Kleindier magazine. 132, 6, p. 11-13

Research output: Contribution to journalArticleProfessional

Open Access

Diversiteit en krielonderzoek bij de traditionele Nederlandse hoenderrassen

Bortoluzzi, C., Megens, H. J. W. C., Crooijmans, R. P. M. A., de Boer, H., Taks, A., Kroon, P. & Hoving, A. H., 2018, In : Zeldzaam huisdier. 43, 3, p. 20-21

Research output: Contribution to journalArticleProfessional

Early and late feathering in Turkey and chicken: Same gene but different mutations

Derks, M. F. L., Herrero-Medrano, J. M., Crooijmans, R. P. M. A., Vereijken, A., Long, J. A., Megens, H. J. & Groenen, M. A. M., 22 Mar 2018, In : Genetics Selection Evolution. 50, 1, 7.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
5 Citations (Scopus)

Hotspots of recent hybridization between pigs and wild boars in Europe

Iacolina, L., Pertoldi, C., Amills, M., Kusza, S., Megens, H. J., Bâlteanu, V. A., Bakan, J., Cubric-Curik, V., Oja, R., Saarma, U., Scandura, M., Šprem, N. & Stronen, A. V., 1 Dec 2018, In : Scientific Reports. 8, 1, 17372.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
5 Citations (Scopus)

Impact of merging different commercial lines on genetic diversity of the Dutch Landrace pigs

Hulsegge, B., Calus, M. P. L., Hoving-Bolink, A. H., Lopes, M. S., Megens, H. J. W. C. & Oldenbroek, J. K., 27 Aug 2018, Book of Abstracts of the 69th Annual Meeting of the European Federation of Animal Science. Wageningen: Wageningen Academic Publishers, p. 554-554 (Book of abstracts; no. 24).

Research output: Chapter in Book/Report/Conference proceedingAbstract

7 Citations (Scopus)
Open Access
8 Citations (Scopus)
Open Access
Open Access
2017

A genomic perspective about wild boar demography and evolution

Amills, M., Megens, H. J. W. C., Manunza, A., Ramos-Onsins, S. E. & Groenen, M., 2017, Ecology, Conservation and Management of Wild Pigs and Peccaries. Melletti, M. & Meijaard, E. (eds.). Cambridge University Press, p. 376-387

Research output: Chapter in Book/Report/Conference proceedingChapter

A history of hybrids? Genomic patterns of introgression in the True Geese

Ottenburghs, J., Megens, H. J., Kraus, R. H. S., van Hooft, P., van Wieren, S. E., Crooijmans, R. P. M. A., Ydenberg, R. C., Groenen, M. A. M. & Prins, H. H. T., 2017, In : BMC Evolutionary Biology. 17, 1, 201.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
9 Citations (Scopus)
Open Access

A systematic survey to identify lethal recessive variation in highly managed pig populations

Derks, M. F. L., Megens, H. J., Bosse, M., Lopes, M. S., Harlizius, B. & Groenen, M. A. M., 9 Nov 2017, In : BMC Genomics. 18, 1, 858.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
12 Citations (Scopus)

Distribution and functionality of copy number variation across European cattle populations

Upadhyay, M., Da Silva, V. H., Megens, H. J., Visker, M. H. P. W., Ajmone-Marsan, P., Bâlteanu, V. A., Dunner, S., Garcia, J. F., Ginja, C., Kantanen, J., Groenen, M. A. M. & Crooijmans, R. P. M. A., 2017, In : Frontiers in Genetics. 8, 12 p., 108.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
14 Citations (Scopus)

Fine-mapping of BTA17 using imputed sequences for associations with de novo synthesized fatty acids in bovine milk

Duchemin, S. I., Bovenhuis, H., Megens, H. J., Van Arendonk, J. A. M. & Visker, M. H. P. W., Nov 2017, In : Journal of Dairy Science. 100, 11, p. 9125-9135

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
4 Citations (Scopus)

Genetic origin, admixture and population history of aurochs (Bos primigenius) and primitive European cattle

Upadhyay, M. R., Chen, W., Lenstra, J. A., Goderie, C. R. J., MacHugh, D. E., Park, S. D. E., Magee, D. A., Matassino, D., Ciani, F., Megens, H. J., van Arendonk, J. A. M. & Groenen, M. A. M., 2017, In : Heredity. 118, p. 169-176

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
33 Citations (Scopus)

Genome-wide SNP data unveils the globalization of domesticated pigs

Yang, B., Cui, L., Pérez-Enciso, M., Traspov, A., Crooijmans, R. P. M. A., Zinovieva, N., Schook, L. B., Archibald, A., Gatphayak, K., Knorr, C., Triantafyllidis, A., Alexandri, P., Semiadi, G., Hanotte, O., Dias, D., Dovč, P., Uimari, P., Iacolina, L., Scandura, M., Groenen, M. A. M. & 2 others, Huang, L. & Megens, H. J., 2017, In : Genetics, Selection, Evolution. 49, 15 p., 71.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
35 Citations (Scopus)

Survey of deleterious variants in highly managed commercial layer lines

Derks, M. F. L., Megens, H. J. W. C., Bosse, M., Gross, C., Reijnders, M., de Ridder, D. & Groenen, M., Apr 2017.

Research output: Contribution to conferencePosterAcademic

The impact of genome editing on the introduction of monogenic traits in livestock

Bastiaansen, J. W. M., Bovenhuis, H., Groenen, M., Megens, H. J. W. C. & Mulder, H. A., 2017, Book of Abstracts of the 68th Annual Meeting of the European Federation of Animal Science. Wageningen: Wageningen Academic Publishers, p. 428-428 (Book of abstracts; no. 23).

Research output: Chapter in Book/Report/Conference proceedingAbstract

2016

Accuracy of genomic prediction using imputed whole-genome sequence data in white layers

Heidaritabar, M., Calus, M. P. L., Megens, H. J., Vereijken, A., Groenen, M. A. M. & Bastiaansen, J. W. M., 2016, In : Journal of Animal Breeding and Genetics. p. 167-179 3.

Research output: Contribution to journalArticleAcademicpeer-review

21 Citations (Scopus)
13 Citations (Scopus)
Open Access

Distinguishing migration events of different timing for wild boar in the Balkans

Alexandri, P., Megens, H. J. W. C., Crooijmans, R. P. M. A., Groenen, M., Goedbloed, D. J., Herrero Medrano, J. M., Rund, L. A., Schook, L. B., Chatzinikos, E., Triantaphyllidis, C. & Triantafyllidis, A., 1 Oct 2016, In : Journal of Biogeography. 44, 2, p. 259-270

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)